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| 1 | Sensitivity analysis of dimensionless parameters for physical simulation of water-flooding reservoir显示文摘A numerical approach to optimize dimensionless parameters of water-flooding porous media flows is proposed based on the analysis of the sensitivity factor defined as the variation ration of a target function with respect to the variation of dimensionless parameters. A complete set of scaling criteria for water-flooding reservoir of five-spot well pattern case is derived from the 3-D governing equations, involving the gravitational force, the capillary force and the compressibility of water, oil and rock. By using this approach, we have estimated the influences of each dimensionless parameter on experimental results, and thus sorting out the dominant ones with larger sensitivity factors ranging from 10?4 to 100. | BAI Yuhu LI Jiachun ZHOU Jifu | 2005 | Science China(Technological Sciences)2005，48，4： | 7 |
| 2 | A new free-hand pedicle screw placement technique with reference to the supraspinal ligament显示文摘We sought to compare the safety and accuracy of a new free-hand pedicle screw placement technique to that of the conventional technique.One hundred fifty-three consecutive adult patients with simple fracture in the thoracic or/and lumbar spine were alternately assigned to either the new free-hand or the conventional group.In the new free-hand technique group,preoperative computerized tomography(CT) images were used to calculate the targeted medial-lateral angle of each pedicle trajectory and the pedicle screw was inserted perpendicular to the corresponding supraspinal ligament.In the conventional technique group,the medial-lateral and cranial-caudal angle of each pedicle trajectory was determined by intraoperatively under fluoroscopic guidance.The accuracy rate of pedicle screw placement,the time of intraoperative fluoroscopy,the operating time and the amount of blood loss during operation were respectively compared.All screws were analyzed by using intraoperative radiographs,intraoperative triggered electromyography(EMG) monitoring data,postoperative CT data and clinical outcomes.The accuracy rate of pedicle screw placement in the new free-hand technique group and the conventional technique group was 96.3% and 94.2%(P < 0.05),respectively.The intraoperative fluoroscopy time of the new technique group was less than that of the conventional technique group(5.37 seconds vs.8.79 seconds,P < 0.05).However,there was no statistical difference in the operating time and the amount of blood loss during operation(P > 0.05).Pedicle screw placement with the free-hand technique which keeps the screw perpendicular to the supraspinal ligament is an accurate,reliable and safe technique to treat simple fracture in the thoracic or lumbar spine. | Juming Li Hong Zhao Hao Xie Lipeng Yu Jifu Wei Min Zong Feng Chen Ziqiang Zhu Ning Zhang Xiaojian Cao | 2014 | The Journal of Biomedical Research2014，28，1： | 7 |
| 3 | An optimization approach to the similarity criteria of flows and its application显示文摘在现在的纸,我们建议一条优化途径调查复杂流动的 similiarity 标准。与这条途径,我们可以识别由数字敏感分析管理复杂流动的主导的尺寸更少变量。第一,我们定义敏感因素并且少些在尺寸上检验它的依赖变量。然后,我们使用这条途径在一座假定的油水库学习多孔的媒介流动的类似标准。从数字敏感分析获得的类似原则与理论法律一致,因此表明建议优化途径的可行性。进一步的解释被从它的原型在一个模型分析压力分发的偏差给。另外,我们在敏感因素上检验流动参数变化的效果并且发现主导的尺寸更少变量可以从参数的不同集合变化。 | ZHOU Jifu LI Jiachun | 2006 | Progress in Natural Science:Materials International2006，16，3： | 5 |
| 4 | Fluid Inclusion Geochemistry of Metallic Ore Deposits in the South- Central Sector of theDa Hinggan Mountains in China显示文摘Physicochemical parameters of mineralization such as temperature, pressure, salinity, density, composition and boiling of ore fluids as well as pH, Eh, fo2 and reducing parameter in theprocess of mineralization of major ore deposits in the study district have been obtained by the authors through systematic observation and determination of characteristics and phase changes of fluid inclusions at different temperatures and analysis of gaseous and liquid phase compositions of the inclusions, thus providing a scientific basis for the division of mineralization-alteration stages, types of mineral deposits and minerogenetic series and the deepening of the knowledge about the ore-forming processes and mechanisms of mineral deposits. It is indicated that the deposits of the same type have similar fluid inclusion geochemical features and physicochemical parameters though they belong to different minerogenetic series, while the compositions of inclusions are not conditioned by deposit types but closely related | Sheng Jifu, Zhang Dequan and Li YanInstitute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijing Jiang M inxi | 1995 | Acta Geologica Sinica(English Edition)1995，69，3： | 3 |
