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1586篇 您的检索式:作者名="Li N B"
    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Thioredoxin interacting protein,a key molecular switch between oxidative stress and sterile inflammation in cellular response显示文摘Tissue and systemic inflammation have been the main culprit behind the cellular response to multiple insults and maintaining homeostasis.Obesity is an independent disease state that has been reported as a common risk factor for multiple metabolic and microvascular diseases including nonalcoholic fatty liver disease(NAFLD),retinopathy,critical limb ischemia,and impaired angiogenesis.Sterile inflammation driven by high-fat diet,increased formation of reactive oxygen species,alteration of intracellular calcium level and associated release of inflammatory mediators,are the main common underlying forces in the pathophysiology of NAFLD,ischemic retinopathy,stroke,and aging brain.This work aims to examine the contribution of the pro-oxidative and pro-inflammatory thioredoxin interacting protein(TXNIP)to the expression and activation of NLRP3-inflammasome resulting in initiation or exacerbation of sterile inflammation in these disease states.Finally,the potential for TXNIP as a therapeutic target and whether TXNIP expression can be modulated using natural antioxidants or repurposing other drugs will be discussed.Islam N Mohamed Luling Li Saifudeen Ismael Tauheed Ishrat Azza B El-Remessy 2021World Journal of Diabetes2021,12,12:6
3持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 2016中华高血压杂志2016,24,11:4
4肠道微生态失调与高血压的关系显示文摘新出现的证据表明,肠道菌群是维持生理动态平衡的关键,该研究旨在验证微生态失衡的肠道菌群与高血压相关这一假设,因为遗传、环境和膳食因素对肠道菌群和血压有很大影响。方法:从2种高血压模型大鼠和一个小队列患者人群的粪便样本中提取细菌DNA,用于细菌基因组的分析.刘莉 叶鹏 Yang T Santisteban MM Rodriguez V Li E Ahmari N Carvajal JM Zadeh M Gong M Qi Y Zubcevic J Sahay B Pepine CJ Raizada MK Mohamadzadeh M 2015中华高血压杂志2015,23,5:4
5Skin toxicity determined in vitro by three- dimensional,native-state histoculture显示文摘Li L N Margolis L B Hoffman R M 1991Proc Natl Acad Sci USA1991,88,:2
6Review of Recent Progress in Solid-State Dye-Sensitized Solar Cells显示文摘Li B Wang L D Kang B N 2006Solar Energy Materials and Solar Cells2006,90,5:1
7Phenolic and triterpenoid glycosides from Aster batangensis 显示文摘SHAO Y LI Y L ZHOU B N 1996Phytochemistry1996,41,6:1
8Investigation of an arbitrary oriented crack meeting an interface between two elastic materials显示文摘Li J Zhang X B Recho N 1997Eur J Mech A:Soids1997,16,5:1
9Transitional cell carcinoma in renal transplant recipients: a single cen- ter experience显示文摘LI X B Xing N Z Wang Y 2008Int J Urol2008,15,:1
10Network target for screening syner- gistic drug combinations with application to traditional Chinese medicine显示文摘Li S Zhang B Zhang N B 2011BMC Syst Biol2011,5,10:1
11Characteriza-tion of Products Recycling from PCB Waste Pyrolysis显示文摘QUAN C LI A M GAO N B 2010Journal of Analytical and Applied Pyrolysis2010,89,:1
12Effect of Mo ad-dition on the microstructure and mechanical properties ofultra-fine grade TiC-TiN-WC-Mo2C-Co cermets 显示文摘Li Y Liu N Zhang X B Rong C L 2008In-ternational Journal of Refractory Metals and Hard Materi-als2008,26,3:1
13Synthesis of uniform hex- agonal Prismatic ZnO whiskers显示文摘Hu J Q Li Q Wong N B 2002Chem Mater2002,14,3:1
14Searching for a mesh-independent sub-grid model for CFD simulation of gas-solid riser flows显示文摘Lu B N Wang W Li J H 0,,15:1
15Flash pyrolysis of agricultural residues using a plasma heated laminar entrained flow reac- tor显示文摘Xiu S N Yi W M Li B M 2005Biomass and Bioenergy2005,29,:1
16Carbon dioxide solubility in some ionic liquids at moderate pressures显示文摘SORIANO A N DOMA B T LI M 2009Journal of the Taiwan Institute of Chemical Engineers2009,40,4:1
17Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell prolifera- tion and apoptosis显示文摘Xiao B Zhu ED Li N 2012Oncol Rep2012,27,2:1
18Soil supply and nutrient demand (SSAND) :A general nutrient uptake model and an example of its application to forest management显示文摘Comerford N B Cropper W P Li H 2006Canadian Journal of Soil Science2006,86,:1
19Intergrowth and coexistence effects of Ti O2-Sn O2nanocomposite with excellent photocatalytic activity显示文摘Huang M N Yu J H Li B 2015J Alloys Compd2015,629,25:1
20Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals显示文摘Scheid J F Mouquet H Feldhahn N Seaman M S Velinzon K Pietzsch J Ott R G Anthony R M Zebroski H Hurley A Phogat A Chakrabarti B Li Y Connors M Pereyra F Walker B D Wardemann H Ho D Wyatt R T Mascola J R Ravetch J V Nussenzweig M C 2009Nature2009,458,7238:1
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