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| 1 | Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012显示文摘Objective To characterize the histological and epidemiological features of male lung cancer patients in China. Methods The demographic and histological information about male lung cancer patients identified from 2000-01-01 to 2012-12-31,was collected from the Cancer Hospital of the Chinese Academy of Medical Sciences. Relative frequencies(RF) were estimated for major histological subtypes and compared according to the years of diagnosis and birth. Results The RF of adenocarcinoma(ADC) increased from 21.96% to 43.36% and the RF of squamous cell carcinoma(SCC) decreased from 39.11% to 32.23% from 2000 to 2012 in the 15 427 male lung cancer patients included in this study(Z=17.909,P<0.0001; Z=-6.117,P<0.0001). The RF of ADC increased from 28.72% in 2000-2004,36.88% in 2005-2008 to 48.61% in 2009-2012 in patients born after 1960. The age-adjusted RF of ADC in 2007-2012 increased consistently in all the investigated areas. Conclusion The increased RF of ADC in male lung cancer patients highlights the need for further investigation of the etiologic factors of these tumors. Smoke-free policies rather than modifying tobacco products should be enforced. | ZOU Xiao Nong LIN Dong Mei WAN Xia CHAO Ann FENG Qin Fu DAI Zhen YANG Gong Huan LV Ning | 2014 | Biomedical and Environmental Sciences2014，27，1： | 19 |
| 2 | Cbl-b and PI3K/Akt pathway are differently involved in oxygen- glucose deprivation preconditioning in PC12 cells显示文摘 | Zhang Wei Yu Huan Zou Wei Wang Yan-fu Liang Xiao-feng Zhang Bo Kong Jing-jing Li Pai Zhang Duo-duo Yin Lin | 2013 | Chinese Medical Journal2013，，21： | 10 |
| 3 | Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype. | Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu | 2021 | Cell Research2021，31，3： | 9 |
| 4 | Preparation and Characterization of Flame Retardant and Low Smoke Releasing Oil-resistant EVA/NBR Blends显示文摘Nano-Si O2 and/or Mo O3 were introduced to ethylene-vinyl acetate/nitrile butadiene rubber(EVA/NBR) blends containing magnesium hydroxide(MH) and red phosphorus(RP) to further improve the mechanical properties, oil resistance, smoke suppression and flame retardancy. The results indicated that the tensile strength and oil resistance were significantly improved by incorporating nano-Si O2. Smoke suppression tests for EVA/NBR blend samples showed that both nano-Si O2 and Mo O3 can significantly reduce smoke release amount. The flammability characterization indicated that the blended sample with an LOI value of 33.0 could achieve V-0 level in the UL-94 test. Cone calorimetry test data showed the peak heat release rate was 67% lower than that for pure EVA/NBR. Thermal analysis showed that the presence of both nano-Si O2 and Mo O3 was beneficial to promoting char formation of the EVA/NBR blends. Char residual analysis suggested that Mo O3 aggregated in solid phase during combustion. | Huan Zou Jun Sun Xiao-yu Gu Peng Jiang Xi-shan Liu 张胜 | 2015 | Chinese Journal of Polymer Science2015，33，4： | 8 |
| 5 | Polymorphisms of angiotensin-converting enzyme 2 gene associated with magnitude of left ventricular hypertrophy in male patients with hypertrophic cardiomyopathy显示文摘背景:甚至带一个相同基因变化,内部家庭并且 intra 家庭变化当面全球被注意了并且在有亢奋的营养的心肌症(HCM ) 的病人的左心室肥大和猝死的严厉。修饰词基因可以贡献差异。变换血管收缩素的酶 2 (ACE2 ) 基因被建立了在社区与左心室肥大的参数被联系基于的男题目。现在的学习的目的是与 HCM 的显型调查 ACE2 基因多型性的协会。方法:261 个连续 HCM 病人和 609 健康控制的一个总数被注册进这研究。rs2106809 和 rs6632677 的多型性是由聚合酶链反应限制碎片长度多型性(PCR-RFLP ) 的 genotyped 并且由定序证实了。逻辑回归当模特儿,多,变量分析被用来决定机会比率(或) 并且为 HCM 的 ACE2 的变化的 95% 信心间隔(CI ) 。结果:rs2106809 的 T 等位基因和 rs6632677 的 C 等位基因为 HCM 授与增加的风险(或 1.34, 95% CI 1.01 - 1.77, P = 0.04;或 1.11 ,95% CI 1.03 - 1.21 , P = 0.002 ,分别地),并且 2 单个核苷酸多型性( SNP )在强壮的连接不平衡( LD ), TC haplotype 独立地与被联系一更高或为 HCM (或= 1.59 ,95% CI 1.21 - 1.87 )在为常规风险因素调整了以后。并且风险等位基因与被联系更厚内部 HCM 的室的氏族的厚度((20.0 +/- 6.3 ) 公里对(17.9 +/- 5.5 ) 公里, P = 0.03 并且(21.3 +/- 5.9 ) 公里对(17.9 +/- 5.8 ) 公里, P = 0.04,分别地) 。没有协会与 HCM 与女病人一起在二多型性之间被发现。结论:ACE2 基因力量的次要的等位基因是为在有 HCM 的男病人的左心室肥大的大小的基因修饰词。 | WANG Shu-xia FU Chun-yan ZOU Yu-bao WANG Hu SHI Yi XU Xi-qi CHEN Jing-zhou SONG Xiao-dong HUAN Tu-jun HUI Ru-tai | 2008 | Chinese Medical Journal2008，，1： | 8 |
