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| 1 | Expression of neurocan mRNA and ultrastructure of brain tissue after cerebral ischemia and reperfusion in stroke-prone renovascular hypertensive rats treated by electroacupuncture显示文摘We established a stroke-prone renovascular hypertensive rat model by bilateral constriction of the renal artery with sliver loop clips. After ten weeks, middle cerebral artery occlusion was induced for 2 hours. The rats then received electro-acupuncture at Baihui (DU 20) and Dazhui (DU 14) after onset of ischemia for 30 days. In situ hybridization study showed that electroacupuncture significantly reduced the number of neurocan mRNA-positive cells in the ischemic penumbra and hippocampal tissues of rats. Electron microscopy results demonstrated that the structure of neurons and blood vessels in the ischemic tissues were restored with electroacupuncture. Overall, these data suggest that electroacupuncture may protect neurons against ischemic reperfusion injury in stroke-prone renovascular hypertensive rats, which may be regulated by downregulation of expression of nerve inhibitory factor neurocan mRNA. | Feng Tan Saiying Wan Haike Wu Qiwen HUO Jinliang Wang Wenlin Chen Meifeng Fang Xiaolin Liu Xuewen Wang Jingbo Sun | 2011 | Neural Regeneration Research2011，6，36： | 8 |
| 2 | Initial scalar lithospheric magnetic anomaly map of China and surrounding regions derived from CSES satellite data显示文摘The China Seismo-Electromagnetic Satellite(CSES),China’s first satellite to measure geophysical fields with scientific goals in both space and solid earth physics,was launched successfully in February 2018.It carries high-precision magnetometers to measure the geomagnetic field.In this study,the CSES magnetic data were used to extract the signal of the lithospheric magnetic field caused by magnetized rocks in the crust and uppermost mantle.First,an along-track analysis of the CSES magnetic data was undertaken near the Bangui magnetic anomaly in central Africa and the Tarim magnetic anomaly in China,demonstrating that the CSES magnetic data are indeed sensitive to the lithospheric magnetic anomaly field.Then a lithospheric magnetic anomaly map over China and surrounding regions was derived.This map is consistent with the lithospheric part of the CHAOS-7 model.In particular,it clearly reveals four major magnetic anomalies containing long-wavelength signals at the altitude of lowearth-orbiting satellites.Three magnetic highs are located over the Tarim,Sichuan and Songliao basin,the origins of which could be related to large-scale tectonic-magmatic activities during geological history.A prominent magnetic low is otherwise found in the southern Himalayan-Tibetan plateau,possibly caused by the shallow Curie depth in this region.To further improve the precision of the lithospheric magnetic field model,more detailed data processing and multi-source data merging are needed. | WANG Jie SHEN XuHui YANG YanYan ZEREN ZhiMa HULOT Gauthier OLSEN Nils ZHOU Bin MAGNES Werner DE SANTIS Angelo HUANG JianPing GUO Feng LIU WenLong YU JingBo | 2021 | Science China(Technological Sciences)2021，64，5： | 4 |
| 3 | Structural requirements and interaction mechanisms of ACE inhibitory peptides:molecular simulation and thermodynamics studies on LAPYK and its modifi ed peptides显示文摘The understanding of the structural requirements and the intermolecular-interaction mechanism are important for discovering potent angiotensin-converting enzyme(ACE)inhibitory peptides.In this study,we modifi ed an egg-white derived peptide,LAPYK,using the amino acids with different properties to produce the LAPYK-modified peptides.The ACE inhibitory activities of the modified peptides were determined to explore the structural requirements of ACE inhibitory peptides(ACEIPs).Molecular simulation and isothermal titration calorimetry analysis were used to investigate interactions between the peptides and ACE.We found that hydrophobicity and the amino acids with ring structures were benefi cial