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| 1 | Effects of land use change and water reuse options on urban water cycle显示文摘The aim of this article was to study the effects of land use change and water reuse options on an urban water cycle.A water cycle analysis was performed on the Goonja drainage basin,located in metropolitan Seoul,using the Aquacycle model.The chronological effects of urbanization were first assessed for the land uses of the Goonja drainage basin from 1975 to 2005,where the ratio of impervious areas ranged from 43% to 84%.Progressive urbanization was identified as leading to a decrease in evapotranspiration (29%),an increase in surface runoff (41%) and a decrease in groundwater recharge (74%),indicating a serious distortion of the water cycle.From a subsequent analysis of the water reuse options,such as rainwater use and wastewater reuse,it is concluded that wastewater reuse seemed to have an advantage over rainwater use for providing a consistent water supply throughout the year for a country like Korea,where the rainy season is concentrated during the summer monsoon. | Jiho Lee Gijung Pak Chulsang Yoo Sangdan Kim Jaeyoung Yoon | 2010 | Journal of Environmental Sciences2010，22，6： | 6 |
| 2 | Deep-learning-based inverse design model for intelligent discovery of organic molecules显示文摘The discovery of high-performance functional materials is crucial for overcoming technical issues in modern industries.Extensive efforts have been devoted toward accelerating and facilitating this process,not only experimentally but also from the viewpoint of materials design.Recently,machine learning has attracted considerable attention,as it can provide rational guidelines for efficient material exploration without time-consuming iterations or prior human knowledge.In this regard,here we develop an inverse design model based on a deep encoder-decoder architecture for targeted molecular design.Inspired by neural machine language translation,the deep neural network encoder extracts hidden features between molecular structures and their material properties,while the recurrent neural network decoder reconstructs the extracted features into new molecular structures having the target properties.In material design tasks,the proposed fully data-driven methodology successfully learned design rules from the given databases and generated promising light-absorbing molecules and host materials for a phosphorescent organic light-emitting diode by creating new ligands and combinatorial rules. | Kyungdoc Kim Seokho Kang Jiho Yoo Youngchun Kwon Youngmin Nam Dongseon Lee Inkoo Kim Youn-Suk Choi Yongsik Jung Sangmo Kim Won-Joon Son Jhunmo Son Hyo Sug Lee Sunghan Kim Jaikwang Shin Sungwoo Hwang | 2018 | npj Computational Materials2018，，1： | 4 |
| 3 | Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7显示文摘The voltage-gated Na^+ channel subtype Nav1.7 is important for pain and itch in rodents and humans. We previously showed that a Nav1.7-targeting monoclonal antibody(SVmab) reduces Na+ currents and pain and itch responses in mice. Here, we investigated whether recombinant SVmab(rSVmab) binds to and blocks Nav1.7 similar to SVmab. ELISA tests revealed that SVmab was capable of binding to Nav1.7-expressing HEK293 cells,mouse DRG neurons, human nerve tissue, and the voltagesensor domain Ⅱ of Nav1.7. In contrast, rSVmab showed no or weak binding to Nav1.7 in these tests. Patch-clamp recordings showed that SVmab, but not rSVmab, markedly inhibited Na+ currents in Nav1.7-expressing HEK293 cells. Notably, electrical field stimulation increased the blocking activity of SVmab and rSVmab in Nav1.7-expressing HEK293 cells. SVmab was more effective than rSVmab in inhibiting paclitaxel-induced mechanical allodynia. SVmab also bound to human DRG neurons and inhibited their Na^+ currents. Finally, potential reasons for the differential efficacy of SVmab and rSVmab and future directions are discussed. | Sangsu Bang Jiho Yoo Xingrui Gong Di Liu Qingjian Han Xin Luo Wonseok Chang Gang Chen Sang-Taek Im Yong Ho Kim Judith A.Strong Ma-Zhong Zhang Jun-Ming Zhang Seok-Yong Lee Ru-Rong Ji | 2018 | Neuroscience Bulletin2018，34，1： | 2 |