| 6 | Transcriptomic analyses identify albino-associated genes of a novel albino tea germplasm ‘Huabai 1’显示文摘Albinism in shoots of tea plants is a common phenotypic expression which gives the tea infusion a pleasant umami taste.A novel natural albino mutant tea germplasm containing high amino acids content was found and named as‘Huabai 1’.‘Huabai 1’has white jade tender shoots under low temperature and turns green with increased temperature.In order to understand the molecular mechanism of color change in leaf of‘Huabai 1’,transcriptome analysis was performed to identify albino-associated differentially expressed genes(DEGs).A total of 483 DEGs were identified from white shoots of‘Huabai 1’compared to its green shoots.There were 15 DEGs identified to be involved in phenylpropanoid biosynthesis,which account for the majority of characterized DEGs.The metabolites related to phenylpropanoid biosynthesis revealed similar expression pattern of DEGs.Furthermore,metabolic pathways such as ubiquonone,tyrosine,and flavonoid biosynthesis associated with phenylpropanoid biosynthesis could also contribute to the color change in‘Huabai 1’tender shoots.Protein–protein interaction analysis revealed a hub protein NEDD8(CSA009575)which interacted with many regulated genes in spliceosome,nitrogen metabolism,phenylpropanoid biosynthesis,and other pathways.In conclusion,the findings in this study indicate that the color change of‘Huabai 1’tender shoots is a combined effect of phenylpropanoid biosynthesis pathway and other metabolic pathways including flavonoid biosynthesis in tea plants.Chlorophyll biosynthesis-related genes LHCII and SGR may also play some roles in color change of‘Huabai 1’. | Qingping Ma Huan Li Zhongwei Zou Emmanuel Arkorful Qianru Lv Qiongqiong Zhou Xuan Chen Kang Sun Xinghui Li | 2018 | Horticulture Research2018，5，1： | 7 |
| 7 | Abnormal Degree Centrality of Bilateral Putamen and Left Superior Frontal Gyrus in Schizophrenia with Auditory Hallucinations: A Resting-state Functional Magnetic Resonance Imaging Study显示文摘 | Cheng Chen Hui-Ling Wang Shi-Hao Wu Huan Huang Ji-Lin Zou Jun Chen Tian-Zi Jiang Yuan Zhou Gao-Hua Wang | 2015 | Chinese Medical Journal2015，，23： | 6 |
| 8 | Clinical features of ankylosing spondylitis associated with acute anterior uveitis in Chinese patients显示文摘AIM: To characterize the clinical features, diagnosis, treatment and prognosis of uveitis associated with ankylosing spondylitis (AS) in Chinese patients. · METHODS: Two hundred and three patients with uveitis associated with AS followed-up in the Third Military Medical University Daping Hospital between 2005 and 2010 were retrospectively evaluated in this study. Complete ophthalmological examinations were evaluated at baseline and during the follow-up period. The gender, age, follow-up time, mean frequency of uveitis onset, and accompanying eye examination findings, history, demographical parameters were reviewed. All the patients presented complete clinical and radiologic (sacroiliac, lumbar, dorsal and cervical spine, knee, ankle, shoulder, hip, elbow) evaluation. HLA-B27 typing was also searched. · RESULTS: There were 203 patients diagnosed with AS associated uveitis. All showed sacroiliac X-ray changes indicative of AS. There were 184 male and 19 female patients. The average age of patients was 35±12 (range 18-50). Mean follow-up period was 2.4 years (1-5 years). Acute anterior uveitis was the most common type of uveitis in both genders. 121 eyes presented unilateral involvement (55.2%), and 92 eyes presented bilateral involvement (45.3%) with onset alternately. 22 eyes occurred hypopyon, 16 eyes were found anterior vitreous cells, 7 eyes were noted reactive macular edema or exudation, 29 eyes presented posterior synechiae of iris, and 14 eyes presented cataract, 9 eyes presented secondary glaucoma, 2 eyes presented bend corneal degeneration and 1 eyes presented atrophy of eyeball. At the final visit, uveitis was well controlled in most patients. · CONCLUSION: AS associated with uveitis in Chinese patients mainly manifests as acute anterior uveitis. A combination of corticosteroids with other mydriasis agents is effective for most AS associated with uveitis patients. In general, the prognosis is good in these cases. | Shu-Xing Ji, Huan Zou | 2012 | International Journal of Ophthalmology(English edition)2012，5，2： | 5 |
