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| 1 | Oral probiotic VSL #3 attenuates the circulatory disturbances of patients with cirrhosis and ascites显示文摘 | Diego Rincón Javier Vaquero Ana Hernando Evelyn Galindo Cristina Ripoll Marta Puerto Magdalena Salcedo Rubén Francés Ana Matilla María V. Catalina Gerardo Clemente José Such Rafael Ba?ares | 2014 | Liver Int2014，，10： | 2 |
| 2 | Liquid Chromatographic Determination of Aniline in Table-Top Sweeteners Based on Pre-Column Derivatization with 1,2-Naphthoquinone-4-Sulfonate显示文摘 | David Hernando Javier Saurina Santiago Hemandez- Cassou | 1999 | Journal of Chromatography A1999，859，： | 1 |
| 3 | Coeliac disease screening in first-degree relatives on the basis of biopsy and genetic risk显示文摘 | Luis Vaquero Alberto Caminero Alejandro Nu?ez Mercedes Hernando Cristina Iglesias Javier Casqueiro Santiago Vivas | 2014 | European Journal of Gastroenterology & Hepatology2014，，3： | 1 |
| 4 | Linear Prediction of the OneSided Autoconelation Sequence for Noisy Speech Recognition显示文摘 | Javier Hernando Climent Nadeu | 1997 | IEEE Transactions on Speech and Audio Processing1997，5，1： | 1 |
| 5 | Liquid chromatographic determination of aniline in table-top sweeteners based on pre-column derivatization with 1,2-Naphthoquinone-4-Sulfonate显示文摘 | David Hernando Javier Santiago Hernandez-Cassou | 1999 | J Chromatogr A1999，859，： | 1 |
| 6 | Duodenal biopsy may be avoided when high transglutaminase antibody titers are present显示文摘AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided.METHODS: A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary centers. Human IgA class anti-tTG antibody measurement and upper gastrointestinal endoscopy were performed at diagnosis. A second biopsy was performed in 40 asymptomatic adults on a gluten-free diet (GFD) and with normal tTG levels.RESULTS: Adults showed less severe histopathology (26% vs 63%, P<0.0001) and lower tTG antibody titers than children. Levels of tTG antibody correlated with Marsh type in both populations (r=0.661, P<0.0001). Multiple logistic regression revealed that only tTG antibody was an independent predictor for Marsh type 3 lesions, but clinical presentation type and age were not. A cut-off point of 30 U tTG antibody yielded the highest area under the receiver operating characteristic curve (0.854). Based on the predictive value of this cut-off point, up to 95% of children and 53% of adults would be correctly diagnosed without biopsy. Despite GFDs and decreased tTG antibody levels, 25% of the adults did not recover from villous atrophy during the second year after diagnosis.CONCLUSION: Strongly positive tTG antibody titers might be sufficient for CD diagnosis in children. However, duodenal biopsy cannot be avoided in adults because disease presentation and monitoring are different. | Santiago Vivas Jose G Ruiz de Morales Sabino Riestra Laura Arias Dolores Fuentes Noemi Alvarez Sara Calleja Mercedes Hernando Blanca Herrero Javier Casqueiro Luis Rodrigo | 2009 | World Journal of Gastroenterology2009，15，38： | 1 |
| 7 | Characterising Mycobacterium tuberculosis Rv1510c protein and determining its sequences that specifically bind to two target cell lines显示文摘 | Ricardo Vera-Bravo Elizabeth Torres John J. Valbuena Marisol Ocampo Luis E. Rodríguez álvaro Puentes Javier E. García Hernando Curtidor Jimena Cortés Magnolia Vanegas Zuly J. Rivera Andrea Díaz Martha N. Calderon Manuel A. Patarroyo Manuel E. Patarroyo | 2005 | Biochemical and Biophysical Research Communications2005，，： | 1 |
| 8 | Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion显示文摘 | Víctor Hernando Javier Inserte Carmem Luíza Sartório Víctor M. Parra Marcos Poncelas-Nozal David Garcia-Dorado | 2010 | Journal of Molecular and Cellular Cardiology2010，，2： | 1 |
| 9 | Improving collaborative filtering recommender system results and performance using genetic algorithms显示文摘 | Jesus Bobadilla Fernando Ortega Antonio Hernando Javier Alcalá | 2011 | Knowledge-Based Systems2011，，8： | 1 |
| 10 | Contribution of calpains to myocardial ischaemia/reperfusion injury显示文摘 | Javier Inserte Victor Hernando David Garcia-Dorado | 2012 | Cardiovascular Research2012，，1： | 1 |
| 11 | Liquid Chromatographic Determination of Aniline in Table-Top Sweeteners Based on Pre-Column Derivatization with 1,2-Naphthoquinone-4-Sulfonate 显示文摘 | David Hernando Javier Saurina Santiago HernandezCasso | 1999 | Journal of Chromatography A1999，859，： | 1 |
| 12 | From conventional two-stage hepatectomy to ALPPS:Fifteen years of experience in a hepatobiliary surgery unit显示文摘Background:Hepatectomy in patients with large tumor load may result in postoperative liver failure and associated complications due to excessive liver parenchyma removal.Conventional two-stage hepatectomy(TSH)and associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique are possible solutions to this problem.Colorectal liver metastases(CRLM)is the most frequent indication,and there is a need to assess outcomes for both techniques to improve surgical and long-term oncological outcomes in these patients.Methods:A single-center retrospective study was designed to compare TSH with ALPPS in patients with initially unresectable bilateral liver tumors between January 2005 and January 2020.ALPPS was performed from January 2012 onwards as the technique of choice.Long-term overall survival(OS)and disease-free survival(DFS)were evaluated as primary outcome in CRLM patients.Postoperative morbidity,mortality and liver growth in all patients were also evaluated.Results:A total of 38 staged hepatectomies were performed:17 TSH and 21 ALPPS.Complete resection rate was 76.5%(n=13)in the TSH group and 85.7%(n=18)in the ALPPS group(P=0.426).Overall major morbidity(Clavien-Dindo≥3 a)(stage 1+stage 2)was 41.2%(n=7)in TSH and 33.3%(n=7)in ALPPS patients(P=0.389),and perioperative 90-day mortalities were 11.8%(n=2)vs.19.0%(n=4)in each group,respectively(P=0.654).Intention-to-treat OS rates at 1 and 5 years in CRLM patients for TSH(n=15)were 80%and 33%,and for ALPPS(n=17)76%and 35%,respectively.DFS rates at 1 and 5 years were 36%and 27%in the TSH group vs.33%and 27%in the ALPPS group,respectively.Conclusions:ALPPS is an effective alternative to TSH in bilateral affecting liver tumors,allowing higher resection rate,but patients must be carefully selected.In CRLM patients similar long-term OS and DFS can be achieved with both techniques. | Javier Maupoey Ibáñez Eva María MontalváOrón Andrea BoscàRobledo Alonso Camacho Ramírez Ana Hernando Sanz Pablo Granero Castro Alberto Alegre Delgado Rafael López-Andújar | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，6： | 0 |
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