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| 1 | The Yanshanian Granites and Associated Mo-Polymetallic Mineralization in the Xiangcheng-Luoji Area of the Sanjiang-Yangtze Conjunction Zone in Southwest China显示文摘The Xiangcheng-Luoji area is located in the conjunction of the southern part of the 'Sanjiang' mineralization belt and the west margin of Yangtze craton. The geological studies were carried out to know the Indosinian large porphyry Cu polymetallic deposits. Recent studies revealed that the area existed in the superposition of Late Yanshanian acidic intrusive rock belt and developed Mo-Cu polymetallic mineralization where promising exploration results have been achieved. Through the systematic study of geochronology, formation age of the Renlin Mo-minieralization monzogranite is 81.7±1.1 Ma. Re-Os dating results concentrate on 82.34±1.2–88.27±1.23 Ma for the model ages of molbdenite of Tongchanggou Mo deposits, average age is 85 ± 2 Ma where seven data points constitute a good isochron which shows that they were the same period products of mineralization. Geochemical features shown that the rocks have a high content of SiO 2(66.59–77.36wt%), alkaline-rich(K2O=2.68–6.08wt%; Na2O=0.50–4.91wt%; K2O/Na2 O ratios are 0.71–5.56, where average ratio of 1.89) and have aluminum–rich features(Al2O3 10.38–15.15wt%) with σ values less than 3.3. Which indicate that they belong to the high-K calc-alkali to shoshonite series. Geochemistry of Yanshanian intrusions shows that rocks are enrich in LREE with obvious negative δEu anomalies, enrichment of trace elements like, LILE elements(Rb, Th, Ba) with a relative loss of Ba, and loss of high field strength elements(Nb, Ta, P, Ti) and HREE elements. The granite genetic classification diagram shows that the granites belong to A-type granite and formatted in syn-collision tectonic environment. Meanwhile, the Yanshanian granites also inherited the characteristics of island arc environment which formed in the process of crustal melting caused by upwelling of asthenospheric substances in the extensional tectonic background. The process of partial melting existed substances from the deep(lower crust or upper mantle) which have been added. In the Xiangcheng-Luoji area, monzogranite and granodiorite porphyry bodies are widely developed Mo polymetallic mineralization, the deep porphyry mineralization have great potential for geological prospecting. | LI Wenchang YIN Guanghou YU Haijun LIU Xuelong | 2014 | Acta Geologica Sinica(English Edition)2014，88，6： | 20 |
| 2 | Zircon U-Pb Ages of the Granodioritic Porphyry in the Laba Molybdenum Deposit,Yunnan,SW China and Its Geological Implication显示文摘Geza 岛弧是一个著名矿化作用集中区域,在西藏的高原的东方边缘的 Sanjiang 领域的部分。在最近的年里,几迟了的 Yanshanian 花岗石的侵入和联系存款在这个区域被发现了,在桃花源,区域是其一最大 Laba 铝存款。以前的研究建议预定 Laba 矿化作用是 85 ±2 妈。然而, granodioritic 斑岩的年龄仍然保持未知。在这研究,从忍受辉钼矿的 granodioritic 斑岩的三件样品锆石标明日期的 LA-ICP-MS U-Pb 与 85.00 ± 的产生日期一起被进行了0.23 妈(MSWD = 0.58 ) , 85.28 ±0.28 妈(MSWD = 1.12 ) ,并且 84.83 ±0.26 妈(MSWD = 0.79 ) 分别地,显示这些 granodioritic 斑岩在 ∼85 附近在迟了的 Yanshanian 形成了妈。与矿化作用的地质的特征结合了,时间地, Laba 存款遗传上空间地与 granodioritic 斑岩被联系。另外, Laba 存款的年龄与另外的迟了的 Yanshanian 侵入和矿化作用一致,建议矿化作用可能在在迟了的白垩纪期间的 intra 板 extensional 环境下面被产生。 | YU Haijun LI Wenchang YIN Guanghou LU Yingxiang CAO Xiaomin HUANG Dingzhu DONG Tao ZHANG Youming | 2014 | Acta Geologica Sinica(English Edition)2014，88，4： | 14 |
