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| 1 | DESIGN METHODOLOGY OF NETWORKED SOFTWARE EVOLUTION GROWTH BASED ON SOFTWARE PATTERNS显示文摘最近,建筑群的新特征联网的一些在不同领域里吸引科学家的注意,并且导致许多种新兴的研究方向。到目前为止,大多数研究工作被结构分析在大规模软件系统在复杂网络特征的发现限制了。这篇论文论述理论基础,设计方法,算法和研究的实验结果。它第一为网络拓扑学强调进化生长的设计方法的意义面向对象(OO ) 软件系统,并且主张有各种各样的拓扑学特征的网络模型的选择和调整将在设计的进程和 OO 软件系统的实现上带不可忽略的效果。然后,我们与不同拓扑学特征和软件建模方法的发展分析“在网络模型的进化之间的否定和妥协的否定”的类似的纪律。根据软件模式的生长特征的分析,我们连续建议一个面向对象的软件网络进化生长方法和它的算法。另外,我们也基于复杂网络理论为 OO 软件系统度量标准建议参数系统。基于这些参数系统,它能分析各种各样的节点的特征,连接并且本地世界,调制网络拓扑学并且指导软件度量标准。所有这些能对详细设计,实现和表演分析有用。最后,我们集中于进化算法的应用程序并且由案例研究表明它。在实验软件工程从我们的早实验把结果与方法论作比较,我们相信建议软件工程设计方法基于复杂网络理论是一条计算软件工程途径。我们主张这个方法应该是极大地为在大规模 OO 的功能,结构和性能的设计,实现,调整和度量标准有益软件建筑群系统。 | Keqing HE Rong PENG Jing LIU Fei HE Peng LIANG Bing LI | 2006 | Journal of Systems Science & Complexity2006，19，2： | 24 |
| 2 | LA-ICP-MS zircon U-Pb dating and phenocryst EPMA of dikes, Guocheng, Jiaodong Peninsula: Implications for North China Craton lithosphere evolution显示文摘Widespread dike swarm, including diorite-, monzonite-porphyry and lamprophyre, intruded in the al- tered breccia gold deposits along basin marginal faults, Guocheng, Jiaodong Peninsula. Petrography exhibits biotite enclaves in amphibole phenocrysts and the presence of acicular apatites in these dikes. Electron probe microanalyses (EPMA) show that the amphibole and clinopyroxene phenocryst’s mantle in diorite porphyry and lamprophyre respectively has sharply higher MgO (Mg#) and Cr2O3 contents in contrast to their cores. The plagioclase phenocryst in monzonite porphyry has reverse zoning. These results indicate that the magma mixing between mantle-derived mafic and crust-derived felsic magmas occurred in the original process of the dikes. Zircon cathodoluminescence (CL) images show well-developed magmatic oscillatory zones and the acquired LA-ICP-MS zircon U-Pb weighted mean 206Pb/238U ages are 114±2 Ma (MSDW=1.5) for monzonite porphyry (GS1) and 116±1 Ma (MSDW=0.8) for diorite porphyry (GS2), respectively. Earlier magmatic events in the northwest Jiaodong Peninsula represented by some inherited or captured zircons also occur in these dikes. Magmatic zircons from GS1 and GS2 display consistent chondrite-normalized REE patterns and Nb/Ta values, implying that they may share a similar or same source. HREE enrichment and obvious negative Eu anomalies of these zircons preclude garnet presented in their source. Our results, combined with preciously pub- lished data, indicate that dike intrusion and gold mineralization among quartz vein, altered tectonite and altered breccia gold deposits are broadly contemporaneous throughout the Jiaodong Peninsula. These also imply that the intensive crust-mantle interaction and asthenospheric underplating had oc- curred in the Early Cretaceous in the Peninsula, together with foundering of lower crust in the early Mesozoic, representing the different stages of lithosphere thinning in the North China Craton (NNC). | TAN Jun WEI JunHao GUO LingLi ZHANG KeQing YAO ChunLiang LU JianPei LI HongMei | 2008 | Science China Earth Sciences2008，51，10： | 23 |
| 3 | In-situ U-Pb dating of uraninite by fs-LA-ICP-MS显示文摘In this study,the Pb/U fractionation between zircon and uraninite during femtosecond Laser Ablation Inductively Coupled Plasma Mass Spectrometry(fs-LA-ICP-MS)analysis was studied in detail.The results show significant Pb/U fractionation between zircon and uraninite during fs-LA-ICP-MS analysis that when calibrated against the zircon standard M257,the obtained U-Pb age of the Chinese national uraninite standard GBW04420 is 17%older than the recommended value.Thus,the accurate in-situ U-Pb dating of uraninite by LA-ICP-MS requires matrix-matched external standards for calibration.Uraninite in thin sections of two U-mineralized leucogranite from the Gaudeanmus in Namibia was analyzed by a fs-LA-ICP-MS equipped with a Signal Smooth Device(SSD),using laser spot and frequency of 10μm and 1 Hz,respectively.When calibrated using GBW04420 as the external standard,two samples give weighted mean 206Pb/238U ages of 504±3 Ma(2σ,n=21)and503±3 Ma(2σ,n=22),and only one of two samples yields a concordia U-Pb age of 507±1 Ma(2σ,n=21).These results are consistent with ID-TIMS U-Pb ages of 509±1 and 508±12 Ma and are also indistinguishable from zircon U-Pb upper intercept ages of 506±33 Ma(2σ,n=29)and 501±51 Ma(2σ,n=29).The present study shows that in-situ U-Pb dating of uraninite can deliver more reliable formation ages of the deposit than dating coeval high-U zircon because the latter commonly suffer significant Pb loss after formation.Our results confirm that GBW04420 is an ideal matrix matching standard for in-situ U-Pb dating of uraninite. | ZONG KeQing CHEN JinYong HU ZhaoChu LIU YongSheng LI Ming FAN HongHai MENG YanNing | 2015 | Science China Earth Sciences2015，58，10： | 22 |
