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| 1 | Comparison of mantle-derived matierals from different spatiotemporal settings:Implications for destructive and accretional processes of the North China Craton显示文摘Cratonic destruction or lithospheric thinning beneath North China makes it as one of the most ideal areas for the studying on the formation and evolution of continent. However, the mechanism, time, range and dynamic setting of the destruction, even the lithospheric status before the destruction, are contentious. The comparison among mantle xenoliths in the volcanic rocks from different captured times (e.g. Paleozoic, Mesozoic and Cenozoic) and locations (e.g. intra-plate or its rim, the translithospheric Tanlu fault or the North-South Gravity Line), and peridotitic massifs within the Sulu-Dabie ultrahigh-pressure metamorphism belt along the southern margin of the North China Craton, indicates that (1) the cratonic lithosphere is heterogeneous in structure and composition, and contains mantle weak zones; and (2) the Mesozoic-Cenozoic lithospheric thinning process is complex, including lateral spreading of lithosphere, interaction between melt and peridotite, non-even asthenospheric erosion (huge lithospheric thinning), and the limited lithospheric accretion and thus thickening, which resulted in the final replacement of the refractory cratonic lithosphere by juvenile fertile mantle. In early Mesozoic, the integrity of the North China Craton was interrupted, even destroyed by subduction and collision of the Yangtze block. The mantle wedge of the North China Craton was also metasomatized and modified by melt/fluids revealed from the subducted Yangtze continent. Lithospheric mantle extension and tectonic intrusion of the North China Craton also occurred, accompanied by the asthenospheric upwelling that due to the detachement of the subducted Yangtze continent (orogenic root). During early Cretaceous-early Tertiary, the huge thinning of lithosphere was triggered by the upwelling astheno- sphere due to the subduction of the Pacific plate. Since late Tertiary, the cooling of the upwelling asthenosphere resulted in the replacement of the mantle in existence by the newly accreted lithosphere, accompanied with a little thickness in lithosphere and thus finally achieved the lithospheric thinning as a whole. The translithospheric faults, such as the Tanlu fault, play excellent channels for asthenospheric upwelling. Meanwhile, the channels in lithosphere are usually irregular, which resulted in different eruption times of magma. Peridotite xenolith in the basalts erupted at 100 Ma is mainly fertile, indicating such a fact, that is, the mantle replacement occurred before the eruption (e.g. 125―100 Ma) beneath the eastern part of the North China Craton. | ZHENG JianPing | 2009 | Chinese Science Bulletin2009，54，19： | 45 |
| 2 | 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘象 5-methylcytosine (5mC ) 和 5-hydroxymethylcytosine (5hmC ) 那样的 DNA 修正是知道在哺乳动物影响全球基因表示的 epigenetic 标记。在人的染色体,与基因表示的靠近的关联和高化学的稳定性给他们的流行,这些 DNA epigenetic 标记能为癌症用作理想的 biomarkers 诊断。利用一种高度敏感、选择的化学标记技术,我们这里报导在传播没有房间的 DNA ( cfDNA )并且在从最近与 colorectal 诊断的 260 个病人的一个队收集的配对的肿瘤和邻近的纸巾的 genomic DNA ( gDNA )的 5hmC 的染色体宽的介绍,胃,胰腺,从 90 个健康个人的肝或甲状腺癌症和正常纸巾。5hmC 主要在与开的染色质和容许的 histone 修正重合的 transcriptionally 活跃的区域被散布。柔韧的联系癌症的 5hmC 签名在 cfDNA 被识别为特定的癌症类型是特征的。传播 cfDNA 的 5hmC 底 biomarkers colorectal 和胃的癌症是高度预兆的并且比常规 biomarkers 优异并且比得上从织物活体检视的 5hmC biomarkers。因此,这新策略能从血样品的分析为癌症的诊断和预后导致有效、最低限度地侵略的方法的发展。 | Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu | 2017 | Cell Research2017，27，10： | 30 |
