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| 1 | Soil Microbial Population Dynamics along a Chronosequence of Moist Evergreen Broad-leaved Forest Succession in Southwestern China显示文摘Little is known about whether soil microbial population dynamics are correlated with forest succession.To test the hypotheses that(1) soil microbial composition changes over successional stages,and(2) soil microbial diversity is positively correlated with plant species diversity,we determined the soil microbial populations,community composition,and microflora diversity in evergreen broad-leaved forests along a chronosequence of vegetation succession from 5 to 300 years in southwestern China.The soil microbial community was mainly composed of bacteria(87.1-98.7% of the total microorganisms and 10 genera identified),fungi(0.3-4.0%,7 genera),and actinomycetes(2.1-9.1%,8 species and 1 genus).There were significant differences in soil microbial populations among different successional stages and within the four seasons.The seasonal variations of the soil microbial community may be associated with the seasonal changes in environmental conditions.The changes in soil microbial diversity(Shannon-Wiener index) with successional time followed one-humped,convex curves peaked at-100 years since restoration,which is identical with the trends of the aboveground plant diversity.Higher plant diversity resulting in enhanced nutrient flow and root exudation may contribute to positive relationships between the soil microbial diversity and plant diversity.Hence,decreases in soil microbial diversity in the late-successional stages appear to be related to the net loss in species richness that occurs after 100 years since restoration.Our findings confirm the intermediate disturbance hypothesis that suggests diversity peaks at midsuccessional stages. | ZHU Wanze CAI Xiaohu LIU Xingliang WANG Jinxi CHENG Song ZHANG Xiuyan LI Dengyu LI Maihe | 2010 | Journal of Mountain Science2010，7，4： | 8 |
| 2 | Whole genome sequencing of 10K patients with acute ischaemic stroke or transient ischaemic attack: design, methods and baseline patient characteristics显示文摘Background and purpose Stroke is the second leading cause of death worldwide and the leading cause of mortality and long-term disability in China,but its underlying risk genes and pathways are far from being comprehensively understood.We here describe the design and methods of whole genome sequencing(WGS)for 10914 patients with acute ischaemic stroke or transient ischaemic attack from the Third China National Stroke Registry(CNSR-III).Methods Baseline clinical characteristics of the included patients in this study were reported.DNA was extracted from white blood cells of participants.Libraries are constructed using qualified DNA,and WGS is conducted on BGISEQ-500 platform.The average depth is intended to be greater than 30×for each subject.Afterwards,Sentieon software is applied to process the sequencing data under the Genome Analysis Toolkit best practice guidance to call genotypes of single nucleotide variants(SNVs)and insertion-deletions.For each included subject,21 fingerprint SNVs are genotyped by MassARRAY assays to verify that DNA sample and sequencing data originate from the same individual.The copy number variations and structural variations are also called for each patient.All of the genetic variants are annotated and predicted by bioinformatics software or by reviewing public databases.Results The average age of the included 10914 patients was 62.2±11.3 years,and 31.4%patients were women.Most of the baseline clinical characteristics of the 10914 and the excluded patients were balanced.Conclusions The WGS data together with abundant clinical and imaging data of CNSR-III could provide opportunity to elucidate the molecular mechanisms and discover novel therapeutic targets for stroke. | Si Cheng Zhe Xu Yang Liu Jinxi Lin Yong Jiang Yilong Wang Xia Meng Anxin Wang Xinying Huang Zhimin Wang Guohua Chen Songdi Wu Zhengchang Jia Yongming Chen Xuerong Qiu Jun Wu Binbin Song Weizhong Ji Zhongping An Wenjun Xue Lili Zhao Yu Geng Hongyan Li Hao Li Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 8 |
