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28篇 您的检索式:作者名="JING Haoran"
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1Single and competitive adsorption affinity of heavy metals toward peanut shell-derived biochar and its mechanisms in aqueous systems显示文摘Converting peanut shells into biochar by pyrolysis was considered an environmentally friendly and efficient method for agricultural solid waste disposal.The properties of peanut shell-derived biochar(PBC)under different temperature and its adsorption capacity of heavy metals were investigated.It was found that PBC400 exhibited the highest cumulative capability for heavy metals elimination in single solute because of its high specific surface area and rich functional groups.Furthermore,the competitive adsorption revealed that PBC had a substantial difference in adsorption affinity from diverse heavy metal ions,sorption capacity decreased as Pb2+>Cu2+>Cd2+>Ni2+>Zn2+,which was lower than in a single solute.The adsorption process using selected biochar was optimized with respect to p H,reaction time,adsorbent dose,and initial concentration of heavy metals.The kinetic data was well fitted with PSO model,and the Langmuir model was adopted for adsorption equilibrium data in both cases of single solutes and mixed solutes for all heavy metals,which indicated that the removal course was primarily explained by monolayer adsorption,and chemical adsorption occupied an important role.Therefore,peanut shells derived biochar could be a potential and green adsorbent for wastewater treatment.Rui Shan Yueyue Shi Jing Gu YazhuoWang Haoran Yuan 2020Chinese Journal of Chemical Engineering2020,28,5:14
2SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation显示文摘Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is the ongoing global pandemic that poses substantial challenges to public health worldwide.A subset of COVID-19 patients experience systemic inflammatory response,known as cytokine storm,which may lead to death.Receptor-interacting serine/threonine-protein kinase 1(RIPK1)is an important mediator of inflammation and cell death.Here,we examined the interaction of RIPK1-mediated innate immunity with SARS-CoV-2 infection.We found evidence of RIPK1 activation in human COVID-19 lung pathological samples,and cultured human lung organoids and ACE2 transgenic mice infected by SARS-CoV-2.Inhibition of RIPK1 using multiple smallmolecule inhibitors reduced the viral load of SARS-CoV-2 in human lung organoids.Furthermore,therapeutic dosing of the RIPK1 inhibitor Nec-1s reduced mortality and lung viral load,and blocked the CNS manifestation of SARS-CoV-2 in ACE2 transgenic mice.Mechanistically,we found that the RNA-dependent RNA polymerase of SARS-CoV-2,NSP12,a highly conserved central component of coronaviral replication and transcription machinery,promoted the activation of RIPK1.Furthermore,NSP12323L variant,encoded by the SARS-CoV-2 C14408T variant first detected in Lombardy,Italy,that carries a Pro323Leu amino acid substitution in NSP12,showed increased ability to activate RIPK1.Inhibition of RIPK1 downregulated the transcriptional induction of proinflammatory cytokines and host factors including ACE2 and EGFR that promote viral entry into cells.Our results suggest that SARS-CoV-2 may have an unexpected and unusual ability to hijack the RIPK1-mediated host defense response to promote its own propagation and that inhibition of RIPK1 may provide a therapeutic option for the treatment of COVID-19.Gang Xu Ying Li Shengyuan Zhang Haoran Peng Yunyun Wang Dekang Li Taijie Jin Zhuohao He Yilun Tong Chunting Qi Guowei Wu Kangyun Dong Jizhou Gou Yang Liu Tongyang Xiao Jing Qu Liang Li Liang Liu Ping Zhao Zheng Zhang Junying Yuan 2021Cell Research2021,31,12:6
