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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Eosinophilic ascites,an unusual presentation of eosinophilic gastroenteritis:A case report and review显示文摘Eosinophilic ascites(EA)is a rare disorder of unknown etiology that has been reported in both adult and pediatric patients.It is a part of the syndrome of eosinophilic gastroenteritis,which is characterized by eosinophilic infiltration of any or all layers of the gut wall and may involve any segment of the gastrointestinal tract.Peripheral eosinophilia may or may not be present.We report a case of EA that developed post partum. | Iryna S Hepburn Subbaramiah Sridhar Robert R Schade | 2010 | World Journal of Gastrointestinal Pathophysiology2010，1，5： | 22 |
| 3 | Metabolic inflammation as an instigator of fibrosis during nonalcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is characterized by excessive storage of fatty acids in the form of triglycerides in hepatocytes.It is most prevalent in western countries and includes a wide range of clinical and histopathological findings,namely from simple steatosis to steatohepatitis and fibrosis,which may lead to cirrhosis and hepatocellular cancer.The key event for the transition from steatosis to fibrosis is the activation of quiescent hepatic stellate cells(qHSC)and their differentiation to myofibroblasts.Pattern recognition receptors(PRRs),expressed by a plethora of immune cells,serve as essential components of the innate immune system whose function is to stimulate phagocytosis and mediate inflammation upon binding to them of various molecules released from damaged,apoptotic and necrotic cells.The activation of PRRs on hepatocytes,Kupffer cells,the resident macrophages of the liver,and other immune cells results in the production of proinflammatory cytokines and chemokines,as well as profibrotic factors in the liver microenvironment leading to qHSC activation and subsequent fibrogenesis.Thus,elucidation of the inflammatory pathways associated with the pathogenesis and progression of NAFLD may lead to a better understanding of its pathophysiology and new therapeutic approaches. | Angeliki Katsarou Ioannis I Moustakas Iryna Pyrina Panagiotis Lembessis Michael Koutsilieris Antonios Chatzigeorgiou | 2020 | World Journal of Gastroenterology2020，26，17： | 9 |
| 4 | Multitasking guardian of mitochondrial quality:Parkin function and Parkinson’s disease显示文摘The familial form of Parkinson's disease(PD)is linked to mutations in specific genes.The mutations in parkin are one of the most common causes of early-onset PD.Mitochondrial dysfunction is an emerging active player in the pathology of neurodegenerative diseases,because mitochondria are highly dynamic structures integrated with many cellular functions.Herein,we overview and discuss the role of the parkin protein product,Parkin E3 ubiquitin ligase,in the cellular processes related to mitochondrial function,and how parkin mutations can result in pathology in vitro and in vivo. | Iryna Kamienieva Jerzy Duszynski Joanna Szczepanowska | 2021 | Translational Neurodegeneration2021，10，1： | 3 |
| 5 | Electrochemical top-down synthesis of C-supported Pt nanoparticles with controllable shape and size:Mechanistic insights and application显示文摘In this work,we demonstrate the power of a simple top-down electrochemical erosion approach to obtain Pt nanoparticle with controlled shapes and sizes(in the range from-2 to-10 nm).Carbon supported nanoparticles with narrow size distributions have been synthesized by applying an alternating voltage to macroscopic bulk platinum structures,such as disks or wires.Without using any surfactants,the size and shape of the particles can be changed by adjusting simple parameters such as the applied potential,frequency and electrolyte composition.For instance,application of a sinusoidal AC voltage with lower frequencies results in cubic nanoparticles;whereas higher frequencies lead to predominantly spherical nanoparticles.On the other hand,the amplitude of the,sinusoidal signal was found to affect the particle size;the lower the amplitude of the applied AC signal,the smaller the resulting particle size.Pt/C catalysts prepared by this approach showed 0.76 A/mg mass activity towards the oxygen reduction reaction which is-2 times higher than the state-of-the-art commercial Pt/C catalyst(0.42 A/mg)from Tanaka.In addition to this,we discussed the mechanistic insights about the nanoparticle formation pathways. | Batyr Garlyyev Sebastian Watzele Johannes Fichtner Jan Michalicka Alexander Schokel Anatoliy Senyshyn Andrea Perego Dingjie Pan Hany A.El-Sayed Jan M.Macak Plamen Atanassov Iryna V.Zenyuk Aliaksandr S.Bandarenka | 2021 | Nano Research2021，14，8： | 2 |
| 6 | Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage显示文摘 | Steven Dooley Jafar Hamzavi Loredana Ciuclan Patricio Godoy Iryna Ilkavets Sabrina Ehnert Elke Ueberham Rolf Gebhardt Stephan Kanzler Andreas Geier Katja Breitkopf Honglei Weng Peter R. Mertens | 2008 | Gastroenterology2008，，2： | 2 |