| 4 | Effects of environmental factors on sulfamethoxazole photodegradation under simulated sunlight irradiation: Kinetics and mechanism显示文摘To advance the knowledge of the environmental fate of sulfamethoxazole(SMX),we systematically investigated the effects of natural water constituents and synthetic substances(i.e.,TiO2 nanoparticles(nTiO2) and Ti-doped β-Bi2O3(NTB)) on the photodegradation kinetics of SMX under xenon lamp irradiation.The photolysis of SMX in aqueous solution followed first-order kinetics.Our results showed that higher concentrations of SMX,fulvic acid,suspended sediments,NTB and higher pH value decreased the photodegradation rates of SMX,whereas H2O2 improved the SMX photodegradation.TiO2 nanoparticles had a dual effect on photodegradation due to their photocatalytic activity and photoabsorption of photons.No intermediates more toxic toward Vibrio fischeri than SMX were produced after direct photolysis and photocatalytic degradation for 3 hr.The photolysis of SMX involved three pathways:hydroxylation,cleavage of the sulfonamide bond,and fragmentation of the isoxazole ring.This study lays the groundwork for a better understanding of the environmental fate of SMX. | Junfeng Niu Lilan Zhang Yang Li Jinbo Zhao Sidan Lv Keqing Xiao | 2013 | Journal of Environmental Sciences2013，25，6： | 14 |
| 5 | Theoretical study on the charge transport properties of triphenylene discogens with a phenylpropionyloxy or 3-phenylpropenoyloxy side chain显示文摘Charge transport is one of the most important properties in organic materials.Charge transport properties of triphenylene discogens with a phenylpropionyloxy or 3-phenylpropenoyloxy side chain have been investigated computationally on the basis of semi-classical Marcus theory.The results show that three triphenylene derivatives have high charge mobility.Title compounds have much better electronic mobility than the triphenylene.The triphenylenes containing 3-phenylpropenoyloxy have better hole mobility,but smaller electronic mobility than the triphenylenes with phenylpropionyloxy.For the triphenylene discogens with a phenylpropionyloxy,the longer the alkloxy chains,the better the positive charge transfer rate,but the smaller the negative charge transfer rate. | CHEN JunRong HUANG ChuRui XU BuYi LI Quan ZHAO KeQing | 2009 | Science China Chemistry2009，52，8： | 7 |
| 6 | An Effective Oxide Interference Correction on Sc and REE for Routine Analyses of Geological Samples by Inductively Coupled Plasma-Mass Spectrometry显示文摘Oxide interference correction plays a vital role in the accurate determination of trace element compositions of geological samples by inductively coupled plasma-mass spectrometry(ICP-MS).In this study,we found that the oxide production is mainly controlled by the gas flow of the ICP-MS and a constant oxide correction factor(OCF)can be measured during a routine analysis.Thus,we can obtain the oxide production by just investigating the gas flow for a fixed ICP-MS system with monitoring of OCF.Si,Ba and LREE oxide interferences on the Sc,Eu and Gd of four geological standard samples GSP-2,JP-1,GBW03112 and GBW03113 were corrected by such method and the results were in good agreement with the recommended values.Therefore,the present study provides a simple and fast correction method for the oxide interferences of the geological samples during the routine analyses.Furthermore,a Microsoft Excel spreadsheet template integrating the correction equations was developed in an in-house software(ICPMSData Cal)for effective calibration. | Wei Zhao Keqing Zong Yongsheng Liu Zhaochu Hu Haihong Chen Ming Li | 2019 | Journal of Earth Science2019，30，6： | 4 |