3Chemoselective hydrogenation of phenol to cyclohexanol using heterogenized cobalt oxide catalysts显示文摘Cyclohexanol is an important intermediate in the synthesis of Nylon-6 and plasticizers. In this work,cobalt oxide nanoparticles(NPs) supported on porous carbon(Co O_x@CN) were fabricated by one-pot method and the hybrids could efficiently and selectively hydrogenate phenol to cyclohexanol with a high yield of 98%. The high catalytic performance of Co Ox@CN was associate with the high surface area(340 m^2/g) and uniformly dispersed NPs. Furthurmore, by detailed analysing the relationship between catalytic activity and catalysts composition, it clearly indicated that the Co_3O_4 in Co Ox@CN played an important role for the adsorption and activation of phenol and the in situ gernerated Co was responsible for hydrogen adsorption and dissociation. These findings provide a fundamental insight into the real active sites in hydrogenation of phenol using Co-based catalysts.Zhongzhe Wei Yi Li Jing Wang Haoran Li Yong Wang 2018Chinese Chemical Letters2018,29,6:4
4Numerical simulation of nonlinear propagation of sound waves in a finite horn显示文摘Nonlinear acoustic propagation generated by a piston in a finite horn is numerically studied.A quasi-one-dimensional nonlinear model with varying cross-section uses high-order low-dispersion numerical schemes to solve the governing equation.Because of the nonlinear wave distortion and reflected sound waves at the mouth,broadband time-domain impedance boundary conditions are employed.The impedance approximation can be optimized to identify the complex-conjugate pole-residue pairs of the impedance functions,which can be calculated by fast and efficient recursive convolution.The numerical results agree very well with experimental data in the situations of weak nonlinear wave propagation in an exponential horn,it is shown that the model can describe the broadband characteristics caused by nonlinear distortion.Moreover,finite-amplitude acoustic propagation in types of horns is simulated,including hyperbolic,conical,exponential and sinusoidal horns.It is found that sound pressure levels at the horn mouth are strongly affected by the horn profiles,the driving velocity and frequency of the piston.The paper also discusses the influence of the horn geometry on nonlinear waveform distortion.HOU Wei PAN Haoran SONG Weihua JING Xiaodong SUN Xiaofeng 2015Chinese Journal of Acoustics2015,34,2:4
5Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver显示文摘Obesity is a major risk factor for cancers including hepatocellular carcinoma(HCC)that develops from a background of non-alcoholic fatty liver disease(NAFLD).Hypercholesterolemia is a common comorbidity of obesity.Although cholesterol biosynthesis mainly occurs in the liver,its role in HCC development of obese people remains obscure.Using high-fat high-carbohydrate diet-associated orthotopic and spontaneous NAFLD-HCC mouse models,we found that hepatic cholesterol accumulation in obesity selectively suppressed natural killer T(NKT)cell-mediated antitumor immunosurveillance.Transcriptome analysis of human liver revealed aberrant cholesterol metabolism and NKT cell dysfunction in NAFLD patients.Notably,cholesterol-lowering rosuvastatin restored NKT expansion and cytotoxicity to prevent obesogenic diet-promoted HCC development.Moreover,suppression of hepatic cholesterol biosynthesis by a mammalian target of rapamycin(mTOR)inhibitor vistusertib preceded tumor regression,which was abolished by NKT inactivation but not CD8^(+)T cell depletion.Mechanistically,sterol regulatory element-binding protein 2(SREBP2)-driven excessive cholesterol production from hepatocytes induced lipid peroxide accumulation and deficient cytotoxicity in NKT cells,which were supported by findings in people with obesity,NAFLD and NAFLD-HCC.This study highlights mTORC1/SREBP2/cholesterol-mediated NKT dysfunction in the tumor-promoting NAFLD liver microenvironment,providing intervention strategies that invigorating NKT cells to control HCC in the obesity epidemic.Wenshu Tang Jingying Zhou Weiqin Yang Yu Feng Haoran Wu Myth T.S.Mok Lingyun Zhang Zhixian Liang Xiaoyu Liu Zhewen Xiong Xuezhen Zeng Jing Wang Jiahuan Lu Jingqing Li Hanyong Sun Xiaoyu Tian Philip Chun Yeung Yong Hou Heung Man Lee Candice C.H.Lam Howard H.W.Leung Anthony W.H.Chan Ka Fai To John Wong Paul B.S.Lai Kelvin K.C.Ng Simon K.H.Wong Vincent W.S.Wong Alice P.S.Kong Joseph J.Y.Sung Alfred S.L.Cheng 2022Cellular & Molecular Immunology2022,19,7:3