| 9 | Space-confined growth of monolayer ReSe2 under a graphene layer on Au foils显示文摘Vertical heterostructures based on two-dimensional(2D)materials have attracted widespread interest for their numerous applications in electronic and optoelectronic devices.Herein,we report the direct construct!on of an abnormal graphene/ReSe2 stack on Au foils by a two-step chemical vapor deposition(CVD)strategy.During the second growth stage,mono layer ReSe2 is found to prefere ntially evolve at the irUerface between the first-grown graphene layer and the Au substrate.The unusual stacking behavior is unraveled by in-situ'cutting open'the upper graphene from the defects to expose the lower ReSe2 using scanning tunneling microscopy(STM).From combination of these results with density functional theory calculations,the domain boundaries and edge sites of graphene are proposed to be adsorption sites for Re and Se precursors,further facilitating the growth of ReSe2 at the van der Waals gap of graphene/Au.This work hereby offers an intriguing strategy for obtaining vertical 2D heterostructures featured with an ultra-clean interface and a designed stacking geometry. | Chunyu Xie Shaolong Jiang Xiaolong Zou Yuanwei Sun Liyun Zhao Min Hong Shulin Chen Yahuan Huan Jianping Shi Xiebo Zhou Zhepeng Zhang Pengfei Yang Yuping Shi Porun Liu Qing Zhang Peng Gao Yanfeng Zhang | 2019 | Nano Research2019，12，1： | 4 |
| 10 | A multicenter prospective study of next-generation sequencing-based newborn screening for monogenic genetic diseases in China显示文摘Background Newborn screening(NBS)is an important and successful public health program that helps improve the long-term clinical outcomes of newborns by providing early diagnosis and treatment of certain inborn diseases.The develop-ment of next-generation sequencing(NGS)technology provides new opportunities to expand current newborn screening methodologies.Methods We designed a a newborn genetic screening(NBGS)panel targeting 135 genes associated with 75 inborn disorders by multiplex PCR combined with NGS.With this panel,a large-scale,multicenter,prospective multidisease analysis was conducted on dried blood spot(DBS)profiles from 21,442 neonates nationwide.Results We presented the positive detection rate and carrier frequency of diseases and related variants in different regions;and 168(0.78%)positive cases were detected.Glucose-6-Phosphate Dehydrogenase deficiency(G6PDD)and phenylketonuria(PKU)had higher prevalence rates,which were significantly different in different regions.The positive detection of G6PD variants was quite common in south China,whereas PAH variants were most commonly identified in north China.In addi-tion,NBGS identified 3 cases with DUOX2 variants and one with SLC25A13 variants,which were normal in conventional NBS,but were confirmed later as abnormal in repeated biochemical testing after recall.Eighty percent of high-frequency gene carriers and 60%of high-frequency variant carriers had obvious regional differences.On the premise that there was no significant difference in birth weight and gestational age,the biochemical indicators of SLC22A5 c.1400C>G and ACADSB c.1165A>G carriers were significantly different from those of non-carriers.Conclusions We demonstrated that NBGS is an effective strategy to identify neonates affected with treatable diseases as a supplement to current NBS methods.Our data also showed that the prevalence of diseases has significant regional charac-teristics,which provides a theoretical basis for screening diseases in different regions. | Ru-Lai Yang Gu-Ling Qian Ding-Wen Wu Jing-Kun Miao Xue Yang Ben-Qing Wu Ya-Qiong Yan Hai-Bo Li Xin-Mei Mao Jun He Huan Shen Hui Zou Shu-Yuan Xue Xiao-Ze Li Ting-Ting Niu Rui Xiao Zheng-Yan Zhao | 2023 | World Journal of Pediatrics2023，19，7： | 4 |