| 7 | A Doubly Parameterized Detector for Mismatched Signals显示文摘In this paper, we consider the problem of adaptive multichannel signal detection in the presence of signal mismatch, and introduce a novel tunable detector,which is parameterized by two tunable parameters. It has the Constant false alarm rate(CFAR) property and covers Kelly's generalized likelihood ratio test(KGLRT), Adaptive matched filter(AMF), and Adaptive coherence estimator(ACE) as its three special cases. The novel detector controls the mismatched signal by adjusting two tunable parameters. Remarkably, it can achieve improved detection performance for matched signals, enhanced rejection of seriously mismatched signals, and better robustness to slightly mismatched signals than its natural competitors. | LIU Weijian XIE Wenchong ZHANG Qianping LI Rongfeng DUAN Keqing WANG Yongliang | 2015 | Chinese Journal of Electronics2015，24，1： | 3 |
| 8 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 9 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 10 | Serial Interval and Reproductive Number of COVID-19 Among 116 Infector-infectee Pairs—Jingzhou City,Hubei Province,China,2020显示文摘What is already known about this topic?The key epidemiological parameters including serial interval,basic reproductive number(R0),and effective reproductive number(Rt)are crucial for coronavirus disease 2019(COVID-19)control and prevention.Previous studies provided different estimations but were often flawed by some limitations such as insufficient sample size and selection bias.What is added by this report?In this study,a total of 116 infector-infectee pairs meeting strict inclusion criteria were selected for analysis.The mean serial interval of COVID-19 was 5.81 days(standard deviation:3.24).The estimated mean with 95%confidence interval of R0 was 3.39(3.07–3.75)and 2.98(2.62–3.38)using exponential growth(EG)and maximum likelihood(ML)methods,respectively.The Rt in the early phase of the epidemic was above 1 with the peak of 4.43 occurring on January 8,and then showing subsequent declines and approaching 1 on January 24.What are the implications for public health practices?This study supports previous findings that COVID-19 has high transmissibility and that implementing comprehensive measures is effective in controlling the COVID-19 outbreak. | Tian Liu Li Qi Menglei Yao Keqing Tian Maowen Lin Hong Jiang Minmin Zeng Jigui Huang | 2020 | China CDC weekly2020，2，27： | 2 |
| 11 | Meta-modeling of Requirement for Networked Software-An Open Hierarchical & Cooperative Unified Requirement Framework URF 显示文摘 | He Keqing Liang Peng Li Bing | 2007 | DCDIS-B2007，14，6： | 1 |
| 12 | A “wire” signal smoothing device for laser ablation inductively coupled plasma mass spectrometry analysis显示文摘 | Zhaochu Hu Yongsheng Liu Shan Gao Shaoquan Xiao Laishi Zhao Detlef Günther Ming Li Wen Zhang Keqing Zong | 2012 | Spectrochimica Acta Part B: Atomic Spectroscopy2012，，： | 1 |
| 13 | Density functional theory study of hydrogen bonds of bipyridine with 1,3,5- benzenetricarboxylic acid显示文摘 | LI Quan ZHAO Keqing | 2009 | Chinese Journal of Chemistry2009，27，9： | 1 |
| 14 | A transformation definition metamodel for model transformation 显示文摘 | Liu Jin He Keqing Li Bing | 2005 | International Conference on Information Technology: Coding and Computing ITCC2005，2，1： | 1 |
| 15 | Minimum fuel control strategy in automated car-following scenarios 显示文摘 | LI Shengbo PENG Huei LI Keqing | 2012 | VehiTech IEEE Trans2012，61，3： | 1 |
| 16 | Meta modeling of requirement for networked software--An open hierarchical & cooperative unified requirement framework URF 显示文摘 | He Keqing Liang Peng Li Bing | 2007 | Dynamics of Continuous Discrete and Impulsive Systems: Series B Applications and Algorithms2007，14，6： | 1 |
| 17 | Design of beam pumping units based on multi-objective optimal evolutionary algorithm显示文摘 | Ouyang Shan Yu Fahong | 2007 | Natural Computation2007，，： | 1 |
| 18 | Precursor Based on Polyborylborazine for BN Fiber: Preparation and Rheology Properties显示文摘 | Shutong Li Yimiao Cao Keqing Han Xi Zhao Muhuo Yu | 2009 | Journal of Macromolecular Science, Part B2009，，： | 1 |
| 19 | Spectra of Hypergraphs and Applications显示文摘 | Keqing Feng Wen-Ch’ing Winnie Li | 1996 | Journal of Number Theory1996，，60： | 1 |
| 20 | Meta- modeling of Requirement for Networked Software-An Open Hierarchical & Cooperative Unified Requirement Framework URF显示文摘 | He Keqing Liang Peng Li Bing et at | 2007 | Dynamics of Contiunous Discrete and Impulsive Systems (Series B:Applications and Algorithms)2007，14，6： | 1 |
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