6A high-performance Mg-4.9Gd-3.2Y-1.1Zn-0.5Zr alloy via multidirectional forging after analyzing its compression behavior显示文摘A high-performance Mg-4.9Gd-3.2Y-1.1Zn-0.5Zr alloy has been fabricated by multidirectional forging(MDF)after analyzing its compression behavior.The as-homogenized alloy exhibits a high activation energy Q of deformation(~285 kJ/mol).The size of DRXed grains after compression tends to decrease as the Z-H parameter(Z)increases,showing a grain size exponent m of~4.0.Lamellar LPSO phases,kinking deformation,and bimodal microstructure are detected at the relatively low compression temperature of 350 and 400℃,while sufficient DRX can be achieved at 500℃,accompanied by the dissolution of lamellar LPSO.According to the processing maps,MDF was successfully conducted under an appropriate condition.After peak-aged at 200℃for 78 h,the MDFed billet exhibits a tensile yield strength(TYS)of 331 and 305 MPa at room temperature and 200℃,respectively.The high strength mainly results from the combination of fine grains,low Schmid factor for basal slip,sufficientβ’ageing precipitates,and directionally arranged interdendritic LPSO phases,etc.This paper provides a feasible way for the fabrication of high-performance,low-RE-content,and large-scale Mg components for industrial production.Xiaojie Zhou Yuan Yao Jian Zhang Xiaomin Chen Weiying Huang Jing Pan Haoran Wang Maopeng Weng 2021Journal of Materials Science & Technology2021,,11:3
7Controlled synthesis of core-mesoporous shell from biomass sustainable N-doped hollow carbonaceous nanospheres显示文摘Chuanlong Han Shiping Wang Jing Wang Mingming Li Jiang Deng Haoran Li YongWang 2014Nano Research2014,7,12:3
8Microfluidic chips for the endothelial biomechanics and mechanobiology of the vascular system显示文摘Endothelial cells arranged on the vessel lumen are constantly stimulated by blood flow,blood pressure and pressureinduced cyclic stretch.These stimuli are sensed through mechanical sensory structures and converted into a series of functional responses through mechanotransduction pathways.The process will eventually affect vascular health.Therefore,there has been an urgent need to establish in vitro endothelial biomechanics and mechanobiology of models,which reproduce three-dimensional structure vascular system.In recent years,the rapid development in microfluidic technology makes it possible to replicate the key structural and functionally biomechanical characteristics of vessels.Here,we summarized the progress of microfluidic chips used for the investigation of endothelial biomechanics and mechanobiology of the vascular system.Firstly,we elucidated the contribution of shear stress and circumferential stress,to vascular physiology.Then,we reviewed some applications using microfluidic technology in angiogenesis and vasculogenesis,endothelial permeability and mechanotransduction,as well as the blood-brain barrier under these physical forces.Finally,we discussed the future obstacles in terms of the development and application of microfluidic vascular chips.HAORAN SU KEXIN LI XIAO LIU JING DU LI WANG XIAOYAN DENG YUBO FAN 2021BIOCELL2021,45,4:2
9Phase transferring luminescent gold nanoclusters via single-stranded DNA显示文摘Atomically precise gold nanoclusters(Au NCs) are an emerging class of quantum-sized nanomaterials with discrete electronic energy levels, which has led to a range of attractive electronic and optical applications. Nevertheless, the lack of general methods to transfer Au NCs protected with hydrophobic ligands to an aqueous solution hampers their use in physiological settings. Here,we developed a single-stranded DNA-based approach that could transfer ~90% hydrophobic Au NCs into an aqueous solution.We experimentally and theoretically established that multivalent electrostatic and hydrophobic interactions between DNA strands and the hydrophobic ligand layer on Au NCs resulted in monodispersed DNA-coated Au NCs with high physical integrity in an aqueous solution. The fluorescence quantum yield of Au NCs was increased by ~13 fold, and surface-constrained DNA retained the specific recognition ability for biosensing. We further demonstrated the versatility of this phase-transfer approach, which thus holds great potential to advance biological and medical applications of Au NCs.Yu Li Hui Lu Zhibei Qu Mingqiang Li Haoran Zheng Peilin Gu Jiye Shi Jiang Li Qian Li Lihua Wang Jing Chen Chunhai Fan Jianlei Shen 2022Science China Chemistry2022,65,6:1
