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| 1 | Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair显示文摘间充质的干细胞(MSC ) 为治疗各种各样的疾病有大潜力,特别那些与织物有关损坏包含有免疫力的反应。各种各样的研究证明了 MSC 在 vitro 并且在 vivo 是强烈抑制免疫力的。我们的最近的研究证明了那未刺激的 MSC 确实不能免疫力的抑制;他们与 TNF- 伪, IL-1 伪或 IL-1 尾与激活的淋巴细胞的上层清液,或与 IFN- 纬的联合在刺激之上变得 potently 抑制免疫力。这观察表明在某些情形下面,煽动性的 cytokines 能实际上变得抑制免疫力。我们证明在调停 MSC 的免疫力的抑制的机制有一个种类变化:由告知 cytokine 的老鼠 MSC 的免疫力的抑制被氮的氧化物调停(没有) 而由告知 cytokine 的人的 MSC 的免疫力的抑制通过 indoleamine 被执行 2, 3-dioxygenase (伊多语) 。在有煽动性的 cytokines 的刺激之上,另外,老鼠和人的 MSC 分泌几白血球 chemokines 显然服务与 MSC 吸引有免疫力的房间进最近,在哪儿不或伊多语被预言很活跃。因此,由煽动性的刺激 cytokine 的 MSC 的免疫力的抑制经由 chemokines 的一致行动发生并且免疫者禁止没有或伊多语由 MSC 生产了。因此,我们的结果在对待有免疫力的回答导致的织物损害关于调停 MSC 的免疫力的抑制并且为 MSC 的更好的申请的机制提供新奇信息。 | Yufang Shi Gangzheng Hu Juanjuan Su Wenzhao Li Qing Chen Peishun Shou Chunliang Xu Xiaodong Chen Yin Huang Zhexin Zhu Xin Huang Xiaoyan Han Ningxia Xie Guangwen Ren | 2010 | Cell Research2010，20，5： | 72 |
| 2 | The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals显示文摘Metabolic diseases are the most common and rapidly growing health issues worldwide.The massive population-based human genetics is crucial for the precise prevention and intervention of metabolic disorders.The China Metabolic Analytics Project(ChinaMAP)is based on cohort studies across diverse regions and ethnic groups with metabolic phenotypic data in China.Here,we describe the centralized analysis of the deep whole genome sequencing data and the genetic bases of metabolic traits in 10,588 individuals from the ChinaMAP.The frequency spectrum of variants,population structure,pathogenic variants and novel genomic characteristics were analyzed.The individual genetic evaluations of Mendelian diseases,nutrition and drug metabolism,and traits of blood glucose and BMI were integrated.Our study establishes a large-scale and deep resource for the genetics of East Asians and provides opportunities for novel genetic discoveries of metabolic characteristics and disorders. | Yanan Cao Lin Li Min Xu Zhimin Feng Xiaohui Sun Jieli Lu Yu Xu Peina Du Tiange Wang Ruying Hu Zhen Ye Lixin Shi Xulei Tang Li Yan Zhengnan Gao Gang Chen Yinfei Zhang Lulu Chen Guang Ning Yufang Bi Weiqing Wang The ChinaMAP Consortium | 2020 | Cell Research2020，30，9： | 20 |
| 3 | The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation显示文摘Interleukin(IL)17-producing T helper(Th17)cells play critical roles in the clearance of extracellular bacteria and fungi as well as the pathogenesis of various autoimmune diseases,such as multiple sclerosis,psoriasis,and ulcerative colitis.Although a global transcriptional regulatory network of Th17 cell differentiation has been mapped recently,the participation of epigenetic modifications in the differentiation process has yet to be elucidated.We demonstrated here that histone H3 lysine-27(H3K27)demethylation,predominantly mediated by the H3K27 demethylase Jmjd3,crucially regulated Th17 cell differentiation.Activation of naı¨ve CD41 T cells immediately induced high expression of Jmjd3.Genetic depletion of Jmjd3 in CD41 T cells specifically impaired Th17 cell differentiation both in vitro and in vivo.Ectopic expression of Jmjd3 largely rescued the impaired differentiation of Th17 cells in vitro in Jmjd3-deficientCD41 T cells.Importantly,Jmjd3-deficient mice were resistant to the induction of experimental autoimmune encephalomyelitis(EAE).Furthermore,inhibition of the H3K27 demethylase activity with the specific inhibitor GSK-J4 dramatically suppressed Th17 cell differentiation in vitro.At the molecular level,Jmjd3 directly bound to and reduced the level of H3K27 trimethylation(me3)at the genomic sites ofRorc,which encodes the masterTh17 transcription factorRorgt,and Th17 cytokine genes such as Il17,Il17f,and Il22.Therefore,our studies established acritical role of Jmjd3-mediatedH3K27demethylation inTh17 cell differentiation andsuggest that Jmjd3 can be a novel therapeutic target for suppressing autoimmune responses. | Zhi Liu Wei Cao Longxia Xu Xi Chen Yu Zhan Qian Yang Sanhong Liu Pengfei Chen Yuhang Jiang Xiaohua Sun Yu Tao Yiming Hu Cuifeng Li Qi Wang Ying Wang Charlie Degui Chen Yufang Shi Xiaoren Zhang | 2015 | Journal of Molecular Cell Biology2015，7，6： | 6 |