| 5 | Preparation and Optimization of Resveratrol Nanosuspensions by Antisolvent Precipitation Using Box-Behnken Design显示文摘 | Jifu Hao Yun Gao Jing Zhao Jimei Zhang Qiankui Li Zhongxi Zhao Jiyong Liu | 2015 | AAPS PharmSciTech2015，，： | 2 |
| 6 | Effects of flavonoids derived from Taxus yunnanensis on p-glycoprotein and cytochrome P450 3A4显示文摘The intestinal uptake of paclitaxel is hampered by trans-membrane efflux transporters such as P-glycoprotein(P-gp),and paclitaxel is mainly metabolized by cytochrome P4503A4(CYP3A4)presented in the liver.Our previous results demonstrated that flavonoids extracted from Taxus yunnanensis could improve the oral absorption of paclitaxel.The current study was purposed to investigate the effects of the flavonoid extracts on P-gp and CYP3A4 in vitro.The expression and activity of P-gp were detected by western blotting and intracellular rhodamine 123 accumulation assay in Caco-2 cells treated with the flavonoids extract.The expression of CYP3A4 was investigated by western blotting in mouse primary hepatocytes and the activity of CYP3A4 was detected by LC-MS/MS method using rat liver microsomes.Our results showed that the flavonoid extracts from T.yunnanensis could inhibit P-gp activity and concurrently decrease the expression and activity of CYP3A4.In conclusion,activity of P-gp and CYP3A4 could be inhibited by flavonoids extracted from T.yunnanensis which might be potential candidates for development of oral formulation of paclitaxel. | Jifu Li Dake Cai Huichang Bi Jing Jin Min Huang | 2013 | Asian Journal of Pharmaceutical Sciences2013，8，3： | 2 |
| 7 | The prevalence of hyperuricemia and its correlates in an inland Chinese adult population, urban and rural of Jinan显示文摘 | Jianmin Yang Zhendong Liu Cheng Zhang Yingxin Zhao Shangwen Sun Shujian Wang Yuxia Zhao Yun Zhang Jifu Li Fanghong Lu | 2013 | Rheumatology International2013，，6： | 2 |
| 8 | Ultrastretchable and wearable conductive multifilament enabled by buckled polypyrrole structure in parallel显示文摘Stretchable conductive fibers have attracted much attention due to their potential use in wearable electronics.However,the ultrahigh strain insensitive conductivity is hindered by mechanical mismatch in Young’s modulus and failure of stretchable structures under large deformation.This challenge is addressed with a conductive and elastic multifilament made of the polyurethane monofilaments that are surface-coated with buckled polypyrrole(PPy)of which flexibility is improved by sodium sulfosalicylate.Such parallel conductive monofilaments with PPy buckling on surface reduce the influence of cracks in the conductive coating on the overall conductivity,displaying an ultra-high strain insensitive behavior(quality factor Q=10.9).Remarkably,various complex forms of wearable electronic textiles made by this conductive multifilament maintain the strain-insensitive behavior of the original multifilament,even upon the large deformation of human joint.This multifilament with wrinkled PPy has attractive advantages in the application of super-stretched wearable electronic devices. | Yimeng Li Yaya Gao Lizhen Lan Qian Zhang Leqian Wei Mengqi Shan Lamei Guo Fujun Wang Jifu Mao Ze Zhang Lu Wang | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 9 | Plasma biomarkers and plaque strain predict long-term cardiovascular events in patients with acute coronary syndrome显示文摘To test whether circulating and intracoronary biomarkers and coronary plaque strain have additive values to Global Registry of Acute Coronary Events(GRACE) score for predicting long-term cardiovascular events in ACS patients. One hundred ACS patients were enrolled and the GRACE score and plasma levels and intracoronary gradients of a number of biomarkers were measured. Coronary plaque burden and morphology in non-critical stenotic plaques were determined by intravascular ultrasound(IVUS) technique, and the maximal shear strain(SSmax) and maximal area strain(ASmax) were determined by intravascular ultrasound elastography(IVUSE) technique. Patients were followed for cardiovascular events and the predictive values of clinical characteristics, plasma biomarkers and plaque parameters were compared with GRACE score, and the incremental values of these measurements to the