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| 1 | A conodont-based Middle Triassic age assignment for the Luoping Biota of Yunnan, China显示文摘The Luoping Biota consists of abundant and well-preserved marine fishes, reptiles, invertebrates, and plants. It occurs in the Middle Triassic Guanling Formation in Daaozi Village of Luoping County, Yun-nan Province, China. Based on conodonts, the Luoping Biota is determined to lie within the Nicoraella kockeli Zone, which is assigned to the Pelsonian substage of the Anisian. | ZHANG QiYue ZHOU ChangYong LU Tao XIE Tao LOU XiongYing LIU Wei SUN YuanYuan HUANG JinYuan ZHAO LaiShi | 2009 | Science China Earth Sciences2009，52，10： | 15 |
| 2 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 3 | Cloning and sequence characteristics of the genomic gene of a rice metallothionein显示文摘Northern blot analysis showed that a metallothionein gene, ricMT is expressed strongly in the stem of rice with an expression level that could be more than 100-fold stronger than in leaf blades. The results suggest that the 5’ upstream region flanking the coding sequence of the ricMT may contain a fairly strong promoter To elucidatr its regulation and promoter structure, the genomic clones of ricMT were screened out from a rice genomic library and a fragment of about 4084 bp was sequenced. The fragment included a 5’ upstream region of ca. 2970 bp, a transcription region of ca. 690 bp and a 3’ downstream region of ca. 420 bp. Computer analysis of the sequence homology showed that the 5’ upstream region included a putative TATA box, a putative CAAT box, and a typical metal-responsive element TGCGCGCG. The results will promote further understanding of the mechanisms of gene regulation and metal response of plant metallothionein proteins. | YU Lihua, LIU Jinyuan, Masaaki Umeda, Hirofumi Uchimiya & ZHAO Nanming Department of Biological Sciences and Biotechnology, State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing 100084, China Institute of Molecular and Cellular Bioscie | 2000 | Chinese Science Bulletin2000，45，2： | 4 |
| 4 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 5 | Accelerating Packet Classification with Counting Bloom Filters for Virtual Open Flow Switching显示文摘The growing trend of network virtualization results in a widespread adoption of virtual switches in virtualized environments. However, virtual switching is confronted with great performance challenges regarding packet classification especially in Open Flow-based software defined networks. This paper first takes an insight into packet classification in virtual Open Flow switching, and points out that its performance bottleneck is dominated by flow table traversals of multiple failed mask probing for each arrived packet. Then we are motivated to propose an efficient packet classification algorithm based on counting bloom filters. In particular, counting bloom filters are applied to predict the failures of flow table lookups with great possibilities, and bypass flow table traversals for failed mask probing. Finally, our proposed packet classification algorithm is evaluated with real network traffic traces by experiments. The experimental results indicate that our proposed algorithm outperforms the classical one in Open v Switch in terms of average search length, and contributes to promote virtual Open Flow switching performance. | Jinyuan Zhao Zhigang Hu Bing Xiong Keqin Li | 2018 | China Communications2018，15，10： | 2 |
| 6 | Recent Advances in Molybdenum-Based Materials for Lithium-Sulfur Batteries显示文摘Lithium-sulfur(Li-S)batteries as power supply systems possessing a theoretical energy density of as high as 2600 Wh kg−1 are considered promising alternatives toward the currently used lithium-ion batteries(LIBs).However,the insulation characteristic and huge volume change of sulfur,the generation of dissolvable lithium polysulfides(LiPSs)during charge/discharge,and the uncontrollable dendrite formation of Li metal anodes render Li-S batteries serious cycling issues with rapid capacity decay.To address these challenges,extensive efforts are devoted to designing cathode/anode hosts and/or modifying separators by incorporating functional materials with the features of improved conductivity,lithiophilic,physical/chemical capture ability toward LiPSs,and/or efficient catalytic conversion of LiPSs.Among all candidates,molybdenum-based(Mo-based)materials are highly preferred for their tunable crystal structure,adjustable composition,variable valence of Mo centers,and strong interactions with soluble LiPSs.Herein,the latest advances in design and application of Mo-based materials for Li-S batteries are comprehensively reviewed,covering molybdenum oxides,molybdenum dichalcogenides,molybdenum nitrides,molybdenum carbides,molybdenum phosphides,and molybdenum metal.In the end,the existing challenges in this research field are elaborately discussed. | Henghan Dai Lumin Wang Yue Zhao Jialu Xue Ruicong Zhou Chenyang Yu Jianing An Jinyuan Zhou Qiang Chen Gengzhi Sun Wei Huang | 2021 | Research2021，，1： | 1 |