| 4 | Laser engraving of micro-patterns on roll surfaces显示文摘 | Jiho Uh Jin Lee Yoon H Kim | 2002 | ISIJ International2002，42，11： | 1 |
| 5 | Design a Switch Wrapper for SNA On-Chip-Network 显示文摘 | Jiho Chang Jongsu Yi Jun Seong Kim et aI | 2006 | IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences2006，89，6： | 1 |
| 6 | Fractionated wide-field radiation therapy followed by fractionated local-field Irradiation for treating widespread painful bone metastasis显示文摘 | Yongkan Ki Wontaek Kim Jiho Nam | 2011 | International Jour- nal of Radiation Oncology2011，79，1： | 1 |
| 7 | Accelerated Degradation of Dipentyl Phthalate by Fusarium oxysporum f. sp. pisi Cutinase and Toxicity Evaluation of Its Degradation Products Using Bioluminescent Bacteria显示文摘 | Ji-Young Ahn Yang-Hoon Kim Jiho Min Jeewon Lee | 2006 | Current Microbiology2006，，5： | 1 |
| 8 | Biodegradation of dipropyl phthalate and toxicity of its degradation products: a comparison of Fusarium oxysporum f. sp. pisi cutinase and Candida cylindracea esterase显示文摘 | Yang-Hoon Kim Jiho Min Kyung-Dong Bae Man Bock Gu Jeewon Lee | 2005 | Archives of Microbiology2005，，1： | 1 |
| 9 | Fractionated wide-field radiation therapy followed by fractionated local-field Irradiation for treating widespread painful bone metastasis 显示文摘 | Yongkan Ki Wontaek Kim Jiho Nam | 2011 | International Journal of Radiation Oncology2011，79，1： | 1 |
| 10 | Simple method of measuring ocular rotation in supine position during small incision lenticule extraction显示文摘AIM:To introduce a novel measurement method of static cyclotorsion in small incision lenticule extraction(SMILE)and to investigate the effect of preoperative parameters on cyclotorsion and the effect of cyclotorsion on postoperative outcomes.METHODS:The medical records of 242 patients and 484 eyes who under went SMILE surger y were retrospectively reviewed.Preoperative intraocular pressure,refractive error,and corneal thickness were investigated.Refractive values and visual acuity were measured at 1d,1,3,and 6mo.Ocular cyclotorsion in the supine position was measured by calculating the location and angle of the incision site of the cornea in the anterior slit photograph taken after surgery.RESULTS:Of the total 484 eyes in 242 patients,preopera tive means phericale quivalent(SE)was-4.10±1.64 D,and the mean astigmatism was-0.82±0.74 D.Uncorrected distance visual acuity(UCVA)and SE improved significantly after the surgery.Moreover,219(45.2%)eyes had excyclotorsion,235(48.6%)eyes had incyclotorsion,and 30(6.2%)eyes had no torsion.The right eyes tended to be excyclotorted,and the left eyes tended to be incyclotorted(P<0.01).The mean cyclotorsion was 1.18°±3.69°,and the mean absolute value of cyclotorsion was 3.14°±2.26°.The range of cyclotorsion was 0.5°–11.4°.It was found that the smaller the preoperative sphere,the higher the amount of cyclotorsion(r=0.11,P=0.016).There was no significant association between the amount of cyclotorsion and preoperative astigmatism.There was no correlation between sex,preoperative corneal thickness,preoperative intraocular pressure,amount of cyclotorsion,and direction of cyclotorsion.The ratio of right eye excyclotorsion and left eye incyclotorsion on 1d was higher than that at 1,3,and 6mo(all P<0.01).There was no difference between the 1,3,and 6mo results in the right and left eyes(P=0.15,P=0.16,respectively).CONCLUSION:The newly devised ocular cyclotorsion measurement method can be used to evaluate ocular cyclotorsion after SMILE.Preoperative SE is associated with the amount of cyclotorsion,however,cyclotorsion doesn't have a significant effect on the results of SMILE surgery. | Jiho Song Hwanho Lee Moon Sun Jung Jae-hyung Kim | 2022 | International Journal of Ophthalmology(English edition)2022，15，8： | 1 |
| 11 | Immobilization of the cross-linked para -nitrobenzyl esterase of Bacillus subtilis aggregates onto magnetic beads显示文摘 | Jae-Min Park Mina Kim Ju-Yong Park Dong-Hun Lee Kyu-Ho Lee Jiho Min Yang-Hoon Kim | 2009 | Process Biochemistry2009，，2： | 1 |
| 12 | Investigation of the annealing effects on the structural and optical properties of sputtered ZnO thin films显示文摘 | Mina Jung Juyoung Lee Seungwhan Park Hongseung Kim Jiho Chang | 2005 | Journal of Crystal Growth2005，，3： | 1 |