| 4 | Investigating long-term vehicle speed prediction based on GA-BP algorithms and the road-traffic environment显示文摘Dear editor,Effective and accurate long-term speed prediction is crucial for intelligent transportation and automobile intelligent energy management systems of intelligent connected vehicles.These predictions have important research value and broad application prospects including widespread use in improving traffic efficiency and safety,fuel economy,remaining driving range estimation[1]. | Yufang LI Chen REN Hongwei ZHAO Guoping CHEN | 2020 | Science China(Information Sciences)2020，63，9： | 6 |
| 5 | Research on optimized GA-SVM vehicle speed prediction model based on driver-vehicle-road-traffic system显示文摘The accurate prediction of vehicle speed plays an important role in vehicle's real-time energy management and online optimization control. However, the current forecast methods are mostly based on traffic conditions to predict the speed, while ignoring the impact of the driver-vehicle-road system on the actual speed profile. In this paper, the correlation of velocity and its effect factors under various driving conditions were firstly analyzed based on driver-vehicle-road-traffic data records for a more accurate prediction model. With the modeling time and prediction time considered separately, the effectiveness and accuracy of several typical artificial-intelligence speed prediction algorithms were analyzed. The results show that the combination of niche immunegenetic algorithm-support vector machine(NIGA-SVM) prediction algorithm on the city roads with genetic algorithmsupport vector machine(GA-SVM) prediction algorithm on the suburb roads and on the freeway can sharply improve the accuracy and timeliness of vehicle speed forecasting. Afterwards, the optimized GA-SVM vehicle speed prediction model was established in accordance with the optimized GA-SVM prediction algorithm at different times. And the test results verified its validity and rationality of the prediction algorithm. | LI YuFang CHEN MingNuo LU XiaoDing ZHAO WanZhong | 2018 | Science China(Technological Sciences)2018，61，5： | 5 |
| 6 | Emerging predictors of the response to the blockade of immune checkpoints in cancer therapy显示文摘Checkpoint blockade-based immunotherapy offers new options and powerful weapons for the treatment of cancer,but its efficacy varies greatly among different types of cancer and across individual patients.Thus,the development of the right tools that can be used to identify patients who could benefit from this therapy is of utmost importance in order to maximize the therapeutic benefit,minimize risk of toxicities,and guide combination approaches.Multiple predictors have emerged that are based on checkpoint receptor ligand expression,tumor mutational burden,neoantigen and microsatellite instability,tumor-infiltrating immune cells,and peripheral blood biomarkers.In this review,we discuss the current state and progress of predictors as aids in checkpoint blockadebased immunotherapy in cancer. | Xiaolei Li Wenhui Song Changshun Shao Yufang Shi Weidong Han | 2019 | Cellular & Molecular Immunology2019，16，1： | 5 |
| 7 | AntarcticaLC2000:The new Antarctic land cover database for the year 2000显示文摘Antarctica plays a key role in global energy balance and sea level change.It has been conventionally viewed as a whole ice body with high albedo in General Circulation Models or Regional Climate Models and the differences of land cover has usually been overlooked.Land cover in Antarctica is one of the most important drivers of changes in the Earth system.Detailed land cover information over the Antarctic region is necessary as spatial resolution improves in land process models.However,there is a lack of complete Antarctic land cover dataset derived from a consistent data source.To fill this data gap,we have produced a database named Antarctic Land Cover Database for the Year 2000(AntarcticaLC2000) using Landsat Enhanced Thematic Mapper Plus(ETM+) data acquired around 2000 and Moderate Resolution Imaging Spectrometer(MODIS) images acquired in the austral summer of 2003/2004 according to the criteria for the 1:100000-scale.Three land cover types were included in this map,separately,ice-free rocks,blue ice,and snow/firn.This classification legend was determined based on a review of the land cover systems in Antarctica(LCCSA) and an analysis of different land surface types and the potential of satellite data.Image classification was conducted through a combined usage of computer-aided and