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5352篇 您的检索式:作者名="LI G W"
    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function显示文摘在肿瘤和免疫系统之间的相互作用仍然糟糕被理解。重要临床的回答在对 CTLA4 和 PD-1/PD-L1 检查点与抗体对待的癌症病人被完成了;然而,仅仅病人的小部分对治疗作出回应,显示需要探索为癌症治疗的另外的 co 禁止的分子。B7-H3, B7 总科的一个成员,被我们以前显示出禁止 T 房间激活和 autoimmunity。在这研究,我们在肿瘤免疫分析了 B7-H3 的功能。B7-H3 的表示在多重肿瘤线,渗入肿瘤的树枝状的房间,和巨噬细胞被发现。与对抗抗体对待到 B7-H3 的 B7-H3-deficient 老鼠或老鼠显示出多重肿瘤的减少的生长,它取决于 NK 和 CD8 + T 房间。与细胞毒素的淋巴细胞表示的通常认为的受体, B7-H3 禁止了他们的激活,并且它的缺乏在忍受肿瘤的鼠标导致了增加的细胞毒素的淋巴细胞功能。B7-H3 和 PD-1 的联合封锁导致了迟了阶段的肿瘤的进一步提高的治疗学的控制。一起拿,我们的结果显示 B7-H3 检查点可以对癌症为免疫疗法用作一个新奇目标。Young-hee Lee Natalia Martin-Orozco Peilin Zheng Jing Li Peng Zhang Haidong Tan Hyun Jung Park Mira Jeong Seon Hee Chang Byung-Seok Kim Wei Xiong Wenjuan Zang Li Guo Yang Liu Zhong-jun Dong Willem W Overwijk Patrick Hwu Qing Yi Larry Kwak Zhiying Yang Tak W Mak Wei-Li Laszlo G Radvanyi Ling Ni Dongfang Liu Chen Dong 2017Cell Research2017,27,8:29
3Numerical taxonomic study of fast-growing soybean rhizobia and proposal that Rhizobium fredii be assigned to Sinorhizobium gen nov显示文摘CHEN W X YAN G H LI J L 1988Int J Syst Bacteriol1988,38,:3
4A new Early Cretaceous dinosaur track assemblage and the first definite non-avian theropod swim trackway from China显示文摘The trackway of a swimming theropod (ichnogenus Characichnos) is reported from the Lower Cretaceous Feitianshan Formation of Sichuan, China. These swim tracks help confirm that non-avian theropods were capable of forging moderately deep bodies of water. The trackway occurs on the same surface as a typical walking trackway of a sauropod (ichnogenus Brontopodus). Both occurrences are the first reported from the Cretaceous of Sichuan, and the swim tracks are the first well-preserved example of a Characichnos trackway from China. Additionally, a theropod walking trackway and several ornithopod walking trackways (similar to the ichnogenus Caririchnium) occur in the same horizon. The ornithopod trackways show a parallel orientation, suggesting gregarious behavior of the trackmakers, which may have been iguanodontiforms and/or hadrosauriforms. The co-occurrence of theropod swim tracks and theropod walking tracks suggests a fluctuation of water depth within a distinct time span.XING LiDa LOCKLEY Martin G ZHANG JianPing MILNER Andrew R C KLEIN Hendrik LI DaQing PERSONS IV W Scott EBI JieFang 2013Chinese Science Bulletin2013,58,19:3
5Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX 2006中国生物学文摘2006,20,4:2
6鱼、蛋、牛奶、坚果、蔬菜和水果摄入量大,以及低盐膳食模式与高血压的患病率和控制率相关显示文摘食物对高血压患病率和控制率的影响尚不清晰。本文旨在中国人群中调查鱼、蛋、牛奶、坚果、蔬菜和水果摄入量大以及低盐膳食模式是否与高血压有关。方法:从2012年9月到2014年12月共招募15303名受试者进行病例对照研究,分为高血压组(n=1604)和正常血压组(n=13660),其中高血压组又分为血压控制亚组(n=397)和血压未控制亚组(n=1207)。收集过去1 年里每周平均鱼、蛋、牛奶、坚果、蔬菜、水果和盐摄入量数据。鱼、蛋、牛奶、坚果、蔬菜、水果和盐的平均摄入量分别为117、150、35、20、2100、300和58g/周。Yu G Fu H Huang W Zhang N Deng D Li G Lei H 2019中华高血压杂志2019,27,5:2
7A novel functionally graded material in the Ti-Si-C system显示文摘LUO Y G PAN W LI S Q WANG R G LI J Q 2003Mater Sci Eng A2003,345,:1
83-D position sensitive CdZnTe gamma ray spectremeters显示文摘He Z Li W Knoll G F 1999Nucl Instr and Meth in Phys Res1999,422,:1
9Effects of biological soil crusts on emergence of desert vascular plants in North China显示文摘Su Y G Li X R Cheng Y W 2007Plant ecology2007,191,:1
10Residual Stress in Silicon Carbide Particulate Reinforced Aluminum Composites显示文摘SUN Z M LI J B WANG Z G LI W J 1992Acta Metall Mater1992,40,11:1
11Clean double-walled carbon nanotubes synthesized by CVD显示文摘Li W Z Wen J G Sennett M 2003Chem Phys Lett2003,368,:1
12An efficient and convenient procedure for the preparation of 1,1-diacetates from aldehydes catalyzed by H2NSO3H显示文摘Jin T S Sun G Li Y W 2002Green Chem2002,4,:1
13A new triterpenoid from Entodon okamurae Broth 显示文摘ZHANG W LOU H X LI G Y 2003J Asian Nat Prod Res2003,5,3:1
14Direct liquefaction of sawdust under syngas with and without catalyst 显示文摘WANG G LI W LIB Q 2007Chemical Engineering and Processing2007,46,3:1
15Spatial characteristics of Middle Devonian oils and non-associated gases in the Rainbow area, northwest Alberta 显示文摘Chen Z Osadetz Z G Li M W 2005Marine and Petroleum Geology2005,22,3:1
16The completemitochondrial genomes of three cestode species of Taeniainfecting animals and humans 显示文摘Liu G H Lin R Q Li M W 2011Molecular BiologyReport2011,38,4:1
17Subspace Linear Inversion Methods显示文摘Oldenburg D W Li Y G 1994Inverse Problems1994,10,:1
18Well-aligned arrays of CuO nanoplatelets显示文摘Zou G F Li H Zhang D W etaZ 2006J Phys Chem B2006,110,4:1
19Sharp inequalities for periodic functions显示文摘LI J W WANG G Q 2005Applied Mathematics E-Notes2005,,5:1
20New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relation- ship with connexin43显示文摘NICCHIA G P SRINIVAS M LI W 2005FASEB J2005,19,12:1
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