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| 1 | Neural Tract Degeneration Correlates with Functional Impairment in Patients with Anoxic Brain Injury:A Tract-based Spatial Statistics Study显示文摘Dear Editor,Anoxic brain injury(ABI)is a devastating event caused by cardiac arrest,chemical exposure,or trauma.Despite recent advances in medical diagnostic techniques and treatments,the survival rate after ABI is still very low.Previous studies have reported that 52.6%-64.0%of people who received cardiopulmonary resuscitation after nontraumatic cardiac arrest die,and 9.0%-18.6%remain in a permanent vegetative state within 28 days of treatment[1,2]. | Ji-Yun Park Sung Ho Park Jeong-Hee Yang Han Do Lee Jiho Lee Ki-Hyun Byeon Seo Young Park Dongseok Yang | 2020 | Neuroscience Bulletin2020，36，8： | 1 |
| 2 | Immobilization of the cross-linked para -nitrobenzyl esterase of Bacillus subtilis aggregates onto magnetic beads显示文摘 | Jae-Min Park Mina Kim Ju-Yong Park Dong-Hun Lee Kyu-Ho Lee Jiho Min Yang-Hoon Kim | 2009 | Process Biochemistry2009，，2： | 1 |
| 3 | Investigation of the annealing effects on the structural and optical properties of sputtered ZnO thin films显示文摘 | Mina Jung Juyoung Lee Seungwhan Park Hongseung Kim Jiho Chang | 2005 | Journal of Crystal Growth2005，，3： | 1 |
| 4 | Immobilization of lysozyme-CLEA onto electrospun chitosan nanofiber for effective antibacterial applications显示文摘 | Jae-Min Park Mina Kim Hyun-Sung Park Am Jang Jiho Min Yang-Hoon Kim | 2013 | International Journal of Biological Macromolecules2013，，： | 1 |
| 5 | Two-photon interference between continuous-wave coherent photons temporally separated by a day显示文摘An understanding of the phenomenon of light interference forms the kernel underlying the discovery of the nature of light from the viewpoints of both classical physics and quantum physics.Here we report on two-photon interference with temporally separated continuous-wave coherent photons by using a temporal post-selection method with an arbitrary time delay.Although the temporal separation of a day between the photons is considerably longer than the coherence time of the light source,we observe the Hong–Ou–Mandel(HOM)interference of the pairwise two-photon state.Furthermore,we experimentally demonstrate the HOM interference observed in one of the interferometer-output modes by using only one single-photon detector for a large temporal separation. | DANBI KIM JIHO PARK TAEK JEONG HEONOH KIM HAN SEB MOON | 2020 | Photonics Research2020，8，3： | 0 |
| 6 | U-IMPACT:a universal 3D microfluidic cell culture platform显示文摘The development of organs-on-a-chip has resulted in advances in the reconstruction of 3D cellular microenvironments.However,there remain limitations regarding applicability and manufacturability.Here,we present an injection-molded plastic array 3D universal culture platform(U-IMPACT)for various biological applications in a single platform,such as cocultures of various cell types,and spheroids(e.g.,tumor spheroids,neurospheres)and tissues(e.g.,microvessels).The U-IMPACT consists of three channels and a spheroid zone with a 96-well plate form factor.Specifically,organoids or spheroids(~500μm)can be located in designated areas,while cell suspensions or cellladen hydrogels can be selectively placed in three channels.For stable multichannel patterning,we developed a new patterning method based on capillary action,utilizing capillary channels and the native contact angle of the materials without any modification.We derived the optimal material hydrophilicity(contact angle of the body,45–90°;substrate,<30°)for robust patterning through experiments and theoretical calculations.We demonstrated that the U-IMPACT can implement 3D tumor microenvironments for angiogenesis,vascularization,and tumor cell migration.Furthermore,we cultured neurospheres from induced neural stem cells.The U-IMPACT can serve as a multifunctional organ-on-achip platform for high-content and high-throughput screening. | Seung-Ryeol Lee Youngtaek Kim Suryong Kim Jiho Kim Seonghyuk Park Stephen Rhee Dohyun Park Byungjun Lee Kyusuk Baek Ho-Young Kim Noo Li Jeon | 2022 | Microsystems & Nanoengineering2022，8，6： | 0 |
| 7 | Hong–Ou–Mandel interference of two independent continuous-wave coherent photons显示文摘Interference between two completely independent photons lies at the heart of many photonic quantum information applications such as quantum repeaters,teleportation,and quantum key distribution.Here,we report the observation of Hong–Ou–Mandel(HOM)interference with two independent continuous-wave coherent light sources that are neither synchronized nor share any common reference.To prepare indistinguishable photons from two independent laser sources,we employ high-precision frequency-stabilization techniques using the 5 S1∕2(F=3)-5P1∕2(F'=3)transition line of 85 Rb atoms.We successfully observe an HOM interference fringe with two independent continuous-wave coherent photons originating from either the frequency-locked or the frequency-modulated lasers.An interference fringe involving two-photon beating is also observed when the frequency difference between the two interfering photons is beyond the spectral bandwidth of the individual coherent photons.We carry out further experiments to verify the robustness of the source preparation regardless of the separation distance between the two independent photon sources. | HEONOH KIM DANBI KIM JIHO PARK AND HAN SEB MOON | 2020 | Photonics Research2020，8，9： | 0 |