| 7 | Mesh-like vertical structures enable both high areal capacity and excellent rate capability显示文摘In order to balance electrochemical kinetics with loading level for achieving efficient energy storage with high areal capacity and good rate capability simultaneously for wearable electronics,herein,2 D meshlike vertical structures(NiCo_2 S_4@Ni(OH)_2) with a high mass loading of 2.17 mg cm^(-2) and combined merits of both 1 D nanowires and 2 D nanosheets are designed for fabricating flexible hybrid supercapacitors.Particularly,the seamlessly interconnected NiCo_2 S_4 core not only provides high capacity of 287.5 μAh cm^(-2) but also functions as conductive skeleton for fast electron transport;Ni(OH)_2 sheath occupying the voids in NiCo_2 S_4 meshes contributes extra capacity of 248.4 μAh cm^(-2);the holey features guarantee rapid ion diffusion along and across NiCO_2 S_4@Ni(OH)_2 meshes.The resultant flexible electrode exhibits a high areal capacity of 535.9 μAh cm^(-2)(246.9 mAh g^(-1)) at 3 mA cm^(-2) and outstanding rate performance with 84.7% retention at 30 mA cm^(-2),suggesting efficient utilization of both NiCo_2 S_4 and Ni(OH)_2 with specific capacities approaching to their theoretical values.The flexible solid-state hybrid device based on NiCo_2 S_4@Ni(OH)_2 cathode and Fe_2 O_3 anode delivers a high energy density of 315 μWh cm^(-2) at the power density of 2.14 mW cm^(-2) with excellent electrochemical cycling stability. | Ruyi Chen Jialu Xue Yujiao Gong Chenyang Yu Zengyu Hui Hai Xu Yue Sun Xi Zhao Jianing An Jinyuan Zhou Qiang Chen Gengzhi Sun Wei Huang | 2021 | Journal of Energy Chemistry2021，30，2： | 1 |
| 8 | In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection 显示文摘 | Chen Jinyuan Dong Xia Zhao Jing | 2009 | J Appl Toxicol2009，29，4： | 1 |
| 9 | Modeling of kiwifruit metallothionein kiwi503显示文摘Kiwifruit metallothionein, kiwi503, is a typical plant metallothionein protein. It has 63 amino acid residues in two cysteine-rich regions and one spacer region of about 32 residues. In this note, the two cysteine-rich regions and the spacer region have been modeled separately by the distance geometry and the homology method. The three parts are then connected to generate a three-dimensional structural model of kiwifruit metallothionein kiwi503. The result shows that there is no structural or energy barrier preventing either cysteine rich domain from independently forming a metal-sulfur chelating cluster. The method can also be applied to predicting the structures of the same type of other proteins. | Chunming Zhu Tun Lü Riqing Zhang Nanming Zhao Jinyuan Liu | 2000 | Chinese Science Bulletin2000，45，15： | 1 |
| 10 | Enhancement of the Photocatalytic Oxygen Production by Tantalum Nitride Supported Fe Atom Embedded N-Doped Graphene Oxide显示文摘Energy crises and environmental pollution have become urgent problems with human civilization development.Photocatalysis technology is a green method to deal with these challenges.The key to improve photocatalytic efficiency lies in the effective separation of photogenerated electron-hole pairs.In this work,we designed the Fe atom embedded N-doped graphene oxide(Fe-NGO)supporting on tantalum nitride(Ta_(3)N_(5))catalyst,which was employed to improve the photocatalytic oxygen production activity.The oxygen production of 5 wt%Fe atom embedded N-doped graphene oxide supporting on tantalum nitride(Fe-NGO/Ta_(3)N_(5))was 184.7μmol·g^(-1),about 3.5 times higher than that of the pure Ta_(3)N_(5).The introduction of the cocatalyst Fe-NGO acting as an electron conductor in the Fe-NGO/Ta_(3)N_(5) accelerates the carrier migration of Ta_(3)N_(5) and further enhances the photocatalytic oxygen production activity.N-doping increases the conductivity of graphene oxide(GO),and Fe atoms are used as the reactive sites to promote the combination of electron and sacrificial agent in the system.This work may provide insights into the research of new carbon. | Hanxiang Chen Jia Yan Zhao Mo Jinyuan Liu Xianglin Zhu Huaming Li Hui Xu | 2023 | Chinese Journal of Chemistry2023，41，3： | 0 |
