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| 1 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 2 | Stochastic processes in renewable power systems: From frequency domain to time domain显示文摘With the increasing penetration of renewable energy resources(RESs), the uncertainties of volatile renewable generations significantly affect the power system operation. Such uncertainties are usually modeled as stochastic variables obeying specific distributions by neglecting the temporal correlations. Conventional approaches to hedge the negative effects caused by such uncertainties are thus hard to pursue a trade-off between computation efficiency and optimality. As an alternative, the theory of stochastic process can naturally model temporal correlation in closed forms. Attracted by this feature, our research group has been conducting thorough researches in the past decade to introduce stochastic processes within renewable power systems. This paper summarizes our works from the perspective of both the frequency domain and the time domain, provides the tools for the analysis and control of power systems under a unified framework of stochastic processes, and discusses the underlying reasons that stochastic process-based approaches can perform better than conventional approaches on both computational efficiency and optimality. These work may shed a new light on the research of analysis, control and operation of renewable power systems.Finally, this paper outlooks the theoretic developments of stochastic processes in future’s renewable power systems. | SONG YongHua CHEN XiaoShuang LIN Jin LIU Feng QIU YiWei | 2019 | Science China(Technological Sciences)2019，62，12： | 4 |
| 3 | Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma:an exploratory study显示文摘Background:Previous studies have shown that macrophage migration inhibitory factor(MIF)is involved in the pathogenesis of asthma.This study aimed to investigate whether serum MIF reflects a therapeutic response in allergic asthma.Methods:We enrolled 30 asthmatic patients with mild-to-moderate exacerbations and 20 healthy controls,analyzing the parameter levels of serum MIF,serum total immunoglobulin E(tIgE),peripheral blood eosinophil percentage(EOS%),and fractional exhaled nitric oxide(FeNO).Lung function indices were used to identify disease severity and therapeutic response.Results:Our study showed that all measured parameters in patients were at higher levels than those of controls.After one week of treatment,most parameter levels decreased significantly except for serum tIgE.Furthermore,we found that serum MIF positively correlated with EOS%as well as FeNO,but negatively correlated with lung function indices.Receiver operator characteristic(ROC)curve analysis indicated that among the parameters,serum MIF exhibited a higher capacity to evaluate therapeutic response.The area under the curve(AUC)of MIF was 0.931,with a sensitivity of 0.967 and a specificity of 0.800.Conclusions:Our results suggested that serum MIF may serve as a potential biomarker for evaluating therapeutic response in allergic asthma with mild-to-moderate exacerbations. | Huiyuan ZHU Shaochun YAN Jingshuo WU Zhong ZHANG Xiaolin LI Zheng LIU Xing MA Lina ZHOU Lin ZHANG Mingming FENG Yiwei GENG Aixin ZHANG Sabina JANCIAUSKIENE Aiguo XU | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，6： | 3 |
| 4 | Confined Ni-In intermetallic alloy nanocatalyst with excellent coking resistance for methane dry reforming显示文摘Carbon dioxide and methane are two main greenhouse gases which are contributed to serious global warming.Fortunately,dry reforming of methane(DRM),a very important reaction developed decades ago,can convert these two major greenhouse gases into value-added syngas or hydrogen.The main problem retarding its industrialization is the seriously coking formation upon the nickel-based catalysts.Herein,a series of confined indium-nickel(In-Ni)intermetallic alloy nanocatalysts(In_(x)Ni@SiO_(2))have been prepared and displayed superior coking resistance for DRM reaction.The sample containing 0.5 wt.