|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | An Anatomic Study of the Superficial Peroneal Nerve Accessory Artery Perforator Flaps显示文摘 | Jun Sik Kim Dae Gu Son Tac Hyun Choi | 2008 | Annals of Plastic Surgery2008，5，6： | 1 |
| 2 | Comparison of the efficacy and tolerability of pitavastatin and atorvastatin: An 8-week, multicenter, randomized, open-label, dose-titration study in korean patients with hypercholesterolemia显示文摘 | Sang Hak Lee Namsik Chung Jun Kwan Doo-Il Kim Won Ho Kim Chee Jeong Kim Hyun Seung Kim Si Hoon Park Hong Seog Seo Dong Gu Shin Yung Woo Shin Wan-Joo Shim Tae Hoon Ahn Kyeong Ho Yun Myeong-Ho Yoon Kwang-Soo Cha Si-Wan Choi Seong Wook Han Min Su Hyon | 2007 | Clinical Therapeutics2007，，11： | 1 |
| 3 | High-dose dietary zinc promotes prostate intraepithelial neoplasia in a murine tumor induction mode显示文摘 | Young Hwii Ko Yu Jeong Woo Jin Wook Kim Hoon Choi Seok Ho Kang Jeong Gu Lee Je Jong Kim Hong Seok Park Jun Cheon | 2010 | Asian Journal of Andrology2010，12，2： | 1 |
| 4 | Effects of air temperature and air flow rate control on the tipburn occurrence of leaf lettuce in a closed-type plant factory system 显示文摘 | Jun Gu Lee Chang Sun Choi Yoon Ah Jang Suk Woo Jang Sang Gyu Lee Yeong Cheol Urn | 2013 | Hort Environ Biotechnol2013，54，4： | 1 |
| 5 | An Anatomic Study of the Superficial Peroneal Nerve Accessory Artery Perforator Flaps显示文摘 | Jun Sik Kim Dae Gu Son Tac Hyun Choi | 2008 | An- nals of Plastic Surgery2008，5，6： | 1 |
| 6 | Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1显示文摘The precise regulation of microRNA(miRNA)biogenesis is crucial for plant development,which requires core microprocessors and many fine tuners to coordinate their miRNA processing activity/specificity in fluctuating cellular environments.During de-etiolation,light triggers a dramatic accumulation of core microprocessors and primary miRNAs(pri-miRNAs)but decreases pri-miRNA processing activity,resulting in relatively constant miRNA levels.The mechanisms underlying these seemingly contradictory regulatory changes remain unclear.In this study,we identified forkhead-associated domain 2(FHA2)as a light-stabilized suppressor of miRNA biogenesis.We found that FHA2 deficiency increased the level of mature miRNAs,accompanied by a reduction in pri-miRNAs and target mRNAs.Biochemical assays showed that FHA2 associates with the core microprocessors DCL1,HYL1,and SE,forming a complex to suppress their pri-miRNA processing activity.Further analyses revealed that FHA2 promotes HYL1 binding but inhibits the binding of DCL1-PAZ-RNase-RNA-binding domains(DCL1-PRR)to miRNAs,whereas FHA2 does not directly bind to these RNAs.Interestingly,we found that FHA2 protein is unstable in the dark but stabilized by light during de-etiolation.Consistently,disruption of FH A led to defects in light-triggered changes in miRNA expression and reduced the survival rate of deetiolated seedlings after prolonged light deprivation.Collectively,these data suggest that FHA2 is a novel light-stabilized suppressor of miRNA biogenesis and plays a role in fine-tuning miRNA processing during de-etiolation. | Seung Jun Park Suk Won Choi Gu Min Kim Christian Moller Hyun-Sook Pai Seong Wook Yang | 2021 | Molecular Plant2021，14，4： | 1 |
| 7 | An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korea显示文摘 | Jun Gu Choi Youn Jeong Lee Yong Joo Kim | 2008 | J Vet Sic2008，9，1： | 1 |
| 8 | Follicle-stimulating hormone receptor gene polymorphism and ovarian responses to controlled ovarian hyperstimulation for IVF-ET显示文摘 | Jong Kwan Jun Ji Sung Yoon Seung-Yup Ku Young Min Choi Kyu Ri Hwang Seo Young Park Gyoung Hoon Lee Won Don Lee Seok Hyun Kim Jung Gu Kim Shin Yong Moon | 2006 | Journal of Human Genetics2006，，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员