10Peripheral body temperature rhythm is associated with suicide risk in major depressive disorder:a case-control study显示文摘Background Patients with major depressive disorder(MDD)may have an abnormal peripheral body temperature rhythm,but its relationship with suicidal risk and the response to treatment with antidepressants remain unknown.Aims This study aimed to investigate the feature of peripheral body temperature in patients with MDD and its relationship with suicide risk before and after treatment with antidepressants.Methods This is a prospective case-control study.Patients diagnosed as MDD were enrolled into MDD group.Healthy subjects who matched in terms of gender,age and body mass index were enrolled into normal control(NC)group.The 24-hour peripheral body temperatures were monitored by TM’Holter the next day after assessment.Patients with MDD were re-assessed after a 2-week treatment with antidepressants.All temperature data were fitted into cosine curves by Python.Result There were 41 patients with MDD,and 21 NC participants enrolled and completed the baseline assessments before the treatment.Patients with MDD were further divided into subgroup of with suicide risk or without suicide risk.In patients with MDD,the mesor of peripheral body temperature rhythm was higher in both patients with(36.17(0.30))and without suicide risk(36.22(0.27))than the mesor in NC participants before treatment(35.84(0.38),Z=11.82,p=0.003,Kruskal-Wallis test).The phase-delay of temperature before treatment was greater in patients with MDD with suicidal risk(4.71(1.68))in comparison with those without suicidal risk(3.05(2.19))and NC participants(3.19(1.82),Z=9.68,p=0.008,Kruskal-Wallis test).Moreover,phase-delay of temperature was associated with suicide risk in patients with MDD before treatment(OR=1.046,95%CI:1.009 to 1.085,p=0.015,unadjusted;OR=1.080,95%CI:1.020 to 1.144,p=0.009,adjusted by age and sex).Conclusion Patients with MDD might have abnormal peripheral body temperature.The abnormal phase-delay of peripheral body temperature may indicate suicide risk in patients with MDD,depending on validation in large-scale cohorts.Xin Ma Jing Cao Hailin Zheng Xinchun Mei Meijuan Wang Haoran Wang Yu Shuai Yuan Shen 2021General Psychiatry2021,34,1:1
11Waste pulp chemical-looping gasification using Ni-modified electroplating sludge as an oxygen carrier显示文摘Waste pulp(WP)is a typical byproduct of paper industry,and Chemical-looping gasification(CLG)as a recently developed technology is highly suited to dispose high-volatile wastes like WP.In order to make a high-efficiency oxygen carrier(OC)for CLG of WP,the Ni-containing electroplating sludge(NES)was used as the matrix and NiO modification was performed to enhance the hydrogen production in CLG.These resulted in a potentially high-efficiency OC denoted as NNES.Testing CLG of WP was in a fixed-bed reactor at 850℃by adopting NNES as the OC,injecting 2.4 mL/g(WP)water,and keeping a mass ratio of 1.0 between OC to WP.It produced 1.73 Nm^(3)/kg syngas that has an LHV of 11.9 MJ/Nm^(3)and a H_(2)/CO ratio of 3.63.In 10 redox cycles,the syngas yield did not have obvious decrease,but a certain reduction in the activity of NNES was observed.Characterization of the spent NNES revealed that it is the Ni agglomeration and inert silicate generation which reduced the activity of NNES.Genyang Tang Jing Gu Guoqiang Wei Haoran Yuan Yong Chen 2023Carbon Resources Conversion2023,6,2:1
12A novel blue-purple Ce^(3+) doped whitlockite phosphor:Synthesis,crystal structure,and photoluminescence properties显示文摘At present,the rare earth(RE) ions doped phosphors have attracted more and more attention because of their excellent properties.In this paper,a series of novel blue-purple β-Ca_(3)(PO_(4))_(2):Ce^(3+) phosphors were synthesized by a high temperature solid phase method.The X-ray diffraction(XRD),infrared spectrum,energy dispersive spectroscopy(EDS),scanning electron microscopy(SEM),X-ray photoelectron spectroscopy(XPS),photoluminescence excitation and emission spectra were used to investigate the crystal structure,composition and the luminescent properties of the resulting samples.The phosphor shows a strong absorption in the ultraviolet band.Under the excitation of 269 nm,the phosphor emits a strong purple fluorescence ranging from 360 to 520 nm.When Ce^(3+) doping content is 0.07 mol,the strongest luminescence intensity is reached,and the concentration quenching mechanism is dipole-dipole(d-d)interaction for Ce^(3+) based on Dexter theory.Yuli Yuan Haoran Lin Jing'ao Cao Qingfeng Guo Fei Xu Libing Liao Lefu Mei 2021Journal of Rare Earths2021,39,6:1