| 3 | Methane emissions from natural and drained peatlands in the Zoigê, eastern Qinghai-Tibet Plateau显示文摘Peatlands are one of the major natural sources of methane(CH_4), but the level of CH_4 efflux is uncertain,especially in alpine peatlands. In this study, CH_4 emission fluxes from natural and drained peatlands on the QinghaiTibet Plateau, southwest China, were measured from June to October in 2013 using the opaque static chamber technique and the Fast Greenhouse Gas Analyzer(DLT-100,Los Gatos Research Corp.). CH_4 emission fluxes ranged from 2.07 to 56.33 mg m^(-2)h^(-1)in natural peatlands and from 0.02 to 0.42 mg m^(-2)h^(-1)in drained peatlands. Mean CH_4 emission flux was 19.13 mg m^(-2)h^(-1)in natural peatlands and 0.14 mg m^(-2)h^(-1)in drained peatlands.These results showed that drainage led to a significant decrease in CH_4 emissions. CH_4 emission fluxes for all sampling plots were significantly correlated with variation in water table depth for linear(R^2= 0.453, P \ 0.01) and exponential functions(R^2= 0.429, P \ 0.01). | Wenchang Zhou Lijuan Cui Yifei Wang Wei Li | 2017 | Journal of Forestry Research2017，28，3： | 6 |
| 4 | Minimum geometric power distortionless response beamforming against heavy-tailed noise of unknown statistics显示文摘A minimum geometric power distortionless response beamforming approach against impulsive noise(including all αstable noise) of unknown statistics is proposed.Due to that definite logarithmic moments require no priori knowledge of impulsive noise,this new beamformer substitutes the logarithmic moments for the second-order moments and iteratively minimizes the 'geometric power' of the beamformer's output snapshots,subjected to a linear constraint.Therefore,the proposed beamformer can provide significantly higher output geometric signal-to-noise-andinterference ratio.Moreover,the optimum weight vector is obtained by using a new iteration process.The simulation results prove that the new method is effective. | Wenchang Wang Lei Li Chunjing Liu Feng Liu | 2011 | Journal of Systems Engineering and Electronics2011，22，5： | 3 |
| 5 | CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance显示文摘 | Gaopeng Li Xiaoli Wu Wenchang Qian Huayong Cai Xinbao Sun Weijie Zhang Sheng Tan Zhengsheng Wu Pengxu Qian Keshuo Ding Xuefei Lu Xiao Zhang Hong Yan Haifeng Song Shouhong Guang Qingfa Wu Peter E Lobie Ge Shan Tao Zhu | 2016 | Cell Research2016，26，6： | 3 |
| 6 | The Late Cretaceous Crustal Magmatism of the Geza Arc Metallogenic Belt in Yunnan Province,and Zircon Ages and Hf Isotopic Evidence of the Porphyry Cu-Mo Mineralization显示文摘Objective The Geza arc in Yunnan Province,located in the southern Yidun arc,is an important part of the Sanjiang tectonic-magmatic belts in southwestern China and is a newly discovered copper polymetallic ore-concentrating district.Recent studies show that the newly discovered Yanshanian porphyry Cu-Mo polymetallic mineralization superimposed in the Indosinian porphyry copper belt | YANG Fucheng LI Wenchang LIU Xuelong WANG Shuaishuai | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 2 |
| 7 | A novel stochastic reaction-diffusion model of Ca^2+ blink in cardiac myocytes显示文摘In cardiac myocytes,the sarcoplasmic reticulum(SR)is the main storage organelle of free Ca^(2+).The concentration of free Ca^(2+)in the SR is 0.5–1.0 mmol/L and is 2–3 orders of magnitude greater than that in the cytosol.The SR is composed of interconnected cisternae(junctional SR,i.e.,JSR)and tubules(free SR network,i.e.,FSR)that extend throughout the cytosol[1].Ca^(2+)is released from the JSR into the cytosol via Ca^(2+)release units(CRUs, | Jinghui Li Wenjun Xie Xi Chen Yunlong Huo Heping Cheng Wenchang Tan | 2017 | Science Bulletin2017，62，1： | 2 |
| 8 | Morphological,Molecular and Pathogenicity of Alternaria gaisen Associated with Leaf Brown-Spot on‘Gonggan’Mandarin in China显示文摘[Objective]This paper was to identify the pathogen of leaf brown-spot on‘gonggan’mandarin(Citrus reticulate var.gonggan)in Zhaoqing,Guangdong Province.[Method]The pathogen was determined based on sequence analysis of ITS,endoPG,tef1,gapdh,Alt a1,rpb2 and opa10-2 genes;the morphological characteristics were recorded on PDA and PCA;and its pathogenicity on excised and intact host leaves of citrus‘gonggan’was tested.[Result]A detailed description of Alternaria gaisen was obtained based on morphological,molecular and pathogenic characterization,which was the causal agent of brown-spot disease on leaves of‘gonggan’mandarin orchard trees in Zhaoqing,Guangdong,China.[Conclusion]This study provides a scientific basis for the effective control of leaf brown-spot on‘gonggan’mandarin. | Cui Mengjiao Sein Lai Lai Aung Wei Xin Yu Zhihe Mo Yanwei Yu Wenchang Deng Jianxin Li Qili | 2020 | Plant Diseases and Pests2020，11，5： | 2 |
