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| 1 | aunalysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza显示文摘 | Haibin Xu Jingyuan Song Hongmei Luo Yujun Zhang Qiushi Li Yingjie Zhu Jiang Xu Ying Li Chi Song Bo Wang Wei Sun Guoan Shen Xin Zhang Jun Qian Aijia Ji Zhichao Xu Xiang Luo Liu He Chuyuan Li Chao Sun Haixia Yah Guanghong Cui Xiwen Li Xian 'en Li Jianhe Wei Juyan Liu Yitao Wang Alice Hayward David Nelson Zemin Ning Reuben J. Peters Xiaoquan Qi Shilin Chen | 2016 | Molecular Plant2016，9，6： | 70 |
| 2 | High-throughput Binary Vectors for Plant Gene Function Analysis显示文摘一系列高产量的二进制克隆向量被构造在高等植物便于基因函数分析。这个向量系列为蛋白质本地化为工厂表示,倡导者分析,基因 silencing 和绿荧光灯的蛋白质熔化由 plasmidsdesigned 组成了。这些向量为 lambda 噬菌体 integrase/excisionase 提供了高产量、有效的克隆的利用地点。另外,我们在多重克隆再并入的唯一的限制地点地点和启用的倡导者代替。全部向量系列与完全的顺序信息是可得到的并且详细说明注解并且自由地为非商业性的使用被散布到科学界…… | Zhi-Yong Lei Ping Zhao Min-Jie Cao Rong Cui Xi Chen Li-Zhong Xiong Qi-Fa Zhang David J. Oliver Cheng-Bin Xiang | 2007 | Journal of Integrative Plant Biology2007，49，4： | 8 |
| 3 | Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death显示文摘 | Lifeng Yuan Linhui Zhai Lili Qian De Huang Yi Ding Handan Xiang Xiaojing Liu J. Will Thompson Juan Liu Yong-Han He Xiao-Qiong Chen Jing Hu Qing-Peng Kong Minjia Tan Xiao-Fan Wang | 2018 | Cell Research2018，28，6： | 7 |
| 4 | Construction of a Plant Transformation-ready Expression cDNA Library for Thellungiella halophila Using Recombination Cloning显示文摘盐十字花科植物(Thellungiella halophila ) ,模型的近亲种 Arabidopsis thaliana L. ,是被使适应严厉盐的环境的 extremophile。到我的从这种的咸忍耐的基因,我们从对待与的盐十字花科植物工厂构造了一个入口 cDNA 图书馆由使用修改 cDNA 合成和完全没有操作正在包含限制酶和脱氧核糖核酸连接酶的一个改进帮助再结合的 cDNA 图书馆构造方法咸压力。这个 cDNA 图书馆构造过程显著地被简化, cDNA 图书馆的质量被改进。这个入口 cDNA 图书馆是随后,进目的地二进制代码向量 pCB406 的 shuttled 经由帮助再结合的克隆为工厂转变和表示设计了。图书馆是准备好了的工厂转变并且被用来在大规模上转变 Arabidopsis 以便为功能的基因采矿创造转基因的线的一个大集合。 | Wan-Song Ni Zhi-Yong Lei Xi Chen David J. Oliver Cheng-Bin Xiang | 2007 | Journal of Integrative Plant Biology2007，49，9： | 6 |
| 5 | The Virtual Geoscience Workbench, VGW: Open Source tools for discontinuous systems显示文摘In 1989 work began on merging finite and discrete elements. During 1990 algorithmic solutions for the new combined method were developed, together with a C-based implementation known as the Y code. In 2004 these developments and implementations were published as a textbook. Queen Mary University of London (QMUL) and Imperial College are currently engaged in a research project to make Y codes in both 2D and 3D available in Open Source format and with mainly geoscience problems in mind. The result is a set of Open Source tools for Geoscience (VGW), key components of which are summarised in this paper, together with illustrative range of simulation results. | A. Munjiza J. Xiang X. Garcia J.P. Latham G.G. Schiava D'Albano N.W.M. John | 2010 | Particuology2010，8，2： | 4 |
| 6 | Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities显示文摘 | W. P. Jia C. Pang L. Chen Y. Q. Bao J. X. Lu H. J. Lu J. L. Tang Y. M. Wu Y. H. Zuo S. Y. Jiang K. S. Xiang | 2007 | Diabetologia2007，，2： | 4 |