| 11 | Two-stage Correction Strategy-based Real-time Dispatch for Economic Operation of Microgrids显示文摘Given the different energy rates of multiple types of power generation units,different operation plans affect the economy of microgrids.Limited by load and power generation forecasting technologies,the economic superiority of day-ahead plans is unable to be fully utilized because of the fluctuation of loads and power sources.In this regard,a two-stage correction strategy-based real-time dispatch method for the economic operation of microgrids is proposed.Based on the optimal day-ahead economic operation plan,unbalanced power is validly allocated in two stages in terms of power increment and current power,which maintains the economy of the day-ahead plan.Further,for operating point offset during real-time correction,a rolling dispatch method is introduced to dynamically update the system operation plan.Finally,the results verify the effectiveness of the proposed method. | Jingliao Sun Changhong Hu Lei Liu Bei Zhao Jinyuan Liu Jianquan Shi | 2022 | Chinese Journal of Electrical Engineering2022，8，2： | 0 |
| 12 | A Visualized Fusion Protein Based on Self-assembly Hydrophobin HGFI显示文摘 | ZHAO Liqiang LIU Jinyuan SONG Dongmin WANG Xiangxiang TAI Feifei XU Haijin QIAO Mingqiang | 2015 | Chemical Research in Chinese Universities2015，31，5： | 0 |
| 13 | Preparation of the selenome-thionine derivative of tab-toxin resistance protein显示文摘In order to obtain phase information for the X-ray diffraction of tabtoxin resistance protein (TTR) crystal using the MAD phasing method, a selenomethionine (Se-Met) derivative of TTR was overexpressed in E. coli strain M15, with pQE-30 plasmid, through IPTG induction in M9 medium containing Se-Met. The product was purified to an estimated homogeneity of greater than 95% according to SDS-PAGE, by a Ni-NTA metal affinity followed by a Mono Q anion exchange column chromatography. The successful substitution of Se-Met for methionine (Met) was confirmed by MALDI-TOF and ESI-Quadrupole Mass Spectrometry analysis. The derivative crystal was obtained using similar conditions as those for the native. | HE Hongzhen SHAO Yu CHEN Yuhang LIU Bingbing CAO Zhenbo JIANG Fan LIU Yiwei TANG Hong LIU Jinyuan ZHAO Nanming RAO Zihe | 2001 | Chinese Science Bulletin2001，46，15： | 0 |
| 14 | Efficacy and safety of direct-acting antiviral agent regimens in a real-world cohort of adult Chinese patients with chronic hepatitis C virus infection显示文摘Background and aims:To investigate the safety and efficacy of direct-acting antiviral(DAA)regimens in a cohort of Chinese patients with chronic hepatitis C virus(HCV)infection.Methods:A total of 222 adult Chinese patients were enrolled and treated via DAA regimens in accor-dance with HCV management guidelines.Treatment responses were evaluated 4 weeks after treatment,at the end of treatment(EOT)and 12 weeks post-treatment.Virological responses,biochemical re-sponses,model for end-stage liver disease(MELD)and Child-Pugh(CP)scores were recorded.Results:A total of 218 patients(98.2%)achieved sustained virological response 12 weeks post-treatment and 4 patients relapsed.The combined number of rapid virological responses for all six regimens was 170/222(76.6%),and 221/222(99.6%)had achieved virological responses by the end of treatment.In decompensated cirrhosis patients the baseline mean CP score was 6.8±1.3 and the mean MELD score was 10.1±3.3.Compared with the mean CP score at baseline,the mean score is significantly lower at the end of treatment(5.7±1.3)and 12 weeks post-treatment(5.6±1.0).Estimated glomerular filtration rates did not differ significantly from baseline during the treatment or 12 weeks post-treatment.The incidence of adverse events in patients with chronic hepatitis C and compensated cirrhosis was 42/172(24.4%),and in patients with decompensated cirrhosis it was 8/22(36.4%).The most frequently reported adverse events were elevated indirect bilirubin,fatigue and rash.There were no cases of serious adverse events,death or treatment discontinuation because of adverse events.Conclusion:DAA regimens were highly effective and well tolerated irrespective of HCV genotype,cirrhosis,liver or kidney transplantation,hepatocellular carcinoma,HCV/hepatitis B virus co-infection,or renal failure. | Jinyuan Wei Yongyu Mei Jianping Li Jing Yuan Xiaohua Yang Zhen Xu Guoli Lin Juan Zhang Zhixin Zhao Xiaohong Zhang | 2020 | Liver Research2020，4，2： | 0 |
