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| 1 | Synthesis, DNA-binding and photocleavage studies of ruthenium(Ⅱ) complexes [Ru(btz)_3]^(2+) and [Ru(btz)(dppz)_2]^(2+)显示文摘Two new ruthenium(Ⅱ) complexes, [Ru(btz)3](ClO4)2 (1) and [Ru(btz)(dppz)2](ClO4)2 (2) (btz = 4,4′-bithi-azole, dppz = dipyrido[3,2-a:2′,3′-c]phenazine), have been synthesized and characterized by elemental analysis, 1H NMR, ES-MS and X-ray crystallography. The DNA binding behaviors of two complexes have been studied by spectroscopic and viscosity measurements. The results suggest that complex 1 binds to CT-DNA via an electrostatic mode, while complex 2 via an intercalative mode. Under irradiation at 365 nm, both complexes were found to promote the cleavage of plasmid pBR 322 DNA from supercoiled form Ⅰ to nicked form Ⅱ. The mechanism studies reveal that singlet oxygen 1O2 and hydroxyl radical (OH-) play a significant role in the photocleavage process. | YU HuiJuan, HUANG ShuMei, KOU JunFeng, LI LvYing, JIA HaiNa, CHAO Hui & JI LiangNian MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China | 2009 | Science China Chemistry2009，52，9： | 4 |
| 2 | DNA Binding and Oxidative Cleavage by a Water-soluble Carboxyl Manganese(Ⅲ) Corrole显示文摘小牛胸腺 DNA (CT DNA ) 和水溶性的锰 corrole 的相互作用, 5,10,15-tris (4-carboxyphenyl ) corrolatomanganese (III )(MnIIITCPC ) 被吸收系列,荧光系列和 CD 系列,以及由粘性大小学习了。结果表明这锰 corrole 与 4.67 敲 ? 景的内在的有约束力的经常的 Kb 经由一个外面的沟绑定模式把 DNA 绑在 CT 吗? | Yang Zhang Qi Wang Jinyan Wen Xiangli Wang Mian HR Mahmood Liangnian Ji Haiyang Liu | 2013 | Chinese Journal of Chemistry2013，31，10： | 3 |
| 3 | Progress in study on metalloporphyrin mimicking metalloenzymes显示文摘The development of research on metalloporphyrins, which are used as model compounds for some metalloenzymes, is reviewed, including the survey of oxygen binding of heme, the catalytic oxidation of cytochrome P450, the molecular recognition to amino acid esters, the self-assembly and self-aggregation of metalloporphyrins. | JI Liangnian , PENG Xiaobin and HUANG Jinwang( Department of Chemistry, Zhongshan University, Guangzhou 510275,China Department of Applied Chemistry, South China University of Technology, Guangzhou 510641, China) | 2002 | Progress in Natural Science:Materials International2002，12，5： | 2 |
| 4 | Metalloporphyrin-catalited hydroxylation of cyclohexane with moleculer oxygen显示文摘 | Ji Liangnian Liu Min Hsieh Ankong | 1991 | Mol catal1991，70，： | 1 |
| 5 | Synthesis,crystal structures,electrochemical and spectroscopic properties of ruthenium(Ⅱ) complexes containing diamino-1,3,5-triazine derivatives显示文摘Three Ru(Ⅱ) complexes [Ru(bpy)2(1-IQTNH)](ClO4)2 (1), [Ru(bpy)2(2-QTNH)](ClO4)2 (2) and [Ru(bpy)2(3-IQTNH)](ClO4)2 (3) (bpy = 2,2′-bipyridine, 1-IQTNH = 6-(isoquinolin-1-yl)-1,3,5-triazine-2,4-diamine, 2-QTNH = 6-(quinolin-2-yl)-1,3,5-triazine-2,4-diamine, 3-IQTNH = 6-(isoquinolin-3-yl)-1,3,5-triazine-2,4-diamine) have been synthesized and characterized by elemental analysis, 1H NMR spectroscopy, electrospray ionization mass spectrometry and X-ray crystallography. The electrochemical and spectroscopic properties of the complexes differ from those of [Ru(bpy)3]2+ owing to the structural differences between the ligands and their complexes. | CHEN Yu, XU WenChao, KOU JunFeng, WEI XuHui, YU BoLe, CHAO Hui & JI LiangNian MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China | 2010 | Science China Chemistry2010，53，10： | 1 |
| 6 | Shape and enantioselective interaetion of Ru(Ⅱ)/Co(Ⅲ)polypyridyl complexes with DNA显示文摘 | Ji Liangnian Zou Xiaohua Liu Jingang | 2010 | Coord Chem Res2010，32，36： | 1 |
| 7 | The production of glucose oxidase using the waste myceliums of Aspergillus niger and the effects of metal ions on the activity of glucose oxidase显示文摘 | Tongbu Lu Xinyu Peng Huiying Yang Liangnian Ji | 1996 | Enzyme and Microbial Technology1996，，5： | 1 |