manual interpretation methods.A total of 4067 validation sample units were collected through visual interpretation in a stratified random sampling manner.An overall accuracy of 92.3%and the Kappa coefficient of 0.836 were achieved.Results show that the areas and percentages of ice-free rocks,blue ice,and snow/firn are 73268.81 km2(0.537%),225937.26 km2(1.656%),and 13345460.41 km2(97.807%),respectively.The comparisons with other different data proved a higher accuracy of our product and a more advantageous data quality.These indicate that AntarcticaLC2000,the new land cover dataset for Antarctica entirely derived from satellite data,is a reliable product for a broad spectrum of applications. | HUI FengMing KANG Jing LIU Yan CHENG Xiao GONG Peng WANG Fang LI Zhan YE YuFang GUO ZiQi | 2017 | Science China Earth Sciences2017，60，4： | 5 |
| 8 | An improved Landsat Image Mosaic of Antarctica显示文摘A revised Landsat Image Mosaic of Antarctica (LIMA) is presented, using the 1073 multi-band scenes of the original Landsat-7 ETM+ LIMA image collection available at the United States Geological Survey (USGS: http://gffzza64998f73d704ee0hucpcv9k6qxx06x9p.ffgz.tsg.suse.edu.cn/). Three improvements have been applied during the data processing: (1) DN saturation is adjusted by adopting a linear regression, which has a lower root mean square error than the ratio regression used by LIMA; (2) solar elevation angle is calculated using pixel-level latitude/longitude and the acquisition time and date of the central pixel of the scene, improving slightly upon the bilinear interpolation of the solar elevation angles of scene corners applied in LIMA; and (3) two additional image bands, Band 5 and Band 7, are sharpened using the panchromatic band (Band 8) and a Gram-Schmidt Spectral Sharpening algorithm to more easily distinguish snow, cloud and exposed rocks. The final planetary reflectance product is stored in 16-bit bands to preserve the full radiometric content of the scenes. A comparative statistical analysis among 12 sample regions indicates that the new mosaic has enhanced visual qualities, information entropy, and information content for land cover classification relative to LIMA. | HUI FengMing CHENG Xiao LIU Yan ZHANG YanMei YE YuFang WANG XianWei LI Zhan WANG Kun ZHAN ZhiFei GUO JianHong HUANG HuaBing LI XiuHong GUO ZiQi GONG Peng | 2013 | Science China Earth Sciences2013，56，1： | 4 |
| 9 | 改进的南极洲陆地卫星影像镶嵌图显示文摘研究改进LIMA数据处理方法,使用1073景Landsat7-ETM+数据制作了改进的南极洲陆地卫星影像镶嵌图.改进的镶嵌图较LIMA的优势体现在影像处理流程的3个方面:(1)DN值饱和溢出调整采用更高精度的线性回归方法;(2)利用每个像元的经纬度和影像中心点的拍摄时间逐像元计算太阳高度角,提高了太阳高度角的计算精度;(3)选择了更有效的GS融合方法,将更多的波段(波段5和7)加入融合产品的制作,在南极地类识别上优势更加明显.另外,以16bit进行存储的行星反射率产品很好的保持了冰雪表面的高辐射分辨率.从目视效果、信息熵以及分类等方面与LIMA数据进行比较,结果表明本文数据具有明显的优势. | 惠凤鸣 程晓 刘岩 张艳梅 YuFang YE 王显威 Zhan LI 王坤 詹志飞 虢建宏 黄华兵 李秀红 郭子祺 宫鹏 | 2013 | 中国科学:地球科学2013，43，1： | 3 |
| 10 | HY5 regulates light-responsive transcription of microRNA163 to promote primary root elongation in Arabidopsis seedlings显示文摘MicroRNAs(miRNAs)play key roles in the post-transcriptional regulation of gene expression in plants.Many miRNAs are responsive to environmental signals.Light is the first environmental signal perceived by plants after emergence from the soil.However,less is known about the roles and regulatory mechanism of miRNAs in response to light signal.Here,using small RNA sequencing,we determined that miR163 is significantly rapidly induced by light signaling in Arabidopsis thaliana seedlings.The light-inducible response of miR163 functions genetically downstream of LONG HYPOCOTYL 5(HY5),a central positive regulator of photomorphogenesis.HY5 directly binds to the two G/C-hybrid elements in the miR163 promoter with unequal affinity;one of these elements,which is located next to the transcription start site,plays a major role in light-induced expression of miR163.Overexpression of miR163 rescued the defective primary root elongation of hy5 seedlings without affecting lateral root growth,whereas overexpressing of miR163 target PXMT1 inhibited primary root elongation.These findings provide insight into understanding the post-transcriptional regulation of root photomorphogenesis mediated by the HY5-miR163-PXMT1 network. | Tao Li Hongmei Lian Haojie Li Yufang Xu Huiyong Zhang | 2021 | Journal of Integrative Plant Biology2021，63，8： | 3 |
