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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 2 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 3 | 二甲双胍长期治疗2型糖尿病患者以及维生素B12缺乏的危险性:随机安慰剂对照研究(摘要)显示文摘目的 研究接受胰岛素治疗的2型糖尿病患者中,二甲双胍所致维生素B12缺乏(〈150pmol/L)、低浓度维生素B12(150—220pmol/L)的发生率,以及叶酸和同型半胱氨酸的浓度。 | Jolien de Jager Adriaan Kooy Philippe Lehert Michiel G Wulffele Jan van der Kolk Daniel Bets Joop Verburg Ab J M Donker Coen D A Stehouwer 许翎岭(译) | 2010 | 英国医学杂志中文版2010，13，5： | 2 |
| 4 | Pancreatic Enzyme Replacement Therapy in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis: A 1-Year Disease Management Study on Symptom Control and Quality of Life显示文摘 | Jan G. D’Haese Güralp O. Ceyhan Ihsan Ekin Demir Peter Layer Waldemar Uhl Matthias L?hr Reinhard Rychlik Konstantinos Pirilis York Z?llner Birgit Gradl Douglas Foerster Julia M?bius Friederike Henniges Helmut Friess | 2014 | Pancreas2014，，： | 2 |
| 5 | High-dose conformal radiotherapy for treatment of stage ⅢA/ⅢB non-small cell lung cancer: technical issue and results of a phase Ⅰ/Ⅱ trial 显示文摘 | Julian G Rosenman M Jan S | 2002 | Int J Radiat Oncol Biol Phys2002，54，： | 1 |
| 6 | Preparation and properties of zirconia-toughened mullite ceramics 显示文摘 | YUAN Q M JAN J Q JIN Z G | 1986 | J Am Ceram Soc1986，69，3： | 1 |
| 7 | PRISMA-DB A parallel main memory relational DBMS 显示文摘 | PETER M G A CAREL A V D B JAN F | 1992 | IEEE Transactions on Knowledge and Data Engineering1992，4，6： | 1 |
| 8 | Explaining the acceptance and use of government Internet services: A multivariate analysis of 2006Survey data in the Netherlands显示文摘 | Jan A G Dijk M van Peters O | 2008 | Government Information Quarterly2008，25，3： | 1 |
| 9 | Effect of particle size of chemical mechanical polishing slurries for enhanced polishing with minimal defects显示文摘 | Basim G B A dler J J M aha Jan U | 2000 | Elecrochem Soc2000，147，35： | 1 |
| 10 | Van Mier (2008) on Flow Oroperties, Fibre Distribution, Fibre Orientation and Flexural Behaviour of FRC显示文摘 | Patrick Stahli Rocco Custer Jan G M | 2008 | Materials and Structures2008，41，： | 1 |
| 11 | Synthesis, Characteriza- tion,and Applications of the New Zeolite UZM-5显示文摘 | Jan D Y Lewis G J Mezza T M | 2004 | Stud Surf Sci Catal2004，154，： | 1 |
| 12 | Raman spectroscopy as tool for the characterization of thio-polyaromatic hydrocarbons in organic minerals显示文摘 | Otakar F Jan J Howell G M E | 2007 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2007，68，4： | 1 |
| 13 | Development of human protein reference database as an initial platform for approaching systems biology in humans 显示文摘 | PERI S NAVARRO J D AMANCHY R KRISTIANSEN T Z JONNALAGADDA C K SURENDRANATH V NIRAN JAN V MUTHUSAMY B GANDHI T K GRONBORG M IBARROLA N DESHPANDE N SHANKER K SHIVASHANKAR H N RASHMI B P RAMYA M A ZHAO Z CHANDRIKA K N PADMA N HARSHA H C YATISH A J KAVITHA M P MENEZES M CHOUDHURY D R SURESH S GHOSH N SARAVANA R CHANDRAN S KRISHNA S JoY M ANAND S K MADAVAN V JOSEPH A WONG G W SCHIEMANN W P CONSTANTINESCU S N HUANG L KHOSRAVI-FAR R STEEN H TEWARI M GHAFFARI S BLOBE G C DANG C V GARCIA J G PEVSNER J JENSEN O N ROEPSTORFF P DESHPANDE K S CHINNAIYAN A M HAMOSH A CHAKRAVARTI A PANDEY A | 2003 | Genome Research2003，13，10： | 1 |
| 14 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 15 | Pricing policy in nature-based tourism显示文摘 | Jan G Laarman Hans M Gregersen | 1996 | Tourism Management1996，17，4： | 1 |
| 16 | On the Existence of an Optimal Capital Structure: Theory and Evidence显示文摘 | Bradley M Jan'ell G A Kim E H | 1984 | The Journal of Finance1984，39，3： | 1 |
| 17 | Treatment review of sight threatening circumscribed choroidal haemangioma显示文摘AIM:To describe our clinical experience in treating circumscribed choroidal haemangioma(CCH)in a tertiary referral centre over a fifteen year period prior to photodynamic therapy. METHODS:The departmental database and photographic records of a tertiary referral center were used to identify patients who were treated for CCH between 1992 and 2007. Their case records were reviewed. RESULTS:Visual acuity improved(>2 Snellen lines)in eleven patients(69%)remained stable in one patient(6%) and deteriorated in four patients(25%).Six of the seven treated with brachytherapy and three of the four treated with transpupillary thermotherapy achieved better visual acuity after treatment.86%of patients treated within six months of onset of symptoms and 50%of patients treated after six months of onset of symptoms noted an improvement in visual acuity.Only one patient in our series had a final VA of 6/60 or worse.Mean follow-up was thirty-five months. CONCLUSION:Visual outcome is better when treatment is performed within 6 months of symptoms.The majority of patients achieved an improvement in visual acuity without any adverse effect following treatment. | James FT Li Yim Teresa Sandinha Jan M Kerr Diana Ritchie Ewan G Kemp | 2010 | International Journal of Ophthalmology(English edition)2010，3，2： | 1 |
| 18 | Digiml simulation of random processes and its applications显示文摘 | Deodatis G Jan C M | 1972 | Sound and Vibration1972，25，1： | 1 |
| 19 | A New Measure Health Status for Clinical Trials in Inflammatory Bowel Disease显示文摘 | Gordon G Alba M E Jan I | 1989 | Gastroenterology1989，96，： | 1 |
| 20 | Pricing policy in nature-based tourism显示文摘 | Jan G L Hans M G | 1996 | Tourism Management1996，17，4： | 1 |
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