| 11 | Fluorination-substitution effect on all-small-molecule organic solar cells显示文摘Due to the strong crystallinity and anisotropy of small molecules, matched molecular photoelectric properties and morphologies between small molecules and non-fullerene acceptors are especially important in all-small-molecule organic solar cells(OSCs).Introducing fluorine atoms has been proved as an effective strategy to achieve a high device performance through tuning molecular energy levels, absorption and assembly properties. Herein, we designed a novel benzodithiophene-based small molecule donor BDTF-CA with deep highest occupied molecular orbital(HOMO) energy level. All-small-molecule OSCs were fabricated by combing non-fullerene acceptor IDIC with different fluorine-atom numbers. Two or four fluorine atoms were introduced to the end-capped acceptor of IDIC, which are named as IDIC-2 F and IDIC-4 F, respectively. With the increase of fluorination from IDIC to IDIC-4 F, the open circuit voltage(Voc) of the devices decreased, while hole and electron mobilities of the active layers increased by one order of magnitude. Contributed to the most balanced Voc, short-circuit current(Jsc) and fill factor(FF), the device based on BDTF-CA/IDIC-2 F achieved the highest power conversion efficiency of 9.11%. | Qiong Wu Dan Deng Jianqi Zhang Wenjun Zou Yang Yang Zhen Wang Huan Li Ruimin Zhou Kun Lu Zhixiang Wei | 2019 | Science China Chemistry2019，62，7： | 3 |
| 12 | Combining chlorination and sulfuration strategies for high-performance all-small-molecule organic solar cells显示文摘Three small-molecule donors based on dithieno [2,3-d:2’,3 ’-d’]-benzo[1,2-b:4,5-b’] dithiophene(DTBDT)unit were designed and synthesized by side chain regulation with chlorinated or/and sulfurated substitutions(namely ZR1,ZR1-Cl,and ZR1-S-Cl respectively),along with a crystalline non-fullerene acceptor IDIC-4 Cl with a chlorinated 1,1-dicyanomethylene-3-indanone(IC) end group.Energy levels,molar extinction coefficients and crystallinities of three donor molecules can be effectively altered by combining chlorination and sulfuration strategies.Especially,the ZR1-S-Cl exhibited the best absorption ability,lowest higher occupied molecular orbital(HOMO) energy level and highest crystallinity among three donors,resulting in the corresponding all-small-molecule organic solar cells to produce a high power conversion efficiency(PCE) of 12.05% with IDIC-4 Cl as an acceptor. | Ruimin Zhou Chen Yang Wenjun Zou Muhammad Abdullah Adil Huan Li Min Lv Ziyun Huang Menglan Lv Jianqi Zhang Kun Lu Zhixiang Wei | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 13 | The Xanthomonas typeⅢeffector Xop AP prevents stomatal closure by interfering with vacuolar acidification显示文摘Plant stomata close rapidly in response to a rise in the plant hormone abscisic acid(ABA)or salicylic acid(SA)and after recognition of pathogenassociated molecular patterns(PAMPs).Stomatal closure is the result of vacuolar convolution,ion efflux,and changes in turgor pressure in guard cells.Phytopathogenic bacteria secrete typeⅢeffectors(T3Es)that interfere with plant defense mechanisms,causing severe plant disease symptoms.Here,we show that the virulence and infection of Xanthomonas oryzae pv.oryzicola(Xoc),which is the causal agent of rice bacterial leaf streak disease,drastically increased in transgenic rice(Oryza sativa L.)plants overexpressing the Xoc T3E gene Xop AP,which encodes a protein annotated as a lipase.We discovered that Xop AP binds to phosphatidylinositol 3,5-bisphosphate(Ptd Ins(3,5)P_(2)),a memb rane phospholipid that functions in p H control in lysosomes,membrane dynamics,and protein trafficking.Xop AP inhibited the acidification of vacuoles by competing with vacuolar H^(+)-pyrophosphatase(V-PPase)for binding to Ptd Ins(3,5)P_(2),leading to stomatal opening.Transgenic rice overexpressing Xop AP also showed inhibition of stomatal closure when challenged by Xoc infection and treatment with the PAMP flg22.Moreover,Xop AP suppressed flg22-induced gene expression,reactive oxygen species burst and callose deposition in host plants,demonstrating that Xop AP subverts PAMP-triggered immunity during Xoc infection.Taken together,these findings demonstrate that Xop AP overcomes stomatal immunity in plants by binding to lipids. | Longyu Liu Ying Li Zhengyin Xu Huan Chen Jingyi Zhang Brittany Manion Fengquan Liu Lifang Zou Zheng Qing Fu Gongyou Chen | 2022 | Journal of Integrative Plant Biology2022，64，10： | 3 |
