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| 1 | Discovery of Late Cretaceous foraminifera in the Songliao Basin: Evidence from SK-1 and implications for identifying seawater incursions显示文摘The Songliao Basin is the largest oil-bearing basin in China.In the absence of sufficient evidence,the possibility of seawater incursion(s) into the Songliao Basin remains controversial.Recently,we discovered relatively abundant foraminifera fossils from units 1 and 2 of the Nenjiang Formation of borehole SK-1.Benthic foraminifera (Gavlinella sp.,Anomalinoides sp.,Pullenia sp.,Haplophragmoides sp.,Karrorulina hokkaidoana,Clavulinoides sp.),as well as planktonic foraminifera (Archaeoglobigerina blowi,Archaeoglobigerina cretacea and Hedbergella flandrini),were identified.These fossils were widely distributed in the marine Cretaceous.According to the global distribution of the above-mentioned planktonic foraminifera,the age of these fossil bearing strata appears to be Late Coniacian to Santonian.More importantly,these foraminifera provide direct evidence for marine water incursions into the Songliao Basin during deposition of the Lower Nenjiang Formation. | XI DangPeng WAN XiaoQiao FENG ZhiQiang LI Shun FENG ZiHui JIA JianZhong JING Xia SI WeiMin | 2011 | Chinese Science Bulletin2011，56，3： | 21 |
| 2 | The gas sensing properties of TiO_2 nanotubes synthesized by hydrothermal method显示文摘在这份报纸, TiO2 nanotubes 被热水的方法在 150 点用 10 mol/L NaOH | Yan Li Wang Shun Tan Jia Wang Zhi Jin Tan Qiu Xia Wu Zheng Jiao Ming Hong Wu | 2011 | Chinese Chemical Letters2011，22，5： | 7 |
| 3 | Interaction between the atmospheric boundary layer and a standalone wind turbine in Gansu—Part I: Field measurement显示文摘 | De Shun Li Tao Guo Yin Ran Li Jin Sen Hu Zhi Zheng Ye Li Yu Jia Di WenRui Hu RenNian Li | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，9： | 6 |
| 4 | Protection of gastric mucosa from ethanol induced injury by recombinant epidermal growth factor in rats显示文摘NTRODUCTIONEpidermalgrowthfactor(EGF)isasinglechainpolypeptidethatissecretedbysubmandibularandBrunner′sglandsandisapowerfulm... | XU Chun Di 1, GAN Ren Bao 2, CHEN Shun Nian 1, JIANG Shi Hu 1 and XU Jia Yu 1 | 1998 | World Journal of Gastroenterology1998，4，5： | 6 |
| 5 | Role of duck plague virus glycoprotein C in viral adsorption:Absence of specific interactions with cell surface heparan sulfate显示文摘Many mammalian herpes viruses utilize heparan sulfate(HS) moieties present on cell surface proteoglycans as receptors for cell entry, and this process also requires viral glycoprotein C(gC) homologues. However, our understanding of the role of gC in facilitating attachment of other alpha-herpes viruses such as the duck plague virus(DPV) remains preliminary. To study the role of gC during DPV infection, we used a gC-deleted mutant virus(DPV-ΔgC-EGFP). Examination of the viral copy number by real-time PCR, as well as time course studies of viral adsorption and proliferation revealed that gC was involved in the viral binding to the cell surface. The affinity of viral glycoproteins(g B-DPV, gC-DPV, and g E-DPV) to HS was assessed using a prokaryotic expression system and HiTrap^(TM) Heparin HP column chromatography. In addition, to confirm that gC played a role in the interaction between DPV and HS, viruses were treated with the HS analogue heparin and host cells