| 15 | Identification of the candidate gene controlling tiller angle in common wheat through genome-wide association study and linkage analysis显示文摘Wheat tiller angle(TA)is an important agronomic trait that contributes to grain production by affecting plant architecture.It also plays a crucial role in high-yield wheat breeding.An association panel and a recombinant inbred line(RIL)population were used to map quantitative trait loci(QTL)for TA.Results showed that 470 significant SNPs with 10.4%–28.8%phenotypic variance explained(PVE)were detected in four replicates by a genome-wide association study(GWAS).Haplotype analysis showed that the TA_Hap_4B1 locus on chromosome 4B was a major QTL to regulate wheat TA.Ten QTL were totally detected by linkage mapping with the RIL population,and QTA.hau-4B.1 identified in six environments with the PVE of 7.88%–18.82%was a major and stable QTL.A combined analysis demonstrated that both TA_Hap_4B1 and QTA.hau-4B.1 were co-located on the same region.Moreover,QTA.hau-4B.1 was confirmed by bulked segregant RNA-Seq(BSR-Seq)analysis.Phenotypic analysis showed that QTA.hau-4B.1was also closely related to yield traits.Furthermore,Traes CS4B02G049700 was considered as a candidate gene through analysis of gene sequence and expression.This study can be potentially used in cloning key genes modulating wheat tillering and provides valuable genetic resources for improvement of wheat plant architecture. | Lei Zhao Canguan Wang Tongzhu Wang Jinyuan Liu Qi Qiao Yulu Yang Pengyu Hu Leilei Zhang Simin Zhao Daiying Chen Yan Ren Ning Zhang Zhongdong Dong Feng Chen | 2023 | The Crop Journal2023，11，3： | 0 |
| 16 | Accelerating hybrid and compact neural networks targeting perception and control domains with coarse-grained dataflow reconfiguration显示文摘Driven by continuous scaling of nanoscale semiconductor technologies,the past years have witnessed the progressive advancement of machine learning techniques and applications.Recently,dedicated machine learning accelerators,especially for neural networks,have attracted the research interests of computer architects and VLSI designers.State-of-the-art accelerators increase performance by deploying a huge amount of processing elements,however still face the issue of degraded resource utilization across hybrid and non-standard algorithmic kernels.In this work,we exploit the properties of important neural network kernels for both perception and control to propose a reconfigurable dataflow processor,which adjusts the patterns of data flowing,functionalities of processing elements and on-chip storages according to network kernels.In contrast to stateof-the-art fine-grained data flowing techniques,the proposed coarse-grained dataflow reconfiguration approach enables extensive sharing of computing and storage resources.Three hybrid networks for MobileNet,deep reinforcement learning and sequence classification are constructed and analyzed with customized instruction sets and toolchain.A test chip has been designed and fabricated under UMC 65 nm CMOS technology,with the measured power consumption of 7.51 mW under 100 MHz frequency on a die size of 1.8×1.8 mm^2. | Zheng Wang Libing Zhou Wenting Xie Weiguang Chen Jinyuan Su Wenxuan Chen Anhua Du Shanliao Li Minglan Liang Yuejin Lin Wei Zhao Yanze Wu Tianfu Sun Wenqi Fang Zhibin Yu | 2020 | Journal of Semiconductors2020，41，2： | 0 |
| 17 | Research and Analysis of Cooling System for Diesel Locomotive显示文摘With the continuous development of diesel locomotives in the direction of single power, the heat dissipation of the locomotive cooling system is getting bigger and bigger, and its performance directly affects the economy and reliability of the locomotive. Due to the limitation of locomotive axle load and structural space size, there is a great technical problem between the cooling system design and the arrangement of the cooling device and the overall layout of the locomotive. The increase in the number of radiators, making the number of cooling system processes are correspondingly increased, resulting in locomotive cooling system water resistance and water system pressure are greatly improved. The traditional cooling system form and the radiator structure are diffi cult to meet the development requirements of high power locomotive. Based on the conventional cooling system design method, a multi-process radiator is proposed. The multi-process cooling system has the advantages of high cooling effi ciency, simple structure, small auxiliary power consumption of the pump and high reliability of the cooling system components. In this paper, the cooling system and its function, the existing cooling technology and the multi-process radiator are studied and analyzed, and the three-process radiator and the single-process radiator are tested and compared. In this paper, a new multi-process radiator structure scheme is proposed for the design requirements of CKD9 diesel locomotive cooling system. The program eff ectively uses the radiator cooling water and cooling air temperature diff erence, to achieve the purpose of increasing heat dissipation. | Wenbin Qiu Qiyuan Yu Jinyuan Zhao | 2018 | Progress of Electrical and Electronic Engineering2018，1，1： | 0 |