| 3 | Pathways of Influence of the Northern Hemisphere Mid–high Latitudes on East Asian Climate: A Review显示文摘This paper reviews recent progress made by Chinese scientists on the pathways of influence of the Northern Hemisphere mid-high latitudes on East Asian climate within the framework of a“coupled oceanic-atmospheric(land-atmospheric or seaice-atmospheric)bridge”and“chain coupled bridge”.Four major categories of pathways are concentrated upon,as follows:Pathway A—from North Atlantic to East Asia;Pathway B—from the North Pacific to East Asia;Pathway C—from the Arctic to East Asia;and Pathway D—the synergistic effects of the mid-high latitudes and tropics.In addition,definitions of the terms“combined effect”,“synergistic effect”and“antagonistic effect”of two or more factors of influence or processes and their criteria are introduced,so as to objectively investigate those effects in future research. | Jianping LI Fei ZHENG Cheng SUN Juan FENG Jing WANG | 2019 | Advances in Atmospheric Sciences2019，36，9： | 27 |
| 4 | Zircon U-Pb and Hf isotopes of volcanic rocks from the Batamayineishan Formation in the eastern Junggar Basin显示文摘内部结构的研究被进行从 Batamayineishan 形成调查 U-Pb 年龄,踪迹元素和玄武岩的锆石的 Hf 同位素。暗岩从练习井圣罐头被获得 1 在 Junggar 盆以内在东方 Luliang 上高举。跟踪所有样品是 magmatic 的锆石表演的元素数据,与类似的 REE 模式,包括积极 Ce (Ce=5.06134 ) ,而是否定 Eu (Eu=0.06 ? 0.55 ) 在重稀土元素元素的异例和丰富。在 25 谷物之中,一致年龄被细分进三个组;300.4 整潲祺潧整的年龄? | SU YuPing ZHENG JianPing GRIFFIN William L TANG HuaYun O'REILLY Suzanne Y LIN XiangYang | 2010 | Chinese Science Bulletin2010，55，36： | 21 |
| 5 | Subduction and retreating of the western Pacific plate resulted in lithospheric mantle replacement and coupled basin-mountain respond in the North China Craton显示文摘The North China Craton(NCC) witnessed Mesozoic vigorous tectono-thermal activities and transition in the nature of deep lithosphere. These processes took place in three periods:(1) Late Paleozoic to Early Jurassic(~170 Ma);(2) Middle Jurassic to Early Cretaceous(160-140 Ma);(3) Early Cretaceous to Cenozoic(140 Ma to present). The last two stages saw the lithospheric mantle replacement and coupled basin-mountain response within the North China Craton due to subduction and retreating of the Paleo-Pacific plate, and is the emphasis in this paper. In the first period,the subduction and closure of the PaleoAsian Ocean triggered the back-arc extension, syn-collisional compression and then post-collisional extension accompanied by ubiquitous magmatism along the northern margin of the NCC. Similar processes happened in the southern margin of the craton as the subduction of the Paleo-Tethys ocean and collision with the South China Block. These processes had caused the chemical modification and mechanical destruction of the cratonic margins. The margins could serve as conduits for the asthenosphere upwelling and had the priority for magmatism and deformation. The second period saw the closure of the Mongol-Okhotsk ocean and the shear deformation and magmatism induced by the drifting of the Paleo-Pacific slab. The former led to two pulse of N-S trending compression(Episodes A and B of the Yanshan Movement) and thus the pre-existing continental marginal basins were disintegrated into sporadically basin and range pro vince by the Mesozoic magmatic plutons and NE-SW trending faults.With the anticlockwise rotation of the Paleo-Pacific moving direction, the subduction-related magmatism migrated into the inner part of the craton and the Tanlu fault became normal fault from a sinistral one. The NCC thus turned into a back-arc extension setting at the end of this period. In the third period, the refractory subcontinental lithospheric mantle(SCLM) was firstly remarkably eroded and thinned by the subduction-induced asthenospheric upwelling, especially those beneath the weakzones(i.e.,cratonic margins and the lithospheric Tanlu fault zone). Then a slightly lithospheric thickening occurred when the upwelled asthenosphere got cool and transformed to be lithospheric mantle accreted(~125 Ma) beneath the thinned SCLM. Besides, the magmatism continuously moved southeastward and the extensional deformations preferentially developed in weak zones, which include the Early Cenozoic normal fault transformed from