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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Oxygen and Nitrogen Effects on MC Carbide in K465 Nickel-Base Superalloy显示文摘Effects of oxygen and nitrogen on MC carbide in nickel-base superalloy K465 were investigated, because neither of the two gas elements was found to decide MC carbide morphology monotonically. The morphology of MC carbide under alloy solidified in conventional investment casting condition was observed to transform from script-type to block-type with the total oxygen and nitrogen content (gas content) in samples rising up from 1.2×10-6 mol/g to 2.6×10-6 mol/g. The area fraction and composition of the MC carbide also varied with increase of gas content. However, the morphology of MC carbide kept to be script-type even when gas content was up to 3.4×10-6 mol/g in samples solidified with a much higher cooling rate. These results indicate that effects of gas content on formation of MC carbide can be observed in specimens solidified with low cooling rate, but such changes in MC carbide cannot be found when the cooling rate is high. | Wang L N Zheng Q Sun X F Guan H R Hu Z Q | 2009 | 稀有金属材料与工程2009，38，A03： | 4 |
| 3 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 4 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 5 | 地中海膳食干预研究中来自胆碱通路的血浆代谢物与心血管病风险的关系显示文摘血浆甜菜碱水平以及胆碱代谢水平与主要心血管病终点之间的联系仍不清楚。研究者评估了胆碱通路的代谢物与偶发心血管病风险以及地中海膳食干预的潜在调节效应之间的相关性。 | 黄洁 叶鹏 Guasch-Ferré M Hu FB Ruiz-Canela M Bulló M Toledo E Wang DD Corella D Gómez-Gracia E Fiol M Estruch R Lapetra J Fitó M Arós F Serra-Majem L Ros E Dennis C Liang L Clish CB Martínez-González MA Salas-Salvadó J | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 6 | 显示文摘 | Cheng X Y Xu X F Hu R X | 2007 | Acta Phys Sin2007，56，： | 1 |
| 7 | Aerobic degradation and photolysis of tylosin in water and soil 显示文摘 | Hu D F Coats J R | 2007 | Environmental Toxicology and Chemistry2007，26，5： | 1 |
| 8 | Molecular biomarker evidence of origins and transport of organic matter in sediments of the Pearl River Estuary and adjacent South China Sea 显示文摘 | HU J F PENG P A CHIVAS A R | 2009 | Applied Geochemistry2009，24，9： | 1 |
| 9 | Major ion chemistry of some large Chinese rivers 显示文摘 | Hu M H Stallard R F Edmond J M | 1982 | Nature1982，298，5874： | 1 |
| 10 | 查看详情显示文摘 | J R Sun F X Hu B G Shen | | 0，，： | 1 |
| 11 | Preparation and tribological properties of nanometer magnesium borate as lubricating oil additive 显示文摘 | Hu Z S Lai R Lou F | 2002 | Wear2002，252，56： | 1 |
| 12 | Variations and trends of onset, cessation and length of climatic growing season over Xinjiang, NW China显示文摘 | Jiang F Q R J Hu | 2011 | Theoretical and Applied Climatology2011，34，106： | 1 |
| 13 | The synthesis and electrochemicalperformance of LiV3 08 cathode with lanthanum - doped 显示文摘 | Hu F Sun M R Wu Y S | 2012 | AdvancedMaterials Research2012，860，： | 1 |
| 14 | New constructions of bal- anced Boolean functions with high nonlinearity and optimal algebraic degree 显示文摘 | ZHANG F R HU Y P JIA Y Y | 2012 | International Journal of Computer Mathematics2012，89，10： | 1 |
| 15 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 16 | Preparation and characterization of flame retardant ABS/montmorillonite nanocomposlte 显示文摘 | Wang S F Hu Y Zong R W | 2004 | Applied Clay Science2004，25，： | 1 |
| 17 | Thermogravimetric evaluation of PC/ABS/montmorillonite Nanocomposite显示文摘 | ZONG R W HU Y WANG S F | 2004 | Polym Degrad Stab2004，83，： | 1 |
| 18 | Preparation and properties of a novel polytriazole resin显示文摘 | Wan L Q Hu Y H Huang F R Du L | 2007 | Journal of Applied polymer Science2007，104，2： | 1 |
| 19 | Approximate solution of creep of orthogonal anisotropic concrete thin plates 显示文摘 | Zhou R G Hu Y X Duan L Chen W F | 1993 | Engineering Structure1993，15，1： | 1 |
| 20 | A covariance structure analysis of flicker sensitivity显示文摘 | Mayer M J Dougherty R F Hu L | 1995 | Vision Research1995，53，11： | 1 |
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