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| 1 | Serrated polyps of the colon and rectum:Remove or not?显示文摘In recent years,the serrated neoplasia pathway where serrated polyps arise as a colorectal cancer has gained considerable attention as a new carcinogenic pathway.Colorectal serrated polyps are histopathologically classified into hyperplastic polyps(HPs),sessile serrated lesions,and traditional serrated adenomas;in the serrated neoplasia pathway,the latter two are considered to be premalignant.In western countries,all colorectal polyps,including serrated polyps,apart from diminutive rectosigmoid HPs are removed.However,in Asian countries,the treatment strategy for colorectal serrated polyps has remained unestablished.Therefore,in this review,we described the clinicopathological features of colorectal serrated polyps and proposed to remove HPs and sessile serrated lesions≥6 mm in size,and traditional serrated adenomas of any size. | Wataru Sano Daizen Hirata Akira Teramoto Mineo Iwatate Santa Hattori Mikio Fujita Yasushi Sano | 2020 | World Journal of Gastroenterology2020，26，19： | 12 |
| 2 | Effective use of the Japan Narrow Band Imaging Expert Team classification based on diagnostic performance and confidence level显示文摘Five years have passed since the Japan Narrow Band Imaging Expert Team (JNET) classification was proposed in 2014. However, the diagnostic performance of this classification has not yet been established. We conducted a retrospective study and a systematic search of Medical Literature Analysis and Retrieval System On-Line. There were three retrospective single center studies about the diagnostic performance of this classification. In order to clarify this issue, we reviewed our study and three previous studies. This review revealed the diagnostic performance in regards to three important differentiations.(1) Neoplasia from non-neoplasia;(2) malignant neoplasia from benign neoplasia;and (3) deep submucosal invasive cancer (D-SMC) from other neoplasia. The sensitivity in differentiating neoplasia from non-neoplasia was 98.1%-99.8%. The specificity in differentiating malignant neoplasia from benign neoplasia was 84.7%-98.2% and the specificity in the differentiation D-SMC from other neoplasia was 99.8%-100.0%. This classification would enable endoscopists to identify almost all neoplasia, to appropriately determine whether to perform en bloc resection or not, and to avoid unnecessary surgery. This article is the first review about the diagnostic performance of the JNET classification. Previous reports about the diagnostic performance have all been retrospective single center studies. A large-scale prospective multicenter evaluation study is awaited for the validation. | Daizen Hirata Hiroshi Kashida Mineo Iwatate Tomomasa Tochio Akira Teramoto Yasushi Sano Masatoshi Kudo | 2019 | World Journal of Clinical Cases2019，7，18： | 6 |
| 3 | High false-negative proportion of intraoperative histological examination as a serious problem for clinical application of sentinel node biopsy for early gastric cancer: final results of the Japan Clinical Oncology Group multicenter trial JCOG0302显示文摘 | Isao Miyashiro Masahiro Hiratsuka Mitsuru Sasako Takeshi Sano Junki Mizusawa Kenichi Nakamura Atsushi Nashimoto Akira Tsuburaya Norimasa Fukushima | 2014 | Gastric Cancer2014，，2： | 5 |