for the ACE inhibitory activities of the peptides.The results of the molecular mechanics poisson boltzmann surface area(MMPBSA)binding free energy calculations indicated that the polar solvation free energy(ΔG_(polar))of the charged peptides(LAPYK,LAPYE)were unfavorable for binding to ACE.On the other hand,the results of isothermal titration calorimetry analyses suggested that the enthalpy-driven ACE-peptide interactions were more favorable than the entropy-driven ACE-peptide interaction counterparts. | Biying Zhang Jingbo Liu Hedi Wen Feng Jiang Erlei Wang Ting Zhang | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 4 | Effect of loss and coupling on the resonance of metamaterial:An equivalent circuit approach显示文摘In this work we establish an equivalent circuit model to analyze the resonace of the metamaterial considering the loss of the unit cell and coupling effect between them.From this model,we find that metamaterial can be divided into three categories:weak,critical and strong couplings,depending on the values of the loss and coupling strength,where the different resonant properties are presented.The physical reason of the division is whether the loss in each unit cell can be offset by energy coupling from the adjunct unit cells.Full-wave electromagnetic simulations have also been carried out to verify the equivalent circuit analysis.Our circuit analysis provides a simple and effective way to understand the coupling of the metamaterial and gives guidance for the analysis and design of the metamaterial. | ZHANG YongGang WU JingBo LIANG LanJu ZHOU GaoChao JIN BiaoBing FENG YiJun | 2014 | Science China(Information Sciences)2014，57，12： | 3 |
| 5 | 0il bleed from elastomeric thermal silicone conductive pads显示文摘 | Yuqi Chen Yakai Feng Jingqi Zhao Jingbo Shen Menghuang Feng | 2016 | Frontiers of Chemical Science and Engineering2016，10，4： | 3 |
| 6 | Effect of Trace Sn on Pitting Behaviors of High Voltage Anode Aluminum Foil显示文摘The effect of trace Sn on the pitting morphology of high voltage anode aluminum foils was investigated.The distributions of microelement Sn,Fe,Si,Cu and Mg in the surface layer of aluminum foils with different Sn content were determined by using a secondary ion mass spectrometer.It was found that the micro-alloyed Sn is enriched at the external surface.The mechanism of pitting behavior of trace Sn on aluminum surface is similar with that of lead.Enrichment of Sn in the surface layer provides large numbers of sites for initiation of pitting corrosion,while pitting sites appeared relatively inhomogenously in the foils without Sn.Sn,as an eco-friendly microelement,can be applied to replace Pb in improving the homogenous pitting behaviors of high voltage aluminum foils,in which the volume fraction of cube texture is not reduced. | Jingbo SONG Weimin MAO Hong YANG Huiping FENG | 2008 | Journal of Materials Science & Technology2008，24，5： | 2 |
| 7 | A real-size MRPC developed for CBM-TOF显示文摘An MRPC prototype for the future CBM-TOF inner area has been developed.The counter assembled with low resistive glass consists of 10×0.22 mm gas gaps and 2×8 readout pads.The size of each pad is 20 mm×20 mm with an interval of 2 mm between pads.The signals of the counter are collected by 4 eight-pin connectors.Preliminary tests performed with cosmic-rays showed an efficiency over 98%and a time resolution around 60 ps.The measured crosstalk,dark current and dark rate were at a very low levels.Results under uniform irradiation performed at JINR with high energy deuteron showed a time resolution of40–50 ps and over 98%efficiency at a low flux rate,meanwhile at a flux up to 70 kHz/cm2,93%efficiency and 77 ps time resolution still remained.These excellent performances call fully meet the demand of CBM-TOF inner wall. | ZHU WeiPing WANG Yi FENG ShengQin WANG JingBo HUANG XinJie SHI Li BABKIN V. GOLOVATYUK V. RUMIANTCEV M. | 2013 | Science China(Technological Sciences)2013，56，11： | 1 |