the Jurassic thrust in the Trans-North Orogenic Belt, the crustal detachment and the subsidence of Bohai basin caused by the continuous normal strike slip of the Tanlu fault, the Cenozoic graben basins originated from the fault depression in the Trans-North Orogenic Belt, the Bohai Basin and the Sulu Orogenic belt. With small block size, inner lithospheric weak zones and the surrounding subductions/collisions, the Mesozoic NCC was characterized by(1) lithospheric thinning and crustal detachment triggered by the subduction-induced asthenospheric upwelling.Local crustal contraction and orogenesis appeared in the Trans-North Orogenic Belt coupled with the crustal detachment;(2)then upwelled asthenosphere got cool to be newly-accreted lithospheric mantle and crustal grabens and basin subsidence happened, as a result of the subduction zone retreating. Therefore, the subduction and retreating of the western Pacific plate is the outside dynamics which resulted in mantle replacement and coupled basin-mountain respond within the North China Craton. We consider that the Mesozoic decratonization of the North China Craton,or the Yanshan Movement, is a comprehensive consequence of complex geological processes proceeding surrounding and within craton, involving both the deep lithospheric mantle and shallow continental crust. | Jianping ZHENG Hongkun DAI | 2018 | Science China Earth Sciences2018，61，4： | 20 |
| 6 | Assessment of the GPM and TRMM Precipitation Products Using the Rain Gauge Network over the Tibetan Plateau显示文摘Using high-quality hourly observations from national-level ground-based stations, the satellite-based rainfall products from both the Global Precipitation Measurement(GPM) Integrated Multisatellit E Retrievals for GPM(IMERG) and its predecessor, the Tropical Rainfall Measuring Mission(TRMM) Multi-satellite Precipitation Analysis(TMPA), are statistically evaluated over the Tibetan Plateau(TP), with an emphasis on the diurnal variation.The results indicate that:(1) the half-hourly IMERG rainfall product can explicitly describe the diurnal variation over the TP, but with discrepancies in the timing of the greatest precipitation intensity and an overestimation of the maximum rainfall intensity over the whole TP. In addition, the performance of IMERG on the hourly timescale, in terms of the correlation coefficient and relative bias, is different for regions with sea level height below or above 3500 m;(2) the IMERG products, having higher correlation and lower root-mean-square error, perform better than the TMPA products on the daily and monthly timescales; and(3) the detection ability of IMERG is superior to that of TMPA, as corroborated by a higher Hanssen and Kuipers score, a higher probability of detection, a lower false alarm ratio, and a lower bias. Compared to TMPA, the IMERG products ameliorate the overestimation across the TP. In conclusion,GPM IMERG is superior to TRMM TMPA over the TP on multiple timescales. | Sijia ZHANG Donghai WANG Zhengkun QIN Yaoyao ZHENG Jianping GUO | 2018 | Journal of Meteorological Research2018，32，2： | 18 |
| 7 | Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis显示文摘 | Zheng Huifeng Yang Erping Peng Hao Li Jianping Chen Sen Zhou Jianlin Fang Hongsong Qiu Bo Wang Zhe | 2014 | Chinese Medical Journal2014，，22： | 17 |
| 8 | Preparation and Characterization of Three Monoclonal Antibodies against HIV-1 p24 Capsid Protein显示文摘HIV-1 p24 detection provides a means to aid the early diagnosis of HIV-1 infection, track the progression of disease and assess the efficacy of antiretroviral therapy. In the present study, three monoclonal antibodies (mAbs) p3JB9, p5F1 and p6F4 against HIV-1 p24 were generated. All mAbs could detect p24 of HIV-1IIIB, HIV-1Ada-M, HIV-174V mAbs p5F1 and p6F4 could detect HIV-1KM018, while p3JB9 could not. Three mAbs did not react with HIV-2ROD, HIV-2CBL-20 and SIVagmTYO-1. The recognized epitope of p5F1 was located on the Gag amino acid region DCKTILKALGPAATLEEMMTAC. The p5F1 was used to establish a modified sandwich ELISA with rabbit anti-p24 serum and showed good specificity and high sensitivity, which has been used to measure HIV-1 p24 antigen levels in research. | Guangjie Liu Jianping Wang Jianchun Xiao Zhiwei Zhao Yongtang Zheng | 2007 | Cellular & Molecular Immunology2007，4，3： | 14 |
