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| 1 | Conventional endoscopic features are not sufficient to differentiate small, early colorectal cancer显示文摘AIM:To evaluate the depth of invasion of small,early colorectal cancers(ECCs)using conventional endoscopic features.METHODS:From January 2005 to September 2011,colonoscopy cohort showed that a total of 72 patients with small colorectal cancers with the size less than 20mm underwent colonoscopy at the Yonsei University College of Medicine,Seoul,South Korea.Among them,8 patients were excluded due to incomplete medical records.Finally,a total of 64 ECCs with submucosa(SM)invasion and size less than 20 mm were included.One hundred fifty-two adenomas with size less than 20 mm were included as controls.Nine endoscopic features,including seven morphological findings(i.e.,loss of lobulation,excavation,demarcated and depressed areas,stalk swelling,fullness,fold convergence,and bleeding ulcers),pit patterns,and non-lifting signs,were evalu-ated retrospectively.All endoscopic features were evaluated by two experienced endoscopists who have each performed over 1000 colonoscopies annually for more than five years without knowledge of the histology.RESULTS:Among the morphological findings,the size of deep submucosal cancers was bigger than that of superficial lesions(16.9 mm vs 12.3 mm,P<0.001).Also,demarcated depressed areas,stalk swelling,and fullness were more common in deep SM cancers than in superficial tumors(demarcated depressed areas:52.0%vs 15.7%,P<0.001;stalk swelling:100%vs4.2%,P<0.001;fullness:25.0%vs 0%,P=0.001).Among deep SM cancers,96%of polyps showed invasive pit patterns,whereas 19.4%of superficial tumors showed invasive pit patterns(P<0.001).A positive non-lifting sign was more common in deep SM cancers(85.0%vs 28.6%,P<0.001).Diagnostic accuracy of invasive morphology,invasive pit patterns,and nonlifting signs for deep SM cancers were 71%,82%,and75%,respectively.CONCLUSION:Conventional endoscopic findings were insufficient to discriminate small,deep SM cancers from superficial SM cancers by white light,standard colonoscopy. | Wan Park Bun Kim Soo Jung Park Jae Hee Cheon Tae Il Kim Won Ho Kim Sung Pil Hong | 2014 | World Journal of Gastroenterology2014，20，21： | 11 |
| 2 | Effect of gadolinium incorporation on optical characteristics of YNbO_4:Eu^(3+) phosphors for lamp applications显示文摘Eu3+-doped (Y,Gd)NbO4 phosphor was synthesized by solid-state reaction for possible application in cold cathode fluorescent lamps. A broad absorption band with peak maximum at 272 nm was observed which was due to the charge transfer between Eu3+ ions and neighboring oxygen anions. A deep red emission at the peak wavelength of 612 nm was observed which could be attributed to the 5D0→7F2 transition in Eu3+ ions. The highest luminance for Y1-x-yGdyNbO4:Eux3+ under 254 nm excitation was achieved at Eu3+ concentration of 18 mol.% (x=0.18) and Gd3+ concentration of 8.2 mol.% (y=0.082). The luminance of Y0.738Gd0.082NbO4:Eu3+0.18 was higher than that of a typical commercial phosphor Y2O3:Eu3+ and the CIE chromaticity coordinate was (0.6490, 0.3506), which was deeper than that of Y2O3:Eu3+. The particle size of the synthesized phosphors was controlled by the NaCl flux and particle size as high as 8 μm with uniform size distribution of particles was obtained. | Sung Hwan Choi G. Anoop Dong Wook Suh Kyung Pil Kim Hyun Ju Lee Jae Soo Yoo | 2012 | Journal of Rare Earths2012，30，3： | 7 |