| 8 | Comparison of anti-diabetic effects of polysaccharides from corn silk on normal and hyperglycemia rats显示文摘 | Wenzhu Zhao Yongguang Yin Zhipeng Yu Jingbo Liu Feng Chen | 2012 | International Journal of Biological Macromolecules2012，，4： | 1 |
| 9 | Directional terahertz holography with thermally active Janus metasurface显示文摘Dynamic manipulation of electromagnetic(EM)waves with multiple degrees of freedom plays an essential role in enhancing information processing.Currently,an enormous challenge is to realize directional terahertz(THz)holography.Recently,it was demonstrated that Janus metasurfaces could produce distinct responses to EM waves from two opposite incident directions,making multiplexed dynamic manipulation of THz waves possible.Herein,we show that thermally activated THz Janus metasurfaces integrating with phase change materials on the meta-atoms can produce asymmetric transmission with the designed phase delays.Such reconfigurable Janus metasurfaces can achieve asymmetric focusing of THz wave and directional THz holography with free-space image projections,and particularly the information can be manipulated via temperature and incident THz wave direction.This work not only offers a common strategy for realizing the reconfigurability of Janus metasurfaces,but also shows possible applications in THz optical information encryption,data storage,and smart windows. | Benwen Chen Shengxin Yang Jian Chen Jingbo Wu Ke Chen Weili Li Yihui Tan Zhaosong Wang Hongsong Qiu Kebin Fan Caihong Zhang Huabing Wang Yijun Feng Yunbin He Biaobing Jin Xinglong Wu Jian Chen Peiheng Wu | 2023 | Light(Science & Applications)2023，12，6： | 1 |
| 10 | Layer-by-layer slot-die coated high-efficiency organic solar cells processed using twin boiling point solvents under ambient condition显示文摘Layer-by-layer (LbL) strategy has been developed to form bulk heterojunction (BHJ) structure for processing efficient organic solar cells (OSCs). Herein, LbL slot-die coating with twin boiling point solvents (TBPS) strategy was developed to fabricate highly efficient OSCs, which matches with large-scale, high throughput roll-to-roll (R2R) industrialized mass process. The TBPS strategy could produce high-quality thin film without any additive, leading to the optimized vertical phase separation with interpenetrating nanostructures, as well as the enhanced charge transport and extraction. Thus, the power conversion efficiency up to 14.42% was achieved for [(2,6-(4,8-bis(5-(2-ethylhexyl-3-fluoro)thiophen-2-yl)-benzo [1,2-b:4,5-b′]dithiophene))-alt-(5,5-(1′,3′-di-2-thienyl-5′,7′-bis(2-ethylhexyl)benzo[1′,2′-c:4′,5′-c′]dithiophene-4,8-dione)]:2,2′-((2Z,2′Z)-((12,13-bis(2-ethylhexyl)-3,9-diundecyl-12,13-dihydro-[1,2,5]thiadiazolo[3,4-e]thieno[2″,3″:4″,5″]thieno[2′,3′:4,5]pyrrolo[3,2-g]thieno[2′,3′:4,5]thieno[3,2-b]indole-2,10-diyl)bis(methanylylidene)) bis(5,6-difluoro-3-oxo-2,3-dihydro-1H-indene-2,1-diylidene))dimalononitrile (PM6:Y6) OSCs fabricated via sequentially LbL slot-die coating using the TBPS strategy under ambient condition. The research provides a potential route for industrialized production of high-efficiency and large-area OSC devices. | Yu Yang Erming Feng Hengyue Li Zichao Shen Wanrong Liu Jingbo Guo Qun Luo Jidong Zhang Guanghao Lu Changqi Ma Junliang Yang | 2021 | Nano Research2021，14，11： | 1 |
| 11 | Effect of yttrium on the corrosion behaviour of 09CrCuSb alloy in concentrated sulphuric acid显示文摘 | Xinxin Wang Yimin Gao Kuang Li Jingbo Yan Yefei Li Jianbo Feng | 2013 | Corrosion Science2013，，： | 1 |
