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| 1 | Hemiballism-hemichorea induced by ketotic hyperglycemia: case report with PET study and review of the literature显示文摘Hemiballism-hemichorea(HB-HC)is commonly used to describe the basal ganglion dysfunction in non-ketotic hyperglycemic elderly patients.Here we report two elderly female patients with acute onset of involuntary movements induced by hyperglycemia with positive urine ketones.We described the computed tomography and magnetic resonance imaging findings in these two patients,which is similar to that of non-ketotic hyperglycemic HB-HC patients.FDG-PET was performed and the glucose metabolism in the corresponding lesion in these two patients was contradictory with each other.We tried to clarify the underlying mechanisms of HB-HC and explain the contradictory neuroradiological findings in FDG-PET as being performed at different clinical stages. | Yuyan Tan Xiaoyu Xin Qin Xiao Shengdi Chen Li Cao Huidong Tang | 2014 | Translational Neurodegeneration2014，3，1： | 21 |
| 2 | Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation显示文摘Haploidentical stem cell transplantation(haplo-SCT)achieves superior or at least comparable clinical outcomes to HLA-matched sibling donor transplantation(MSDT)in treating hematological malignancies.To define the underlying regulatory dynamics,we analyzed time courses of leukemia burden and immune abundance of haplo-SCT or MSDT from multiple dimension.First,we employed two nonirradiated leukemia mouse models which carried human AML-ETO or MLL-AF9 fusion gene to establish haplo-identical and major histocompatibility(MHC)-matched transplantation models and investigated the immune cell dynamic response during leukemia development in vivo.We found that haplo-matching the MHCs of leukemia cells with recipient mouse T cells prolonged leukemic mice survival and reduced leukemia burden.The stronger graft-versus-leukemia activity in haplo-SCT group mainly induced by decreased apoptosis and increased cytotoxic cytokine secretion including tumor necrosis factor–α,interferon-γ,pore-forming proteins and CD107a secreted by T cells or natural killer cells.Furthermore,we conducted a prospective clinical trial which enrolled 135 patients with t(8;21)acute myeloid leukemia that displayed minimal residual disease before transplantation and underwent either haplo-SCT or MSDT.The results showed that the haplo-SCT slowed the kinetics of the leukemia burden in vivo and reduced the cumulative incidence of relapse compared with MSDT.Ex vivo experiments showed that,1 year after transplantation,cytotoxic T lymphocytes from the haplo-SCT group had higher cytotoxicity than those from the MSDT group during the same period.Our results unraveled the role of immune cells in superior antileukemia effects of haplo-SCT compared with MSDT. | Huidong Guo Ying-Jun Chang Yan Hong Lan-Ping Xu Yu Wang Xiao-Hui Zhang Ming Wang Huan Chen Yu-Hong Chen Feng-Rong Wang Wei-Han Yu-Qian Sun Chen-Hua Yan Fei-Fei Tang Xiao-Dong Mo Kai-Yan Liu Xiao-Jun Huang | 2021 | Cellular & Molecular Immunology2021，18，5： | 11 |
| 3 | 显示文摘 | Tang Huidong Tan Shouhong Huang Zhengren | 2005 | Surface & Coatings Technology2005，197，： | 1 |
| 4 | PutMode: prediction of uncertain trajectories in moving objects databases显示文摘 | Shaojie Qiao Changjie Tang Huidong Jin Teng Long Shucheng Dai Yungchang Ku Michael Chau | 2010 | Applied Intelligence2010，，3： | 1 |
| 5 | Surface morphology of a-SiC coatings deposited by RF magnetron sputtering显示文摘 | Tang Huidong Tan Shouhong Huang Zhengren | 2005 | Surface & Coatings Technology2005，197，： | 1 |
| 6 | Mediator complex components are frequent targets for genetic alterations in various types of human cancer显示文摘The Mediator co-activator complex is a highly conserved,multisubunit protein complex required for gene transcription by RNA polymerase Ⅱ(RNAPⅡ)in all eukaryotes(Allen and Taatjes,2015).This complex,which consists of at least 30 polypeptides,can be divided into four structurally distinct sub-modules including the head,middle,tail,and cyclin-dependent kinase 8(CDK8) | Libin Deng Cheng Zhang Duling Miao Xiaoli Tang Shiwen Luo Hong-Bo Xin Huidong Shi | 2017 | Journal of Genetics and Genomics2017，44，12： | 0 |
| 7 | Seeking new,ultra-narrow-band blue emitting phosphors with high color purity for wide color gamut displays显示文摘Ultra-narrow-band phosphors have gained widespread applications in lighting and displays to enhance brightness and improve color saturation.Typical phosphor designs employ UCr_(4)C_(4)-type compounds and designing new narrow-band phosphors with high color purity is a major challenge.Here,we explored a Eu^(2+)-doped Ba_(5)GeO_(4)Br_(6)phosphor,showing a narrow-band blue emission(λ_(em)=436 nm) excitation at the near-ultraviolet light with a full width at half maximum of 30.7 nm and high color purity of 96.6%.In addition,attractive cathodoluminescence characteristics were systematically analyzed by varying filament current(30-70 mA) and accelerating voltage(3-7 eV).Robust anti-degradation behavior and color point stability under continuous electron beam bombardment were confirmed.Given its excellent performance in photoluminescence and cathodoluminescence,application in wide color gamut displays appears promising.Using commercial phosphors β-SiAlON:Eu^(2+)and K_(2)SiF6:Mn^(4+)as green and red light co nverte rs respectively,and the title phosphor as the blue light converters,the fabricated w-LED exhibits a wide color gamut of 82% NTSC. | Zuobin Tang Feng Du Zhihua Leng Huidong Xie Yanyan Li Lei Zhao | 2023 | Journal of Rare Earths2023，41，12： | 0 |
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