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| 1 | Comparative study of the transfection efficiency of commonly used viral vectors in rhesus monkey (Macaca mulatta) brains显示文摘Viral vector transfection systems are among the simplest of biological agents with the ability to transfer genes into the central nervous system.In brain research,a series of powerful and novel gene editing technologies are based on these systems.Although many viral vectors are used in rodents,their full application has been limited in non-human primates.To identify viral vectors that can stably and effectively express exogenous genes within nonhuman primates,eleven commonly used recombinant adeno-associated viral and lentiviral vectors,each carrying a gene to express green or red fluorescence,were injected into the parietal cortex of four rhesus monkeys.The expression of fluorescent cells was used to quantify transfection efficiency.Histological results revealed that recombinant adeno-associated viral vectors,especially the serotype 2/9 coupled with the cytomegalovirus,human synapsin I,or Ca2+/calmodulin-dependentproteinkinaseII promoters,and lentiviral vector coupled with the human ubiquitin C promoter,induced higher expression of fluorescent cells,representing high transfection efficiency.This is the first comparison of transfection efficiencies of different viral vectors carrying different promoters and serotypes in non-human primates(NHPs).These results can be used as an aid to select optimal vectors to transfer exogenous genes into the central nervous system of non-human primates. | Shi-Hao Wu Zhi-Xing Liao Joshua D. Rizak Na Zheng Lin-Heng Zhang Hen Tang Xiao-Bin He Yang Wu Xia-Ping He Mei-Feng Yang Zheng-Hui Li Dong-Dong Qin Xin-Tian Hu | 2017 | Zoological Research2017，38，2： | 7 |
| 2 | Air quality during the 2008 Beijing Olympic Games显示文摘 | David G. Streets Joshua S. Fu Carey J. Jang Jiming Hao Kebin He Xiaoyan Tang Yuanhang Zhang Zifa Wang Zuopan Li Qiang Zhang Litao Wang Binyu Wang Carolyne Yu | 2006 | Atmospheric Environment2006，，3： | 6 |
| 3 | Automated generation and ensemble-learned matching of X-ray absorption spectra显示文摘X-ray absorption spectroscopy(XAS)is a widely used materials characterization technique to determine oxidation states,coordination environment,and other local atomic structure information.Analysis of XAS relies on comparison of measured spectra to reliable reference spectra.However,existing databases of XAS spectra are highly limited both in terms of the number of reference spectra available as well as the breadth of chemistry coverage.In this work,we report the development of XASdb,a large database of computed reference XAS,and an Ensemble-Learned Spectra IdEntification(ELSIE)algorithm for the matching of spectra.XASdb currently hosts more than 800,000 K-edge X-ray absorption near-edge spectra(XANES)for over 40,000 materials from the open-science Materials Project database.We discuss a high-throughput automation framework for FEFF calculations,built on robust,rigorously benchmarked parameters.FEFF is a computer program uses a real-space Green’s function approach to calculate X-ray absorption spectra.We will demonstrate that the ELSIE algorithm,which combines 33 weak“learners”comprising a set of preprocessing steps and a similarity metric,can achieve up to 84.2% accuracy in identifying the correct oxidation state and coordination environment of a test set of 19 K-edge XANES spectra encompassing a diverse range of chemistries and crystal structures.The XASdb with the ELSIE algorithm has been integrated into a web application in the Materials Project,providing an important new public resource for the analysis of XAS to all materials researchers.Finally,the ELSIE algorithm itself has been made available as part of veidt,an open source machine-learning library for materials science. | Chen Zheng Kiran Mathew Chi Chen Yiming Chen Hanmei Tang Alan Dozier Joshua J.Kas Fernando D.Vila John J.Rehr Louis F.J.Piper Kristin A.Persson Shyue Ping Ong | 2018 | npj Computational Materials2018，，1： | 3 |
| 4 | Red cabbage washing with acidic electrolysed water:effects on microbial quality and physicochemical properties显示文摘The effects of acidic electrolysed water(AEW)as‘green’technology on the microbiological and physicochemical properties of fresh-cut red cabbages were studied.Fresh-cut red cabbages and artificially inoculated red cabbages with Salmonella typhimurium DT104 were washed with distilled water(DW)and different available chlorine concentrations(ACC)of AEW for different times.AEW treatments significantly reduced the populations of native aerobic bacteria,molds,and yeasts,and artificially inoculated S.typhimurium DT104 compared with the DW-treated and untreated red cabbage samples.The effectiveness of AEW treatments was greatly enhanced with increasing ACC and treatment times.S.typhimurium DT104 were not detected in the washing water that were collected after the red cabbages treated by AEW.The surface colour,pH,and total phenolic contents did not significantly change when the red cabbages were washed with DW and AEW containing 100 mg/L available chlorine for 3 min.The anthocyanin contents and antioxidant activities