| 9 | Trace-element of Tuoyun cli-nopyroxene:Implication for the deep processes of litho-spheric mantle beneath the southwest Tianshan,West China显示文摘Based on the LAM-ICPMS analytic results on the trace elements of clinopyroxenes in peridotitic xenoliths occurring in early-Cretaceous basalts from western Xinjiang, the properties and the deep processes, including partial melting and mantle metasomatism, of the subcontinental lithospheric mantle beneath the Tuoyun Basin are analyzed. In the northern edge of the Tarim Basin (southwest Tian-shan), the Mesozoic subcontinental lithosphere which has experienced the effect of partial melting (<10%) and intricate mantle metasomatism is characterized by Phanerozoic ’ocean-type’ mantle. The superposed influence of SiO2-un-saturated silicate melt and carbonate melt probably results in the metasomatic medium which resembles the hydrous silicated carbonate melt in some aspects. By comparing Tuoyun mantle with Cenozoic main mantle beneath eastern China, the properties are similar, while the former shows finer grain and higher diopside content of the peridotites and more conspicuous modal metasomatism. | ZHENG Jianping LU Fengxiang S.Y.O’Reilly LUO Zhaohua | 2001 | Chinese Science Bulletin2001，46，14： | 13 |
| 10 | Necking of Q&P Steel during Uniaxial Tensile Test with the Aid of DIC Technique显示文摘A lot of research has been focused on the necking process during the plastic deformation of sheet metals, but the localized necking is rarely distinguished form diffused necking by experiments, due to the limit of measurement equipment and method. Quenching and Partitioning (Q&P) steel is a 3rd generation advanced high strength steel (AHSS). Its good combination of high strength and ductility ensures potential application in automobile industry. Uniaxial tensile tests of QP980 steel sheet at five strain rates are performed to investigate the necking process and the effect of strain rate on necking behavior of Q&P steel. Digital image correlation (DIC) method is applied during tensile tests, and evolutions of major strain, minor strain and normal strain distributions along gauge section of the tensile specimens are obtained. The diffused and localized necking strains are determined according to SWIFT necking theory and HILL necking theory respectively. The test results indicate that with the increasing of strain rate in the investigated range, the diffused necking strain decreases from 0.152 to 0.120 and localized necking strain decreases from 0.245 to 0.137. Meanwhile, the difference of the two strains decreases form 0.096 to 0.017. Thus it can be concluded that strain rate has an influence on both necking strains during the deformation of QP980 steel sheet. Diffused and localized necking strains are determined by uniaxial tensile tests with the aid of DIC technique and the effect of strain rate on necking strains is evaluated. | DING Lei LIN Jianping MIN Junying PANG Zheng YE You | 2013 | Chinese Journal of Mechanical Engineering2013，26，3： | 11 |
| 11 | Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H显示文摘人的 cytosolic NADP-IDH (IDH1 ) 最近被发现了涉及 tumorigenesis。尤其是,到目前为止识别的导出肿瘤的 IDH1 变化主要发生在 Arg132,和变化 R132H 是最流行的。这个变化损害酶的氧化 IDH 活动,但是显示把伪 - ketoglutarate (伪 K G ) 变换成 2-hydroxyglutarate 的新减小功能。这里,我们报导有或没有 isocitrate (ICT ) 的 R132H 变异的 IDH1 的结构跳了。和 mutagenesis 的结构的数据和生物化学的数据揭示一个以前未定义的起始的 ICT 有约束力的状态并且证明那项 IDH 活动要求一个 conformational 变化到一关门预先转移状态。Arg132 在催化反应起多重功能的作用;特别地, R132H 变化从起始的 ICT 有约束力的状态妨碍 conformational 变化到预先转移状态,导致 IDH 活动的缺陷。我们的结果第一次描述那有中间的符合构造,对应于一个起始的 ICT 有约束力的状态并且 R132H 变化能在这符合构造套住酶,因此使潜在地肿瘤镇压的 IDH 活动的鈥渙f f 开关鈥 ? 的分子的机制清楚些。而且,我们为获得的 伪K G 减小活动证明了 Tyr139 的必要性并且建议 Tyr139 可以由从 NADPH 在一个氢化物阴离子的转移期间在 伪K G 的 C2 原子上补偿增加的否定费用到 伪K G 起一个重要作用,它提供新卓见进 鈥渙n 开关鈥?的机制假设地由这个变化的 IDH1 的 oncogenic 减小活动。 | Bei Yang Chen Zhong Yingjie Peng Zheng Lai Jianping Ding | 2010 | Cell Research2010，20，11： | 11 |