| 12 | Effect of cyclovirobuxine D on human growth-associated protein 43 and neurocan expression in ischemic brain tissue of stroke-prone renovascular hypertensive rats显示文摘BACKGROUND: Experimental data indicate that human growth-associated protein 43 mRNA expression coincides with axonal growth during nerve ganglion development; while neurocan, secreted from astrocytes, can inhibit sprouting and elongation of the axonal growth cone. OBJECTIVE: To verify regulatory effects of cyclovirobuxine D (CVB-D) extracted from Chinese box branchlet on human growth-associated protein 43 (GAP-43), and neurocan expression in brain tissue of stroke-prone renovascular hypertensive (RHRSP) rats, at different time points after cerebral ische-mia/reperfusion. DESIGN: Randomized grouping design and controlled animal study. SETTING: This study was performed at the Center of Guangdong Hospital of Traditional Chinese Medicine (a national key laboratory) from March 2003 to September 2006. MATERIALS: 100 healthy male Sprague-Dawley rats, aged 2-3 months and weighing 90-120 g, were se- lected for this study. CVB-D was provided by Nanjing Xiaoying Pharmaceutical Factory (Batch number: 307701). METHODS: The initial tip of renal arteries was clamped bilaterally for 10 weeks to establish the RHRSP model. 100 RHRSP rats were randomly divided into 4 groups: naive group (n = 10), sham surgery group (n = 10), CVB-D group (n = 40), and lesion group (n = 40). Rats in the naive group did not undergo any treatment, and cervical vessels of rats in the sham surgery group were exposed, but not blocked. The right middle cerebral artery of rats in the CVB-D group and lesion group were occluded to establish cerebral ischemia. Rats in the CVB-D group were intraperitoneally injected with CVB-D (6.48 mg/kg) every day and with saline (1.5 mL/injection) twice a day. Rats in the lesion group were intraperitoneally injected with saline (2 mL/injection). MAIN OUTCOME MEASURES: Immunohistochemistry was applied to detect GAP-43 and neurocan expression in the ischemic penumbra region of CVB-D and lesion brains at 2 hours post-cerebral ischemia and at 1, 7, 14, and 30 days post-perfusion (n = 10 at each time point). Similarly, GAP-43 and neurocan expres- sion was detected in the right hemisphere of na?ve and sham-operated animals. The results were expressed as positive cells. RESULTS: A total of 100 rats were included in the final analysis. The number of GAP-43 positive cells in- creased in the CVB-D group 1, 7, 14, and 30 days post-cerebral ischemia/perfusion compared to the lesion group, as indicated by a significant difference between the CVB-D and lesion group (P < 0.05-0.01). The number of neurocan-positive cells decreased in the CVB-D group on the first day compared to the model group; however, there was no significant difference between the two groups (P > 0.05). On post-ischemia days 7, 14, and 30, the number of neurocan-positive cells in the CVB-D group was significantly less than in the lesion group (P < 0.05). Both, GAP-43 and neurocan expression was not detectable in brains of na?ve and sham-operated animals. CONCLUSION: CVB-D treatment up-regulated GAP-43 expression and down-regulated neurocan expression in the ischemic region of RHRSP rats. | Feng Tan Wei Gu Saiying Wan Haike Wu Jinliang Wang Jingbo Sun Jiamao Cheng Xin Zhang Renfeng Huang | 2008 | Neural Regeneration Research2008，3，4： | 1 |
| 13 | Anti-inflammation Activities of Essential Oil and Anti-microbial Activities Of Ethanol Extraction from China's Rosemary显示文摘Rosemary(Rosmarius officinalis L.), an endemic plant species in south region of China, is traditionally used as a spice. In this research, the anti-inflammatory activities of essential oil and the antibacterial activities of ethanol extraction were determined, respectively. Results showed that based on the GC-MS analysis there were 35 kinds of active ingredients in the essential oil in totally, mainly including D-limonene(24.158 ml/L), α-Pinene(23.325 ml/L), Camphor(9.855 ml/L),Camphene(7.076 ml/L), Verbenone(6.685 ml/L), Borneol(5.580 ml/L), etc. The LCUV determination indicated that the main components in the ethanol extractionwere rosmarinic acid(3 910 mg/kg) and carnosic acid(2 970 mg/kg). By mice peritoneal macrophage phagocytosis of chicken erythrocytes experiment, the essential oil of rosemary was shown having a significant role in anti-inflammation. And the ethanol extraction had broad-spectrum antibacterial effects, but had no effect on mold by the agar diffusion method of 8 bacteria. As a result, both rosemary essential oil and ethanol extraction had good potential medicinal values. | Jingbo ZHOU Ruqiang HUANG Jihong HUANG Junwei FENG | 2015 | Agricultural Science & Technology2015，16，5： | 1 |