GRACE score were assessed. GRACE score, plasma biomarkers and plaque strain were independent predictors of cardiovascular events. Combination of GRACE score, plasma biomarkers and plaque strains significantly improved the predictive value of the GRACE score alone with the receiver-operating characteristic area increased from0.457 to 0.667(P=0.014). The combination of circulating and intracoronary biomarkers, plaque strain and GRACE score provides a better predictive tool than GRACE score alone in patients with ACS. | Mingjun Xu Xiaobo Hu Lin Wang Wei Zhang Lindi Wu Jifu Li Yuguo Chen Pengfei Zhang Haijun Su Yaling Han Cheng Zhang Mei Zhang Yun Zhang | 2020 | Science China(Life Sciences)2020，63，2： | 1 |
| 10 | Multi-scale calculation of settling speed of coarse particles by accelerated Stokesian dynamics without adjustable parameter显示文摘The calculation of settling speed of coarse particlesis firstly addressed, with accelerated Stokesian dynamicswithout adjustable parameters, in which far field force actingon the particle instead of particle velocity is chosen asdependent variables to consider inter-particle hydrodynamicinteractions. The sedimentation of a simple cubic array ofspherical particles is simulated and compared to the resultsavailable to verify and validate the numerical code andcomputational scheme. The improved method keeps the samecomputational cost of the order O (N log N) as usualaccelerated Stokesian dynamics does. Then, more realisticrandom suspension sedimentation is investigated with thehelp of Mont Carlo method. The computational results agreewell with experimental fitting. Finally, the sedimentation offiner cohesive particle, which is often observed in estuaryenvironment, is presented as a further application in coastalengineering. | Long Wang Jiachun Li Jifu Zhou Institute of Mechanics, CAS, 100190 Beijing, China | 2009 | Acta Mechanica Sinica2009，25，3： | 1 |
| 11 | Conductive fibers for biomedical applications显示文摘Bioelectricity has been stated as a key factor in regulating cell activity and tissue function in electroactive tissues.Thus,various biomedical electronic constructs have been developed to interfere with cell behaviors to promote tissue regeneration,or to interface with cells or tissue/organ surfaces to acquire physiological status via electrical signals.Benefiting from the outstanding advantages of flexibility,structural diversity,customizable mechanical properties,and tunable distribution of conductive components,conductive fibers are able to avoid the damage-inducing mechanical mismatch between the construct and the biological environment,in return to ensure stable functioning of such constructs during physiological deformation.Herein,this review starts by presenting current fabrication technologies of conductive fibers including wet spinning,microfluidic spinning,electrospinning and 3D printing as well as surface modification on fibers and fiber assemblies.To provide an update on the biomedical applications of conductive fibers and fiber assemblies,we further elaborate conductive fibrous constructs utilized in tissue engineering and regeneration,implantable healthcare bioelectronics,and wearable healthcare bioelectronics.To conclude,current challenges and future perspectives of biomedical electronic constructs built by conductive fibers are discussed. | Leqian Wei Shasha Wang Mengqi Shan Yimeng Li Yongliang Wang Fujun Wang Lu Wang Jifu Mao | 2023 | Bioactive Materials2023，，4： | 1 |
| 12 | Burst detection in turbulent channel flows based on large eddy simulation databases显示文摘Reliable turbulent channel flow databases at several Reynolds numbers have been established by large eddy simulation (LES), with two of them validated by comparing with typical direct numerical simulation (DNS) results. Furthermore, the statistics, such as velocity profile, turbulent intensities and shear stress, were obtained as well as the temporal and spatial structure of turbulent bursts. Based on the LES databases available, the conditional sampling methods are used to detect the structures of burst events. A method to deterimine the grouping parameter from the probability distribution function (pdf) curve of the time separation between ejection events is proposed to avoid the errors in detected results. And thus, the dependence of average burst period on thresholds is considerably weakened. Meanwhile, the average burst-to- bed area ratios are detected. It is found that the Reynolds number exhibits little effect on the burst period and burst-to-bed area ratio. | ZHANG Qiang ZHOU Jifu LI Jiachun | 2005 | Science China(Physics,Mechanics & Astronomy)2005，48，4： | 1 |