| 4 | Prospective real-time evaluation of diagnostic performance using endocytoscopy in differentiating neoplasia from nonneoplasia for colorectal diminutive polyps(≤ 5 mm)显示文摘AIM To clarify the diagnostic performance of endocytoscopy for differentiation between neoplastic and nonneoplastic colorectal diminutive polyps.METHODS Patients who underwent endocytoscopy between October and December 2016 at Sano Hospital were prospectively recruited. When diminutive polyps(≤5 mm) were detected, the lesions were evaluated by endocytoscopy after being stained with 0.05% crystal violet and 1% methylene blue. The diminutivepolyps were classified into five categories(EC 1 a, 1 b, 2, 3 a, and 3 b). Endoscopists were asked to take a biopsy from any lesion diagnosed as EC1 b(indicator of hyperplastic polyp) or EC2(indicator of adenoma). We have assessed the diagnostic performance of endocytoscopy for EC2 and EC1 b lesions by comparison with the histopathology of the biopsy specimen. RESULTS A total of 39 patients with 63 diminutive polyps were analyzed. All polyps were evaluated by endocytoscopy. The mean polyp size was 3.3 ± 0.9 mm. Among the 63 diminutive polyps, 60 were flat and 3 were pedunculated. The mean time required for EC observation, including the time for staining with crystal violet and methylene blue, was 3.0 ± 1.9 min. Histopathologic evaluation showed that 13 polyps were hyperplastic and 50 were adenomas. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of EC2 for adenoma compared with EC1 b for hyperplastic polyp were 98.0%, 92.3%, 96.8%, 98.0% and 92.3%, respectively. There were only two cases of disagreement between the endoscopic diagnosis made by endocytoscopy and the corresponding histopathological diagnosis.CONCLUSION Endocytoscopy showed a high diagnostic performance for differentiating between neoplastic and non-neoplastic colorectal diminutive polyps, and therefore has the potential to be used for 'real-time histopathology'. | Takahiro Utsumi Yasushi Sano Mineo Iwatate Hironori Sunakawa Akira Teramoto Daizen Hirata Santa Hattori Wataru Sano Noriaki Hasuike Kazuhito Ichikawa Takahiro Fujimori | 2018 | World Journal of Gastrointestinal Oncology2018，10，4： | 4 |
| 5 | Endoscopic ultrasound-guided biliary drainage for right hepatic bile duct obstruction: novel technical tips显示文摘 | Takeshi Ogura Tatsushi Sano Saori Onda Akira Imoto Daisuke Masuda Kazuhiro Yamamoto Masayuki Kitano Toshihisa Takeuchi Takuya Inoue Kazuhide Higuchi | 2014 | Endoscopy2014，，： | 3 |
| 6 | Non-alcoholic fatty liver disease later diagnosed as myotonic dystrophy显示文摘BACKGROUND Myotonic dystrophy(MD)is sometimes accompanied by metabolic/endocrine disorders,including dyslipidemia,central obesity,and hypogonadism.Due to considerable individual differences in the severity and progression of myopathy,MD patients with minimal-to-mild muscle symptoms might be followed as having other diseases,such as non-alcoholic fatty liver disease(NAFLD).CASE SUMMARY A 40-year-old non-obese man without a history of regular ethanol consumption was referred to our hospital due to persistent liver dysfunction and hyperlipidemia.His body mass index was 23.4 kg/m2.Liver histology demonstrated macrovesicular steatosis,ballooned hepatocytes with eosinophilic inclusion bodies,and perisinusoidal fibrosis,leading to the diagnosis of nonalcoholic steatohepatitis(NASH).Although he had no discernable muscle pain or weakness,persistently high serum creatine kinase(CK)and myoglobin levels as well as the presence of frontal baldness,a hatched face,history of cataract surgery,and grip myotonia indicated the possibility of MD.Southern blotting of the patient’s DNA revealed the presence of CTG repeats,confirming the diagnosis.CONCLUSION When gastroenterologists encounter NAFLD/NASH patients,serum CK should be verified.If hyperCKemia,frontal baldness,a hatched face,history of cataract surgery,and grip myotonia are noted,the possibility of MD may be considered. | Naoki Tanaka Takefumi Kimura Naoyuki Fujimori Yasuyuki Ichise Kenji Sano Akira Horiuchi | 2020 | World Journal of Hepatology2020，12，9： | 3 |
| 7 | Phase II trial of S-1 for neoadjuvant chemotherapy against scirrhous gastric cancer (JCOG 0002)显示文摘 | Taira Kinoshita Mitsuru Sasako Takeshi Sano Hitoshi Katai Hiroshi Furukawa Akira Tsuburaya Isao Miyashiro Masahide Kaji Motoki Ninomiya | 2009 | Gastric Cancer2009，，1： | 3 |