of red cabbage were significantly reduced by 18.5 per cent for cyanidin,22.1 per cent for pelargonidin,and 11.2 per cent for 2,2-diphenyl-1-picrylhydrazyl(DPPH)radical scavenging activity,however,the impacts on the nutritional benefits of red cabbage were considered as limited and acceptable.The optimal process condition of AEW for washing red cabbage was 100 mg/L ACC for 3 min.In these conditions,most of the native microflora were inactivated,and artificially inoculated S.typhimurium DT104 on the red cabbage were reduced by 40.2 per cent[3.67 log CFU/g(log10 colony-forming units per gram)]and with minimal losses of nutrients and antioxidant activity,as well as no requirement of decontamination treatment on the washing water after AEW treatment. | Xia Chen Sophia Jun Xue John Shi Magdalena Kostrzynska Joshua Tang Evelyne Guévremont Sébastien Villeneuve Martin Mondor | 2018 | Food Quality and Safety2018，2，4： | 2 |
| 5 | Inorganic/organic hybrid coatings for aircraft aluminum alloy substrates显示文摘 | JOSHUA DUA Y MATT DAMRONA GRACE TANG | 2001 | Progress in Organic Coatings2001，41，： | 1 |
| 6 | Certainty and Discretion in Planning Control: A Case Study of Office Development in Hong Kong显示文摘 | Tang Bo-Sin Lemon H T Choy Joshua K F Wat | 2000 | Urban Studies2000，，13： | 1 |
| 7 | Inorganic/or- ganic hybrid coating for aircraft aluminum alloy zubstrates 显示文摘 | Y Joshua Du Matt Damron Grace Tang | 2001 | Progress in Organic Coatings2001，41，： | 1 |
| 8 | Petri-ne>based coordination algorithms for grid transactions显示文摘 | Tang Fei-long Li Ming-lu Huang Joshua Zhexue | 2005 | Lecture Notes in Computer Science2005，3358，： | 1 |
| 9 | Association of Novel Genetic Loci With Circulating Fibrinogen Levels: A Genome-Wide Association Study in 6 Population-Based Cohorts显示文摘 | Abbas Dehghan Qiong Yang Annette Peters Saonli Basu Joshua C. Bis Alicja R. Rudnicka Maryam Kavousi Ming-Huei Chen Jens Baumert Gordon D.O. Lowe Barbara McKnight Weihong Tang Moniek de Maat Martin G. Larson Susana Eyhermendy Wendy L. McArdle Thomas Lumley | 2009 | Circulation: Cardiovascular Genetics2009，，2： | 1 |
| 10 | Air quality during the 2008 Beijing Olympic Games显示文摘 | David G. Streets Joshua S. Fu Carey J. Jang Jiming Hao Kebin He Xiaoyan Tang Yuanhang Zhang Zifa Wang Zuopan Li Qiang Zhang Litao Wang Binyu Wang Carolyne Yu | 2006 | Atmospheric Environment2006，，3： | 1 |
| 11 | Plasma homocysteine level- sand risk of Alzheimer disease 显示文摘 | Jose AL Ming_ Xin Tang Joshua M | 2004 | Neurology2004，62，11： | 1 |
| 12 | Inorganic/ organic hybrid coatings for aircraft aluminum alloy substrates显示文摘 | Joshua Du Y Matt Damron Grace Tang | 2001 | Progress in Organic Coatings2001，41，4： | 1 |
| 13 | Inorganic/organic hybrid coatings for aircraft aluminum alloy substrates显示文摘 | JOSHUA Du Y DAMRON M TANG G | 2001 | Progress in Organic Coatings2001，，41： | 1 |
| 14 | Relation of plasma homocysteine to plasma amyloid beta leve is 显示文摘 | Jose AL Ming Xin Tang Joshua M | 2007 | Neurochem Res2007，32，45： | 1 |
| 15 | Inorganic/organic hybrid coatings for aircraft aluminum alloy substrates 显示文摘 | JOSHUA DUA Y DAMRONA Matt TANG Grace | 2001 | Progress in Organic Coatings2001，41，： | 1 |
| 16 | Inorganic/Organic Hybrid Coatings for Aircraft Aluminum Alloy Substrates显示文摘 | JOSHUA DU Y DAMRON Matt TANG Grace | 2001 | Progress in Organic Coatings2001，41，4： | 1 |
| 17 | Catalytic reduction of oxygen and hydrogen peroxide by nanoporous gold显示文摘 | Roswitha Zeis Tang Lei Karl Sieradzki Joshua Snyder Jonah Erlebacher | 2007 | Journal of Catalysis2007，，1： | 1 |
| 18 | Historic distribution and recent loss of tigers in China显示文摘Historical records can provide important evidence of changes in distributions of wildlife species.Here we discuss the distribution of the tiger(Panthera tigris Linnaeus,1758)over the past 2000 years in China based on 2635 historical records.We also compare tiger distributions outlined in these records with ecosystem type maps.Throughout this time period,tigers maintained a broad distribution across 7 biomes(from forests to deserts).However,in recent decades the range has been significantly condensed.Today,only 2 populations remain,neither of which is independently viable.Tigers have completely disappeared from the temperate broadleaf and mixed forests of central China,a region that was traditionally their most important biome in China.The continued presence of wild tigers in China is highly dependent on significant conservation measures. | Aili KANG Yan XIE Jirong TANG Eric W.SANDERSON Joshua R.GINSBERG Endi ZHANG | 2010 | Integrative Zoology2010，5，4： | 1 |
| 19 | Effect of dietary supplementation of chitosan and galacto-mannan-oligosaccharide on serum parameters and the insulin-like growth factor-I mRNA expression in early-weaned piglets显示文摘 | Zhi-Ru Tang Yu-Long Yin Charles M. Nyachoti Rui-Lin Huang Tie-Jun Li Chengbo Yang Xiao-jian Yang Joshua Gong Jiang Peng De-Sheng Qi Jian-Jun Xing Zhi-Hong Sun Ming Z. Fan | 2005 | Domestic Animal Endocrinology2005，，4： | 1 |
| 20 | Inorganic/organichybrid coatings for aircraft aluminum alloy substrates显示文摘 | Y Joshua Du M Damron G Tang | 2001 | Prog Org Coat2001，41，： | 1 |
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