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| 1 | Colorectal cancer screening:The role of CT colonography显示文摘Computed tomography colonography(CTC) in colorectal cancer(CRC) screening has two roles:one present and the other potential.The present role is,without any further discussion,the integration into established screening programs as a replacement for barium enema in the case of incomplete colonoscopy.The potential role is the use of CTC as a first-line screening method together with Fecal Occult Blood Test,sigmoidoscopy and colonoscopy.However,despite the fact that CTC has been officially endorsed for CRC screening of average-risk individuals by different scientif ic societies including the American Cancer Society,the American College of Radiology,and the US Multisociety Task Force on Colorectal Cancer,other entities,such as the US Preventive Services Task Force,have considered the evidence insuff icient to justify its use as a mass screening method.Medicare has also recently denied reimbursement for CTC as a screening test.Nevertheless,multiple advantages exist for using CTC as a CRC screening test:high accuracy,full evaluation of the colon in virtually all patients,non-invasiveness,safety,patient comfort,detection of extracolonic findings and cost-effectiveness.The main potential drawback of a CTC screening is the exposure to ionizing radiation.However,this is not a major issue,since low-dose protocols are now routinely implemented,delivering a dose comparable or slightly superior to the annual radiation exposure of any individual.Indirect evidence exists that such a radiation exposure does not induce additional cancers. | Andrea Laghi Franco Iafrate Marco Rengo Cesare Hassan | 2010 | World Journal of Gastroenterology2010，16，32： | 6 |
| 2 | Perforation rate in CT colonography: a systematic review of the literature and meta-analysis显示文摘 | Davide Bellini Marco Rengo Carlo Nicola Cecco Franco Iafrate Cesare Hassan Andrea Laghi | 2014 | European Radiology2014，，7： | 2 |
| 3 | Activity of Crizotinib (PF02341066), a Dual Mesenchymal-Epithelial Transition (MET) and Anaplastic Lymphoma Kinase (ALK) Inhibitor, in a Non-small Cell Lung Cancer Patient with De Novo MET Amplification显示文摘 | Sai-Hong Ignatius Ou Eunice L. Kwak Christina Siwak-Tapp Joni Dy Kristin Bergethon Jeffrey W. Clark D. Ross Camidge Benjamin J. Solomon Robert G. Maki Yung-Jue Bang Dong-Wan Kim James Christensen Weiwei Tan Keith D. Wilner Ravi Salgia A. John Iafrate | 2011 | Journal of Thoracic Oncology2011，，5： | 2 |
| 4 | Electronic Energy Spectrum and the Concept of Capacitance in Quantum Dots显示文摘 | Macucci M Karl Hess Iafrate G J | 1993 | Phys Rev1993，48，17： | 1 |
| 5 | Detection of large-scale variation in the human genome 显示文摘 | Iafrate A J Feuk L Rivera M N | 2004 | Nature Genetics2004，36，9： | 1 |
| 6 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 7 | Orthotopic continent urinary diversion after radical cystectomy in pediatric patients with genitourinary rhabdomyosarcoma显示文摘 | Rigarnonti W Iafrate M Milani C | 2006 | J Urol2006，175，31： | 1 |
| 8 | Prostate biopsy:the transperineal approach显示文摘 | Galfano A Novara G Iafrate M | 2007 | EA-EBU Updates Series2007，5，： | 1 |
| 9 | Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: a success story to usher in the second decade of molecular targeted therapy in oncology显示文摘 | Ou S H Bartlett C H Mino-Kenudson M Cui J Iafrate A J | 2012 | Oncologist2012，17，： | 1 |
| 10 | 查看详情显示文摘 | Yu S G Kim K W Stroscio M A Iafrate G J Sun J P Hsddad G I | | 0，，： | 1 |
| 11 | Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to mlaplastic lymphoma kinase inhibitors 显示文摘 | McDermott U Iafrate A J Gray NS | 2008 | Cancer Res2008，68，9： | 1 |
| 12 | Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors显示文摘 | McDermott U Iafrate A J Gray NS | 2008 | Cancer Res2008，68，9： | 1 |
| 13 | 3D CT protocol in the assessment of the esophageal neoplastic lesions: can it improve TNM staging? 显示文摘 | Panebianeo V Grazhdani H Iafrate F | 2005 | Eur Radiol2005，16，2： | 1 |
| 14 | Detection of large-scale variation in the human genome显示文摘 | Iafrate A J Feuk L Rivera MN | 2004 | Nature genetics2004，36，9： | 1 |
| 15 | Copy number variations and clinical cytogenetic diagnosis of constitutional disorders显示文摘 | Lee C Iafrate AJ Brothman AR | 2007 | Nat Genet2007，39，： | 1 |
| 16 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 17 | Genomic alterations of aria- plastic lymphoma kinase may sensitize tumors to anaplastic lympho- ma kinase inhibitors 显示文摘 | McDermott U Iafrate A J Gray NS | 2008 | Cancer Res2008，68，： | 1 |
| 18 | Detection of large-s-cale variation in the human genome显示文摘 | A john Iafrate Lars Feuk Miguel N Rivera | 2004 | Nature Genet2004，36，： | 1 |
| 19 | Detection of large- scale variation in the human genome 显示文摘 | Iafrate AJ Feuk L Rivera MN | 2004 | Nat Genet2004，36，9： | 1 |
| 20 | Detection of large - scale variation in the human genome显示文摘 | Iafrate AJ Feuk L Rivera MN | 2004 | Nat Genet2004，36，： | 1 |
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