| 14 | A-π-D-π-A small-molecule donors with different end alkyl chains obtain different morphologies in organic solar cells显示文摘For bulk-heterojunction organic solar cells, the morphology of the blend films highly influence the exciton dissociation and charge transport process. In this work, two novel A-π-D-π-A(A represents the acceptor unit and D represents the donor unit) backbone structure small molecular electron donors based on two dimensional conjugated naphtho[1,2-b:5,6-b']dithiophene(NDT) with different end alkyl chains, named as NDT-3T-EH and NDT-3T-O, have been designed and synthesized. The photovoltaic property of NDT-3T-O-based device is better than that of the NDT-3T-EH and the best efficiency reaches 7.06%, and the photovoltaic property of NDT-3T-EH reaches 6.11%. The difference in the performance should be attributed to the different morphology and phase separation resulted from the different crystallinity and aggregation ability of two donors. The results demonstrate that the optimized end alkyl chains can be used to design A-π-D-π-A backbone structure small molecular electron donors for smallmolecule organic solar cells. | Yanan Shi Chen Yang Huan Li Lixuan Liu Ruimin Zhou Wenjun Zou Zhen Wang Qiong Wu Dan Deng Jianqi Zhang Kun Lu Zhixiang Wei | 2019 | Chinese Chemical Letters2019，30，4： | 3 |
| 15 | Estimation of Sediment Incipient Velocity Using B-Mode Ultrasound Imaging Technique显示文摘Sediment incipient velocity(SIV) is a vital parameter for sediment research and river dynamics. This paper describes a novel method of estimating SIV based on the known flow velocity in the movable-bed model experiment. In this method, we use B-mode ultrasound imaging technique to get video images of moving particles and topography under water. By statistical analysis of video images, the relationship between the average number of imaging particles and flow velocity is obtained. The relationship between the change rate of average number and flow velocity is analyzed in sediment incipient process. These relationships are used to estimate the SIV. Lastly, the changed topography verifies the estimated velocity. The results show there is a sudden change in these relationships which can be used to estimate the SIV with high resolution by using a B-mode ultrasound device. The estimated SIV of plastic sands(particle size is about 0.25 mm) is 3.64 cm · s–1 and the estimated SIV of natural sands(particle size is about 0.25 mm) is 5.47 cm · s–1 in the same condition. | SONG Huan ZOU Xianjian | 2015 | Wuhan University Journal of Natural Sciences2015，20，2： | 2 |
| 16 | Factors involved in the success of Castanea henryi stem cuttings in different cutting mediums and cutting selection periods显示文摘Chinquapin(Castanea henryi) is a dual-purpose tree species in China valued for as a source of timber and starch.We investigated the effect of four cutting mediums(pure vermiculite;peat:river sand at 3:1 v/v;peat:krasnozem at 1:1 v/v;and pure krasnozem) and three stem cutting periods(March,May,and July) on rooting performance of C.henryi cuttings.Different cutting periods and cutting mediums greatly influenced the rooting rate of C.henryi,ranging from 3.35 to 77.31%.Principal component analysis indicated that the best combination of cutting period and cutting medium was semi-hardwood cuttings(May cuttings)+krasnozem.Histological evidence indicated that adventitious root initials were present by week 5-6,and that the site of root primordia initiation was observed in the vascular cambium.Stem anatomical structures observed at different periods indicated that a xylem/radius ratio of29.90-37.42% and a fractured phloem fiber ring are indicative of rooting success.The relational model between rooting index and medium properties indicated that nutrient content and porosity significantly influenced callus production.However,pH strongly affected C.henryi root formation,with the Pearson correlation coefficients for May and July cuttings of-0.856 and-0.947,respectively.Our protocol is helpful to achieve mass clone propagation of improved C.henryi genotypes,thus overcoming a common hurdle in chinquapin breeding programs. | Wangzun Chen Libing He Shiyi Tian Joseph Masabni Huan Xiong Feng Zou Deyi Yuan | 2021 | Journal of Forestry Research2021，32，4： | 2 |