13High Temperature Creep behaviour of a Si_3N_4 Whisker Reinforced Al-Fe-V-Si Composite显示文摘The creep behaviour of β-Si3N4 whisker reinforced Al-8.5Fe-1.3V-1.7Si composite has been investigated at the temperature 773 and 823 K. The results are characterized by high stress exponent and high apparent creep activation energy The creep data can be interpreted based on the incorporation of a threshold Stress and a load transfer coefficient into the power-law creep equation. A good correlation between the normalized creep rate and normalized effective stress is available which demonstrates that the creep behaviour of both the alloy and the composite is controlled by the matrix lattice self-diffusion in AI. EXamination on microstructure shows that edge dislocations exist at the interfaces between two adjacent whiskers and the intedeces emit edge dislocations in parallel paired-columns.Liangming PENG Shijie ZHU Haoran CHEN and Fugang WANG(Dept. of Materials Engineering,Dalian University of Technology, Dalian 116023, China)Zongyi MA and Jing BI(Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China) 1998Journal of Materials Science & Technology1998,14,6:0
14Research on Digital and Analog Electronic Experiment Teaching Course Management based on UltraLab Network Experiment Platform显示文摘Digital circuit and analog circuit courses are basic courses for students of science and engineering universities. Among them,the practical courses are of great significance for students to master the knowledge of electronics. In order to make teachers teaching more efficiently and students studying more quickly,how to update the experimental course in teaching reform is the key point. This paper analyzing the present situation of teaching in the digital circuit and analog circuit courses,the teaching questions in universities. On the basis of it,the innovation measures of experimental teaching methods and contents are discussed. Our school tries to introduce the UltraLab network experiment platform,reform and optimize the teaching methods of related courses.And it' s accelerating the construction and development of emerging engineering education' s process,reducing effectively the teacher's time for managing in equipment,improving the students' ability to use instruments.FAN Yiqiang ZHANG Jing YU Haoran HE Guannan YUAN Hongfang 2018International Journal of Plant Engineering and Management2018,23,4:0
15Spatial-temporal distribution and geochemistry of highly evolved Mesozoic granites in Great Xing’an Range,NE China:Discriminant criteria and geological significance显示文摘Highly evolved granite is an important sign of the mature continent crust and closely associated with deposits of rare metals.In this work,the authors undertake systematically zircon U-Pb ages and whole rock elemental data for highly evolved granitic intrusions from the Great Xing’an Range(GXR),NE China,to elucidate their discriminant criteria,spatial-temporal distribution,differentiation and geodynamic mecha-nism.Geochemical data of these highly evolved granites suggest that high w(SiO_(2))(>70%)and differentiation index(DI>88)could be quantified indicators,while strong Eu depletion,high TE_(1,3),lowΣREE and low Zr/Hf,Nb/Ta,K/Rb could only be qualitative indicators.Zircon U-Pb ages suggest that the highly evolved gran-ites in the GXR were mainly formed in Late Mesozoic,which can be divided into two major stages:Late Ju-rassic-early Early Cretaceous(162-136 Ma,peak at 138 Ma),and late Early Cretaceous(136-106 Ma,peak at 126 Ma).The highly evolved granites are mainly distributed in the central-southern GXR,and display a weakly