|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Orbit determination of Chang'E-3 and positioning of the lander and the rover显示文摘Chang’E-3 landed on the east of Sinus Iridum area on December 14,2013,performing China’s first successful soft landing on the lunar surface.We present the results on precision orbit determination and positioning of the lander and the rover.We describe the data,modeling,and methods used to achieve position knowledge over the period December 2–21,2014.In addition to the radiometric X-band range and Doppler tracking data,delta differential one-way ranging data are also used in the calculation,which show that they strongly improve the accuracy of the orbit reconstruction.Total position overlap differences are about 20 and 30 m for the 100 km 9 100 km and100 km9 15 km lunar orbit,respectively,increased by*50%with respect to CE-2 and at the same level as other lunar spacecrafts of recent era such as SELENE and lunar reconnaissance orbiter(LRO).The position error of the soft landing trajectory is less than 100 m.A kinematic statistical method is applied to determine the position of the lander and relative position of the rover with respect to the lander.The position difference of the lander is better than50 m compared to LRO photograph result.Compared with the delta very long baseline interferometry(VLBI)group delay between the lander and the rover,the delta VLBI phase delay can improve the relative position of the rover from*1,000 to*1 m. | Yong Huang Shengqi Chang Peijia Li Xiaogong Hu Guangli Wang Qinghui Liu Weimin Zheng Min Fan | 2014 | Chinese Science Bulletin2014，59，29： | 28 |
| 2 | A new classification of seepage control mechanisms in geotechnical engineering显示文摘Seepage flow through soils,rocks and geotechnical structures has a great influence on their stabilities and performances,and seepage control is a critical technological issue in engineering practices.The physical mechanisms associated with various engineering measures for seepage control are investigated from a new perspective within the framework of continuum mechanics;and an equation-based classification of seepage control mechanisms is proposed according to their roles in the mathematical models for seepage flow,including control mechanisms by coupled processes,initial states,boundary conditions and hydraulic properties.The effects of each mechanism on seepage control are illustrated with examples in hydroelectric engineering and radioactive waste disposal,and hence the reasonability of classification is demonstrated.Advice on performance assessment and optimization design of the seepage control systems in geotechnical engineering is provided,and the suggested procedure would serve as a useful guidance for cost-effective control of seepage flow in various engineering practices. | Yifeng Chen Ran Hu Chuangbing Zhou Dianqing Li Guan Rong Qinghui Jiang | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，3： | 10 |
| 3 | Effects of Dietary Stachyose on Growth Performance, Digestive Enzyme Activities and Intestinal Morphology of Juvenile Turbot(Scophthalmus maximus L)显示文摘A 12-week feeding trial was conducted to evaluate the effects of dietary stachyose on the growth performance, digestive enzymes activities and intestinal structures of juvenile turbot(Scophthalmus maximus L). Five isonitrogenous(49.58% crude protein) and isolipidic(10.50% crude lipid) diets were formulated to contain 0(Control), 0.625%(S-0.625), 1.25%(S-1.25), 2.5%(S-2.5) and 5%(S-5) stachyose, respectively. With the increase of stachyose level, the growth performance and feed utilization of turbot, such as the specific growth rate, final mean body weight, weight gain rate and feed efficiency, increased significantly(P < 0.05) and then stabilized. The feed intake of fish fed S-5 was significantly higher(P < 0.05) than that of fish in other groups. The activities of trypsin, intestinal caseinolytic, stomach and intestinal amylase were significantly influenced by stachyose(P < 0.05). The highest values of trypsin and intestinal caseinolytic activities were observed in group S-1.25, while the highest activity of stomach amylase and the lowest activity of intestine amylase were observed in group S-5. No lesion or damage was found on the distal intestine structures of fish from all treatments, while the height of simple folds in the distal intestine was significantly increased(P< 0.05) when 1.25% or 2.5% stachyose was added in the diets. These results indicated that moderate level of stachyose(1.25%) improves the growth performance, feed utilization, digestive enzyme activities and the distal intestine structures of juvenile turbot. | HU Haibin ZHANG Yanjiao MAI Kangsen AI Qinghui XU Wei ZHANG Wenbing LI Yanxian LIU Jintao | 2015 | Journal of Ocean University of China2015，14，5： | 10 |