%of In loading(In_(0.5)Ni@SiO_(2))shows the best balance of carbon deposition resistance and DRM reactivity even after 430 h long term stability test.The boosted carbon resistance can be ascribed to the confinement of core–shell structure and to the transfer of electrons from Indium to Nickel in In-Ni intermetallic alloys due to the smaller electronegativity of In.Both the silica shell and the increase of electron cloud density on metallic Ni can weaken the ability of Ni to activate C–H bond and decrease the deep cracking process of methane.The reaction over the confined InNi intermetallic alloy nanocatalyst was conformed to the Langmuir-Hinshelwood(L-H)mechanism revealed by in situ diffuse reflectance infrared Fourier transform spectroscopy(in-situ DRIFTS).This work provides a guidance to design high performance coking resistance catalysts for methane dry reforming to efficiently utilize these two main greenhouse gases. | Wenming Liu Le Li Sixue Lin Yiwei Luo Zhenghong Bao Yiru Mao Kongzhai Li Daishe Wu Honggen Peng | 2022 | Journal of Energy Chemistry2022，31，2： | 3 |
| 5 | Fe3O4 Octahedral Colloidal Crystals显示文摘我们在场为没有底层的帮助的高度命令的八面的 Fe3O4 胶体的单个晶体的大规模制造的一个灵巧、可控制的方法。油的酸被用来在胶体的答案减少 nano 大楼块的溶解度并且导致一个结晶化过程。我们的胶体的晶体具有 multimicron 尺寸并且显示出典型结晶的特征。他们有很柔韧的结构并且当一篇小说与相对狭窄的毛孔尺寸分布订了磁性的 mesoporous 材料,能服务。样品基于它的好 crystallinity,以及 interparticle 在 5 K 拥有 100 K 的极其高的 Verwey 转变温度(T V ) 和 86 emu/g 的高浸透磁化(M S ) 偶极的相互作用行为从它的唯一的结构产生。电气化学的大小表明了 mesoporous 的优秀能力胶体的晶体当在锂离子电池使用了时。 | L-r Meng Weimeng Chen Yiwei Tan Lin Zou Chinping Chen Heping Zhou Qing Peng Yadong Li | 2011 | Nano Research2011，4，4： | 3 |
| 6 | Clinical study of transcatheter occlusion in treating ventricular septal defect combined with right coronary cusp bulge显示文摘Background: Perimembranous ventricular septal defect combined with right coronary cusp bulge generally should be treated with surgical thoracotomy, owing to the potential aortic regurgitation. However, the minimally invasive method of transcatheter closure has always attracted the attention of cardiologists and patients. The present study aimed to apply transcatheter occlusion in treating ventricular septal defect with right coronary cusp bulge and further evaluate the clinical effect through follow-up. Materials and methods: A total of 40 children diagnosed as having a ventricular septal defect with right coronary cusp bulge, examined using transthoracic echocardiography and cardiovascular angiography, were enrolled in this study. The ventricular septal defects were closed by placing occluders through transcatheter occlusion treatment. During the operation process, the children underwent angiography and transthoracic echocardiography examinations to check the position of the occlude and the extent of aortic regurgitation. The influence of occlusion on the conduction system was evaluated using a surface electrocardiogram. The children were followed up after their procedures. Results: All 40 patients were immediately and successfully occluded. Three patients with filament residual shunts were observed during the operations. No major surgical complications occurred during the perioperative period. During the follow-up period, the positions of all the occluders were good, the residual shunts in the three patients disappeared, and no new or aggravated aortic regurgitation occurred. Electrocardiogram did not reveal any atrioventricular blocks. Only one patient suffered from an incomplete right bundle branch block. Conclusions: Children diagnosed with ventricular septal defect combined with right coronary cusp bulge could be considered for transcatheter occlusion. With appropriate indications and methods, the effect may be favorable. | Wei Ji Zhifang Zhang Wenchuo Zhao Jie Shen Lijun Fu Lin Shi Yiwei Chen Fen Li | 2018 | Journal of Interventional Medicine2018，1，4： | 3 |
| 7 | Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells显示文摘 | Yiwei Lin Jian Wu Hong Chen Yeqing Mao Yunfu Liu Qiqi Mao Kai Yang Xiangyi Zheng Liping Xie | 2012 | FEBS Letters2012，，4： | 2 |
