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| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017,17,27: | 3 |
| 2 | Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction显示文摘 | Jeffrey L Anderson John F Carlquist Joseph B Muhlestein Benjamin D Horne Sidney P Elmer | 1998 | Journal of the American College of Cardiology1998,,1: | 2 |
| 3 | D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation显示文摘AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient. | Jeffrey B Halldorson Robert L Carithers Jr Renuka Bhattacharya Ramasamy Bakthavatsalam Iris W Liou Andre A Dick Jorge D Reyes James D Perkins | 2014 | World Journal of Transplantation2014,4,3: | 2 |
| 4 | ACC/AHA 2007 guidelines for the management of patients with unstable angina/nonSTelevation myocardial infarction:executive summary显示文摘 | JEFFREY L CYNTHIA D ELLIOTT M | 2007 | J Am Coil Car2007,116,: | 1 |
| 5 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012,,10: | 1 |
| 6 | Temozolomideis Active in Childhood, Progressive, Unresectable,Low-Grade Gliomas 显示文摘 | Kuo D J Weiner H L Jeffrey W | 2003 | J Pediatr Hematol Oncol2003,25,5: | 1 |
| 7 | Synthesis and e- valuation of vancomycin and vancomycin aglycon ana- logues that bear modifications in the residue 3 aspargine 显示文摘 | Jeffrey M Steven L C Boger D L | 2002 | Bioorg&Med Chem Left2002,12,9: | 1 |
| 8 | Role of Streptococcus thermophilus MR-1C Capsular Exopolysaccharide in Cheese Moisture retention显示文摘 | DEBORAH L JEFFREY A AHLGREN D H | 1998 | Appl Environ Microbiol1998,64,6: | 1 |
| 9 | Self-assembly combining two bioaetive peptide-amphiphile molecules into nanofihers by electrostatic attraction显示文摘 | KRISTA L NIECE JEFFREY D | 2003 | J Am Chern Soc2003,125,24: | 1 |
| 10 | Ocean PHILLS hyperspectral imager: design, characterization, and calibration显示文摘 | Curtiss D O Jeffrey B Robert L A | 2002 | Optics express2002,10,4: | 1 |
| 11 | Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors显示文摘 | Jeffrey P D Tong L Pavletich N P | 2000 | Gene Deve2000,14,24: | 1 |
| 12 | Novel high-gain,improved-bandwidth,finned-ladder V-band and traveling-wave tube slow-wave circuit design显示文摘 | Carol L Kory Jeffrey D | 1995 | IEEE Trans Electron Devices1995,9,42: | 1 |
| 13 | Preventable anesthesia mishaps: A study of human factors 显示文摘 | Jeffrey B C Ronald S N Charlene D L | 2002 | Quality & Safety in Health Care2002,,11: | 1 |
| 14 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012,,10: | 1 |
| 15 | The Critical Importance of Retrieval for Learning 显示文摘 | Jeffrey D Karpicke Henry L Roediger | 2008 | Sci- ence2008,,3: | 1 |
| 16 | Highly efficient endogenous human gene correction using designed zinc-finger nucleases显示文摘 | JEFFREY C M YA-Li L | 2005 | Nature2005,,35: | 1 |
| 17 | Desiccation tolerance in the moss Polytrichum formosum : Physiological and fine-structural changes during desiccation and recovery显示文摘 | Michael C F P Roberto L Jeffrey G D | 2007 | Annals of Botany2007,99,: | 1 |
| 18 | female and male sport fans:A comparison of sport consumption motives显示文摘 | Jeffrey D James Lynn L Ridinger | 2002 | Journal of Sport Behavior2002,25,3: | 1 |
| 19 | Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease and Their Relation to Disease Type and Severity显示文摘 | Jennifer L Dotson Jeffrey S Hyams James Markowitz Neal S LeLeiko David R Mack Jonathan S Evans Marian D Pfefferkorn Anne M Griffiths Anthony R Otley Athos Bousvaros Subra Kugathasan Joel R Rosh David Keljo Ryan S Carvalho Gitit Tomer Petar Mamula Marsha H | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010,,2: | 1 |
| 20 | A brief reirvw of ammonia and 'pH' factors 显示文摘 | MICAEL D KLANS L JEFFREY I S | 2000 | Beitr Tabsk2000,19,6: | 1 |