| 12 | Structural modal parameter identifi cation and damage diagnosis based on Hilbert-Huang transform显示文摘Traditional modal parameter identifi cation methods have many disadvantages,especially when used for processing nonlinear and non-stationary signals.In addition,they are usually not able to accurately identify the damping ratio and damage.In this study,methods based on the Hilbert-Huang transform(HHT) are investigated for structural modal parameter identifi cation and damage diagnosis.First,mirror extension and prediction via a radial basis function(RBF) neural network are used to restrain the troublesome end-effect issue in empirical mode decomposition(EMD),which is a crucial part of HHT.Then,the approaches based on HHT combined with other techniques,such as the random decrement technique(RDT),natural excitation technique(NExT) and stochastic subspace identifi cation(SSI),are proposed to identify modal parameters of structures.Furthermore,a damage diagnosis method based on the HHT is also proposed.Time-varying instantaneous frequency and instantaneous energy are used to identify the damage evolution of the structure.The relative amplitude of the Hilbert marginal spectrum is used to identify the damage location of the structure.Finally,acceleration records at gauge points from shaking table testing of a 12-story reinforced concrete frame model are taken to validate the proposed approaches.The results show that the proposed approaches based on HHT for modal parameter identifi cation and damage diagnosis are reliable and practical. | Han Jianping Zheng Peijuan Wang Hongtao | 2014 | Earthquake Engineering and Engineering Vibration2014，13，1： | 11 |
| 13 | In situ Re-Os isotope ages of sulfides in Hannuoba peridotitic xenoliths: Significance for the frequently-occurring mantle events beneath the North China Block显示文摘In situ Re-Os isotopes of sulfides in peridotitic xenoliths from Cenozoic Hannuoba basalts were analyzed by LAM-MC-ICPMS. The suifides developed two types of occurrences including silicate-enclosed and interstitial. In the enclosed sulfides, 187Os/188Os vary from 0.1124 to 0.1362 and 187Re/188Os from 0.0026 to 1.8027. In the interstitial ones, 187Os/188Os have a range from 0.1174 to 0.1354 and 187Re/188Os from 0.0365 to 1.4469. The oldest age, calculated by TRD for the enclosed sulfides, is 2.1 Ga. An isochron age of 2.3±1.2 Ga is obtained by five grains of enclosed sulfides and primitive mantle. The sulfides used have lower Re-Os isotopic ratio than primitive mantle. Meanwhile, an isochron age of 645±225 Ma is given by all in- terstitial sulfides and the enclosed sulfides with higher Re-Os isotopic ratio due to Re addition after man- tle formation. In addition, the model age of 1.3 Ga recorded by one interstitial sulfide, having similar TDM and TRD, should be meaningful to deep thermal event. The coexistence of different ages, revealed by in situ Re-Os isotope, indicates frequently-occurring mantle events beneath Hannuoba area. | YU ChunMei ZHENG JianPing GRIFFIN W L | 2007 | Chinese Science Bulletin2007，52，20： | 10 |