| 9 | Combined feed- back method for designing a free-form optical system with complicated illumination patterns for an extended LED source 显示文摘 | Situ Wenchang Han Yanjun Li Hongtao | 2011 | Optics Express2011，19，5： | 1 |
| 10 | Comparative study of big data of global adakites and mineralization-related granite in the Geza arc metallogenic belt, northwest Yunnan, Southwest China显示文摘The Geza arc is an important part of the Sanjiang tectono-magmatic belt and is a newly discovered copper polymetallic ore concentration area in northwest Yunnan province,Southwest China.The area comprises numerous metal ore deposits,including one super-largedeposit,three large deposits,etc.The formation of these deposits was closely related to intermediate–acidic magmatic intrusions.Based on previous studies,the“big data”analysis technique was used for a comparative study of large geochemical datasets of granite related to ore-formation in the Geza porphyry copper deposit and global adakites.As a result,1313 element combinations and 127,765 overlap ratios were obtained.The results show that the Geza porphyry has similar geochemical characteristics to global adakites(the ratios of REE and Ga to major elements are in the range of global adakites).However,theCu,Mo,and Zn contents of the porphyry are significantly higher than those of global adakites,and the porphyry may,therefore,represent an end-member of the global range of adakite composition.In addition,the geochemistry of adakites associated with the porphyry copper deposits overlaps in part with that of global adakites,although most of the data lie outside of the range of global adakites(i.e.lowMn/Cu,Sr/Cu,Na/Cu,and Zr/Cu values,and high Th/Cu,Ba/Cu,Na/Mo,Rb/Mo,Th/Mo,Ta/Mo,Ba/Mo,Mn/Zn,and Ba/Znvalues).The samples with characteristics that deviate significantly from the geochemistry of global adakites show more advanced mineralization and alteration,and a stronger relationship with Cu and Momineralization.The results of geochemical data mining can be used as a prospecting indicator,and provide a new scientific basis for geological prospecting of the deep levels and per-iphery of the Geza Cu polymetallic ore belt. | Liu Xuelong Li Wenchang Zhang Qi Zhang Na Zhang Changzhen Luo Ying Wang Shuaishuai Yang Fucheng Chen Jianhang Li Zhenhuan | 2018 | Big Earth Data2018，2，3： | 1 |
| 11 | Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: Analysis of sentinel physician surveillance data显示文摘 | Fan‐ChenTseng Han‐ChinHuang Chia‐YuChi Tsuey‐LiLin Ching‐ChuanLiu Jhih‐WeiJian Li‐ChingHsu Ho‐ShengWu Jyh‐YuanYang Ya‐WenChang Hsuan‐ChenWang Yun‐WeiHsu Ih‐JenSu Jen‐RenWang | 2007 | J Med Virol2007，，12： | 1 |
| 12 | Post-ore Modification and Preservation of the Indosinian Porphyry Copper Deposit in Geza Arc, Yunnan, SW China显示文摘Objective The post-ore modification and preservation of porphyry copper deposits is controlled and influenced by various geological processes,and the regional uplift and denudation is the most important factors.This study | LIU Xuelong LI Wenchang ZHANG Na LAI Anqi LI Zhe | 2016 | Acta Geologica Sinica(English Edition)2016，90，2： | 1 |
| 13 | Intronic microRNAs: discovery and biological implications 显示文摘 | Li Sungchou Tang Petrus Lin Wenchang | 2007 | DNA Cell Biol2007，26，4： | 1 |
| 14 | Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: Analysis of sentinel physician surveillance data显示文摘 | Fan‐ChenTseng Han‐ChinHuang Chia‐YuChi Tsuey‐LiLin Ching‐ChuanLiu Jhih‐WeiJian Li‐ChingHsu Ho‐ShengWu Jyh‐YuanYang Ya‐WenChang Hsuan‐ChenWang Yun‐WeiHsu Ih‐JenSu Jen‐RenWang | 2007 | J Med Virol2007，，12： | 1 |