were treated with its inhibitors heparinase prior to exposure to DPV-ΔgC-EGFP or wild-type strain Chinese virulent duck plague virus(DPV-CHv). The effects of heparin and heparinase on virus infectivity demonstrated that function of gC on viral adsorption is independent of interactions between gC and heparin sulfate on cell surface. All in all, this study demonstrated that the gC of DPV can mediate viral adsorption in an HS-independent manner, which distinguish it from the gC of some other alpha-herpes viruses. Future studies will be required to identify the receptors involved in gC protein binding to cells. This work provides us a foundation for further studies of examining the roles of gC in the adsorption during duck plague virus infection. | JING Yan-chun WU Ying SUN Kun-feng WANG Ming-shu CHENG An-chun CHEN Shun JIA Ren-yong ZHU De-kang LIU Ma-feng YANG Qiao JING Bo CHEN Xiao-yue | 2017 | Journal of Integrative Agriculture2017，16，5： | 5 |
| 6 | Peginterferon Alfa-2a Plus Ribavirin for the Treatment of Dual Chronic Infection With Hepatitis B and C Viruses显示文摘 | Chun–Jen Liu Wan–Long Chuang Chuan–Mo Lee Ming–Lung Yu Sheng–Nan Lu Shun–Sheng Wu Li–Ying Liao Chi–Ling Chen Hsing–Tao Kuo You–Chen Chao Shui–Yi Tung Sien–Sing Yang Jia–Horng Kao Chen–Hua Liu Wei–Wen Su Chih–Lin Lin Yung–Ming Jeng Pei–Jer Chen Ding–Shinn | 2009 | Gastroenterology2009，，2： | 3 |
| 7 | The establishment and evaluation of near infrared universal model to determinate the effective ingredient content in pesticide rapidly显示文摘一个近红外线的通用定量分析模型被建立到确定在杀虫剂 EC (hikernalisation ) 由的有效成分内容请(部分最少的广场) 算法,模型预兆的能力被外部检查方法评估。模型在从五个不同公司,和模型决心系数 R2 和 RMSECV (生气确认的根均方差)包含一样的活跃成分的样品之中被建立分别地,是 0.9997 和 0.0223 在预言的价值和严峻的集合样品的化学价值之间的相对错误在2.71%和3.36%之间,它显示方法到确定在由确定的通用模型的杀虫剂 EC 的有效成分内容能遇见 | Yan Mei Xiong Xiang Zhong Song Chang Zhou Chen Hong Ping Lin Guo Tang Yue Huang Jia Duan Shun Geng Min | 2012 | Chinese Chemical Letters2012，23，9： | 3 |
| 8 | The MING proposal at SHINE:megahertz cavity enhanced X‑ray generation显示文摘The cavity-based X-ray free-electron laser(XFEL)has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity,whereas the currently existing self-amplified spontaneous emission(SASE)XFEL is capable of generating ultra-short pulses with chaotic spectra.In general,a cavity-based XFEL can provide a spectral brightness three orders of magnitude higher than that of the SASE mode,thereby opening a new door for cutting-edge scientific research.With the development of superconducting MHz repetition-rate XFEL facilities such as FLASH,European-XFEL,LCLS-II,and SHINE,practical cavity-based XFEL operations are becoming increasingly achievable.In this study,megahertz cavity enhanced X-ray generation(MING)is proposed based on China’s first hard XFEL facility-SHINE,which we refer to as MING@SHINE. | Nan‑Shun Huang Zi‑Peng Liu Bang‑Jie Deng Zi‑Han Zhu Shao‑Hua Li Tao Liu Zheng Qi Jia‑Wei Yan Wei Zhang Sheng‑Wang Xiang Yang‑Yang Lei Ya Zhu Yong‑Zhou He Qi‑Bing Yuan Fei Gao Rong‑Bing Deng Sen Sun Zhi‑Di Lei Zhi‑Qiang Jiang Meng‑Qi Duan Yuan Zhuan Xue‑Fang Huang Peng‑Cheng Dong Zhong‑Liang Li Shang‑Yu Si Lian Xue Si Chen Yong‑Fang Liu Ya‑Jun Tong Hai‑Xiao Deng Zhen‑Tang Zhao | 2023 | Nuclear Science and Techniques2023，34，1： | 2 |