| 14 | Forecast scheme and strategy for extended-range predictable components显示文摘Although extended-range forecasting has exceeded the limit of daily predictability of weather,there are still partially predictable characteristics of meteorological fields in such forecasts.A targeted forecast scheme and strategy for extended-range predictable components is proposed.Based on chaotic characteristics of the atmosphere,predictable components and unpredictable random components are separated by using the standpoint of error growth in a numerical model.The predictable components are defined as those with slow error growth at a given range,which are not sensitive to small errors in initial conditions. A numerical model for predictable components(NMPC)is established,by filtering random components with poor predictability.The aim is to maintain predictable components and avoid the influence of rapidly growing forecast errors on small scales. Meanwhile,the analogue-dynamical approach(ADA)is used to correct forecast errors of predictable components,to decrease model error and statistically take into account the influence of random components.The scheme is applied to operational dynamical extended-range forecast(DERF)model of the National Climate Center of China Meteorological Administration (NCC/CMA).Prediction results show that the scheme can improve forecast skill of predictable components to some extent, especially in high predictability regions.Forecast skill at zonal wave zero is improved more than for ultra-long waves and synoptic-scale waves.Results show good agreement with predictability of spatial scale.As a result,the scheme can reduce forecast errors and improve forecast skill,which favors operational use. | ZHENG ZhiHai HUANG JianPing FENG GuoLin CHOU JiFan | 2013 | Science China Earth Sciences2013，56，5： | 9 |
| 15 | Rescued virus from infectious cDNA clone of rabbit hemorrhagic disease virus is adapted to RK13 cells line显示文摘Based on the infectious full-length cDNA clone of rabbit hemorrhagic disease virus (RHDV), the in vitro transcripts are introduced into RK13 cells. 12 h later, CPE could be observed clearly, and virual antigen could also be detected by IFA. The titre of the recovered virus is 104.6/mL. Immune electron micro-scopic observation of the virus particles revealed that the particles were rotund with a diameter of about 30 nm. Besides, virus titre quantification obtained by qRT-PCR showed a correlation between time from infection and virus titre. All these results showed that we have recovered RHDV from RK13 cells by re-verse genetics technology successfully, and this would be very useful in studies of the antigenicity, virulence, pathogenesis, maturation and new type vaccines of RHDV. | LIU Guangqing NI Zheng YUN Tao ZHANG Yuying DU Qingyun SHENG Zutian LIANG Huali HUA Jionggang LI Shuangmao Chen Jianping | 2006 | Chinese Science Bulletin2006，51，14： | 9 |
| 16 | Subduction-zone peridotites and their records of crust-mantle interaction显示文摘Subduction is the core process of plate tectonics. The mantle wedge in subduction-zone systems represents a key tectonic unit, playing a significant role in material cycling and energy exchange between Earth's layers. This study summarizes research progresses in terms of subduction-related peridotite massifs, including supra-subduction zone(SSZ) ophiolites and mantle-wedge-type(MWT) orogenic peridotites. We also provide the relevant key scientific questions that need be solved in the future. The mantle sections of SSZ ophiolites and MWT orogenic peridotites represent the mantle fragments from oceanic and continental lithosphere in subduction zones, respectively. They are essential targets to study the crust-mantle interaction in subduction zones. The nature of this interaction is the complex chemical exchanges between the subducting slab and the mantle wedge under the major control of physical processes. The SSZ ophiolites can record melt/fluid-rock interaction, metamorphism,deformation, concentration of metallogenic elements and material exchange between crust and mantle, during the stages from the generation of oceanic lithosphere at spreading centers to the initiation, development, maturation and ending of oceanic subduction at continental margins. The MWT orogenic peridotites reveal the history of strong metamorphism and deformation during subduction, the