| 11 | TRAF6 polymorphisms not associated with the susceptibility to and severity of sepsis ina Chinese population显示文摘 | YuFang Lu Zhang Gang-qiao Zhou Zhi-fu Wang Kai Feng Zhi-yi Lou Wei Pang Lei Li Yan Ling Yu-xia Li Bao-chi Liu | 2010 | World Journal of Emergency Medicine2010，1，3： | 3 |
| 12 | Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospective cohort study显示文摘The association between serum uric acid and the risk of incident diabetes in Chinese adults remains unknown.This study aimed to investigate this association in a community-dwelling population aged≥40 years in Shanghai,China.Oral glucose tole3rance test was conducted during baseline and follow-up visits.Relative risk regression was utilized to examine the associations between baseline gender-specific serum uric acid levels and incident diabetes risk.A total of 613(10.3%)incident diabetes cases were identified during the follow-up visit after 4.5 years.Fasting plasma glucose,postload glucose,and glycated hemoglobin A1c during the follow-up visit progressively increased across the sex-specific quartiles of serum uric acid(all Ps<0.05).The incidence rate of diabetes increased across the quartiles of serum uric acid(7.43%,8.77%,11.47%,and 13.43%).Multivariate adjusted regression analysis revealed that individuals in the highest quartile had 1.36-fold increased risk of diabetes compared with those in the lowest quartile of serum uric acid(odds ratio(95%confidence interval)=1.36(1.06−1.73)).Stratified analysis indicated that the association was only observed in women.Accordingly,serum uric acid was associated with the increased risk of incident diabetes among middle-aged and elderly Chinese women. | Di Cheng Chunyan Hu Rui Du Hongyan Qi Lin Lin Xueyan Wu Lina Ma Kui Peng Mian Li Min Xu Yu Xu Yufang Bi Weiqing Wang Yuhong Chen Jieli Lu | 2020 | Frontiers of Medicine2020，14，6： | 3 |
| 13 | Threshold for neural tube defect risk by accumulated singleton loss-of-function variants显示文摘 | Zhongzhong Chen Yunping Lei Yufang Zheng Vanessa Aguiar-Pulido M. Elizabeth Ross Rui Peng Li Jin Ting Zhang Richard H. Finnell Hongyan Wang | 2018 | Cell Research2018，28，10： | 3 |
| 14 | Late Quaternary Activity of the Huashan Piedmont Fault and Associated Hazards in the Southeastern Weihe Graben,Central China显示文摘The Weihe Graben is not only an important Cenozoic fault basin in China but also a significant active seismic zone. The Huashan piedmont fault is an important active fault on the southeast side of the Weihe Graben and has been highly active since the Cenozoic. The well–known Great Huaxian County Earthquake of 1556 occurred on the Huashan piedmont fault. This earthquake, which claimed the lives of approximately 830000 people, is one of the few large earthquakes known to have occurred on a high–angle normal fault. The Huashan piedmont fault is a typical active normal fault that can be used to study tectonic activity and the associated hazards. In this study, the types and characteristics of late Quaternary deformation along this fault are discussed from geological investigations, historical research and comprehensive analysis. On the basis of its characteristics and activity, the fault can be divided into three sections, namely eastern, central and western. The eastern and western sections display normal slip. Intense deformation has occurred along the two sections during the Quaternary; however, no deformation has occurred during the Holocene. The central section has experienced significant high–angle normal fault activity during the Quaternary, including the Holocene. Holocene alluvial fans and loess cut by the fault have been identified at the mouths of many stream valleys of the Huashan Mountains along the central section of the Huashan piedmont fault zone. Of the three sections of the Huashan piedmont fault, the central section is the most active and was very active during the late Quaternary. The rate of normal dip–slip was 1.67–2.71±0.11 mm/a in the Holocene and 0.61±0.15 mm/a during the Mid–Late Pleistocene. As is typical of normal faults, the late Quaternary activity of the Huashan piedmont fault has produced a set of disasters, which include frequent earthquakes, collapses, landslides, mudslides and ground fissures. Ground fissures mainly occur on the hanging–wall of the Huashan piedmont fault, with landslides, collapses and mudslides occurring on the footwall. | DU Jianjun LI Dunpeng WANG Yufang MA Yinsheng | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 3 |