trend of getting younger from northwest to southeast,meanwhile indicating the metallogenic potential of rare metals within the central GXR.The spatial-temporal distribution,combined with regional geological data,indicates the highly evolved Mesozoic granites in the GXR were emplaced in an extensional environ-ment,of which the Late Jurassic-early Early Cretaceous extension was related to the closure of the Mongol-Okhotsk Ocean and roll-back of the Paleo-Pacific Plate,while the late Early Cretaceous extension was mainly related to the roll-back of the Paleo-Pacific Plate.WU Haoran YANG Hao GE Wenchun JI Zheng DONG Yu JING Yan JING Jiahao 2024Global Geology2024,27,1:0
16Structural formation and evolution mechanisms of fracture plugging zone显示文摘A coupled CFD-DEM method is used to simulate the formation process of fracture plugging zone.A photo-elastic system characterizing mesoscale force chain network developed by our own is used to model the pressure evolution in fracture plugging zone to reveal the evolution mechanism of the structure of fracture plugging zone.A theoretical basis is provided for improving the lost circulation control effect in fractured reservoirs and novel methods are proposed for selecting loss control materials and designing loss control formula.CFD-DEM simulation results show that bridging probability is the key factor determining the formation of fracture plugging zone and fracture plugging efficiency.Critical and absolute bridging concentrations are proposed as the key indexes for loss control formula design.With the increase of absolute bridging concentration,the governing factor of bridging is changed from material grain size to the combination of material grain size and friction force.Results of photo-elastic experiments show that mesoscale force chain network is the intrinsic factor affecting the evolution of pressure exerting on the fracture plugging zone and determines the macroscopic strength of fracture plugging zone.Performance parameters of loss control material affect the force chain network structure and the ratio of stronger force chain,and further impact the stability and strength of fracture plugging zone.Based on the study results,the loss control formula is optimized and new-type loss control material is designed.Laboratory experiments results show that the fracture plugging efficiency and strength is effectively improved.XU Chengyuan ZHANG Jingyi KANG Yili XU Feng LIN Chong YAN Xiaopeng JING Haoran SHANG Xiangyu 2021Petroleum Exploration and Development2021,48,1:0
17Regularized focusing inversion for large-scale gravity data based on GPU parallel computing显示文摘Processing large-scale 3-D gravity data is an important topic in geophysics field. Many existing inversion methods lack the competence of processing massive data and practical application capacity. This study proposes the application of GPU parallel processing technology to the focusing inversion method, aiming at improving the inversion accuracy while speeding up calculation and reducing the memory consumption, thus obtaining the fast and reliable inversion results for large complex model. In this paper, equivalent storage of geometric trellis is used to calculate the sensitivity matrix, and the inversion is based on GPU parallel computing technology. The parallel computing program that is optimized by reducing data transfer, access restrictions and instruction restrictions as well as latency hiding greatly reduces the memory usage, speeds up the calculation, and makes the fast inversion of large models possible. By comparing and analyzing the computing speed of traditional single thread CPU method and CUDA-based GPU parallel technology, the excellent acceleration performance of GPU parallel computing is verified, which provides ideas for practical application of some theoretical inversion methods restricted by computing speed and computer memory. The model test verifies that the focusing inversion method can overcome the problem of severe skin effect and ambiguity of geological body boundary. Moreover, the increase of the model cells and inversion data can more clearly depict the boundary position of the abnormal body and delineate its specific shape.WANG Haoran DING Yidan LI Feida LI Jing 2019Global Geology2019,22,3:0
