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| 1 | Prevalence and predictors of hospitalization in Crohn's disease in a prospective population-based inception cohort from 2000-2012显示文摘AIM: To analyze the prevalence, length and predictors of hospitalization in the biological era in the populationbased inception cohort from Veszprem province.METHODS: Data of 331 incident Crohn's disease(CD) patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed(median age at diagnosis: 28; IQR: 21-40 years). Both in- and outpatient records were collected and comprehensively reviewed.RESULTS: Probabilities of first CD-related hospitalization and re-hospitalization were 32.3%, 45.5%,53.7% and 13.6%, 23.9%, 29.8%, respectively after one, three and five years of follow-up in Kaplan-Meier analysis. First-year hospitalizations were related to diagnostic procedures(37%), surgery or disease activity(27% and 21%). Non-inflammatory disease behavior at diagnosis(HR = 1.32, P = 0.001) and perianal disease(HR = 1.47, P = 0.04) were associated with time to first CD-related hospitalization, while disease behavior change(HR = 2.38, P = 0.002) and need for steroids(HR = 3.14, P = 0.003) were associated with time to first re-hospitalization in multivariate analyses.Early CD-related hospitalization(within the year of diagnosis) was independently associated with need for immunosuppressives(OR = 2.08, P = 0.001) and need for surgeries(OR = 7.25, P < 0.001) during the disease course.CONCLUSION: Hospitalization and re-hospitalization rates are still high in this cohort, especially during the first-year after the diagnosis. Non-inflammatory disease behavior at diagnosis was identified as the pivotal predictive factor of both hospitalization and rehospitalization. | Petra A Golovics Laszlo Lakatos Michael D Mandel Barbara D Lovasz Zsuzsanna Vegh Zsuzsanna Kurti Istvan Szita Lajos S Kiss Tunde Pandur Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，23： | 2 |
| 2 | Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease显示文摘 | Jiang Changtao Xie Cen Li Fei Zhang Limin Nichols Robert G Krausz Kristopher W Cai Jingwei Qi Yunpeng Fang Zhong-Ze Takahashi Shogo Tanaka Naoki Desai Dhimant Amin Shantu G Albert Istvan Patterson Andrew D Gonzalez Frank J | 2015 | Journal of Clinical Investigation2015，，1： | 1 |
| 3 | Electronic nose investigation of Alicyclobacillus acidoterrestris inoculated apple and orange juice treated by high hydrostatic pressure显示文摘 | Piroska H Istvan D Dietrich K | 2013 | Food Control2013，32，1： | 1 |
| 4 | Composite bioceramics in the system hydroxyapatite (fluorapatite)-yttria stabilized zirconia显示文摘 | Margrita D L Peter L Istvan S | 1995 | Adv Sci Technol1995，12，： | 1 |
| 5 | Composite bioceramics in the system hydroxyapatite (fluorapatite)-yttria stabilized zirconia显示文摘 | Margrita D L Peter L Istvan S | 1995 | Adv SciTechnol1995，12，： | 1 |
| 6 | Detection of phosphine : new aspects of the phosphorus cycle in the hydrosphere 显示文摘 | Istvan D Lajos F Ilona W | 1988 | Nature1988，333，26： | 1 |
| 7 | Effects of silymain (Legalon) treatment on the antioxidant deffence system and lipid peroxidation in patients with chronic alcoholic liver disease (a double-blind study)显示文摘 | GYORGY M GYORGY D ISTVAN L | 1990 | Orv Hetil1990，131，16： | 1 |
| 8 | The prevalence of atopic dermatitisin Oregon schoolchildren显示文摘 | Istvan JA Tofte SJ | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 9 | The prevalence of atopic dematitis in Oregon schoolchildren 显示文摘 | Laughter D Istvan JA Tofle S J | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 10 | Formation of volatile sulfur compounds in salt marsh sediment as influenced by soil redox condition显示文摘 | ISTVAN DEVAI DELAUNE R D | 1995 | Organic Geochemistry1995，23，4： | 1 |
| 11 | The prevalence of atopic dermatitis in Oregon schoolchildren显示文摘 | Laughter D Istvan JA Torte SJ | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 12 | The prevalence of atopic dermatitis in Oregon school children 显示文摘 | Laughter D Istvan JA Tofte SJ | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 13 | Geographical origin identification of pure Sri Lanka tea infusions with electronic nose,electronic tongue and sensory profile analysis显示文摘 | ZOLTAN K ISTVAN D LARINA L | | 0，，： | 1 |
| 14 | The prevalence ofatopic dermatitis in Oregon schoolchildren 显示文摘 | Laughter D Istvan JA Tofte SJ | 2000 | J Am AcadDermatol2000，43，4： | 1 |
| 15 | The prevalence of atopic dermatitis in Oregon school children显示文摘 | Laughter D Istvan JA Tofte SJ | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
| 16 | Geographical origin identification of pure Sri Lanka tea infusions with electronic nose,electronic tongue and sensory profile analysis显示文摘 | ZOLTAN K ISTVAN D LARINA L | | 0，，24： | 1 |
| 17 | Predictors of carpal tunnel syndrome: An l 1-year study of industrial workers 显示文摘 | Nathan P A Meadows K D Istvan J A | 2002 | J Hand Surg~2002，27，： | 1 |
| 18 | A leucine-zipper motif in photosystem I显示文摘 | Hans K?ssel Istvan D?ry Gabor Igloi Rainer Maier | 1990 | Plant Molecular Biology1990，，3： | 1 |
| 19 | The prevalence of atopic dermatitis in oregon schoolchildren显示文摘 | Laughter D Istvan JA Tofte S J | 2000 | J Am Acad Dermatol2000，43，： | 1 |
| 20 | The prevalence of atopic dermatitis in Oregon schoolchildren 显示文摘 | LAUGHTER D ISTVAN JA TOFTE SJ | 2000 | J Am Acad Dermatol2000，43，4： | 1 |
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