multiple melt/fluid metasomatism(including silicatic melts, carbonatitic melts and silicate-bearing C-HO fluids/supercritical fluids), and the complex cycling of crust-mantle materials, during the subduction/collision and exhumation of continental plates. In order to further reveal the crust-mantle interaction using subduction-zone peridotites, it is necessary to utilize high-spatial-resolution and high-precision techniques to constrain the complex chemical metasomatism, metamorphism,deformation at micro scales, and to reveal their connections with spatial-temporal evolution in macro-scale tectonics. | Jianping ZHENG Qing XIONG Yi ZHAO Wenbo LI | 2019 | Science China Earth Sciences2019，62，7： | 8 |
| 17 | Garnet-bearing Granulite Facies Rock Xenoliths from Late Mesozoic Volcaniclastic Breccia, Xinyang, Henan Province显示文摘This paper presents the primary results of petrologic,mineralogical and petrochemical studies of garnet beating granulite facies rock xenoliths from Xinyang, Henan Province. These xenoliths, which are found in a pipe of late Mesozoic volcaniclastic breccia, are of high density (3.13-3.30 g/cm3) and high seismic velocity (Vp = 7.04-7.31 km/s), being products of underplating of basaltic magmas and had experienced granulite facies metamorphism. The underplating and metamorphism took place before the eruption of the host rock. Petrographical studies and equilibrium T-P calculations show that these xenoliths were captured at a 49 km depth and experienced at least a 16 km uplift before they were captured. The dynamics of the uplift could be related to the continent-continent collision between the North China plate and the Yangtze plate during the Triassic. | ZHENG Jianping, SUN Min, LU Fengxiang, WANG Chunyangand ZHONG Zengqiu Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074, China Department of Earth Sciences, The University of Hong Kong, China | 2001 | Acta Geologica Sinica(English Edition)2001，75，4： | 7 |
| 18 | Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease: a randomized controlled clinical study显示文摘OBJECTIVE: To assess the efficacy and safety of Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease(HFMD). METHODS: A stratified-block randomized, double-blind, parallel-controlled, and multicenter clinical trial was conducted with 360 patients in five hospitals across China: Quanzhou Children's Hospital, Shijiazhuang No. 5 Hospital, Shanghai Public Health Centre, Hunan Provincial Children's Hospital, and Kaifeng Children's Hospital. Patients were randomized into three groups with 120 in each. Group A was treated with Western Medicine, group B with Reduning injection, a Chinese herbal medicine, and group C with both Reduning injection and Western Medicine. Results were compared for treatment efficacy and safety on HFMD. The clinical outcomes were observed as follows: fever and onset time of antifebrile effect(time to bring the body temperature down ≥0.5℃ after medication); cumulative time for fever recovery(body temperature recovering to normal and lasting more than 24 h without medication); cumulative time for rash disappearance(without new rashes or ulcers appearing and the original ones fading away); and cumulative time for mouth ulcer disappearance. RESULTS: For the onset time of the antifebrile effect, there was no statistical difference between groups A and B(P>0.05) and groups B and C(P> 0.05). However, there was a statistical difference between groups A and C(P<0.05), and the effect in group C was the best. For the cumulative time for rash disappearance, there was no statistical difference between groups A and B(P>0.05). There were statistical differences between groups A and C, and groups B and C(P<0.05), and the effect in group C was the best. For the cumulative time for mouth ulcers disappearance, there were no statistical differences among the three groups(P>0.05). CONCLUSION: Reduning injection with Western Medicine for symptomatic treatment is most effective for mild HFMD. No adverse reactions were observed. | Guoliang Zhang Jie Zhao Liyun He Shiyan Yan Ziqiang Zhuo Haojie Zheng Yongping Mu Shuangjie Li Xi Zhang Jihan Huang Xiuhui Li Jianping Liu Hehe Wan Chaoyu Wei Wei Xiao | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 7 |