| 9 | Metabolite profiling of plasma and urine from rats with TNBS‐induced acute colitis using UPLC‐ESI‐QTOF‐MS‐based metabonomics – a pilot study显示文摘 | Xiaojun Zhang Franky F. K. Choi Yan Zhou Feung P. Leung Shun Tan Shuhai Lin Hongxi Xu Wei Jia Joseph J. Y. Sung Zongwei Cai Zhaoxiang Bian | 2012 | FEBS Journal2012，，： | 2 |
| 10 | Immunogenicity and protective efficacy of DHBV DNA vaccines expressing envelope and capsid fusion proteins in ducks delivered by attenuated Salmonella typhimurium显示文摘Duck hepatitis B virus(DHBV) shares many basic characteristics with hepatitis B virus(HBV) and is an attractive model for vaccine development. In this study, DHBV DNA vaccines were designed to express envelope and capsid fusion proteins to enhance the breadth of immune response in ducks. Attenuated Salmonella typhimurium(SL7207) was used as a carrier and adjuvant to boost the magnitude of immune response. Based on this strategy, novel DNA vaccines(SL7207-p VAX1-LC and SL7207-p VAX1-SC) were generated. Growth kinetics, genetic stabilities and relative transcription levels of the L, S and C genes introduced by these vaccine strains were measured before inoculation to guarantee safety and efficacy. The relative transcript levels of the CD4 and CD8 T genes and the antibody levels(Ig Y) in ducks receiving the vaccines were higher than those in single gene delivered groups. Additionally, the copy number of covalently closed circular DNA in hepatocytes after DHBV challenge also provided evidence that our fusion vaccines could enhance the protective efficiency against DHBV infection in ducks. | LIU Si-yang JIA Ren-yong LI Qing-qing FENG Dai-shen SHEN Hao-yue YANG Cui WANG Ming-shu ZHU De-kang CHEN Shun LIU Ma-feng ZHAO Xin-xin YIN Zhong-qiong JING Bo CHENG An-chun | 2018 | Journal of Integrative Agriculture2018，17，4： | 2 |
| 11 | Therblig-based energy supply modeling of computer numerical control machine tools显示文摘 | YU Jingxiang TANG Renzheng JIA Shun | 2014 | Journal of Cleaner Production2014，65，1： | 1 |
| 12 | A Study in the adsorption behaviors of Cr (Ⅱ) on crosslinked cationic starches显示文摘 | Wei Jia Shun Feng | 2004 | Journal of Polymer Research2004，11，3： | 1 |
| 13 | Dynamic self-assembly synthesis and controlled release as drug vehicles of porous hollow silica nanoparticles显示文摘 | Shun Tan Qiuxia Wu Jia Wang Yanli Wang Xiaolei Liu Keke Sui Xiaoyong Deng Haifang Wang Minghong Wu | 2011 | Microporous and Mesoporous Materials2011，，2： | 1 |
| 14 | Therblig- based Energy Demand Modeling Methodology of Machining Process to Support Intelligent Manufac- turing显示文摘 | Jia Shun Tang Renzhong Lia Jingxiang | 2014 | Journal of Intelligent Manufacturing2014，25，5： | 1 |
| 15 | Therblig- based Energy Supply Modeling of Computer Nu- merical Control Machine Tools显示文摘 | Jia Shun Tang Renzhong Lia Jingxiang | 2014 | Journal of Clean- er Production2014，65，2： | 1 |
| 16 | The codon-optimized capsid gene of duck circovirus can be highly expressed in yeast and self-assemble into virus-like particles显示文摘The capsid(Cap) protein, which is the only structural protein of duck circovirus(DuCV), is the most important antigen for the development of vaccines against DuCV and the virus' s serological diagnostic methods. In order to use yeast expression system to produce a large quantities of DuCV Cap protein which is close to its natural form to display the antigen peptides perfectly, the Cap gene was optimized into the codon-optimized capsid(Opt-Cap) gene