| 8 | BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells显示文摘在 oncogene BRAF (V600E ) 的变化在 ~ 被发现 10% colorectal 癌症(CRC ) 并且与穷人被联系预后。然而, BRAF (V600E ) 有有限回答到小分子的药, vemurafenib,一个 BRAF 禁止者,和 BRAF 抑制被认为引起反馈 EGFR 发信号的激活支持继续增长。在这研究,我们探索了 dabrafenib,一个 BRAF 禁止者,和 cetuximab 的联合使用的效果,一个 EGFR 禁止者,在 BRAF (V600E ) 上变异的 CRC 干细胞和它的可能的机制。通过房间生存能力分析,流动 cytometry,形成的范围,和西方的污点分析,我们发现 dabrafenib 与 cetuximab 装 synergize 减少房间生存能力,导致提高的 apoptotic 率和房间周期在 BRAF (V600E ) 的拘捕变异的 HT-29 房间并且禁止干细胞能力。进一步,西方的污点分析表明那条 PTEN/Src/c-Myc 小径可能涉及在 dabrafenib 和 cetuximab 之间的协同。总的来说,我们的学习证明 dabrafenib 和 cetuximab 的联合在 BRAF (V600E ) 导致增加的 antitumor 活动和减少的干细胞能力变异的 CRC 房间。 | Zhenhua Wu Mingzhu Huang Yiwei Gong Chen Lin Weijian Guo | 2018 | Acta Biochimica et Biophysica Sinica2018，50，4： | 2 |
| 9 | Kilometers Long Graphene-Coated Optical Fibers for Fast Thermal Sensing显示文摘The combination of optical fiber with graphene has greatly expanded the application regimes of fiber optics,from dynamic optical control and ultrafast pulse generation to high precision sensing.However,limited by fabrication,previous graphene-fiber samples are typically limited in the micrometer to centimeter scale,which cannot take the inherent advantage of optical fibers—longdistance optical transmission.Here,we demonstrate kilometers long graphene-coated optical fiber(GCF)based on industrial graphene nanosheets and coating technique.The GCF shows unusually high thermal diffusivity of 24.99 mm^(2) s^(-1) in the axial direction,measured by a thermal imager directly.This enables rapid thermooptical response both in optical fiber Bragg grating sensors at one point(18-fold faster than conventional fiber)and in long-distance distributed fiber sensing systems based on backward Rayleigh scattering in optical fiber(15-fold faster than conventional fiber).This work realizes the industrial-level graphene-fiber production and provides a novel platform for two-dimensional material-based optical fiber sensing applications. | Yiyong Guo Bing Han Junting Du Shanshan Cao Hua Gao Ning An Yiwei Li Shujie An Zengling Ran Yue Lin Wencai Ren Yunjiang Rao Baicheng Yao | 2021 | Research2021，，1： | 2 |
| 10 | Fuel Characteristics of Biodiesel Produced from a High-Acid Oil from SoybeanSoapstock by Supercritical-Methanol Transesterification显示文摘 | LIN Cherngyuan LIN Yiwei | 2012 | Energies2012，5，： | 1 |
| 11 | Study the adsorption of phenol from aqueous solution on hydroxyapatite nanopowders 显示文摘 | LIN Kaili PAN Jiayong CHEN Yiwei | 2009 | Journal of Hazardous Materials2009，161，1： | 1 |
| 12 | Combine SVMs with various fea- ture selection strategies显示文摘 | CHEN Yiwei LIN C H | 2006 | Studies in fuzziness and soft computing2006，207，： | 1 |
| 13 | Association between apolipoprotein C3 Sst, T-455C, C-482T and C1100T polymorphisms and risk of coronary heart disease显示文摘 | Bin Lin Yiwei Huang Mingying Zhang | 2014 | BMJ Open2014，，4： | 1 |
| 14 | The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation显示文摘Acetaminophen(APAP)overdose is a major cause of liver injury.Neural precursor cell expressed developmentally downregulated 4—1(NEDD4-1)is an E3 ubiquitin ligase that has been implicated in the pathogenesis of numerous liver diseases;however,its role in APAP-induced liver injury(AILI)is unclear.Thus,this study aimed to investigate the role of NEDD4-1 in the pathogenesis of AILI.We found that NEDD4-1 was dramatically downregulated in response to APAP treatment in mouse livers and isolated mouse hepatocytes.Hepatocyte-specific NEDD4-1 knockout exacerbated APAP-induced mitochondrial damage and the resultant hepatocyte necrosis and liver injury,while hepatocyte-specific NEDD4-1 overexpression mitigated these pathological events both in vivo and in vitro.Additionally,hepatocyte NEDD4-1 deficiency led to marked accumulation of voltage-dependent anion channel 1(VDAC1)and increased VDAC1 oligomerization.Furthermore,VDAC1 knockdown alleviated AILI and weakened the exacerbation of AILI caused by hepatocyte NEDD4-1 deficiency.Mechanistically,NEDD4-1 was found to interact with the PPTY motif of VDAC1 through its WW domain and regulate K48-linked ubiquitination and degradation of VDAC1.Our present study indicates that NEDD4-1 is a suppressor of AILI and functions by regulating the degradation of VDAC1. | Yiwei Zhu Lin Lei Xinghui Wang Linfang Chen Wei Li Jinxia Li Chenchen Zhao Xiliang Du Yuxiang Song Wenwen Gao Guowen Liu Xinwei Li | 2023 | Acta Pharmaceutica Sinica B2023，13，4： | 1 |