| 3 | Correlations between endoscopic and clinical disease activity indices in intestinal Behcet's disease显示文摘AIM:To develop a novel endoscopic severity model of intestinal Behcet's disease(BD) and to evaluate its feasibility by comparing it with the actual disease activity index for intestinal Behcet's disease(DAIBD).METHODS:We reviewed the medical records of 167 intestinal BD patients between March 1986 and April 2011.We also investigated the endoscopic parameters including ulcer locations,distribution,number,depth,shape,size and margin to identify independent factors associated with DAIBD.An endoscopic severity model was developed using significant colonoscopic variables identified by multivariate regression analysis and its correlation with the DAIBD was evaluated.To determine factors related to the discrepancy between endoscopic severity and clinical activity,clinical characteristics and laboratory markers of the patients were analyzed.RESULTS:A multivariate regression analysis revealed that the number of intestinal ulcers(≥ 2,P = 0.031) and volcanoshaped ulcers(P = 0.001) were predictive factors for the DAIBD.An endoscopic severity model(Y) was developed based on selected endoscopic variables as follows:Y = 47.44 + 9.04 × non-Ileocecal area + 11.85 ×≥ 2 of intestinal ulcers + 5.03 × shallow ulcers + 12.76 × deep ulcers + 4.47 × geographicshaped ulcers + 26.93 × volcano-shaped ulcers + 8.65 ×≥ 20 mm of intestinal ulcers.However,endoscopic parameters used in the multivariate analysis explained only 18.9% of the DAIBD variance.Patients with severe DAIBD scores but with moderately predicted disease activity by the endoscopic severity model had more symptoms of irritable bowel syndrome(21.4% vs 4.9%,P = 0.026) and a lower rate of corticosteroid use(50.0% vs 75.6%,P = 0.016) than those with severe DAIBD scores and accurately predicted disease by the model.CONCLUSION:Our study showed that the number of intestinal ulcers and volcano-shaped ulcers were predictive factors for severe DAIBD scores.However,the correlation between endoscopic severity and DAIBD(r = 0.434) was weak. | Hyun Jung Lee Youn Nam Kim Hui Won Jang Han Ho Jeon Eun Suk Jung Soo Jung Park Sung Pil Hong Tae Il Kim Won Ho Kim Chung Mo Nam Jae Hee Cheon | 2012 | World Journal of Gastroenterology2012，18，40： | 5 |
| 4 | The differential impact of microsatellite instability as a marker of prognosis and tumour response between colon cancer and rectal cancer显示文摘 | Sung Pil Hong Byung So Min Tae Il Kim Jae Hee Cheon Nam Kyu Kim Hoguen Kim Won Ho Kim | 2011 | European Journal of Cancer2011，，8： | 3 |
| 5 | Surgically induced astigmatism in combined phacoemulsification and vitrectomy; 23-gauge transconjunctival sutureless vitrectomy versus 20-gauge standard vitrectomy显示文摘 | Dong Ho Park Jae Pil Shin Si Yeol Kim | 2009 | Graefe’s Archive for Clinical and Experimental Ophthalmology2009，，10： | 2 |
| 6 | Long-term outcome of palliative therapy for malignant colorectal obstruction in patients with unresectable metastatic colorectal cancers: endoscopic stenting versus surgery显示文摘 | Hyun Jung Lee Sung Pil Hong Jae Hee Cheon Tae Il Kim Byung So Min Nam Kyu Kim Won Ho Kim | 2011 | Gastrointestinal Endoscopy2011，，3： | 2 |
| 7 | Clinical outcomes and risk factors for technical and clinical failures of self-expandable metal stent insertion for malignant colorectal obstruction显示文摘 | Jin Young Yoon Yoon Suk Jung Sung Pil Hong Tae Il Kim Won Ho Kim Jae Hee Cheon | 2011 | Gastrointestinal Endoscopy2011，，4： | 2 |
| 8 | Negative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding显示文摘 | Jae Jun Park Jae Hee Cheon Hee Man Kim Hyeun Sung Park Chang Mo Moon Jin Ha Lee Sung Pil Hong Tae Il Kim Won Ho Kim | 2010 | Gastrointestinal Endoscopy2010，，6： | 2 |
