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| 1 | Passive technologies for future large-scale photonic integrated circuits on silicon: polarization handling, light non-reciprocity and loss reduction显示文摘Silicon-based large-scale photonic integrated circuits are becoming important,due to the need for higher complexity and lower cost for optical transmitters,receivers and optical buffers.In this paper,passive technologies for large-scale photonic integrated circuits are described,including polarization handling,light non-reciprocity and loss reduction.The design rule for polarization beam splitters based on asymmetrical directional couplers is summarized and several novel designs for ultra-short polarization beam splitters are reviewed.A novel concept for realizing a polarization splitter–rotator is presented with a very simple fabrication process.Realization of silicon-based light non-reciprocity devices(e.g.,optical isolator),which is very important for transmitters to avoid sensitivity to reflections,is also demonstrated with the help of magneto-optical material by the bonding technology.Low-loss waveguides are another important technology for large-scale photonic integrated circuits.Ultra-low loss optical waveguides are achieved by designing a Si3N4 core with a very high aspect ratio.The loss is reduced further to,0.1 dB m21 with an improved fabrication process incorporating a high-quality thermal oxide upper cladding by means of wafer bonding.With the developed ultra-low loss Si3N4 optical waveguides,some devices are also demonstrated,including ultra-high-Q ring resonators,low-loss arrayed-waveguide grating(de)multiplexers,and high-extinction-ratio polarizers. | Daoxin Dai Jared Bauters John E Bowers | 2012 | Light(Science & Applications)2012，1，1： | 28 |
| 2 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 3 | Cost analysis of open and laparoscopic pancreaticoduodenectomy: a single institution comparison显示文摘 | Marc G. Mesleh John A. Stauffer Steven P. Bowers Horacio J. Asbun | 2013 | Surgical Endoscopy2013，，12： | 3 |
| 4 | Splenic Artery Aneurysms: Two Decades Experience at Mayo Clinic显示文摘 | Maher A. Abbas William M. Stone Richard J. Fowl Peter Gloviczki W. Andrew Oldenburg Peter C. Pairolero John W. Hallett Thomas C. Bower Jean M. Panneton Kenneth J. Cherry | 2002 | Annals of Vascular Surgery2002，，： | 2 |
| 5 | Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial显示文摘 | John Primrose Stephen Falk Meg Finch-Jones Juan Valle Derek O’Reilly Ajith Siriwardena Joanne Hornbuckle Mark Peterson Myrddin Rees Tim Iveson Tamas Hickish Rachel Butler Louise Stanton Elizabeth Dixon Louisa Little Megan Bowers Sian Pugh O James Garden D | 2014 | Lancet Oncology2014，，6： | 2 |
| 6 | CYBERKNIFE RADIOSURGERY FOR TRIGEMINAL NEURALGIA TREATMENT: A PRELIMINARY MULTICENTER EXPERIENCE显示文摘 | Alan T. Villavicencio Michael Lim Sigita Burneikiene Pantaleo Romanelli John R. Adler Lee McNeely Steven D. Chang Laura Fariselli Melinda McIntyre Regina Bower Giovanni Broggi Jeffrey J. Thramann | 2008 | Neurosurgery2008，，3： | 1 |
| 7 | The Sorghum bicolor genome and the diversification of grasses 显示文摘 | Andrew H Paterson John E Bowers Remy Bruggmann | 2009 | Nature2009，457，： | 1 |
| 8 | The syntax of predication 显示文摘 | Bowers John | 1993 | Linguistic Inquiry1993，24，： | 1 |
| 9 | Transitivity 显示文摘 | Bowers John | 2002 | Linguistic Inquiry2002，33，： | 1 |
| 10 | The syntax of predication 显示文摘 | Bowers John | 1993 | Linguistic lnquiry1993，，24： | 1 |
| 11 | A comparative phyloge-netic approach for dating whole genome duplication events 显示文摘 | CHAPMAN Brad A BOWERS John SCHULZE Stefan | 2004 | Bioinformatics2004，20，2： | 1 |
| 12 | Hepatic Microcirculatory Changes After Reperfusion In Fatty And Normal Liver TrANSPLANTATION IN THE RAT显示文摘 | Kenichi Teramoto John L. Bowers Jonathan B. Kruskal Melvin E. Clouse | 1993 | Transplantation1993，，5： | 1 |
| 13 | Reversal of endocardial endothelial dysfunction by folic acid in homocysteinemic hypertensive rats显示文摘 | Amanda Miller Vibhas Mujumdar Lena Palmer John D Bower Suresh C Tyagi | 2002 | American Journal of Hypertension2002，，2： | 1 |
| 14 | The role of intravenous fluorescein in the detection of colon ischemia during aortic reconstruction显示文摘 | R. Thomas Bergman MD Peter Gloviczki MD Timothy J. Welch MD James M. Naessens MPH Thomas C. Bower MD John W. Hallett MD Peter C. Pairolero MD Kenneth J. Cherry MD | 1992 | Annals of Vascular Surgery1992，，1： | 1 |
| 15 | The syntax of predication显示文摘 | Bowers John | 1993 | Linguistic Inquiry1993，，24： | 1 |
| 16 | Brachiocephalic aneurysm: The case for early recognition and repair显示文摘 | Thomas C. Bower Peter C. Pairolero John W. Hallett Barbara J. Toomey Peter Gloviczki Kenneth J. Cherry | 1991 | Annals of Vascular Surgery1991，，： | 1 |
| 17 | Contemporary management of acute mesenteric ischemia: Factors associated with survival显示文摘 | Woosup M. Park Peter Gloviczki Kenneth J. Cherry John W. Hallett Thomas C. Bower Jean M. Panneton Cathy Schleck Duane Ilstrup William S. Harmsen Audra A. Noel | 2002 | Journal of Vascular Surgery2002，，3： | 1 |
| 18 | Delayed Intraocular Foreign Body Removal without Endophthalmitis during Operations Iraqi Freedom and Enduring Freedom显示文摘 | Marcus H. Colyer Eric D. Weber Eric D. Weichel John S.B. Dick Kraig S. Bower Thomas P. Ward Julia A. Haller | 2007 | Ophthalmology2007，，8： | 1 |
| 19 | Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans显示文摘 | John H. Krystal Laurence P. Karper Alexandre Bennett D. Cyril D’Souza Anissa Abi-Dargham Kristen Morrissey Danielle Abi-Saab J. Douglas Bremner M. B. Bowers Jr. Raymond F. Suckow Philip Stetson George R. Heninger Dennis S. Charney | 1998 | Psychopharmacology1998，，3： | 1 |
| 20 | Population-based surveillance for acute liver failure 显示文摘 | BOWER W A JOHNS M MARGOLIS H S | 2007 | Am J Gastroenterol2007，102，： | 1 |
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