| 8 | Plant-based,adjuvant-free,potent multivalent vaccines for avian influenza virus via Lactococcus surface display显示文摘Influenza epidemics frequently and unpredictably break out all over the world,and seriously affect the breeding industry and human activity.Inactivated and live attenuated viruses have been used as protective vaccines but exhibit high risks for biosafety.Subunit vaccines enjoy high biosafety and specificity but have a few weak points compared to inactivated virus or live attenuated virus vaccines,especially in low immunogenicity.In this study,we developed a new subunit vaccine platform for a potent,adjuvant-free,and multivalent vaccination.The ectodomains of hemagglutinins(HAs)of influenza viruses were expressed in plants as trimers(tHAs)to mimic their native forms.tHAs in plant extracts were directly used without purification for binding to inactivated Lactococcus(iLact)to produce iLact-tHAs,an antigen-carrying bacteria-like particle(BLP).tHAs BLP showed strong immune responses in mice and chickens without adjuvants.Moreover,simultaneous injection of two different antigens by two different formulas,t^(HAH5N6+H9N2) BLP or a combination of t^(HAH5N6) BLP and t^(HAH9N2) BLP,led to strong immune responses to both antigens.Based on these results,we propose combinations of plant-based antigen production and BLP-based delivery as a highly potent and cost-effective platform for multivalent vaccination for subunit vaccines. | Shi-Jian Song Gyeong-Im Shin Jinyong Noh Jiho Lee Deok-Hwan Kim Gyeongryul Ryu Gyeongik Ahn Hyungmin Jeon Hai-Ping Diao Youngmin Park Min Gab Kim Woe-Yeon Kim Young-Jin Kim Eun-Ju Sohn Chang Seon Song Inhwan Hwang | 2021 | Journal of Integrative Plant Biology2021，63，8： | 0 |
| 9 | Improving Method of Anomaly Detection Performance for Industrial IoT Environment显示文摘Industrial Control System(ICS),which is based on Industrial IoT(IIoT),has an intelligent mobile environment that supports various mobility,but there is a limit to relying only on the physical security of the ICS environment.Due to various threat factors that can disrupt the workflow of the IIoT,machine learning-based anomaly detection technologies are being presented;it is also essential to study for increasing detection performance to minimize model errors for promoting stable ICS operation.In this paper,we established the requirements for improving the anomaly detection performance in the IIoT-based ICS environment by analyzing the related cases.After that,we presented an improving method of the performance of a machine learning model specialized for IIoT-based ICS,which increases the detection rate by applying correlation coefficients and clustering;it provides a mechanism to predict thresholds on a per-sequence.Likewise,we adopted the HAI dataset environment that actively reflected the characteristics of IIoT-based ICS and demonstrated that performance could be improved through comparative experiments with the traditional method and our proposed method.The presented method can further improve the performance of commonly applied error-based detection techniques and includes a primary method that can be enhanced over existing detection techniques by analyzing correlation coefficients between features to consider feedback between ICS components.Those can contribute to improving the performance of several detection models applied in ICS and other areas. | Junwon Kim Jiho Shin Ki-Woong Park Jung Taek Seo | 2022 | Computers, Materials & Continua2022，，9： | 0 |
| 10 | Second-order interference of true thermal light from a warm atomic ensemble in two independent unbalanced interferometers显示文摘We report the demonstration of a second-order interference experiment by use of thermal light emitted from a warm atomic ensemble in two spatially separated unbalanced Michelson interferometers(UMIs).This novel multipath correlation interference with thermal light has been theoretically proposed by Tamma[New J.Phys.18,032002(2016)].In our experiment,the bright thermal light used for second-order interference is superradiantly emitted via collective two-photon coherence in Doppler-broadened cascade-type 87 Rb atoms.Owing to the long coherence time of the thermal light from the atomic ensemble,we observe its second-order interference in the two independent UMIs by means of time-resolved coincidence detection.The temporal waveforms of the interfering thermal light in the two spatially separated UMIs exhibit similarities with the temporal two-photon waveform of time–energy entangled photon pairs in Franson interferometry.Our results can contribute toward a better understanding of the relation between first-and second-order interferences that are at the heart of photonics-based quantum information science. | JIHO PARK HEONOH KIM HAN SEB MOON | 2021 | Photonics Research2021，9，1： | 0 |
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