| 15 | HMGB1, a potent proinflammatory cytokine in sepsis显示文摘 | Wenchang Huang Yaoqing Tang Lei Li | 2010 | Cytokine2010，，2： | 1 |
| 16 | Ab initio investigation of the cyclodehydrogenation process for polyanthrylene transformation to graphene nanoribbons显示文摘Graphene nanoribbons(GNRs)can be synthesized from molecular precursors with atomic precision.A prominent case is the 7-atom-wide armchair GNR made from 10,10′-dibromo-9,9′-bianthryl(DBBA)precursors on metal substrates through dehalogenation/polymerization followed by cyclodehydrogenation.We investigate the key aspects of the cyclodehydrogenation process by evaluating the energy profiles of various reaction pathways using density functional theory and the nudged elastic band method.The metal substrate plays a critical catalytic role by providing stronger adsorption for products and facilitating H desorption.For polyanthrylene on an extra layer of GNR on Au,the underlying GNR insulates it from the Au substrate and increases the reaction barriers,rendering the polyanthrylene“quasi-freestanding”.However,positive charge injection can induce localized cyclodehydrogenation.We find that this is due to the stabilization of an intermediate state through an arenium ion mechanism and favorable orbital symmetries.These results provide mechanistic insight into the effects of the metal substrate and charge injection on cyclodehydrogenation during GNR synthesis and offer guidance for the design and growth of new graphitic structures. | Zhongcan Xiao Chuanxu Ma Wenchang Lu Jingsong Huang Liangbo Liang Kunlun Hong An-Ping Li Bobby G.Sumpter Jerzy Bernholc | 2019 | npj Computational Materials2019，，1： | 0 |
| 17 | Intra-and inter-specific scaling laws of plants and animals显示文摘The allometric scaling laws of metabolism in 447 animal and 1200 plant species showed convex and concave curvatures between mass and metabolic rate,respectively.The objective of the study is to explain the difference of curvatures between animals and plants based on fractal models.Several intraspecific scaling laws were derived from an asymmetric vascular tree with the fractal dimension(i.e.,a in k^(a)_(1)+k^(a)_(2)+…-=1,where k_(i)refers to the ratio of daughter to mother diameters).Based on the intraspecific scaling laws,the allometric scaling exponent of metabolism(i.e.,an interspecific scaling law)was shown to be equal to one-third of fractal dimension.Moreover,a novel piecewise-defined function in conjunction with the intraspecific scaling laws was proposed to explain the diverse metabolic scaling in animals and plants.The intraspecific and interspecific scaling laws showed good agreement with morphometric measurements.The experimentally-validated scaling models predict the diversity of intraspecific and interspecific scaling seen in nature.To our knowledge,this is the first study to use fractal models to explain the convex and concave forms of metabolic scaling in animals and plants.The study resolves the long-term controversies to use the resource-transport network models for explanation of the allometric scaling law of metabolism. | Jiahang Li Hao Wu Ghassan S。Kassab Wenchang Tan Yunlong Huo | 2021 | Acta Mechanica Sinica2021，37，2： | 0 |