| 4 | Occurrence, polarity and bioavailability of dissolved organic matter in the Huangpu River,China显示文摘Dissolved organic matter(DOM)plays an important role in biogeochemical cycles in aquatic ecosystem.To investigate the characteristics of DOM in Huangpu River(the last tributary of the Yangtze River),surface water samples were collected along the river from December2011 to June,2013.The concentrations of dissolved organic carbon(DOC),the absorbance and fluorescence spectrum of DOM in water samples were measured.Fluorescent DOM in the Huangpu River was decomposed into four components by the parallel factor analysis(PARAFAC),including one humic-like substance and three protein-like substances.It showed that high spatial variability of DOC concentration was observed in the upstream water compared to the downstream water,and so did the absorbance coefficients of chromophoric dissolved organic matter and the total fluorescence intensities of different PARAFAC components of DOM.Furthermore,there was a large difference between the polarity and bioavailability of DOM in the Huangpu River.Polar compounds dominated tyrosine-like component of fluorescent DOM in all seasons.Tryptophan-like and humic-like substances had more polar fraction in summer and autumn than those in winter,while aromatic protein-like materials had the highest polar fraction in winter.Almost all of fluorescent DOM components were refractory in spring,while less than 20%of fluorescent DOM in average were biodegradable within 4 weeks in other seasons.We concluded that the spatial variation in the abundance of DOM in the Huangpu River is mainly affected by the water discharges from the Hangjiahu Plain and the seasonal difference in polarity and bioavailability of DOM is largely determined by its origins. | Qianqian Dong Penghui Li Qinghui Huang Ahmed A.Abdelhafez Ling Chen | 2014 | Journal of Environmental Sciences2014，26，9： | 7 |
| 5 | Low-latency deep-reinforcement learning algorithm for ultrafast fiber lasers显示文摘The application of machine learning to the field of ultrafast photonics is becoming more and more extensive.In this paper,for the automatic mode-locked operation in a saturable absorber-based ultrafast fiber laser(UFL),a deep-reinforcement learning algorithm with low latency is proposed and implemented.The algorithm contains two actor neural networks providing strategies to modify the intracavity lasing polarization state and two critic neural networks evaluating the effect of the actor networks.With this algorithm,a stable fundamental modelocked(FML)state of the UFL is demonstrated.To guarantee its effectiveness and robustness,two experiments are put forward.As for effectiveness,one experiment verifies the performance of the trained network model by applying it to recover the mode-locked state with environmental vibrations,which mimics the condition that the UFL loses the mode-locked state quickly.As for robustness,the other experiment,at first,builds a database with UFL at different temperatures.It then trains the model and tests its performance.The results show that the average mode-locked recovery time of the trained network model is 1.948 s.As far as we know,it is 62.8%of the fastest average mode-locked recovery time in the existing work.At different temperatures,the trained network model can also recover the mode-locked state of the UFL in a short time.Remote algorithm training and automatic mode-locked control are proved in this work,laying the foundation for long-distance maintenance and centralized control of UFLs. | QIUQUAN YAN QINGHUI DENG JUN ZHANG YING ZHU KE YIN TENG LI DAN WU TIAN JIANG | 2021 | Photonics Research2021，9，8： | 7 |
