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| 1 | Editor’s note显示文摘Recent years see explosive data growth and rapid enhancement of computing powers.Under this background,file and storage technologies play a decisive role in business development and social progress,functioning as the master wand of diverse organizations,as well as a | ZHENG NanNing CHEN Lin WANG ChengHong HU ZhanYi XIN JingMin | 2011 | Science China(Information Sciences)2011，54，12： | 2 |
| 2 | Computationally efficient subspace-based method for two- dimensional direction estimation with L-shaped array 显示文摘 | Wang Guangmin Xin Jingmin Zheng Nanning | 2011 | IEEE Trans on Signal Process2011，59，7： | 1 |
| 3 | Integrating millimeter wave radar with a monocular vision sensor for on road obstacle detection applications 显示文摘 | WANG Tao ZHENG Nanning XIN Jingmin | 2011 | Sensors2011，11，9： | 1 |
| 4 | Linear prediction approach to di- rection estimation of cyclostationary signals in multipath en- vironment 显示文摘 | Jingmin Xin Akira Snao | 2001 | IEEE Transactions on Signal Processing2001，49，4： | 1 |
| 5 | Linear prediction approach to direction estimation of cyclostationary signals in multipath environment显示文摘 | Jingmin Xin Akira Sano | 2001 | IEEE Transactions on Signal Processing2001，49，4： | 1 |
| 6 | Fuzzy evaluation of powered support suitability to coal seams显示文摘 | Wenzhang Guo Jingmin Xin | 1990 | International Journal of Mining and Geological Engineering1990，，2： | 1 |
| 7 | Computationally efficient subspace-ba-sed method fortwo-dimensional direction estimation with L-shaped array显示文摘 | WANG Guangmin XIN Jingmin ZHENG Nanning etal | 2011 | IEEE Transactions on Signal Processing2011，59，7： | 1 |
| 8 | MSE-based regularization approach to direction estimation of coherent narrowband signals using linear prediction 显示文摘 | Jingmin Xin Sano A | 2001 | IEEE Trans on Signal Processing2001，49，11： | 1 |
| 9 | Human-Like Decision-Making of Autonomous Vehicles in Dynamic Traffic Scenarios显示文摘With the maturation of autonomous driving technology, the use of autonomous vehicles in a socially acceptable manner has become a growing demand of the public. Human-like autonomous driving is expected due to the impact of the differences between autonomous vehicles and human drivers on safety.Although human-like decision-making has become a research hotspot, a unified theory has not yet been formed, and there are significant differences in the implementation and performance of existing methods. This paper provides a comprehensive overview of human-like decision-making for autonomous vehicles. The following issues are discussed: 1) The intelligence level of most autonomous driving decision-making algorithms;2) The driving datasets and simulation platforms for testing and verifying human-like decision-making;3) The evaluation metrics of human-likeness;personalized driving;the application of decisionmaking in real traffic scenarios;and 4) The potential research direction of human-like driving. These research results are significant for creating interpretable human-like driving models and applying them in dynamic traffic scenarios. In the future, the combination of intuitive logical reasoning and hierarchical structure will be an important topic for further research. It is expected to meet the needs of human-like driving. | Tangyike Zhang Junxiang Zhan Jiamin Shi Jingmin Xin Nanning Zheng | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，10： | 0 |
| 10 | 基因组和转录组测序整合分析揭示混合型肝癌的不同分子亚型显示文摘文章简介原发性肝癌每年造成全球约70万病人死亡且过半死亡病例来自中国,其致死率在所有癌种中高居第二。肝癌主要分为3种类型:肝细胞癌(约80%)、肝内胆管癌(约15%)和混合型肝癌(约5%)。混合型肝癌兼具肝细胞癌和胆管细胞癌两种成分,是预后最差的一种肝癌。 | 薛瑞栋 陈璐 张冲 藤田征志 Ruoyan Li Shu-Mei Yan Choon Kiat Ong Xiwen Liao Qiang Gao Shota Sasagawa Yanmeng Li Jincheng Wang Hua Guo Qi-Tao Huang Qian Zhong Jing Tan Lisha Qi Wenchen Gong Zhixian Hong Meng Li Jingmin Zhao Tao Peng Yinying Lu Kiat Hon Tony Lim Arnoud Boot Atushi Ono Kazuaki Chayama Zemin Zhang Steve George Rozen Bin Tean Teh Xin Wei Wang Hidewaki Nakagawa 曾木圣 白凡 张宁 | 2020 | 科学新闻2020，，2： | 0 |
| 11 | Transcription factor ETV4 promotes the development of hepatocellular carcinoma by driving hepatic TNF-αsignaling显示文摘Background Hepatic inflammation is the major risk factor of hepatocellular carcinoma(HCC).However,the underlying mechanism by which hepatic inflammation progresses to HCC is poorly understood.This study was designed to investigate the role of ETS translocation variant 4(ETV4)in linking hepatic inflammation to HCC.Methods Quantitative real-time PCR and immunoblotting were used to detect the expression of ETV4 in HCC tissues and cell lines.RNA sequencing and luciferase reporter assays were performed to identify the target genes of ETV4.Hepatocyte-specific ETV4-knockout(ETV4fl/fl,alb-cre)and transgenic(ETV4Hep-TG)mice and diethylnitrosamine-carbon tetrachloride(DEN-CCL4)treatment