| 18 | Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response显示文摘Inflammatory bowel disease(IBD)is a chronic relapsing gastrointestinal disorder,while the treatment effect is not satisfactory.Immune responsive gene 1(IRG1)is a highly ex-pressed gene in macrophage in response to inflammatory response and catalyzes the production of itaconate.Studies have reported that IRG1/itaconate has a significant antioxidant effect.This study aimed to investigate the effect and mechanism of IRG1/itaconate on dextran sulfate so-dium(DSS)-induced colitis in vivo and in vitro.In vivo experiments,we found IRG1/itaconate ex-erted protective effects against acute colitis by increasing mice weight,the length of colon,reducing disease activity index and colonic inflammation.Meanwhile,IRG1 deletion aggravated the macrophages/CD4+/CD8+T-cell accumulation,and increased the release of interleukin(IL)-1b,tumor necrosis factor-a(TNF-a),IL-6,the activation of nuclear factor-kB(NF-kB)/mitogen-activated protein kinase(MAPK)signaling pathway,and gasdermin D(GSDMD)mediated pyrop-tosis.Four-octyl itaconate(4-OI),a derivative of itaconate,attenuated these changes,therefore relieved DSS-induced colitis.In vitro experiment,we found 4-OI inhibited the reactive oxygen species production,thereby inhibiting the activation of MAPK/NF-kB signaling pathway in RAW264.7 and murine bone-marrow-derived macrophages.Simultaneously,we found 4-OI inhib-ited caspase1/GSDMD-mediated pyroptosis to reduce the release of cytokines.Finally,we found anti-TNF-a agent reduced the severity of DSS-induced colitis and inhibited gasdermin E(GSDME)-mediated pyroptosis in vivo.Meanwhile,our study revealed that 4-OI inhibited caspase3/GSDME-mediated pyroptosis induced by TNF-a in vitro.Taken together,IRG1/itaconate exerted a pro-tective role in DSS-induced colitis by inhibiting inflammatory response and GSDMD/GSDME-medi-ated pyroptosis,which could be a promising candidate for IBD therapy. | Wenchang Yang Yaxin Wang Tao Wang Chengguo Li Liang Shi Peng Zhang Yuping Yin Kaixiong Tao Ruidong Li | 2023 | Genes & Diseases2023，10，4： | 0 |
| 19 | PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis显示文摘Glaucoma is the leading cause of irreversible blindness worldwide.In the pathogen-esis of glaucoma,activated microglia can lead to retinal ganglion cells(RGCs)apoptosis and death,however,the molecular mechanisms remain largely unknown.We demonstrate that phospholipid scramblase 1(PLSCR1)is a key regulator promoting RGCs apoptosis and their clearance by microglia.As evidenced in retinal progenitor cells and RGCs of the acute ocular hypertension(AOH)mouse model,overexpressed PLSCR1 induced its translocation from the nucleus to the cytoplasm and cytomembrane,as well as elevated phosphatidylserine exposure and reactive oxygen species generation with subsequent RGCs apoptosis and death.These damages were effectively attenuated by PLSCR1 inhibition.In the AOH model,PLSCR1 led to an increase in M1 type microglia activation and retinal neuroinflammation.Upregulation of PLSCR1 resulted in strongly elevated phagocytosis of apoptotic RGCs by activated microglia.Taken together,our study provides important insights linking activated microglia to RGCs death in the glaucoma pathogenesis and other RGC-related neurodegenerative diseases. | Jingyi Luo Qing Lian Deliang Zhu Minglei Zhao Tingfang Mei Bizhi Shang Zeqiu Yang Chujun Liu Wenchang Xu Lan Zhou Keling Wu Xinqi Liu Yuhua Lai Fuxiang Mao Weihua Li Chengguo Zuo Kang Zhang Mingkai Lin Yehong Zhuo Yizhi Liu Lin Lu Ling Zhao | 2023 | Genes & Diseases2023，10，4： | 0 |
| 20 | Applications of multiresolution analysis in Besov-Q type spaces and Triebel-Lizorkin-Q type spaces显示文摘In this survey,we give a neat summary of the applications of the multi-resolution analysis to the studies of Besov-Q type spaces B_(p,q)^(γ1,γ2) (R^(n))and Triebel-Lizorkin-Q type spaces B_(p,q)^(γ1,γ2) (R^(n)).We will state briefly the recent progress on the wavelet characterizations,the boundedness of Calderon-Zygmund operators,the boundary value problem of B_(p,q)^(γ1,γ2) (R^(n)) and F_(p,q)^(γ1,γ2) (R^(n)).We also present the recent developments on the well-posedness of fluid equations with small data in B_(p,q)^(γ1,γ2) (R^(n))and F_(p,q)^(γ1,γ2) (R^(n)). | Pengtao LI Wenchang SUN | 2022 | Frontiers of Mathematics in China2022，17，3： | 0 |
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