| 17 | Long-term exposure to imatinib reduced cancer stem cell ability through induction of cell differentiation via activation of MAPK signaling in glioblastoma cells显示文摘 | Yucui Dong Qinglian Han Yan Zou Zhenling Deng Xinliang Lu Xiaohua Wang Weihua Zhang Hua Jin Jun Su Tao Jiang Huan Ren | 2012 | Molecular and Cellular Biochemistry2012，，1： | 2 |
| 18 | Large-area, Flexible Polymer Solar Cell Based on Silver Nanowires as Transparent Electrode by Roll-to-Roll Printing显示文摘Conventional organic solar cell's(OSC) architectures, including rigid transparent substrate(Glass), conductive electrode(Indium tin oxide, ITO) and small working areas, are widely utilized in organic photovoltaic fields. However, such a structure as well as conventional spin-coating method obviously restrict their industrial application. In this article, we report the deposition of silver nanowires(Ag NWs) on the flexible substrate by slot-die printing. The obtained Ag NWs films exhibited a high transmittance and a low resistance, and were further used as the transparent conductive electrode of OSCs. A typical conjugated polymer, poly[(2,5-bis(2-hexyldecyloxy)phenylene)-alt-(5,6-difluoro-4,7-di(thiophen-2-yl)benzo[c] [1,2,5]thiadiazole)](PPDT2FBT), was used as the active material to fabricate large-area(7 cm^2) solar cells by a slot-die coating process. The power conversion efficiency(PCE) could reach 1.87% initially and further increased to 3.04% by thermal annealing. Compared to the performance of reference cell on ITO substrate, the result indicated that the Ag NWs could be developed as an alternative substitute of conductive electrode to fabricate the large-area flexible OSCs by roll-to-roll printing. | Yi-fan Zhao Wen-jun Zou Huan Li 吕琨 延卫 魏志祥 | 2017 | Chinese Journal of Polymer Science2017，35，2： | 2 |
| 19 | Tunable flexible artificial synapses:a new path toward a wearable electronic system显示文摘The flexible electronics has been deemed to be a promising approach to the wearable electronic systems.However,the mismatching between the existing flexible deices and the conventional computing paradigm results an impasse in this field.In this work,a new way to access to this goal is proposed by combining flexible devices and the neuromorphic architecture together.To achieve that,a high-performance flexible artificial synapse is created based on a carefully designed and optimized memristive transistor.The device exhibits high-performance which has near-linear non-volatile resistance change under 10,000 identical pulse signals within the 515%dynamic range,and has the energy consumption as low as 45 fJ per pulse.It also displays multiple synaptic plasticity features,which demonstrates its potential for real-time online learning.Besides,the adaptability by virtue of its threeterminal structure specifically contributes its improved uniformity,repeatability,and reduced power consumption.This work offers a very viable solution for the future wearable computing. | Kunlong Yang Sijian Yuan Yuxiang Huan Jiao Wang Li Tu Jiawei Xu Zhuo Zou Yiqiang Zhan Lirong Zheng Fernando Seoane | 2018 | npj Flexible Electronics2018，2，1： | 1 |
| 20 | Identification of Novel Anaplastic Lymphoma Kinase (ALK) Inhibitors Using a Common Feature Pharmacophore Model Derived from Known Ligands Crystallized with ALK显示文摘 | Huan‐Zhang Xie Hai Lan You‐Li Pan Jun Zou Ze‐Rong Wang Lin‐Li Li Qi Huang Hui Zhang Sheng‐Yong Yang | 2012 | Chemical Biology & Drug Design2012，，2： | 1 |
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