| 15 | The prevalence of thyroid nodules and its relationship with metabolic parameters in a Chinese community-based population aged over 40 years显示文摘 | Hongwei Guo Min Sun Wei He Huanhuan Chen Wen Li Jinmei Tang Wei Tang Jieli Lu Yufang Bi Guang Ning Tao Yang Yu Duan | 2014 | Endocrine2014，，： | 2 |
| 16 | Ligustrazine facilitates hair cell regeneration in the cochlea following gentamicin ototoxicity显示文摘BACKGROUND:Ligustrazine(tetramethylpyrazine) decreases ototoxicity induced by gentamicin and facilitates hair cell regeneration and repair,but the precise mechanisms remain controversial.OBJECTIVE:To explore the protective effects of ligustrazine on gentamicin ototoxicity by determining heat shock protein 70 mRNA and protein expression in the cochlear stria vascularis of guinea pigs at different time points.DESIGN,TIME AND SETTING:The randomized,controlled study was performed at the Laboratory of Physiology,Shenyang Medical College of China in 2007.MATERIALS:Ligustrazine parenteral solution(Qiqihar Pharmaceutical Factory,China) and gentamicin sulfate(Shenyang First Pharmaceutical Factory,China) were used in this experiment.METHODS:White guinea pigs with red eyes were randomly intraperitoneally administered gentamicin sulfate injection + saline,gentamicin sulfate injection + ligustrazine,and ligustrazine + saline,respectively.MAIN OUTCOME MEASURES:Auditory brainstem response threshold was measured.Immunohistochemistry,in situ hybridization,and image analyzing techniques were utilized to determine heat shock protein 70 mRNA and protein expression in cochlear stria vascularis of guinea pigs.RESULTS:Following gentamicin ototoxicity,the auditory brainstem response threshold increased,peaked on day 3,and then decreased with increased time after drug withdrawal.The auditory brainstem response threshold was significantly diminished following ligustrazine intervention,but recovered to normal on day 30(P > 0.05).Heat shock protein 70 expression also increased,peaked on day 3,and then decreased in the cochlear stria vascularis of guinea pigs following gentamicin ototoxicity.Ligustrazine intervention resulted in decreased heat shock protein 70 expression in the cochlear stria vascularis,which recovered to normal on day 14.Heat shock protein 70 mRNA expression increased in the cochlear stria vascularis following gentamicin ototoxicity,but ligustrazine intervention resulted in decreased levels.CONCLUSION:Ligustrazine significantly ameliorated gentamicin ototoxicity by reducing heat shock protein 70 mRNA and protein expression in the cochlear stria vascularis. | Liang Zhang Yueqiu Ni Yufang Li Wenshuang Fu | 2010 | Neural Regeneration Research2010，5，10： | 2 |
| 17 | A Comparative Study of Ionospheric Correction on SAR Interferometry—A Case Study of L’Aquila Earthquake显示文摘Synthetic Aperture Radar Interferometry(InSAR)has shown its potential on seismic deformation monitoring since it can achieve the accuracy of centimeter level or even the millimeter level.However,the irregular varieties of ionosphere can induce the additional phase delay on SAR interferometry,restricting its further application in high-precision deformation monitoring.Although several methods have been proposed to correct the ionospheric phase delay on SAR interferometry,the performances of them haven't been evaluated and compared.In this study,three commonly used methods,including polynomial fitting,azimuth offset and split-spectrum are applied to L'Aquila Earthquake to correct the ionospheric phase delay on two Phased Array type L-band Synthetic Aperture Radar(PALSAR)onboard the Advanced Land Observing Satellite-1(ALOS-1)images.The result indicates that these three methods can effectively correct the ionospheric phase delay error for SAR interferometry,where the standard deviations of the ionosphere-corrected results have decreased by almost a factor of 1.8 times for polynomial fitting method,4.2 times for azimuth offset method and 2.5 times for split-spectrum method,compared to those of the original phase.Furthermore,the result of the sliding distribution inversion of the seismic fault shows the best performance for split-spectrum method. | Yufang HE Wu ZHU Yang LEI Qin ZHANG Zhenhong LI | 2022 | Journal of Geodesy and Geoinformation Science2022，5，1： | 2 |
