|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sperm preparation for intracytoplasmic injection: methods and relationship to fertil?ization results显示文摘 | BOURNE H RICHINGS N LIU DY | 1995 | Reprod Fertil Dev1995，7，2： | 1 |
| 2 | Future challen-ges of flash memory technologies显示文摘 | LU Chihyuan Hsieh Kuangyeu LIU Rich | 2009 | Microelectronic Engi-neering2009，86，3： | 1 |
| 3 | Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions 显示文摘 | Liu H Rich ES Godley L | 2011 | Blood2011，118，： | 1 |
| 4 | Do children wit h falling blood lead levels have improved cognition显示文摘 | Liu X Diet rich KN Radcliffe J | 2002 | Pediatrics2002，110，4： | 1 |
| 5 | Metabolomic investigation of the ethnopharmacological use of Artemisia aria with NMR spectroscopy and multivariate data analysis 显示文摘 | Liu NQ Cao M Fr6 d6 rich M | 2010 | Journal of Ethnopharmacology2010，128，1： | 1 |
| 6 | Sperm preparation for intracytoplasmic injection:methods and relationship to fertilization results显示文摘 | Bourne H Richings N Liu DY | 1995 | Reprod Fertil Dev1995，7，2： | 1 |
| 7 | Comparison of attitudes regard- ing preimplantation genetic diagnosis among patients with hered- itary cancer syndromes显示文摘 | Rich TA Liu M Etzel CJ | 2014 | Fam Cancer2014，13，2： | 1 |
| 8 | Reduced-intensity conditioning with combined haploidentical and cord blood transplantat ion results in rapid engraftment, low GVHD, and durable remissions 显示文摘 | Liu H Rich ES Godley L | 2011 | Blood2011，118，： | 1 |
| 9 | Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway显示文摘 | Shideng Bao Gaoliang Ouyang Xuefang Bai Zhi Huang Chaoyu Ma Ming Liu Rong Shao Ryan M Anderson Jeremy N Rich Xiao-Fan Wang | 2004 | Cancer Cell2004，，4： | 1 |
| 10 | Electrochemical micro-aptasensors for exosome detection based on hybridization chain reaction amplification显示文摘Exosomes are cell-derived nanovesicles that have recently gained popularity as potential biomarkers in liquid biopsies due to the large amounts of molecular cargo they carry,such as nucleic acids and proteins.However,most existing exosome-based analytical sensing methods struggle to achieve high sensitivity and high selectivity simultaneously.In this work,we present an electrochemical micro-aptasensor for the highly sensitive detection of exosomes by integrating a micropatterned electrochemical aptasensor and a hybridization chain reaction(HCR)signal amplification method.Specifically,exosomes are enriched on CD63 aptamer-functionalized electrodes and then recognized by HCR products with avidin-horseradish peroxidase(HRP)attached using EpCAM aptamers as bridges.Subsequently,the current signal that is generated through the enzyme reaction between the HRP enzyme and 3,3,,5/5,-tetramethylbenzidine(TMB)/H_(2)0_(2) directly correlates to the amount of bound HRP on the HCR products and thus to the number of target exosomes.By introducing anti-EpCAM aptamers,micro-aptasensors can detect cancerous exosomes with high specificity.Due to the micropatterned electrodes and HCR dual-amplification strategy,the micro-aptasensors achieve a linear detection response for a wide range of exosome concentrations from 2.5×10^(3) to 1×10^(7) exosomes/mL,with a detection limit of 5×10^(2) exosomes/mL.Moreover,our method successfully detects lung cancer exosomes in serum samples of early-stage and late-stage lung cancer patients,showcasing the great potential for early cancer diagnosis. | Wenfen Zhang Zhenhua Tian Shujie Yang Joseph Rich Shuaiguo Zhao Mikael Klingeborn Po-Hsun Huang Zhishang Li Alexander Stout Quinn Murphy Edward Patz Shusheng Zhang Guozhen Liu Tony Jun Huang | 2021 | Microsystems & Nanoengineering2021，7，4： | 1 |
| 11 | Swallowing function after transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer显示文摘 | Rich JT Liu J Haughey BH | | 0，，： | 1 |
| 12 | Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway显示文摘 | Shideng Bao Gaoliang Ouyang Xuefang Bai Zhi Huang Chaoyu Ma Ming Liu Rong Shao Ryan M Anderson Jeremy N Rich Xiao-Fan Wang | 2004 | Cancer Cell2004，，4： | 1 |
| 13 | Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete 1L-4 显示文摘 | Liu L Rich BE lnobe J-I | 1998 | lnt lmmunol1998，10，8： | 1 |
| 14 | Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds 显示文摘 | Holmes TC de Lacalle S Su X Liu G Rich A Zhang S | 2000 | Proc Natl Acad Sci U S A2000，97，： | 1 |
| 15 | 连续油管完整性监测和管理显示文摘连续油管在起下钻期间易于磨损和疲劳。一种新型井场扫描系统通过连续监测油管的异常情况帮助作业公司最大限度地减少油管过早损坏问题。钻井和增产技术的进步正在为非常规资源的开发勘探新的油气远景区。这些远景区的成功开发在很大程度上取决于作业公司最大限度地增加井眼与油气藏的接触面积并开采油气藏的能力。 | Rich Christie Zhanke Liu Roderic Stanley Michelle Torregrossa Andrew Zheng Liam Zsolt | 2016 | 国外测井技术2016，37，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员