| 9 | Intestinal Behet's disease appearing during treatment with adalimumab in a patient with ankylosing spondylitis显示文摘Behet’s disease(BD)is a chronic inflammatory disease affecting multiple organ systems,such as the skin,joints,blood vessels,central nervous system,and gastrointestinal tract.Intestinal BD is characterized by intestinal ulcerations and gastrointestinal symptoms.The medical treatment of intestinal BD includes corticosteroids and immunosupressants.There have been several reports of tumor necrosis factor-α (TNF-α)blockers being successful in treatment of refractory intestinal BD.Here,we report on a patient who was diagnosed with intestinal BD despite treatment with the fully humanized TNF-α blocker(adalimumab)for underlying ankylosing spondylitis.This patient achieved clinical remission and complete mucosal healing through the addition of a steroid and azathioprine to the adalimumab regimen. | Sook Hee Chung Soo Jung Park Sung Pil Hong Jae Hee Cheon Tae Il Kim Won Ho Kim | 2013 | World Journal of Gastroenterology2013，19，32： | 2 |
| 10 | Negative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding显示文摘 | Jae Jun Park Jae Hee Cheon Hee Man Kim Hyeun Sung Park Chang Mo Moon Jin Ha Lee Sung Pil Hong Tae Il Kim Won Ho Kim | 2010 | Gastrointestinal Endoscopy2010，，6： | 1 |
| 11 | Effect of ultrasound ondisperse dye particle size 显示文摘 | LEE Keun Wan KIM Jae Pil | 2001 | Textile TechnologyOverseas2001，71，5： | 1 |
| 12 | Surveillance Strategy for Rectal Neuroendocrine Tumors According to Recurrence Risk Stratification显示文摘 | Dong Hyun Kim Jin Ha Lee Yoon Jin Cha Soo Jung Park Jae Hee Cheon Tae Il Kim Hoguen Kim Won Ho Kim Sung Pil Hong | 2014 | Digestive Diseases and Sciences2014，，4： | 1 |
| 13 | Intravitreal injection of bevacizumab and triamcinolone acetonide at the end of vitrectomy for diabetic vitreous hemorrhage: a comparative study显示文摘 | Dong Ho Park Jae Pil Shin Si Yeol Kim | 2010 | Graefe’s Archive for Clinical and Experimental Ophthalmology2010，，5： | 1 |
| 14 | Endoscopic stenting is not as effective for palliation of colorectal obstruction in patients with advanced gastric cancer as emergency surgery显示文摘 | Bo Kyung Kim Sung Pil Hong Hyun Mi Heo Jin Young Kim Hyuk Hur Kang Young Lee Jae Hee Cheon Tae Il Kim Won Ho Kim | 2012 | Gastrointestinal Endoscopy2012，，2： | 1 |
| 15 | Limited subacromial gliding of the supraspinatus tendon during dynamic ultrasonography can predict a decrease in capacity and MR arthrographic features of the shoulder joint显示文摘 | In Kim Jae Hyuck Yi Jongmin Lee Ji Hea Bae Jae-Kwang Lim Jong Pil Yoon In-Ho Jeon | 2012 | European Radiology2012，，11： | 1 |
| 16 | Topical application of Pleurotus eryngii extracts inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by the regulation of Th1/Th2 balance显示文摘 | Jae Ho Choi Hyung Gyun Kim Sun Woo Jin Eun Hee Han Tilak Khanal Minh Truong Do Yong Pil Hwang Jun Min Choi Sung-Sik Chun Young Chul Chung Tae Cheon Jeong Hye Gwang Jeong | 2013 | Food and Chemical Toxicology2013，，： | 1 |
| 17 | Capsular block syndrome after cataract surgery:clinical analysis and classification显示文摘 | Hong Kyum Kim Jae Pil Shin | | 0，，： | 1 |
| 18 | Long‐term incidence, risk factors, and management of biliary complications after adult living donor liver transplantation显示文摘 | Shin Hwang Sung‐Gyu Lee Kyu‐Bo Sung Kwang‐Min Park Ki‐Hun Kim Chul‐Soo Ahn Young‐Joo Lee Sung‐Koo Lee Gyu‐Sam Hwang Deok‐Bog Moon Tae‐Yong Ha Dong‐Sik Kim Jae‐Pil Jung Gi‐Won Song | 2006 | Liver Transpl2006，，5： | 1 |
| 19 | Purple sweet potato anthocyanins attenuate hepatic lipid accumulation through activating adenosine monophosphate–activated protein kinase in human HepG2 cells and obese mice显示文摘 | Yong Pil Hwang Jae Ho Choi Eun Hee Han Hyung Gyun Kim Ji-Hyang Wee Kyung Ok Jung Kyung Hee Jung Kwang-il Kwon Tae Cheon Jeong Young Chul Chung Hye Gwang Jeong | 2011 | Nutrition Research2011，，12： | 1 |
| 20 | Endoscopic stenting is not as effective for palliation of colorectal obstruction in patients with advanced gastric cancer as emergency surgery显示文摘 | Bo Kyung Kim Sung Pil Hong Hyun Mi Heo Jin Young Kim Hyuk Hur Kang Young Lee Jae Hee Cheon Tae Il Kim Won Ho Kim | 2012 | Gastrointestinal Endoscopy2012，，2： | 1 |
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