| 15 | Ab initio electronic transport study of two-dimensional silicon carbide-based p–n junctions显示文摘Two-dimensional silicon carbide(2d-SiC) is a viable material for next generation electronics due to its moderate,direct bandgap with huge potential.In particular,its potential for p–n junctions is yet to be explored.In this paper,three types of 2d-SiC-based p–n junctions with different doping configuration are modeled.The doping configurations refer to partially replacing carbon with boron or nitrogen atoms along the zigzag or armchair direction,respectively.By employing density functional theory,we calculate the transport properties of the SiC based p–n junctions and obtain negative differential resistance and high rectification ratio.We also find that the junction along the zigzag direction with lower doping density exhibits optimized rectification performance.Our study suggests that 2d-SiC is a promising candidate as a material platform for future nano-devices. | Hanming Zhou Xiao Lin Hongwei Guo Shisheng Lin Yiwei Sun Yang Xu | 2017 | Journal of Semiconductors2017，38，3： | 1 |
| 16 | Polyhydroxyalkanoates of different structure synthesized by activated sludge with acetate and propionate as sole carbon source 显示文摘 | Lin Dongen Zhang Yiwei Sun Dongcheng | 2003 | Acta Scientiarum Naturalium Universitatis Stmyatseni2003，42，： | 1 |
| 17 | 显示文摘 | Lin Kaili Pan Jiayong Chen Yiwei | 2009 | Journal of Haz- ardous Materials2009，161，1： | 1 |
| 18 | Repression of interferon regulatory factor-4(IRF4)hyperactivation restricts murine lupus显示文摘Dear Editor,Hyperactivation of the type I interferon(IFN)signature has been observed in several systemic autoimmune conditions,and the type I IFN receptor antagonist Saphnelo(anifrolumab-fnia)has been approved in 2021 by the Food and Drug Administration(FDA)in the US.The launch of Saphnelo marked the only new treatment approved for systemic lupus erythematosus(SLE)in more than 10 years. | Shijun He Huihua Ding Li Chen Yiwei Shen Yuting Liu Fenghua Zhu Xiaoqian Yang Nan Shen Zemin Lin Jianping Zuo | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 1 |
| 19 | The gap-free genome of mulberry elucidates the architecture and evolution of polycentric chromosomes显示文摘Mulberry is a fundamental component of the global sericulture industry,and its positive impact on our health and the environment cannot be overstated.However,the mulberry reference genomes reported previously remained unassembled or unplaced sequences.Here,we report the assembly and analysis of the telomere-to-telomere gap-free reference genome of the mulberry species,Morus notabilis,which has emerged as an important reference in mulberry gene function research and genetic improvement.The mulberry gap-free reference genome produced here provides an unprecedented opportunity for us to study the structure and function of centromeres.Our results revealed that all mulberry centromeric regions share conserved centromeric satellite repeats with different copies.Strikingly,we found that M.notabilis is a species with polycentric chromosomes and the only reported polycentric chromosome species up to now.We propose a compelling model that explains the formation mechanism of new centromeres and addresses the unsolved scientific question of the chromosome fusion-fission cycle in mulberry species.Our study sheds light on the functional genomics,chromosome evolution,and genetic improvement of mulberry species. | Bi Ma Honghong Wang Jingchun Liu Lin Chen Xiaoyu Xia Wuqi Wei Zhen Yang Jianglian Yuan Yiwei Luo Ningjia He | 2023 | Horticulture Research2023，10，7： | 1 |
| 20 | Determination of pheny- lenediamine isomers in hair dyes by coal cinders micro - column extraction and MEKC 显示文摘 | WU YIWEI JIANG FENG CHEN LIN | 2011 | Anal Bionanal Chem2011，400，： | 1 |
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