| 3 | Variability of streambed vertical hydraulic conductivity with depth along the Elkhorn River,Nebraska,USA显示文摘Determination of streambed hydraulic conductivity is of great importance in the analysis of stream-aquifer interactions and stream ecosystems.In this paper,in situ falling-head standpipe permeameter tests were conducted to determine streambed vertical hydraulic conductivity (Kv) of two connected layers of sediments at 60 test locations from eight sites in the Elkhorn River,Nebraska.Our results show that the Kv values for the upper layer of sediments are generally larger than those in their respective lower layer of sediments.The individual Kv value for the upper layer of sediments from all test locations of the eight sites range from 2.7 to 104.9 m/d,and the average value is 26.6 m/d.The individual Kv value ranges from 0.4 to 73.4 m/d and the average value is 16.1 m/d for the lower layer of sediments.We believe that hyporheic processes can enhance larger streambed Kv in the upper layer of sediments.Inflow and outflow through hyporheic zone produce more porous and permeable sediments and further result in an increasing of streambed Kv.Moreover,we observe that bioturbation activities can destroy the clogging layer of the exposed sediments and create pore spaces in the sediments,which also further increases streambed Kv. | SONG JinXi CHEN XunHong CHENG Cheng WANG DeMing WANG WenKe | 2010 | Chinese Science Bulletin2010，55，10： | 2 |
| 4 | Observation of bioturbation and hyporheic flux in streambeds显示文摘In the Elkhorn River,burrows,tubes,and sediment mounds created by invertebrate bioturbation were observed in the exposed streambed and commonly concentrated on the fine-sediment patches,which consist of silt,clay,and organic matter.These invertebrate activities could loosen the thin layer of clogging sediments and result in an increase of pore size in the sediments,leading to greater vertical hydraulic conductivity of the streambed(Kv).The measurements of the vertical hydraulic gradient across the submerged streambed show that vertical flux in the hyporheic zone can alter directions(upward versus downward)for two locations only a few meters apart.In situ permeameter tests show that streambed Kv in the upper sediment layer is much higher than that in the lower sediment layer,and the calculated Kv in the submerged streambed is consistently greater than that in the clogged sediments around the shorelines of the sand bars.Moreover,a phenomenon of gas bubble release at the water-sediment interface from the subsurface sediments was observed in the groundwater seepage zone where flow velocity is extremely small.The bursting of gas bubbles can potentially break the thin clogging layer of sediments and enhance the vertical hydraulic conductivity of the streambed. | Jinxi SONG Xunhong CHEN Cheng CHENG | 2010 | Frontiers of Environmental Science & Engineering2010，4，3： | 2 |
| 5 | A new method for mapping variability in vertical seepage flux in streambeds显示文摘 | Xunhong Chen Jinxi Song Cheng Cheng Deming Wang Susan O. Lackey | 2009 | Hydrogeology Journal2009，，3： | 1 |
| 6 | Rapid and Efficient Adsorption Removal of Reactive Blue 4 from Aqueous Solution by Cross-Linked Microcrystalline Cellulose–Epichlorohydrin Polymers: Isothermal, Kinetic, and Thermodynamic Study显示文摘In this study, we modified microcrystalline cellulose by cross-linking it with epichlorohydrin to obtain a rapid and efficient adsorbent for the removal of Reactive Blue 4 dye from aqueous solution. Evidences of the cross-linking of the microcrystalline cellulose were obtained by Fourier transform infrared spectroscopy, X-ray diff raction, Brunauer–Emmett–Teller analysis, thermogravimetric analysis, and scanning electron microscopy. We investigated the eff ects of adsorbent dosage, p H, initial dye concentration, temperature, and contact time on the dye adsorption capacity. The results showed that the adsorption equilibrium time was just 20 min and the maximum adsorption capacity was 69.79 mg/g. The adsorption isotherm data fitted the Langmuir isotherm model well, and the adsorption kinetics data followed the pseudo-second-order kinetic model. The results of the thermodynamic analysis suggest that the adsorption process was spontaneous and exothermic. Recyclability experiments demonstrated the good reusability of this adsorbent. Electrostatic interaction was found to dominate the adsorption process. | Yuanyuan Zhai Hongmei Qu Zhongxuan Li Bo Zhang Jinxi Cheng Jiaji Zhang | 2021 | Transactions of Tianjin University2021，27，1： | 1 |
