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| 1 | Tailoring strength-ductility balance of caliber-rolled AZ31 Mg alloy through subsequent annealing显示文摘Recently,multi-pass caliber rolling has been shown to be effective for Mg alloys.This study investigated the effect of subsequent annealing on the mechanical properties of a caliber-rolled AZ31 Mg alloy to modulate the strength-ductility relationship.This annealing gave rise to different trends in mechanical properties depending on the temperature regime.Low-temperature annealing(T≤473 K)exhibited a typical trade-off relationship,where an increase in annealing temperature resulted in increased ductility but decreased strength and hardness.Such a heat treatment did not degrade the high strength-ductility balance of the caliber-rolled alloy,suggesting that the mechanical properties could be tailored for different potential applications.In contrast,high-temperature annealing(T>473 K)caused a simultaneous deterioration in strength,hardness,and ductility with increasing annealing temperature.These differences are discussed in terms of the varying microstructural features under the different investigated annealing regimes. | Taein Kong Byung Je Kwak Jonghyun Kim Jeong Hun Lee Sung Hyuk Park Ji Hoon Kim Young Hoon Moon Hyun Sik Yoon Taekyung Lee | 2020 | Journal of Magnesium and Alloys2020，8，1： | 10 |
| 2 | Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment显示文摘 | Jae‐Hyun Park Sang Won Seo Changsoo Kim Geon Ha Kim Hyun Jin Noh Sung Tae Kim Ki‐Chang Kwak Uicheul Yoon Jong Min Lee Jong Weon Lee Ji Soo Shin Chi Hun Kim Young Noh Hanna Cho Hee Jin Kim Cindy W. Yoon Seung Jun Oh Jae Seung Kim Yearn Seong Choe Kyung‐Han | 2013 | Ann Neurol2013，，5： | 1 |
| 3 | Characteristic of interactions between intrathecal gabapentin and either clonidine or neostigmine in the formalin test 显示文摘 | Yoon MH Choi JI Kwak SH | 2004 | Anesth Analg2004，98，5： | 1 |
| 4 | Method validation for simultaneous determination of chromium, molybdenum and selenium in infant formulas by ICP-OES and ICP-MS显示文摘 | Naeem Khan In Seon Jeong In Min Hwang Jae Sung Kim Sung Hwa Choi Eun Yeong Nho Ji Yeon Choi Byung-Man Kwak Jang-Hyuk Ahn Taehyung Yoon Kyong Su Kim | 2013 | Food Chemistry2013，，4： | 1 |
| 5 | Ectopic peritoneal paragonimiasis mimicking tuberculous peritonitis:A care report显示文摘BACKGROUND The most common site of paragonimiasis is in the lungs.The migratory route passes through the duodenal wall,peritoneum,and diaphragm to the lungs;thus,the thoracic cavity and central nervous system,as well as the liver,intestine,and abdominal cavity may be involved.Here,we present a case of intraperitoneal paragonimiasis without other organ involvement,mimicking tuberculous peritonitis.CASE SUMMARY A 57-year-old man presented with recurrent abdominal pain for 4 wk.Physical examination revealed tenderness in the right lower quadrant.Laboratory findings showed complete blood counts within the normal range without eosinophilia.Multiple reactive lymph nodes and diffuse peritoneal infiltration were noted on abdominal computed tomography(CT).There were no abnormalities on chest CT or colonoscopy.Intraoperative findings of diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis included multiple small whitish nodules and an abscess in the peritoneum.Pathological reports confirmed the presence of numerous eggs of Paragonimus westermani(P.westermani).A postoperative serum enzyme-linked immunosorbent assay revealed P.westermani positivity.Persistent and repetitive history-taking led him to retrospectively recall the consumption of freshwater crab.After 3 d of treatment with praziquantel(1800 mg;25 mg/kg),he recovered from all symptoms.CONCLUSION In patients who require diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis,repetitive history-taking and preoperative serologic antibody tests against Paragonimus may be helpful in diagnosing intraperitoneal paragonimiasis without other organ involvement. | Jung Woo Choi Chang Min Lee Seong Je Kim Se In Hah Ji Yoon Kwak Hyun Chin Cho Chang Yoon Ha Woon Tae Jung Ok Jae Lee | 2022 | World Journal of Clinical Cases2022，10，16： | 0 |
| 6 | Real-world outcomes of ibrutinib therapy in Korean patients with relapsed or refractory mantle cell lymphoma:amulticenter,retrospective analysis显示文摘Dear Editor,Despite the introduction of novel front-line therapies including rituximab plus high-dose cytarabine followed by consolidative autologous stem cell transplantation(ASCT)and salvage therapy with bendamustine,lenalidomide or bortezomib,mantle cell lymphoma(MCL)is still considered incurable and most patients experience relapse or refractory(RR)disease. | Jun Ho Yi Seok Jin Kim Dok Hyun Yoon Cheolwon Suh Myung Hee Chang Deok Hwan Yang Jae-Cheol Jo Shin Young Hyun Hyeon-Seok Eom Jeong-Ok Lee Ji Hyun Kwon Sang Hoon Han Seung-Shin Lee Jae-Yong Kwak Se Hyung Kim Dae Sik Kim Ji Hyun Lee Sung Yong Oh Hun Mo Ryoo Hyo Jung Kim Won Seog Kim | 2021 | Cancer Communications2021，41，3： | 0 |
| 7 | Exosome-guided direct reprogramming of tumor-associated macrophages from protumorigenic to antitumorigenic to fight cancer显示文摘Highly immunosuppressive tumor microenvironment containing various protumoral immune cells accelerates malignant transformation and treatment resistance.In particular,tumor-associated macrophages(TAMs),as the predominant infiltrated immune cells in a tumor,play a pivotal role in regulating the immunosuppressive tumor microenvironment.As a potential therapeutic strategy to counteract TAMs,here we explore an exosome-guided in situ direct reprogramming of tumor-supportive M2-polarized TAMs into tumor-attacking M1-type macrophages.Exosomes derived from M1-type macrophages(M1-Exo)promote a phenotypic switch from anti-inflammatory M2-like TAMs toward pro-inflammatory M1-type macrophages with high conversion efficiency.Reprogrammed M1 macrophages possessing protein-expression profiles similar to those of classically activated M1 macrophages display significantly increased phagocytic function and robust cross-presentation ability,potentiating antitumor immunity surrounding the tumor.Strikingly,these M1-Exo also lead to the conversion of human patient-derived TAMs into M1-like macrophages that highly express MHC class II,offering the clinical potential of autologous and allogeneic exosome-guided direct TAM reprogramming for arming macrophages to join the fight against cancer. | Hyosuk Kim Hyun-Ju Park Hyo Won Chang Ji Hyun Back Su Jin Lee Yae Eun Park Eun Hye Kim Yeonsun Hong Gijung Kwak Ick Chan Kwon Ji Eun Lee Yoon Se Lee Sang Yoon Kim Yoosoo Yang Sun Hwa Kim | 2023 | Bioactive Materials2023，，7： | 0 |
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