| 19 | Bph30confers resistance to brown planthopperby fortifying sclerenchyma in rice leaf sheaths显示文摘Phloem-feeding insects cause massive losses in agriculture and horticulture.Host plant resistance to phloem-feeding insects is often mediated by changes in phloem composition,which deter insect settling and feeding and decrease viability.Here,we report that rice plant resistance to the phloem-feeding brown planthopper(BPH)is associated with fortification of the sclerenchyma tissue,which is located just beneath the epidermis and a cell layer or two away from the vascular bundle in the rice leaf sheath.We found that BPHs prefer to feed on the smooth and soft region on the surface of rice leaf sheaths called the long-cell block.We identified Bph30 as a rice BPH resistance gene that prevents BPH stylets from reaching the phloem due to the fortified sclerenchyma.Bph30 is strongly expressed in sclerenchyma cells and enhances cellulose and hemicellulose synthesis,making the cell walls stiffer and sclerenchyma thicker.The structurally fortified sclerenchyma is a formidable barrier preventing BPH stylets from penetrating the leaf sheath tissues and arriving at the phloem to feed.Bph30 belongs to a novel gene family,encoding a protein with two leucine-rich domains.Another member of the family,Bph40,also conferred resistance to BPH.Collectively,the fortified sclerenchyma-mediated resistance mechanism revealed in this study expands our understanding of plant-insect interactions and opens a new path for controlling planthoppers in rice. | Shaojie Shi Huiying Wang Lingyun Nie Di Tan Cong Zhou Qian Zhang YiLi Bo Du Jianping Guo Jin Huang DiWu Xiaohong Zheng Wei Guan Junhan Shan Lili Zhu Rongzhi Chen Longjian Xue Linda L.Walling Guangcun He | 2021 | Molecular Plant2021，14，10： | 7 |
| 20 | Effects of Shuanghuanglian oral liquids on patients with COVID-19:a randomized,open-label,parallel-controlled,multicenter clinical trial显示文摘We conducted a randomized,open-label,parallel-controlled,multicenter trial on the use of Shuanghuanglian(SHL),a traditional Chinese patent medicine,in treating cases of COVID-19.A total of 176 patients received SHL by three doses(56 in low dose,61 in middle dose,and 59 in high dose)in addition to standard care.The control group was composed of 59 patients who received standard therapy alone.Treatment with SHL was not associated with a difference from standard care in the time to disease recovery.Patients with 14-day SHL treatment had significantly higher rate in negative conversion of SARS-CoV-2 in nucleic acid swab tests than the patients from the control group(93.4%vs.73.9%,P=0.006).Analysis of chest computed tomography images showed that treatment with high-dose SHL significantly promoted absorption of inflammatory focus of pneumonia,which was evaluated by density reduction of inflammatory focus from baseline,at day 7(mean difference(95%CI),−46.39(−86.83 to−5.94)HU;P=0.025)and day 14(mean difference(95%CI),−74.21(−133.35 to−15.08)HU;P=0.014).No serious adverse events occurred in the SHL groups.This study illustrated that SHL in combination with standard care was safe and partially effective for the treatment of COVID-19. | Li Ni Zheng Wen Xiaowen Hu Wei Tang Haisheng Wang Ling Zhou Lujin Wu Hong Wang Chang Xu Xizhen Xu Zhichao Xiao Zongzhe Li Chene Li Yujian Liu Jialin Duan Chen Chen Dan Li Runhua Zhang Jinliang Li Yongxiang Yi Wei Huang Yanyan Chen Jianping Zhao Jianping Zuo Jianping Weng Hualiang Jiang Dao Wen Wang | 2021 | Frontiers of Medicine2021，15，5： | 7 |
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