| 7 | Feasi-bility of grain-size analysis methods for determination ofvertical hydraulic conductivity of streambeds显示文摘 | Song Jinxi Chen Xunhong Cheng Cheng | 2009 | Jour-nal of Hydrology2009，375，34： | 1 |
| 8 | Feasibili- ty of grain-size analysis methods for determination of verti- cal hydraulic conductivity of streambeds 显示文摘 | Song Jinxi Chen Xunhong Cheng Cheng | 2009 | Journal of Hy- drology2009，375，3： | 1 |
| 9 | Micro–meso-macroporous FeCo-N-C derived from hierarchical bimetallic FeCo-ZIFs as cathode catalysts for enhanced Li-O2 batteries performance显示文摘Developing bifunctional catalysts that increase both the OER and ORR kinetics and transport reactants with high efficiency is desirable. Herein, micro–meso-macroporous FeCo-N-C-X(denoted as 'MFeCo-N-C-X', X represents Fe/Co molar ratio in bimetallic zeolite imidazole frameworks FeCo-ZIFs) catalysts derived from hierarchical M-FeCo-ZIFs-X was prepared. The micropores in M-FeCo-N-C-X have strong capability in O2 capture as well as dictate the nucleation and early-stage deposition of Li2O2,the mesopores provided a channel for the electrolyte wetting, and the macroporous structure promoted more available active sites when used as cathode for Li-O2 batteries. More importantly, M-Fe CoN-C-0.2 based cathode showed a high initial capacity(18,750 mAh g-1@0.1 A g-1), good rate capability(7900 m Ah g-1@0.5 A g-1), and cycle stability up to 192 cycles. Interestingly, the FeCo-N-C-0.2 without macropores suffered relatively poorer stability with only 75 cycles, although its discharge capacity was still as high as 17,200 mA h g-1(@0.1 A g-1). The excellent performance attributed to the synergistic contribution of homogeneous Fe, Co nanoparticles and N co-doping carbon frameworks with special micro–meso-macroporous structure. The results showed that hierarchical FeCo-N-C architectures are promising cathode catalysts for Li-O2 batteries. | Fufang Chao Baoxing Wang Jiaojiao Ren Yingwei Lu Wenrui Zhang Xizhang Wang Lin Cheng Yongbing Lou Jinxi Chen | 2019 | Journal of Energy Chemistry2019，28，8： | 1 |
| 10 | Biomarker and genomic analyses reveal molecular signatures of non-cardioembolic ischemic stroke显示文摘Acute ischemic stroke(AIS)is a major cause of disability and mortality worldwide.Non-cardioembolic ischemic stroke(NCIS),which constitutes the majority of AIS cases,is highly heterogeneous,thus requiring precision medicine treatments.This study aimed to investigate the molecular mechanisms underlying NCIS heterogeneity.We integrated data from the Third China National Stroke Registry,including clinical phenotypes,biomarkers,and whole-genome sequencing data for 7695 patients with NCIS.We identified 30 molecular clusters based on 63 biomarkers and explored the comprehensive landscape of biological heterogeneity and subpopulations in NCIS.Dimensionality reduction revealed fine-scale subpopulation structures associated with specific biomarkers.The subpopulations with biomarkers for inflammation,abnormal liver and kidney function,homocysteine metabolism,lipid metabolism,and gut microbiota metabolism were associated with a high risk of unfavorable clinical outcomes,including stroke recurrence,disability,and mortality.Several genes encoding potential drug targets were identified as putative causal genes that drive the clusters,such as CDK10,ERCC3,and CHEK2.We comprehensively characterized the genetic architecture of these subpopulations,identified their molecular signatures,and revealed the potential of the polybiomarkers and polygenic prediction for assessing clinical outcomes.Our study demonstrates the power of large-scale molecular biomarkers and genomics to understand the underlying biological mechanisms of and advance precision medicine for NCIS. | Lingling Ding Yu Liu Xia Meng Yong Jiang Jinxi Lin Si Cheng Zhe Xu Xingquan Zhao Hao Li Yongjun Wang Zixiao Li | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 0 |
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