| 18 | Constructing boronate-bridged core-satellite gold nanoassembly and its application in high sensitive colorimetric detection of benzoyl peroxide residues in food matrices显示文摘Here,a new designed core/satellite gold nanoprobe was developed for detecting trace mount of benzoyl peroxide(BPO) based on its deboronation.This gold nanoassembly(the BE-Au NPs_(12/65)) wa s constructed via borate ester formation between large 4-mercaptophenylboronic acid(MPBA) modified Au NPs(the MPBAAu NPs_(65),as cores) and small dopamine modified AuNPs(the D PA-AuNPs_(12),as satellites).Particularly,upon addition of BPO,it would trigger the deboronation for the BE-AuNPs_(12/65) probes accompanying with distinct color changes from blue,purple to wine red,which implied the disassembly of the core/satellite nanostructure after the breakage of carbon to boron chemical bond.By measuring the absorbance ratio at 665 nm and 545 nm,quantification of BPO was achieved in the range of 10.0-100.0 nmol/L,which could also be easily observed by naked eyes.The nanoprobe utilized a boronate deprotection mechanism and the LSPR properties of Au NPs to provide high selectivity for detecting BPO over similar ROS/RNS with the limit of detection as low as 7.2 nmol/L.The practical applicability of this assay was verified through successful determining BPO in flour samples,which demonstrated its great potentials in food safety field. | Ting Li Jiefang Sun Jinyuan Liu Baolei Dong Huachao Zhao Xiaoting Qiao Wencong Shan Jing Zhang Bing Shao | 2020 | Chinese Chemical Letters2020，31，2： | 0 |
| 19 | Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management显示文摘Despite growing prevalence and incidence,the management of gout remains suboptimal.The intermittent nature of the gout makes the long-term urate-lowering therapy(ULT)particularly important for gout management.However,patients are reluctant to take medication day after day to manage incurable occasional gout flares,and suffer from possible long-term toxicity.Therefore,a safe and easy-tooperate drug delivery system with simple preparation for the long-term management of gout is very necessary.Here,a chitosan-containing sustained-release microneedle system co-loaded with colchicine and uricase liposomes were fabricated to achieve this goal.This microneedle system was confirmed to successfully deliver the drug to the skin and maintain a one-week drug retention.Furthermore,its powerful therapeutic potency to manage gout was investigated in both acute gouty and chronic gouty models.Besides,the drug co-delivery system could help avoid long-term daily oral colchicine,a drug with a narrow therapeutic index.This system also avoids mass injection of uricase by improving its stability,enhancing the clinical application value of uricase.In general,this two-drug system reduces the dosage of uricase and colchicine and improves the patient’s compliance,which has a strong clinical translation. | Yao Yang Zimu Li Ping Huang Jiachan Lin Jinyuan Li Kexin Shi Jiahui Lin Jingwen Hu Zhuoxian Zhao Yongkang Yu Hongzhong Chen Xiaowei Zeng Lin Mei | 2023 | Acta Pharmaceutica Sinica B2023，13，8： | 0 |
| 20 | The Jahn-Teller Effect for Amorphization of Molybdenum Trioxide towards High-Performance Fiber Supercapacitor显示文摘Amorphous pseudocapacitive nanomaterials are highly desired in energy storage applications for their disordered crystal structures,fast electrochemical dynamics,and outstanding cyclic stability,yet hardly achievable using the state-of-the-art synthetic strategies.Herein,for the first time,high capacitive fiber electrodes embedded with nanosized amorphous molybdenum trioxide(A-MoO_(3)-x)featuring an average particle diameter of~20 nm and rich oxygen vacancies are obtained via a top-down method usingα-MoO_(3)bulk belts as the precursors.The Jahn-Teller distortion in MoO_(6)octahedra due to the doubly degenerate ground state of Mo5+,which can be continuously strengthened by oxygen vacancies,triggers the phase transformation ofα-MoO_(3)bulk belts(up to 30μm long and 500 nm wide).The optimized fibrous electrode exhibits among the highest volumetric performance with a specific capacitance(CV)of 921.5 F cm^(-3)under 0.3 A cm^(-3),endowing the fiber-based weaveable supercapacitor superior CV and EV(energy density)of 107.0 F cm^(-3)and 9.5 mWh cm^(-3),respectively,together with excellent cyclic stability,mechanical robustness,and rate capability.This work demonstrates a promising strategy for synthesizing nanosized amorphous materials in a scalable,cost-effective,and controllable manner. | Chenyang Yu Hai Xu Yujiao Gong Ruyi Chen Zengyu Hui Xi Zhao Yue Sun Qiang Chen Jinyuan Zhou Wenxin Ji Gengzhi Sun Wei Huang | 2021 | Research2021，，1： | 0 |
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