| 7 | Severe human infection with a novel avian-origin influenza A(H7N4) virus显示文摘Human infections with influenza H7 subtypes, such as H7N9, have raised concerns worldwide. Here, we report a human infection with a novel influenza A(H7N4) virus. A 68 years-old woman with cardiovascular and cholecystic comorbidities developed rapidly progressed pneumonia with influenza-like-illness as initial symptom, recovered after 23 days-hospitalization including 8 days in ICU. Laboratory indicators for liver and blood coagulation dysfunction were observed. Oseltamivir phosphate, glucocorticoids and antibiotics were jointly implemented, with nasal catheterization of oxygen inhalation for this patient.We obtained the medical records and collected serial respiratory and blood specimens from her. We collected throat, cloacal and/or feces samples of poultry and wild birds from the patient's backyard, neighborhood, local live poultry markets(LPMs) and the nearest lake. All close contacts of the patient were followed up and sampled with throat swabs and sera. Influenza viruses and other respiratory pathogens were tested by real-time RT-PCR, viral culturing and/or sequencing for human respiratory and bird samples. Micro-neutralizing assay was performed for sera. A novel reassortant wild bird-origin H7N4 virus is identified from the patient and her backyard poultry(chickens and ducks) by sequencing, which is distinct from previously-reported avian H7N4 and H7N9 viruses. At least four folds increase of neutralizing antibodies to H7N4 was detected in her convalescent sera. No samples from close contacts, wild birds or other poultry were tested positive for H7N4 by real-time RT-PCR. | Xiang Huo Lun-biao Cui Cong Chen Dayan Wang Xian Qi Ming-hao Zhou Xiling Guo Fengming Wang William J. Liu Weirong Kong Daxin Ni Ying Chi Yiyue Ge Haodi Huang Feifei Hu Chao Li Xiang Zhao Ruiqi Ren Chang-jun Bao George F. Gao Feng-Cai Zhu | 2018 | Science Bulletin2018，63，16： | 4 |
| 8 | Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome显示文摘 | Delphine M. Saulnier Kevin Riehle Toni–Ann Mistretta Maria–Alejandra Diaz Debasmita Mandal Sabeen Raza Erica M. Weidler Xiang Qin Cristian Coarfa Aleksandar Milosavljevic Joseph F. Petrosino Sarah Highlander Richard Gibbs Susan V. Lynch Robert J. Shulman | 2011 | Gastroenterology2011，，5： | 4 |
| 9 | Estimating organic carbon storage in temperate wetland profiles in Northeast China显示文摘 | Wen-Ju Zhang He-Ai Xiao Cheng-Li Tong Yi-Rong Su Wan-sheng Xiang Dao-You Huang J. Keith Syers Jinshui Wu | 2008 | Geoderma2008，，1： | 2 |
| 10 | microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells显示文摘 | Elena Vigorito Kerry L. Perks Cei Abreu-Goodger Sam Bunting Zou Xiang Susan Kohlhaas Partha P. Das Eric A. Miska Antony Rodriguez Allan Bradley Kenneth G.C. Smith Cristina Rada Anton J. Enright Kai-Michael Toellner Ian C.M. MacLennan Martin Turner | 2007 | Immunity2007，，6： | 2 |
| 11 | NF-E2:a Novel Regulator of Alpha-hemoglobin Stabilizing Protein Gene Expression显示文摘Objective To investigate whether α-hemoglobin stabilizing protein (AHSP), the α-globin-specific molecular chaperone, is regulated by erythroid transcription factor NF-E2. Methods We established the stable cell line with NF-E2p45 (the larger subunit of NF-E2) short hairpin RNA to silence its expression. Western blot, real-time polymerase chain reaction, and chromatin immunoprecipitation (ChIP) analysis were performed to detect the expression of AHSP, the histone modifications at AHSP gene locus, and the binding of GATA-1 at the AHSP promoter with NF-E2p45 deficiency. ChIP was also carried out in dimethyl sulfoxide (DMSO)-induced DS19 cells and estrogen-induced G1E-ER4 cells to examine NF-E2 binding to the AHSP gene locus and its changes during cell erythroid differentiation. Finally, luciferase assay was applied in HeLa cells transfected with AHSP promoter fragments to examine AHSP promoter activity in the presence of exogenous NF-E2p45. Results We found that AHSP expression was highly dependent on NF-E2p45. NF-E2 bound to the regions across AHSP gene