| 7 | Glutathione-S-transferases genes-promising predictors of hepatic dysfunction显示文摘diseases pathogenesis are genes that encodes the synthesis of glutathione-Stransferase(GST),known as the second phase enzyme detoxification system that protects against endogenous oxidative stress and exogenous toxins,through catalisation of glutathione sulfuric groups conjugation and decontamination of lipid and deoxyribonucleic acid oxidation products.The group of GST enzymes consists of cytosolic,mitochondrial and microsomal fractions.Recently,eight classes of soluble cytoplasmic isoforms of GST enzymes are widely known:α-,ζ-,θ-,κ-,μ-,π-,σ-,andω-.The GSTs gene family in the Human Gene Nomenclature Committee,online database recorded over 20 functional genes.The level of GSTs expression is considered to be a crucial factor in determining the sensitivity of cells to a broad spectrum of toxins.Nevertheless,human GSTs genes have multiple and frequent polymorphisms that include the complete absence of the GSTM1 or the GSTT1 gene.Current review supports the position that genetic polymorphism of GST genes is involved in the pathogenesis of various liver diseases,particularly non-alcoholic fatty liver disease,hepatitis and liver cirrhosis of different etiology and hepatocellular carcinoma.Certain GST allelic variants were proven to be associated with susceptibility to hepatological pathology,and correlations with the natural course of the diseases were subsequently postulated. | Vasyl Prysyazhnyuk Larysa Sydorchuk Ruslan Sydorchuk Iryna Prysiazhniuk Kateryna Bobkovych Inna Buzdugan Valentina Dzuryak Petro Prysyazhnyuk | 2021 | World Journal of Hepatology2021，13，6： | 2 |
| 8 | Atherosclerosis and interferon-γ: New insights and therapeutic targets显示文摘 | Voloshyna Iryna Michael J. Littlefield Allison B. Reiss | 2013 | Trends in Cardiovascular Medicine2013，，： | 2 |
| 9 | On the change of periodicities in the Hicksian multiplier-accelerator model with a consumption floor显示文摘 | Tonu Puu Laura Gardini Iryna Sushko | 2006 | Chaos Solitons & Fractals2006，29，3： | 1 |
| 10 | Effect of delayed fruit harvest on photosynthesis, transpiration and nutrient remobilization of apple leaves显示文摘 | Iryna I T Michad M B | 2004 | New Phytologist2004，164，3： | 1 |
| 11 | DFT Study of Physisorption Effect of the Curcumin on CNT(8,0-6) Nanotube for Biological Applications显示文摘In the given work the adsorption properties of molecule curcumin((1 E,6 E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) on CNT(8,0-6) nanotube were investigated by the density functional theory(DFT) in the solvent water for the first time. The non-bonded interaction effects of compounds curcumin and CNT(8,0-6) nanotube on the electronic properties, UV/Vis spectra, chemical shift tensors and natural charges were determined and discussed. The electronic spectra of the compound curcumin and the complex CNT(8,0-6)/curcumin in the solvent water were calculated by time dependent density functional theory(TD-DFT) for investigation of the maximum wavelength value of molecule Curcumin before and after the non-bonded interaction with the CNT(8,0-6) nanotube and molecular orbitals involved in the formation of absorption spectrum of the complex CNT(8,0-6)/curcumin at maximum wavelength. | SIYAMAK Shahab MASOOME Sheikhi MEHRNOOSH Khaleghian IRYNA Balakhanava FATEMEH Azarakhshi | 2019 | Chinese Journal of Structural Chemistry2019，38，1： | 1 |
| 12 | Endophytie bacteria enhancing growth and disease resistance of potato ( Solanum tuberosum L) 显示文摘 | Pavlo Ardanov Leonid Oveharenko Iryna Zaets | 2011 | Biological Control2011，56，1： | 1 |
| 13 | Clinical and immunological characteristics of rheumatic diseases in children 显示文摘 | Iryna Chyzheuskaya Ludmial Belyaeva Helena Hrustaleva | 2014 | Pediatric Rheumatology2014，12，1： | 1 |
| 14 | Preclinical evaluation of adult stem cell engraftment and toxicity in the CNS of rhesus macaques显示文摘 | Iryna AI Kate B Jason D | 2006 | Mol Ther2006，13，6： | 1 |
| 15 | Development of the sorption-membrane “green” technology for boron removal from natural and wastewaters显示文摘 | Liudmyla Melnyk Vladyslav Goncharuk Iryna Butnyk Eugene Tsapiuk | 2007 | Desalination2007，205，： | 1 |
| 16 | Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage显示文摘 | Steven Dooley Jafar Hamzavi Loredana Ciuclan Patricio Godoy Iryna Ilkavets Sabrina Ehnert Elke Ueberham Rolf Gebhardt Stephan Kanzler Andreas Geier Katja Breitkopf Honglei Weng Peter R. Mertens | 2008 | Gastroenterology2008，，2： | 1 |
| 17 | Ca^2+ -induced apoptosis through CaN dephosphorylation of BAD显示文摘 | Wang H Pathan M Iryna M | 1999 | Science1999，284，5412： | 1 |
| 18 | What and where: 3D object recognition with accurate pose 显示文摘 | Iryna G David G L | 2006 | Toward Category-Level Object Recognition2006，30，12： | 1 |
| 19 | Altered neurogenesis in Alzheimer's disease显示文摘 | Iryna Ziabreva Elaine Perry Robert Perry | 2006 | J Psychosom Res2006，61，3： | 1 |
| 20 | Pregnancy-Associated Liver Disorders显示文摘 | Iryna S. Hepburn | 2008 | Digestive Diseases and Sciences2008，，9： | 1 |
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