| 13 | Immobilization of lysozyme-CLEA onto electrospun chitosan nanofiber for effective antibacterial applications显示文摘 | Jae-Min Park Mina Kim Hyun-Sung Park Am Jang Jiho Min Yang-Hoon Kim | 2013 | International Journal of Biological Macromolecules2013，，： | 1 |
| 14 | Fractionated wide - field radiation therapy followed by fractionated local - rield irradiation for treating widespread painful bone metastasis 显示文摘 | Yongkan Ki Wontaek Kim Jiho Nam | 2011 | Int J Radiat Oncol2011，79，1： | 1 |
| 15 | Two-photon interference between continuous-wave coherent photons temporally separated by a day显示文摘An understanding of the phenomenon of light interference forms the kernel underlying the discovery of the nature of light from the viewpoints of both classical physics and quantum physics.Here we report on two-photon interference with temporally separated continuous-wave coherent photons by using a temporal post-selection method with an arbitrary time delay.Although the temporal separation of a day between the photons is considerably longer than the coherence time of the light source,we observe the Hong–Ou–Mandel(HOM)interference of the pairwise two-photon state.Furthermore,we experimentally demonstrate the HOM interference observed in one of the interferometer-output modes by using only one single-photon detector for a large temporal separation. | DANBI KIM JIHO PARK TAEK JEONG HEONOH KIM HAN SEB MOON | 2020 | Photonics Research2020，8，3： | 0 |
| 16 | U-IMPACT:a universal 3D microfluidic cell culture platform显示文摘The development of organs-on-a-chip has resulted in advances in the reconstruction of 3D cellular microenvironments.However,there remain limitations regarding applicability and manufacturability.Here,we present an injection-molded plastic array 3D universal culture platform(U-IMPACT)for various biological applications in a single platform,such as cocultures of various cell types,and spheroids(e.g.,tumor spheroids,neurospheres)and tissues(e.g.,microvessels).The U-IMPACT consists of three channels and a spheroid zone with a 96-well plate form factor.Specifically,organoids or spheroids(~500μm)can be located in designated areas,while cell suspensions or cellladen hydrogels can be selectively placed in three channels.For stable multichannel patterning,we developed a new patterning method based on capillary action,utilizing capillary channels and the native contact angle of the materials without any modification.We derived the optimal material hydrophilicity(contact angle of the body,45–90°;substrate,<30°)for robust patterning through experiments and theoretical calculations.We demonstrated that the U-IMPACT can implement 3D tumor microenvironments for angiogenesis,vascularization,and tumor cell migration.Furthermore,we cultured neurospheres from induced neural stem cells.The U-IMPACT can serve as a multifunctional organ-on-achip platform for high-content and high-throughput screening. | Seung-Ryeol Lee Youngtaek Kim Suryong Kim Jiho Kim Seonghyuk Park Stephen Rhee Dohyun Park Byungjun Lee Kyusuk Baek Ho-Young Kim Noo Li Jeon | 2022 | Microsystems & Nanoengineering2022，8，6： | 0 |
| 17 | Hong–Ou–Mandel interference of two independent continuous-wave coherent photons显示文摘Interference between two completely independent photons lies at the heart of many photonic quantum information applications such as quantum repeaters,teleportation,and quantum key distribution.Here,we report the observation of Hong–Ou–Mandel(HOM)interference with two independent continuous-wave coherent light sources that are neither synchronized nor share any common reference.To prepare indistinguishable photons from two independent laser sources,we employ high-precision frequency-stabilization techniques using the 5 S1∕2(F=3)-5P1∕2(F'=3)transition line of 85 Rb atoms.We successfully observe an HOM interference fringe with two independent continuous-wave coherent photons originating from either the frequency-locked or the frequency-modulated lasers.An interference fringe involving two-photon beating is also observed when the frequency difference between the two interfering photons is beyond the spectral bandwidth of the individual coherent photons.We carry out further experiments to verify the robustness of the source preparation regardless of the separation distance between the two independent photon sources. | HEONOH KIM DANBI KIM JIHO PARK AND HAN SEB MOON | 2020 | Photonics Research2020，8，9： | 0 |