| 13 | Assessment of Building Physical Vulnerability in Earthquake‑Debris Flow Disaster Chain显示文摘Large earthquakes not only directly damage buildings but also trigger debris fows,which cause secondary damage to buildings,forming a more destructive earthquake-debris fow disaster chain.A quantitative assessment of building vulnerability is essential for damage assessment after a disaster and for pre-disaster prevention.Using mechanical analysis based on pushover,a physical vulnerability assessment model of buildings in the earthquake-debris fow disaster chain is proposed to assess the vulnerability of buildings in Beichuan County,China.Based on the specifc sequence of events in the earthquake-debris fow disaster chain,the seismic vulnerability of buildings is 79%,the fow impact and burial vulnerabilities of damaged buildings to debris fow are 92%and 28%respectively,and the holistic vulnerability of buildings under the disaster chain is 57%.By comparing diferent vulnerability assessment methods,we observed that the physical vulnerability of buildings under the disaster chain process is not equal to the statistical summation of the vulnerabilities to independent hazards,which implies that the structural properties and vulnerability of buildings have changed during the disaster chain process.Our results provide an integrated explanation of building vulnerability,which is essential for understanding building vulnerability in earthquake-debris fow disaster chain and building vulnerability under other disaster chains. | Hao Zheng Zhifei Deng Lanlan Guo Jifu Liu Lianyou Liu Tiewei Li Huan Zheng Tao Zheng | 2023 | International Journal of Disaster Risk Science2023，14，4： | 0 |
| 14 | Effects of Mechanical Harvesting of Main Crop on Soil Rolling and Yield of Ratooned Rice显示文摘[Objectives]To study the effect of mechanical harvesting of main crop on soil rolling and yield of ratooned rice.[Methods]In this study,the harvesting method was optimized and improved through field research and theoretical research.[Results]Compared with farmers'habits,the mechanical harvesting method could significantly increase the working area per unit time and reduce the rolling area in the field,but it would increase the rolling rate of the land or transfer area.At the same time,the optimization method could reduce the soil bulk density in the primary rolling area,but it had no significant impact on soil compactness.[Conclusions]Compared with the farmer's customary method,the optimization method could reduce the crushing and damage of rice piles in the field,increase the seedling rate and panicle extraction rate,thus increasing the yield of rice in the ratooning season. | Ruyu YAN Ximei ZHAO Jifu LI | 2022 | Asian Agricultural Research2022，14，10： | 0 |
| 15 | Analytical solutions of turbulent boundary layer beneath forward-leaning waves显示文摘As a typical nonlinear wave,forward-leaning waves can be frequently encountered in the near-shore areas,which can impact coastal sediment transport significantly.Hence,it is of significance to describe the characteristics of the boundary layer beneath forward-leaning waves accurately,especially for the turbulent boundary layer.In this work,the linearized turbulent boundary layer model with a linear turbulent viscosity coefficient is applied,and the novel expression of the near-bed orbital velocity that has been worked out by the authors for forward-leaning waves of arbitrary forward-leaning degrees is further used to specify the free stream boundary condition of the bottom boundary layer.Then,a variable transformation is found so as to make the equation of the turbulent boundary layer model be solved analytically through a modified Bessel function.Consequently,an explicit analytical solution of the turbulent boundary layer beneath forward-leaning waves is derived by means of variable separation and variable transformation.The analytical solutions of the velocity profile and bottom shear stress of the turbulent boundary layer beneath forward-leaning waves are verified by comparing the present analytical results with typical experimental data available in the previous literature. | Yiqin XIE Jifu ZHOU Xu WANG Jinlong DUAN Yongjun LU Shouqian LI | 2024 | Applied Mathematics and Mechanics(English Edition)2024，45，4： | 0 |