| 6 | An Intra-Oceanic Subduction System Influenced by Ridge Subduction in the Diyanmiao Subduction Accretionary Complex of the Xar Moron Area,Eastern Margin of the Central Asian Orogenic Belt显示文摘This study focuses on the geology,geochemistry,Sr-Nd isotopes and their tectonic settings of three types of basalts in Diyanmiao ophiolite in the Xar Moron area located on the eastern margin of the Central Asian Orogenic Belt.Type I basalts are oceanic tholeiites with a depleted light rare earth element(LREE)pattern,which are similar to the typical N-mid-oceanic ridge basalt(MORB)and suggests that they were formed at a mid-oceanic ridge.The initial 87Sr/86Sr ratios of Type I basalts range from 0.703966 to 0.705276 and theεNd(t)values are from 16.49 to 17.15,indicating that they were derived from a depleted mantle source.Type II basalts belong to the medium-potassium calc-akaline series and have the geochem-ical characteristics of Nb-enriched basalt(NEB)with high Nb content(14.5 ppm)and strong enrichment in LREEs,implying that they were created by the partial melting of mantle wedge peridotite that previously metasomatized by slab melts.Type III basalts are high-Al basalt(HAB)with high-Al contents(Al_(2)0_(3)=16.75 wt.%-18.00 wt.%),distinct Nb depletion and high Th/Yb ratios.Thus they were likely gen-erated in a normal island-arc setting.Therefore,the association of MORB,NEB,and HAB in the study area may be due to the subduction of a mid-oceanic ridge,and the Diyanmiao ophiolite is proposed to be formed in the forearc setting of a mid-oceanic ridge subduction system. | Yang Cheng Qinghui Xiao Tingdong Li Liquan Xu Yuxu Fan Yan Li Lingjun Guo Jinli Pang Weiming Yuan | 2021 | Journal of Earth Science2021，32，1： | 6 |
| 7 | Morphological changes in interstitial cells of Cajal in the deep muscular plexus and enteric motor neurons of the intestine in rats with multiple organ dysfunction syndrome显示文摘BACKGROUND:Gastrointestinal motility dysfunction in multiple organ dysfunction syndrome(MODS) has been reported to be related to damage to interstitial cells of Cajal(ICC).In the enteric nervous system,ICC and smooth muscle cells are connected in a network to form a special functional unit.Many gastrointestinal motility dysfunction diseases are associated with damage to this network.OBJECTIVE:To investigate the morphological changes of intestinal ICC,and to explore the mechanisms underlying gastrointestinal motility dysfunction in rats with MODS.DESIGN,TIME AND SETTING:The randomized,controlled,experiment was performed at the Central Laboratory of the First Affiliated Hospital of Dalian Medical University of China between June 2007 and March 2009.MATERIALS:Escherichia coli(E.coli strain O127 H6) and bovine serum albumin were purchased from Sigma,USA.METHODS:A total of 40 Wistar rats were equally and randomly divided into MODS group and control group.Suspension of E.coli strain O127 H6 containing BaSO4 and saline were sterilely injected into the abdominal cavity of rats in the MODS and control groups,respectively.MAIN OUTCOME MEASURES:Immunohistochemical double-staining and confocal laser scanning microscopy were used to observe the morphological changes in intestinal cholinergic nerves and ICC in the deep muscular plexus network.Electron microscopy was employed to evaluate the ultrastructural features of ICC in the deep muscular plexus of rats with MODS.RESULTS:Compared with the control group,the distributions and densities of cholinergic/nitrergic nerves and ICC in the deep muscular plexus were significantly decreased in the MODS group(P < 0.01).The enteric nerve-ICC network were disrupted.CONCLUSION:There is ultrastructural injury in the ICC in the deep muscular plexus and enteric nerves of the intestine in rats with MODS,which may be associated with the dysmotility of the gastrointestinal tract in MODS. | Zhengxu Cai Yi Li Qinghui Qi | 2010 | Neural Regeneration Research2010，5，8： | 5 |