towards the preference of yeast firstly. Then, the genes of Cap and Opt-Cap were separately cloned into pPIC9K plasmid and transformed into Picha pastoris GS115. The strains that displayed the phenotype of Mut^+ and contained multiple inserts of expression cassette were selected from those colonies. After the induction expression, the secretory type of Cap protein, which was about 43 kDa, was best expressed under 0.5%(v/v) methanol and sorbitol induction. Compared with the Cap gene, the expression level of Opt-Cap gene was much higher. What's more, the purified Cap protein had a good reactivity to its specific polyclone antibody and DuCV-positive serum, and it was able to self-assemble into virus-like particles(VLPs). These VLPs, with a diameter of 15–20 nm and without a nucleic acid structure, showed a high level of similarity to DuCV particles in size and shape. All of the results demonstrated that, based on the codon-optimization, it is suitable to use the P. pastoris expression system to produce DuCV VLPs on a large scale. It is the first time that a large amounts of DuCV VLPs were produced successfully in P. pastoris, which might be particularly useful for the further studies of serological diagnosis and vaccines of DuCV. | YANG Cui XU Yu JIA Ren-yong LIU Si-yang WANG Ming-shu ZHU De-kang CHEN Shun LIU Ma-feng ZHAO Xin-xin SUN Kun-feng JING Bo YIN Zhong-qiong CHENG An-chun | 2017 | Journal of Integrative Agriculture2017，16，7： | 1 |
| 17 | Deformation and Stability Study of PBA Extension Method Based on Air Defense Tunnel显示文摘 | Jia Jian Zhou Shun Hua Yao Xi Ping Shen Chen | 2012 | 2012 (204)2012，，204： | 1 |
| 18 | Study of pullout strength of the Lower Cervical Posterior Route Screw Techniques显示文摘 | XIE Ning LI jia shun JIA Lian Shun | 2001 | Orthop J Chin2001，8，： | 1 |
| 19 | Hydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats显示文摘 | Yun Chang Tan Feng Xie Hui Lu Zhang Yu Li Zhu Ke Chen Hua Min Tan Ben Shun Hu Jia Mei Yang Jing Wang Tan | 2013 | Clinics and Research in Hepatology and Gastroenterology2013，，： | 1 |
| 20 | Construction of an Infectious Clone for Mosquito-Derived Tembusu Virus Prototypical Strain显示文摘Dear Editor,Duck Tembusu virus(DTMUV),a member of the Flavivirus genus within the Flaviviridae family,has caused huge economic losses to the poultry industry in China and even in Asia since 2010(Zhang et al.2017).The first strain of Tembusu virus(TMUV)MM_1775 was isolated from mosquitoes in 1955 in Malaysia(Platt et al.1975).DTMUV CQW1 strain(GenBank:KM233707.1)was isolated from the liver tissue of Cherry Valley ducks in southwest China in 2015(Zhu et al.2015).The positive control rCQW1 was rescued from an infectious clone that contained the full-length cDNA of CQW1.And the complete cDNA was positioned under the control of the T7 promoter elements for in vitro transcription(Chen et al.2018).The relationship between TMUV evolution and pathogenic variants has not been revealed.The fundamental reason is the lack of the in vitro operation platform for the prototypical strain genome. | Xiaoli Wang Yu He Jiaqi Guo Bowen Jiang Mingshu Wang Renyong Jia Dekang Zhu Mafeng Liu Xinxin Zhao Qiao Yang Ying Wu Shaqiu Zhang Yunya Liu Ling Zhang Yanling Yu Anchun Cheng Shun Chen | 2021 | Virologica Sinica2021，36，6： | 1 |
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