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| 1 | Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma显示文摘A previous report has confirmed the existence and clinical significance of vasculogenic mimicry(VM)in glioma.However,its conclusions about the negative clinical significance of VM in glioblastoma are based on a small group of patients and,thus,might be unconvincing.The aim of the present study was to reevaluate the clinical significance of VM in glioblastoma.Patients were classified as VM-positive or | Wang SY Ke YQ Lu GH Song ZH Yu L Xiao S Sun XL Jiang XD Yang ZL Hu CC | 2013 | 中国神经肿瘤杂志2013，11，3： | 22 |
| 2 | Quinone oxidoreductase 1 is overexpressed in gastric cancer and associated with outcome of adjuvant chemotherapy and survival显示文摘BACKGROUND Quinine oxidoreductase 1(NQO1)plays a vital role in protecting normal cells against oxidative damage and electrophilic attack.It is highly expressed in many solid tumors,suggesting a role in cancer development and progression.However,the role of NQO1 in gastric cancer and its effect on cancer development and prognosis have not been fully investigated.AIM To investigate the clinical relevance of NQO1 protein expression in gastric cancer and to explore the potential of NQO1 to serve as a prognostic biomarker and therapeutic target.METHODS In this retrospective study,gastric cancer specimens of 175 patients who were treated between 1995 and 2011 were subjected to immunohistochemistry analyses for NQO1.The correlation of NQO1 expression with gastric cancer prognosis and clinical and pathological parameters was investigated.RESULTS NQO1 protein was overexpressed in 59.43%(104/175)of the analyzed samples.Overexpression of NQO1 was associated with a significantly inferior prognosis.In addition,multivariate analysis suggested that NQO1 overexpression,along with tumor stage and patient age,are prominent prognostic biomarkers for gastric cancer.Moreover,NQO1 overexpression was correlated to a better response to 5-fluorouracil(5-FU)-based adjuvant chemotherapy.CONCLUSION NQO1 overexpression is associated with a significantly poor prognosis and better response to 5-FU in patients with gastric cancer.These findings are relevant for improving therapeutic approaches for gastric cancer patients. | Zhi-Nong Jiang Syed Minhaj Uddin Ahmed Qin-Chuan Wang Hong-Fei Shi Xiu-Wen Tang | 2021 | World Journal of Gastroenterology2021，27，22： | 2 |
| 3 | G protein-coupled receptor kinase5mediates tazarotene-induced gene 1-induced growth suppression of human colon cancer cells显示文摘 | Wu CC Tsai FM Shyu RY Tsai YM Wang CH Jiang SY | 2011 | BMC Cancer2011，11，： | 1 |
| 4 | Chinese expert consensus state- ment on clinical diagnosis and treatment of malignant tumor bone me- tastasis and bone related diseases 显示文摘 | Yu SY Jiang ZF Zhang L | 2010 | Chinese-German Journal of Clinical Oneology January2010，9，： | 1 |
| 5 | Evaluation of renal artery stenosis with hemodymamic parameters of Doppler sonography显示文摘 | Li JC Jiang YX Zhang SY | 2008 | JOURNAL OF VASCULAR SURGERY2008，48，2： | 1 |
| 6 | An esophago-gastric anastomoses with purse string instrument and pro- longed mucosa in continuous 1140 patients with no anstomotic leaking for surgical treatment of esophageal carcinoma 显示文摘 | Zheng SY Chen B Jiang D | 2014 | Dis Esophagus2014，27，1： | 1 |
| 7 | Biochemical mark- ers of agerelated changes in bones turnover and bone mineral density in healthy Chinese men 显示文摘 | Jiang YX Tang SY Wu XP | 2008 | Zhongnan Daxue Xuebao Yixue Ban2008，33，1： | 1 |
| 8 | A distinct AMPK phosphorylation site characterizes cardiac hypertrophy induced by lthyroxine and angiotensin II显示文摘 | Jiang SY Xu M Ma XW | | 0，，09： | 1 |
| 9 | Identification of two critical amino acid res- idues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy 显示文摘 | Qu XX Hao P Song XJ Jiang SM Liu YX Wang PG Rao X Song HD Wang SY Zuo Y Zheng AH Luo M Wang HL Deng F Wang HZ Hu ZH Ding MX Zhao GP Deng HK | 2005 | J Biol Chem2005，280，29： | 1 |
| 10 | Evaluation of renal artery ste nosis with hemodynamic parameters of Doppler sonography显示文摘 | Li JC Jiang YX Zhang SY | 2008 | J Vasc Surg2008，48，2： | 1 |
| 11 | Expression of Beclin-1 in primary salivary adenoid cystic carcinoma and its relation to Bcl-2 and p53 and prognosis显示文摘 | Jiang LC Huang SY Zhang DS | 2014 | Braz J Med Biol Res2014，47，3： | 1 |
| 12 | An investigation of drug-resistant Acinetobacter baumannii infections in a comprehensivehospital of East China 显示文摘 | Zhao SY Jiang DY Xu PC | 2015 | Annals of Clinical Microbiology andAntimicrobials2015，14，： | 1 |
| 13 | Discrimination of the seeds of Notopterygium incisum and Notopterygium franchetii by validated HPLC-DAD-ESI-MS method and principal component analysis显示文摘 | Xu KJ Jiang SY Zhou Y | 2011 | J Pharm Biomed Anal2011，56，5： | 1 |
| 14 | Preoperative transcath- eter arterial chemoembolization and prognosis of patients with hepatocellular carcinomas: retrospective analysis of 120 cases显示文摘 | LU CD PENG SY JIANG XC | 1999 | World J Surg1999，23，3： | 1 |
| 15 | Prospective study of hTERC gene detection by fluorescence in situ hybridization(FISH)in cervical intraepithelial neoplasia 1 natural prognosis显示文摘 | Li L Jiang W Zeng SY | 2014 | European Journal of Gynaecological Oncology2014，35，3： | 1 |
| 16 | The negative feedback regulation of microRNA-146a in human periodontal ligament cells after Porphy- romonas gingivalis lipopolysaccharide stimulation显示文摘 | Jiang SY Xue D Xie YF | 2015 | Inflamm Res2015，64，6： | 1 |
| 17 | A Systematic Literature Review on Risk Factors for Cervical Cancer in Chinese Population显示文摘 | Jiang Y Hu SY Hernandez Donoso L | 2014 | Value Health2014，17，7： | 1 |
| 18 | Revisiting the JPEG - LS prediction scheme 显示文摘 | Jiang J Guo B Yang SY | 2000 | IEEE Proceedings on Vision Image and Signal Processing2000，147，6： | 1 |
| 19 | Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1显示文摘 | Anand Pathak Federica del Monte Wen Zhao Jo-El Schultz John N. Lorenz Ilona Bodi Doug Weiser Harvey Hahn Andrew N. Carr Faisal Syed Nirmala Mavila Leena Jha Jiang Qian Yehia Marreez Guoli Chen Dennis W. McGraw E Kevin Heist J Luis Guerrero Anna A. DePaoli | 2005 | Circulation Research2005，，7： | 1 |
| 20 | Tamoxifen inhibits hepatoma cells growth through an estrogen receptor inde- pendent mechanism显示文摘 | Jiang SY Shyu RY Yeh MY | 1995 | J Hepatol1995，23，6： | 1 |
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