| 18 | Methodological exploration on the construction of a traditional Chinese medicine nursing expert consensus based on evidence--taking stroke as an example显示文摘Objective: To explore the methodology of the evidence-based expert consensus formulation process of traditional Chinese medicine(TCM) nursing taking stroke as an example.Methods: First, preliminary and comprehensive presentation of all stroke-related symptoms and corresponding TCM nursing techniques involved were revealed through bibliometric analysis. Then, selection of stroke symptoms and TCM nursing techniques for inclusion in the consensus was performed using an expert consultation method. Next, we determined the search strategy for a precise evidence search;conducted an evaluation of evidence quality and the grade of the evidence;and completed evidence extraction, evidence analysis, and evidence synthesis based on the included symptoms and TCM nursing techniques. The Delphi method was then applied to determine the strength of each recommendation and the choice of nursing care points by referring to the Grading of Recommendations, Assessment, Development, and Evaluations grid. Finally, we conducted an external expert validation of the Delphi results to form an expert consensus guideline.Results: Through the bibliometric analysis, 22 stroke symptoms and 18 TCM nursing techniques were identified in the literature. Then, after expert consultation, 22 symptoms and 111 pairs of symptoms combined with TCM nursing techniques were selected for the evidence search. Evidence integration yielded 10 stroke symptoms corresponding to 29 bodies of evidence;these 10 symptoms were retained through the Delphi consultation, and recommendation strength results for 26 recommendations were obtained. A total of 9 symptoms were further retained for expert external validation to form 24 recommendations, with a recommendation process score range of 7.64-9.99 points and a more scientific and standardized recommendation-formation process.Conclusion: Owing to the current limited conditions of evidence-based resources for TCM nursing, the present consensus-building process represents only a preliminary exploration of an evidence-based expert consensus for TCM nursing to provide a reference for a more scientific and standardized methodology. | Xuejing Li Ke Peng Meiqi Meng Liu Han Dan Yang Junqiang Zhao Yufang Hao | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，2： | 2 |
| 19 | 折合频率对三维跨声速压气机颤振稳定性的影响显示文摘It is well known that fan/compressor blade flutter stability increases with the increase of reduced frequency.Less well-known is that the least stable inter blade phase angle(IBPA)increases with the drop of reduced frequency.However,it is quite striking that little can be found in the open literature about the mechanism to the observations.In this paper,a numerical investigation is carried out to uncover the mechanism of the effect of reduced frequency on flutter stability and the least stable IBPA.The NASA rotor 67 has been used as the test vehicle with its first bending and torsion modes being considered.The time domain harmonic balance method together with the influence coefficient method is used to obtain the worksum-IBPA curves for all cases.It is found that:1)the deterioration of flutter stability with the decrease of reduced frequency is dictated by the dominant decrease of aerodamping due to a blade own vibration;2)the increase of the least stable IBPA with the decrease of reduced frequency arises largely from the increase of the least stable IBPA of the aerodamping from the nearest blade on a blade pressure side. | Ruichao Shi Yufang Li Dingxi Wang | 2022 | 风机技术2022，64，3： | 2 |
| 20 | The ChinaMAP reference panel for the accurate genotypeimputation in Chinese populations显示文摘Dear Editor,The genotype imputation is an efficient and pivotal approach to estimate the unobserved genotypes in the genomic data from the single nucleotide polymorphism(SNP)genotyping arrays or whole-genome sequencing(WGS).The fine mapping of variants in the genome-wide association study(GWAS)could be critically improved by the imputation with an optimal reference panel based on the population-specific haplotypes. | Lin Li Peide Huang Xiaohui Sun Siyu Wang Min Xu Sha Liu Zhimin Feng Qing Zhang Xiaoji Wang Xiaole Zheng Mengyao Dai Yufang Bi Guang Ning Yanan Cao Weiqing Wang | 2021 | Cell Research2021，31，12： | 2 |
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