| 16 | Design and Implement of International Students' Management and Security Warning System Based on B/S Architecture显示文摘 | Yulu Zhang Zhikun Li Ya Wen Jifu Wang Ruigai Li | 2018 | 国际计算机前沿大会会议论文集2018，，2： | 0 |
| 17 | Polymeric Hydrogel Nanocapsules: A Thermo and pH Dual-responsive Carrier for Sustained Drug Release显示文摘Hydrogel capsules show attractive prospects in drug delivery recently because of high drug loading and sustained release behavior. In this study we reported a simple and convenient route to fabricate poly(acrylic acid)-poly(N-isopropylacrylamide)(PAA-PNIPAm) hydrogel capsules by using hydroxypropylcellulose-poly(acrylic acid)(HPC-PAA) complexes as the templates. The capsules showed a high drug loading(~280% to the weight of capsules) for Doxorubicin hydrochloride. The release of drug from the capsules was responsive to the temperature and p H of the surroundings, showing a low-rate but sustained release behavior favorable for low-toxic and long-term therapy. Together with the convenient preparation, high drug loading, dual responsivity as well as the sustained release feature, it is implied that this polymeric hydrogel capsule might be a promising candidate for new drug carriers. | Jingya Nan Ying Chen Rutian Li Jifu Wang Meihong Liu Chunpeng Wang Fuxiang Chu | 2014 | Nano-Micro Letters2014，6，3： | 0 |
| 18 | Ultrasensitive detection of IgE levels based on magnetic nanocapturer linked immunosensor assay for early diagnosis of cancer显示文摘Rapid and accurate detection of immunoglobulin E(Ig E) in serum and reduction of serum dosage are of great significance for clinical detection. Herein, we described a rapid magnetic separation of Ig E from patient serum based on Fe3 O4@Si O2-NTA@026 sdab as the capture probe and multiple horseradish peroxidase(HRP)-labeled antibodies linked gold nanoparticles(Au NPs) as chemiluminescence(CL) signal amplifier for ultrasensitive detection of total Ig E. Results showed that the limit of detection of our immunosensor system in serum samples was 0.03 k U/L, which is lowest in comparison with current methods, and far lower than that of Immuno CAP for Ig E detection(0.1 k U/L). Furthermore, our immunosensor possessed satisfied repeatability and accuracy, as well as good stability. In comparison with the Immuno CAP for the quantitative detection of Ig E, highly consistent results were achieved in 20 serum samples. Specially, this method was also successfully utilized for assessing the Ig E traces in breast cancer patients,which provides a new idea for the diagnosis of early cancer. Therefore, we believe that such versatile immunosensor will offer an alternative method for the on-site monitoring and determination of various Ig E-related diseases. | Yongxin Liu Mengda Cao Zhongxi Huang Changmin Yu Naidi Yang Qiong Wu Liang Shi Wenjie Duan Yi Zhu Jifu Wei Lin Li Wei Huang | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 19 | Raloxifene hydrochloride treatment leads to better outcomes than medroxyprogesterone acetate when paired with estrogen in ovariectomized cholesterol-fed rabbits显示文摘 | Caiyu Zeng Falin Yang Hong He Keqing Hu Xin Wang Qin Hu Jifu Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 0 |
| 20 | Highly stable side-chain-type cardo poly(aryl ether ketone)s membranes for vanadium flow battery显示文摘Vanadium flow batteries(VFBs)have drawn considerable attention as an emerging technology for largescale energy storage systems(ESSs).One of the pivotal challenges is the availability of eligible ion exchange membranes(ICMs)that provide high ion selectivity,proton conductivity,and stability under rigorous condition.Herein,a‘side-chain-type’strategy has been employed to fabricate highly stable phenolphthalein-based cardo poly(arylene ether ketone)s(PAEKs)membrane with low area resistance(0.058Ωcm^(2)),in which flexible alkyl spacers effectively alleviated inductive withdrawing effect from terminal ion exchange groups thus enabling a stable backbone.The assembled VFBs based on PAEKs bearing pendent alkyl chain terminated with quaternary ammonium(Q-PPhEK)demonstrated an energy efficiency above 80%over 700 cycles at 160 mA/cm^(2).Such a remarkable results revealed that the side-chain-type strategy contributed to enhancing the ICMs stability in strong oxidizing environment,meanwhile,more interesting backbones would be woken with this design engaging in stable ICMs for VFBs. | Ziming Zhao Qing Dai Sihan Huang Wenjing Lu Yaohan Chen Jifu Zheng Suobo Zhang Shenghai Li Xianfeng Li | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
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