| 18 | 鄂尔多斯博物馆显示文摘MAD设计的鄂尔多斯博物馆近日落成,它好像是空降在沙丘上的巨大时光洞窟,其内部充满自然的光线,正将城市废墟转化为充满诗意的公共文化空间。六年前还是一片戈壁荒野的内蒙古鄂尔多斯新城今天充满争议,而争议本身已经将其置于更广泛的中国当代城市文化反思的焦点,它让公众重新理解地方传统和城市梦想的关联和矛盾,同时, | 尚荔 Andrew C.Bryant Howard Jiho Kim 向玲 Linda Stannieder Matthias Helmreich 郑涛 覃立超 杨霖 孙杰明 银钊 杜志坚 袁中伟 袁涛 谢新宇 刘维炜 Felipe Escudero Sophia Tang Diego Perez Art terry Jtravis B Russett Dustin Harris Iwan Baan | 2012 | 建筑创作2012，，6： | 0 |
| 19 | Prediction of Cold and Heat Patterns Using Anthropometric Measures Based on Machine Learning显示文摘Objective: To examine the association of body shape with cold and heat patterns, to determine which anthropometric measure is the best indicator for discriminating between the two patterns, and to investigate whether using a combination of measures can improve the predictive power to diagnose these patterns. Methods: Based on a total of 4,859 subjects(3,000 women and 1,859 men), statistical analyses using binary logistic regression were performed to assess the significance of the difference and the predictive power of each anthropometric measure, and binary logistic regression and Naive Bayes with the variable selection technique were used to assess the improvement in the predictive power of the patterns using the combined measures. Results: In women, the strongest indicators for determining the cold and heat patterns among anthropometric measures were body mass index(BMI) and rib circumference; in men, the best indicator was BMI. In experiments using a combination of measures, the values of the area under the receiver operating characteristic curve in women were 0.776 by Naive Bayes and 0.772 by logistic regression, and the values in men were 0.788 by Naive Bayes and 0.779 by logistic regression. Conclusions: Individuals with a higher BMI have a tendency toward a heat pattern in both women and men. The use of a combination of anthropometric measures can slightly improve the diagnostic accuracy. Our findings can provide fundamental information for the diagnosis of cold and heat patterns based on body shape for personalized medicine. | Bum Ju Lee Jae Chul Lee Jiho Nam Jong Yeol Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，1： | 0 |
| 20 | Plant-based,adjuvant-free,potent multivalent vaccines for avian influenza virus via Lactococcus surface display显示文摘Influenza epidemics frequently and unpredictably break out all over the world,and seriously affect the breeding industry and human activity.Inactivated and live attenuated viruses have been used as protective vaccines but exhibit high risks for biosafety.Subunit vaccines enjoy high biosafety and specificity but have a few weak points compared to inactivated virus or live attenuated virus vaccines,especially in low immunogenicity.In this study,we developed a new subunit vaccine platform for a potent,adjuvant-free,and multivalent vaccination.The ectodomains of hemagglutinins(HAs)of influenza viruses were expressed in plants as trimers(tHAs)to mimic their native forms.tHAs in plant extracts were directly used without purification for binding to inactivated Lactococcus(iLact)to produce iLact-tHAs,an antigen-carrying bacteria-like particle(BLP).tHAs BLP showed strong immune responses in mice and chickens without adjuvants.Moreover,simultaneous injection of two different antigens by two different formulas,t^(HAH5N6+H9N2) BLP or a combination of t^(HAH5N6) BLP and t^(HAH9N2) BLP,led to strong immune responses to both antigens.Based on these results,we propose combinations of plant-based antigen production and BLP-based delivery as a highly potent and cost-effective platform for multivalent vaccination for subunit vaccines. | Shi-Jian Song Gyeong-Im Shin Jinyong Noh Jiho Lee Deok-Hwan Kim Gyeongryul Ryu Gyeongik Ahn Hyungmin Jeon Hai-Ping Diao Youngmin Park Min Gab Kim Woe-Yeon Kim Young-Jin Kim Eun-Ju Sohn Chang Seon Song Inhwan Hwang | 2021 | Journal of Integrative Plant Biology2021，63，8： | 0 |
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