| 8 | Removal of small colorectal polyps in anticoagulated patients: a prospective randomized comparison of cold snare and conventional polypectomy显示文摘 | Akira Horiuchi Yoshiko Nakayama Masashi Kajiyama Naoki Tanaka Kenji Sano David Y. Graham | 2014 | Gastrointestinal Endoscopy2014，，3： | 3 |
| 9 | A Reversible Type of Neuronal Injury Following Ischemia in the Gerbil Hippocampus显示文摘 | TAKAAKJ KIRINO AKIRA TAMURA KEIJI SANO | 1986 | Stroke1986，，3： | 2 |
| 10 | Effects of reconstruction methods on a patient’s quality of life after a proximal gastrectomy: subjective symptoms evaluation using questionnaire survey显示文摘 | Masanori Tokunaga Naoki Hiki Shigekazu Ohyama Souya Nunobe Akira Miki Tetsu Fukunaga Yasuyuki Seto Takeshi Sano Toshiharu Yamaguchi | 2009 | Langenbeck’s Archives of Surgery2009，，4： | 1 |
| 11 | Highly Purified Eicosapentaenoic Acid Treatment Improves Nonalcoholic Steatohepatitis显示文摘 | Naoki Tanaka Kenji Sano Akira Horiuchi Eiji Tanaka Kendo Kiyosawa Toshifumi Aoyama | 2008 | Journal of Clinical Gastroenterology2008，，4： | 1 |
| 12 | Increased mRNA expression of cardiac renin-angiotensin system and collagen synthesis in spontaneously hypertensive rats显示文摘 | Hitoshi Sano Hitoshi Okamoto Akira Kitabatake Kenzi Iizuka Takeshi Murakami Hideaki Kawaguchi | 1998 | Molecular and Cellular Biochemistry (-)1998，，1： | 1 |
| 13 | Linear prediction approach to direction estimation of cyclostationary signals in multipath environment显示文摘 | Jingmin Xin Akira Sano | 2001 | IEEE Transactions on Signal Processing2001，49，4： | 1 |
| 14 | Influence of Overweight on Surgical Complications for Gastric Cancer: Results From a Randomized Control Trial Comparing D2 and Extended Para-aortic D3 Lymphadenectomy (JCOG9501)显示文摘 | Toshimasa Tsujinaka MD Mitsuru Sasako MD Seiichiro Yamamoto PhD Takeshi Sano MD Yukinori Kurokawa MD Atsushi Nashimoto MD Akira Kurita MD Hitoshi Katai MD Toshio Shimizu MD Hiroshi Furukawa MD Satoru Inoue MD Masahiro Hiratsuka MD Taira Kinoshita MD Kuniy | 2007 | Annals of Surgical Oncology2007，，2： | 1 |
| 15 | Autocalibration algorithm for robust capon beamforming显示文摘 | Shohei Kikuchi Hiroyuki Tsuji Akira Sano | 2006 | IEEE Antennas and Wireless Propagation Letters2006，，5： | 1 |
| 16 | Electric-field- assisted treatment of plasma-sprayed ZrO2 coatings 显示文摘 | Akira Ohmori Katsuyuki Aoki Saburo Sano | 1992 | Thin Solid Films1992，207，： | 1 |
| 17 | Generating novel memories by integration of chaotic neural network modules显示文摘 | Akira Sano | 2000 | Artificial Life and Robotics2000，，1： | 1 |
| 18 | Influence of Overweight on Surgical Complications for Gastric Cancer: Results From a Randomized Control Trial Comparing D2 and Extended Para-aortic D3 Lymphadenectomy (JCOG9501)显示文摘 | Toshimasa Tsujinaka MD Mitsuru Sasako MD Seiichiro Yamamoto PhD Takeshi Sano MD Yukinori Kurokawa MD Atsushi Nashimoto MD Akira Kurita MD Hitoshi Katai MD Toshio Shimizu MD Hiroshi Furukawa MD Satoru Inoue MD Masahiro Hiratsuka MD Taira Kinoshita MD Kuniy | 2007 | Annals of Surgical Oncology2007，，2： | 1 |
| 19 | Evaluation of an aspiration-type semiautomatic cutting biopsy needle显示文摘 | Atsushi Komemushi Shohei Kanno Satoshi Suzuki Akira Sano Shuji Kariya Miyuki Nakatani Rie Yagi Yoshida Yumiko Kono Yoko Harima Noboru Tanigawa | 2015 | Minimally Invasive Therapy & Allied Technologies2015，，4： | 1 |
| 20 | Stent length is impact factor associated with stent patency in endoscopic ultrasound‐guided hepaticogastrostomy显示文摘 | Takeshi Ogura Kazuhiro Yamamoto Tatsushi Sano Saori Onda Akira Imoto Daisuke Masuda Wataru Takagi Shinya Fukunishi Kazuhide Higuchi | 2015 | Journal of Gastroenterology and Hepatology2015，，12： | 1 |
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