18Local-to-Global Causal Reasoning for Cross-Document Relation Extraction显示文摘Cross-document relation extraction(RE),as an extension of information extraction,requires integrating information from multiple documents retrieved from open domains with a large number of irrelevant or confusing noisy texts.Previous studies focus on the attention mechanism to construct the connection between different text features through semantic similarity.However,similarity-based methods cannot distinguish valid information from highly similar retrieved documents well.How to design an effective algorithm to implement aggregated reasoning in confusing information with similar features still remains an open issue.To address this problem,we design a novel local-toglobal causal reasoning(LGCR)network for cross-document RE,which enables efficient distinguishing,filtering and global reasoning on complex information from a causal perspective.Specifically,we propose a local causal estimation algorithm to estimate the causal effect,which is the first trial to use the causal reasoning independent of feature similarity to distinguish between confusing and valid information in cross-document RE.Furthermore,based on the causal effect,we propose a causality guided global reasoning algorithm to filter the confusing information and achieve global reasoning.Experimental results under the closed and the open settings of the large-scale dataset Cod RED demonstrate our LGCR network significantly outperforms the state-ofthe-art methods and validate the effectiveness of causal reasoning in confusing information processing.Haoran Wu Xiuyi Chen Zefa Hu Jing Shi Shuang Xu Bo Xu 2023IEEE/CAA Journal of Automatica Sinica2023,10,7:0
19Inhibition of the Neddylation Pathway Suppresses Enterovirus Replication显示文摘Dear Editor,Human enteroviruses(HEVs)comprise polioviruses,coxsackieviruses,echoviruses,rhinoviruses,and the enterovirus subgroups and belong to the genus Enterovirus in the family Picornaviridae(Baggen et al.2018).The HEV genome was thought to contain a single open reading frame(ORF)encoding one polyprotein,which was post-translationally processed into structural capsid proteins(VP1-4)and non-structural accessory proteins(2A,2B,2C,3A,3B,3C,3D)(Baggen et al.2018).Recently,we and others,have identified an additional upstream ORF(Guo et al.2019a;Lulla et al.2019)(ORF2/uORF).Zhe Zhang Haoran Guo Jing Wang Yan Li Yanhang Gao Quan Liu Junqi Niu Wei Wei 2021Virologica Sinica2021,36,6:0
20Development of sustainable and efficient recycling technology for spent Li-ion batteries: Traditional and transformation go hand in hand显示文摘Clean and efficient recycling of spent lithium-ion batteries(LIBs)has become an urgent need to promote sustainable and rapid development of human society.Therefore,we provide a critical and comprehensive overview of the various technologies for recycling spent LIBs,starting with lithium-ion power batteries.Recent research on raw material collection,metallurgical recovery,separation and purification is highlighted,particularly in terms of all aspects of economic efficiency,energy consumption,technology transformation and policy management.Mechanisms and pathways for transformative full-component recovery of spent LIBs are explored,revealing a clean and efficient closed-loop recovery mechanism.Optimization methods are proposed for future recycling technologies,with a focus on how future research directions can be industrialized.Ultimately,based on life-cycle assessment,the challenges of future recycling are revealed from the LIBs supply chain and stability of the supply chain of the new energy battery industry to provide an outlook on clean and efficient short process recycling technologies.This work is designed to support the sustainable development of the new energy power industry,to help meet the needs of global decarbonization strategies and to respond to the major needs of industrialized recycling.Zejian Liu Gongqi Liu Leilei Cheng Jing Gu Haoran Yuan Yong Chen Yufeng Wu 2024Green Energy & Environment2024,9,5:0
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