| 14 | Anisotropic diffusion for image de- noising based on diffusion tensors显示文摘 | Feng Liu Jingbo Liu | 2012 | Journal of Visual Communication and Image Representation2012，23，3： | 1 |
| 15 | A Method of Operational Effectiveness Evaluation of Integrated Communication Network Based on Fuzzy Synthetical Evaluation 显示文摘 | WANG Kai XIA Jingbo FENG Xin | 2009 | Computer Science2009，08，： | 1 |
| 16 | Cytokinin signaling promotes salt tolerance by modulating shoot chloride exclusion in maize显示文摘Excessive accumulation of chloride(Cl^(-))in the aboveground tissues under saline conditions is harmful to crops.Increasing the exclusion of Cl^(-) from shoots promotes salt tolerance in various crops.However,the underlying molecular mechanisms remain largely unknown.In this study,we demonstrated that a type A response regulator(ZmRR1)modulates Cl^(-) exclusion from shoots and underlies natural variation of salt tolerance in maize.ZmRR1 negatively regulates cytokinin signaling and salt tolerance,likely by interacting with and inhibiting His phosphotransfer(HP)proteins that are key mediators of cytokinin signaling.A naturally occurring non-synonymous SNP variant enhances the interaction between ZmRR1 and ZmHP2,conferring maize plants with a salt-hypersensitive phenotype.We found that ZmRR1 undergoes degradation under saline conditions,leading to the release of ZmHP2 from ZmRR1 inhibition,and subsequently ZmHP2-mediated signaling improves salt tolerance primarily by promoting Cl^(-) exclusion from shoots.Furthermore,we showed that ZmMATE29 is transcriptionally upregulated by ZmHP2-mediated signaling under highly saline conditions and encodes a tonoplast-located Cl^(-) transporter that promotes Cl^(-) exclusion from shoots by compartmentalizing Cl^(-) into the vacuoles of root cortex cells.Collectively,our study provides an important mechanistic understanding of the cytokinin signaling-mediated promotion of Cl^(-) exclusion from shoots and salt tolerance and suggests that genetic modification to promote Cl^(-) exclusion from shoots is a promising route for developing salt-tolerant maize. | Pan Yin Xiaoyan Liang Hanshu Zhao Zhipeng Xu Limei Chen Xiaohong Yang Feng Qin Jingbo Zhang Caifu Jiang | 2023 | Molecular Plant2023，16，6： | 1 |
| 17 | Anisotropic diffusion for image denoising based on diffusion tensors显示文摘 | Liu Feng Liu Jingbo | 2012 | Journal of Visual Communication and Image Representation2012，23，3： | 1 |
| 18 | Super enhancers:Pathogenic roles and potential therapeutic targets for acute myeloid leukemia(AML)显示文摘Acute myeloid leukemia(AML)is a malignant hematological tumor with disordered oncogenes/tumor suppressor genes and limited treatments.The potent anti-cancer effects of bromodomain and extra-terminal domain(BET)inhibitors,targeting the key component of super enhancers,in early clinical trials on AML patients,implies the critical role of super enhancers in AML.Here,we review the concept and characteristic of super enhancer,and then summarize the current researches about super enhancers in AML pathogenesis,diagnosis and classification,followed by illustrate the potential super enhancer-related targets and drugs,and propose the future directions of super enhancers in AML.This information provides integrated insight into the roles of super enhancers in this disease. | Ziyang Cao Yi Shu Jinxia Wang Chunxia Wang Tienan Feng Li Yang Jingbo Shao Lin Zou | 2022 | Genes & Diseases2022，9，6： | 1 |
| 19 | Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein显示文摘 | Zhipeng Yu Boqun Liu Wenzhu Zhao Yongguang Yin Jingbo Liu Feng Chen | 2012 | Food Chemistry2012，，2： | 1 |
| 20 | Effects of Anti-wind Erosion with Peanut Stubbles in Sandy Lands during Fallow Period 显示文摘 | Haixin WANG Jingbo YAN Huixin WANG Feng SHI | 2015 | Agricuhural &Technology2015，16，1： | 1 |
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