locus in vivo, and the transcription of AHSP was transactivated by exogenous NF-E2p45. In addition, we observed the decrease of H3K4 trimethylation and GATA-1 occupancy at the AHSP gene locus in NF-E2p45-deficient cells. Restoration of GATA-1 in G1E-ER4 cells in turn led to increased DNA binding of NF-E2p45. Conclusion NF-E2 may play an important role in AHSP gene regulation, providing new insights into the molecular mechanisms underlying the erythroid-specific expression of AHSP as well as new possibilities for β-thalassemia treatment. | Guo-wei Zhao Rui-feng Yang Xiang Lu Mitchell J. Weiss De-pei Liu Chih-chuan Liang | 2010 | Chinese Medical Sciences Journal2010，25，4： | 2 |
| 12 | Analysis of Gene Expression Patterns during Seed Coat Development in Arabidopsis显示文摘种子上衣为胚胎保护,种子水和,和疏开是重要的。种子上衣作文也农业部门感兴趣,自从它同样地为人和家畜影响营养的价值。尽管一些种子上衣基因被识别了,控制种子上衣开发的发展小径完全没被阐明,并且一个全球基因程序与种子上衣开发联系了没被报导。这研究使用联合基因并且 genomic 在 Arabidopsis thaliana 来临开始到地址这些知识差距。种子上衣开发是小卵的覆盖物区分进专业化房间类型的一个复杂过程。在 Arabidopsis,房间的最外面的层分泌粘液进 apoplast 并且开发作为小柱知道的一面第二等的房间墙。在外皮下面的层,栅,综合它的内部正切的方面上的一面第二等的房间墙。最深处的层(pigmented 层或内皮细胞层) 生产 proanthocyanidins 压缩进丹宁并且氧化,给一种棕色的颜色成熟播种。这些房间层的基因分离用 ap2-7 和 tt16-1 异种被完成,在外皮 / 栅和内皮细胞层不分别地发展的地方。这基因脱离被利用由在开发期间在关键转变孤立并且收集并且执行全球基因表达式分析种子上衣检验这些房间类型的发展程序。数据显示外皮和 pigmented 层的发展节目独立地相对继续。能被用于种子上衣开发的新基因候选人的鉴定的全球表达式数据集被产生。这些数据集为在 Arabidopsis 开发种子上衣提供全面表达式侧面,并且应该为另外的种子系统提供一个有用资源和引用。 | Gillian Dean YongGuo Cao DaoQuan Xiang Nicholas J. Provart Larissa Ramsay Abdul Ahad Rick White Gopalan Selvaraj Raju Datla George Haughn | 2011 | Molecular Plant2011，4，6： | 2 |
| 13 | Human pancreatic Beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13显示文摘 | S. Nishi M. Stoffel K. Xiang T. B. Shows G. I. Bell J. Takeda | 1992 | Diabetologia1992，，8： | 2 |
| 14 | Functional analysis of a novel male fertility CYP86MF gene in Chinese cabbage (Brassica campestris L. ssp. chinensis makino)显示文摘 | J. S. Cao X. L. Yu W. Z. Ye G. Lu X. Xiang | 2006 | Plant Cell Reports2006，，12： | 1 |
| 15 | The sequence of precipitation in the Al-Mg-Si-Cu alloy AA6111显示文摘 | Xiang Wang Shahrzad Esmaeili David J. Lloyd | 2006 | Metallurgical and Materials Transactions A2006，，9： | 1 |
| 16 | Influence of Ambient Temperature on Nanosecond and Picosecond Laser-Induced Bulk Damage of Fused Silica显示文摘 | L. Yang X. D. Yuan H. X. Deng X. Xiang W. G. Zheng S. B. He Y. Jiang H. B. Lv L. Ye H. J. Wang X. T. Zu Haiyan Xiao | 2014 | Advances in Condensed Matter Physics2014，，： | 1 |
| 17 | Unbalanced expression of protease-activated receptors-1 and -2 in the colon of diarrhea-predominant irritable bowel syndrome patients显示文摘 | Zhao Xiang Bian Zhi Li Zhi Xin Huang Man Zhang Hong Li Chen Hong Xi Xu Joseph J. Y. Sung | 2009 | Journal of Gastroenterology2009，，7： | 1 |
| 18 | The asymptotic stability of one-parameter methods for neutral differential equations显示文摘 | J. X. Kuang J. X. Xiang H. J. Tian | 1994 | BIT1994，，3： | 1 |
| 19 | microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells显示文摘 | Elena Vigorito Kerry L. Perks Cei Abreu-Goodger Sam Bunting Zou Xiang Susan Kohlhaas Partha P. Das Eric A. Miska Antony Rodriguez Allan Bradley Kenneth G.C. Smith Cristina Rada Anton J. Enright Kai-Michael Toellner Ian C.M. MacLennan Martin Turner | 2007 | Immunity2007，，6： | 1 |
| 20 | Tannin Dynamics of Propagules and Leaves of Kandelia candel and Bruguiera gymnorrhiza in the Jiulong River Estuary, Fujian, China显示文摘 | Y. M. Lin J. W. Liu P. Xiang P. Lin G. F. Ye L. S. L. Sternberg | 2006 | Biogeochemistry2006，，3： | 1 |
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