| 8 | Study of transient luminescence of three kinds of Ru complexes bound to DNA显示文摘The transient luminescence of three kinds of ruthenium complexes [Ru(bpy)2(7-CH3-dppz)]2+, [Ru(bpy)2(7-F-dppz)]2+ and [Ru(phen)2(7-F-dppz)]2+ bound to calf thy-mus DNA (ctDNA) has been studied by using the time-resolved spectroscopy. The results show that the luminescence is due to the radiative decay from the charge-transfer states to the ground state. By the interaction with DNA, the radia-tiveless rate of the photoexcited Ru complex molecules decreases, which results in the increase of luminescence lifetime and efficiency. The structure of the Ru com-plex has an important impact on the interaction with DNA. The [Ru(bpy)2(7-CH3-dppz)]2+ shows the longest luminescence lifetime (about 382 ns), while the [Ru(bpy)2(7-F-dppz)]2+ shows the shortest lifetime (about 65 ns). The possible origin of the luminescence dynamics is discussed. | ZHU WeiLing LIU XueWen WANG Hui YU HuiJuan LI AiZheng CHAO Hui ZHENG KangCheng JI LiangNian | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，2： | 1 |
| 9 | Photodynamic Therapy Activities of 10-(4-Formylphenyl)-5,15-bis(pentafluorophenyl)corrole and Its Gallium Complex显示文摘10-(4-Formylphenyl )-5,15-bis(pentafluorophenyl)corrole 1 并且它的镓建筑群 1-Ga 被用来在肝癌症(BEL-7402 ) 调查他们的 photocytotoxicity,肺癌症(A549 ) 和颈的癌症(Siha, Hela ) 房间线。在所有测试肿瘤房间之中, Siha 肿瘤房间对光力学的治疗(太平洋夏季时间) 最敏感在 1 的治疗和 1-Ga。1 的太平洋夏季时间 IC 50 和向 Siha 肿瘤房间的 1-Ga 分别地到达 1.3 和 0.8 µmol/L,它比 cisplatin 的高是 10 褶层。1 并且没有搬运人蛋白质的帮助, 1-Ga 可能顺利越过肿瘤房间膜过去,并且在肿瘤的细胞质主要局部性房间。在太平洋夏季时间治疗以后,增加的细胞内部的反应的氧种类(ROS ) 水平和 mitochondrial 膜潜力显著地减少了,它将最后导致肿瘤房间的 apoptosis。 | Fan Cheng Liting Huang Huahua Wang Yunjun Liu Jaipal Kandhadi Hui Wang Liangnian Ji Haiyang Liu | 2017 | Chinese Journal of Chemistry2017，35，1： | 1 |
| 10 | DNA Binding Properties and Cytotoxic Activities of Two Trinuclear Ruthenium(Ⅱ) Polypyridyl Complexes显示文摘 | XU Li CHEN Yu WEI Hui WU Wenshan LI Zhongzhi LIN Yiwei CHAO Hui JI Liangnian | 2014 | Chemical Research in Chinese Universities2014，30，3： | 0 |
| 11 | The self-aggregation of chiral threonine-linked porphyrins and their zinc( II) complexes显示文摘The self-aggregation of chiral threonine-linked porphyrins and their zinc(Ⅱ) complexes in water-alcohol system and water-alcohol-NaCI system has been studied by circular dichroism (CD), UV-Vis absorption spectra and fluorescence spectra methods. The experiment results indicate that chiral threonine-linked porphyrins and their zinc(Ⅱ) complexes have two different kinds of aggregates in water-alcohol system and water-alcohol-NaCI system. And the porphyrins may form highly organized and orientated aggregates in water-alcohol-NaCI system. The aggregates in water-alcohol-NaCI system may have helical structures. | Xiaobin Peng Jinwang Huang Liangnian Ji | 2000 | Chinese Science Bulletin2000，45，5： | 0 |
| 12 | Synthesis of a new iron(Ⅲ) porphyrin acrylate-styrene copolymer and its catalysis for hydroxylation of cyclohexane显示文摘A new iron(III)porphyrin acrylate-styrene copo-lymer,P[(PorFe)A-S],was synthesized by the reaction of iron(III)porphyrin acrylate with styrene and characterized by UV-Vis,Infrared spectra(IR),inductively coupled plasma-atomic emission spectrometry(ICP)and molecular weight determination.Its catalytic activity in the hydroxylation of cyclohexane for model cytochrome P450 in the P[(PorFe)A-S]-O_(2)–ascrobate-thiosalicylic acid system has been studied.It was found that the P[(PorFe)A-S]has a higher catalytic activity than non-supported iron(III)porphyrin and its high catalytic activity remained in reuse.The catalytic activity of P[(PorFe)A-S]was discussed in the view of the microenvi-ronment of iron(III)porphyrin.It is proposed that the cata-lytic activity of the P[(PorFe)A-S]may be further enhanced by construction of a homophase catalytic system containing the iron(III)porphyrin acrylate-styrene copolymer. | YU Hancheng CHEN Xianli LI Xixian HUANG Jinwang JI Liangnian | 2007 | Frontiers of Chemical Science and Engineering2007，1，1： | 0 |
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