experiments were applied to investigate the function of ETV4 in vivo.The Cancer Genome Atlas(TCGA)database mining and pathological analysis were carried out to determine the correlation of ETV4 with tumor necrosis factor-alpha(TNF-α)and mitogen-activated protein kinase 11(MAPK11).Results We revealed that ETV4 was highly expressed in HCC.High levels of ETV4 predicted a poor survival rate of HCC patients.Then we identified ETV4 as a transcription activator of TNF-αand MAPK11.ETV4 was positively correlated with TNF-αand MAPK11 in HCC patients.As expected,an increase in hepatic TNF-αsecretion and macrophage accumulation were observed in the livers of ETV4Hep-TG mice.The protein levels of TNF-α,MAPK11,and CD68 were significantly higher in the livers of ETV4Hep-TG mice compared with wild type mice but lower in ETV4fl/fl,alb-cre mice compared with ETV4fl/fl mice as treated with DEN-CCL4,indicating that ETV4 functioned as a driver of TNF-α/MAPK11 expression and macrophage accumulation during hepatic inflammation.Hepatocyte-specific knockout of ETV4 significantly prevented development of DEN-CCL4-induced HCC,while transgenic expression of ETV4 promoted growth of HCC.Conclusions ETV4 promoted hepatic inflammation and HCC by activating transcription of TNF-αand MAPK11.Both the ETV4/TNF-αand ETV4/MAPK11 axes represented two potential therapeutic targets for highly associated hepatic inflammation and HCC.ETV4+TNF-αwere potential prognostic markers for HCC patients. | Dandan Qi Min Lu Pengfei Xu Xinli Yao Yongchen Chen Lipeng Gan Yong Li Yahua Cui Xiaomei Tong Shuhong Liu Jingmin Zhao Ningning Liu Xin Ye | 2023 | Cancer Communications2023，43，12： | 0 |
| 12 | Improved Capon Estimator for High-Resolution DOA Estimation and Its Statistical Analysis显示文摘Despite some efforts and attempts have been made to improve the direction-of-arrival(DOA)estimation performance of the standard Capon beamformer(SCB)in array processing,rigorous statistical performance analyses of these modified Capon estimators are still lacking.This paper studies an improved Capon estimator(ICE)for estimating the DOAs of multiple uncorrelated narrowband signals,where the higherorder inverse(sample)array covariance matrix is used in the Capon-like cost function.By establishing the relationship between this nonparametric estimator and the parametric and classic subspace-based MUSIC(multiple signal classification),it is clarified that as long as the power order of the inverse covariance matrix is increased to reduce the influence of signal subspace components in the ICE,the estimation performance of the ICE becomes equivalent to that of the MUSIC regardless of the signal-to-noise ratio(SNR).Furthermore the statistical performance of the ICE is analyzed,and the large-sample mean-squared-error(MSE)expression of the estimated DOA is derived.Finally the effectiveness and the theoretical analysis of the ICE are substantiated through numerical examples,where the Cramer-Rao lower bound(CRB)is used to evaluate the validity of the derived asymptotic MSE expression. | Weiliang Zuo Jingmin Xin Changnong Liu Nanning Zheng Akira Sano | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，8： | 0 |
| 13 | Cellular gp96 upregulates AFP expression by blocking NR5A2 SUMOylation and ubiquitination in hepatocellular carcinoma显示文摘Alpha-fetoprotein (AFP) is the most widely used biomarker for the diagnosis of hepatocellular carcinoma (HCC). However, asubstantial proportion of HCC patients have either normal or marginally increased AFP levels in serum, and the underlyingmechanisms are not fully understood. In the present study, we provided in vitro and in vivo evidence that heat shock protein gp96promoted AFP expression at the transcriptional level in HCC. NR5A2 was identified as a key transcription factor for the AFP gene, andits stability was enhanced by gp96. A further mechanistic study by co-immunoprecipitation, GST pull-down, and molecular dockingshowed gp96 and the SUMO E3 ligase RanBP2 competitively binding to NR5A2 at the sites spanning from aa 507 to aa 539. Thebinding of gp96 inhibited SUMOylation, ubiquitination, and subsequent degradation of NR5A2. In addition, clinical analysis of HCCpatients indicated that gp96 expression in tumors was positively correlated with serum AFP levels. Therefore, our study uncovered anovel mechanism that gp96 regulates the stability of its client proteins by directly affecting their SUMOylation and ubiquitination.These findings will help in designing more accurate AFP-based HCC diagnosis and progression monitoring approaches. | Liyuan Qian Zhentao Liang Zihao Wang Jiuru Wang Xin Li Jingmin Zhao Zihai Li Lizhao Chen Yongai Liu Ying Ju Changfei Li Songdong Meng | 2023 | Journal of Molecular Cell Biology2023，15，5： | 0 |
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