| 8 | Remote Sensing Retrieval of Surface Suspended Sediment Concentration in the Yellow River Estuary显示文摘Accurate assessment of surface suspended sediment concentration(SSSC) in estuary is essential to address several important issues: erosion, water pollution, human health risks, etc. In this study, an empirical cubic retrieval model was developed for the retrieval of SSSC from Yellow River Estuary. Based on sediments and seawater collected from the Yellow River and southeastern Laizhou Bay, SSSC conditions were reproduced in the laboratory at increasing concentrations within a range common to field observations. Continuous spectrum measurements of the various SSSCs ranging from 1 to 5700 mg/l were carried out using an Ava Field-3 spectrometer. The results indicated the good correlation between water SSSC and spectral reflectance(Rrs) was obtained in the spectral range of 726–900 nm. At SSSC greater than 2700 mg/L, the 740–900 nm spectral range was less susceptible to the effects of spectral reflectance saturation and more suitable for retrieval of high sediment concentrations. The best correlations were obtained for the reflectance ratio of 820 nm to 490 nm. Informed by the correlation between Rrs and SSSC, a retrieval model was developed(R2 = 0.992). The novel cubic model, which used the ratio of a near-infrared(NIR) band(740–900 nm) to a visible band(400–600 nm) as factors, provided robust quantification of high SSSC water samples. Two high SSSC centers, with an order of 103 mg/l, were found in the inversion results around the abandoned Diaokou River mouth, the present Yellow River mouth to the abandoned Qingshuigou River mouth. There was little sediment exchange between the two high SSSC centers due to the directions of the residual currents and vertical mixing. | ZHAN Chao YU Junbao WANG Qing LI Yunzhao ZHOU Di XING Qinghui CHU Xiaojing | 2017 | Chinese Geographical Science2017，27，6： | 5 |
| 9 | Retrieve Sea Surface Salinity Using Principal Component Regression Model Based on SMOS Satellite Data显示文摘The sea surface salinity(SSS) is a key parameter in monitoring ocean states. Observing SSS can promote the understanding of global water cycle. This paper provides a new approach for retrieving sea surface salinity from Soil Moisture and Ocean Salinity(SMOS) satellite data. Based on the principal component regression(PCR) model, SSS can also be retrieved from the brightness temperature data of SMOS L2 measurements and Auxiliary data. 26 pair matchup data is used in model validation for the South China Sea(in the area of 4?–25?N, 105?–125?E). The RMSE value of PCR model retrieved SSS reaches 0.37 psu(practical salinity units) and the RMSE of SMOS SSS1 is 1.65 psu when compared with in-situ SSS. The corresponding Argo daily salinity data during April to June 2013 is also used in our validation with RMSE value 0.46 psu compared to 1.82 psu for daily averaged SMOS L2 products. This indicates that the PCR model is valid and may provide us with a good approach for retrieving SSS from SMOS satellite data. | ZHAO Hong LI Changjun LI Hongping LV Kebo ZHAO Qinghui | 2016 | Journal of Ocean University of China2016，15，3： | 5 |
| 10 | Protective Effect of Holothurian Intestine Against Indomethacin Induced Gastric Mucosal Damage in Rats显示文摘Our study aimed to investigate the protective effects of Holothurian intestines(HI) on NSAIDs-induced gastric mucosal damage and the possible mechanism. At first, 60 male Wistar rats were induced of gastric lesions with indomethacin(IDM, 30 mg kg^(-1)). The rats were pretreated for 15 consecutive days with saline, sucralfate, or HI(0.4g kg^(-1) d-1, 0.8 g kg^(-1) d^(-1) and 1.6 g kg^(-1) d^(-1)) prior to IDM treatment, followed by evaluations of macroscopic damage and microscopic features; and investigation of the levels of inflammatory cytokines, oxidative stress parameters, gastric mucosal prostaglandin E2(PGE2) and total hexosamine in tissues. The expression of COX-1 and COX-2 m RNA in the gastric tissue were determined by quantitative polymerase chain reaction(q PCR). Pathological gastric ulcer indexes, levels of pro-inflammatory cytokines(IL-1β, IL-17, TNF-α) and lipid peroxidation were significantly decreased in HI-treated groups, whereas the levels of protective factors(TGF-β, GSH, SOD activity and PGE2) were significantly elevated especially in the group with HI 1.61 g kg^(-1) d^(-1)(P < 0.05). Furthermore, the expression of COX-2 mRNA decreased significantly in HI groups(P < 0.05). The study investigates that holothurian intestines may act as a kind of marine medicine which have protective effect on IDM-induced gastric ulcer, which could be a dietary preventive agent for the prevention of gastric damage. | LI Xiaoyu QIAO Xuejing ZHANG Cuiping GAO Hua NIU Qinghui WU Tong ZHANG Qi TIAN Zibin | 2017 | Journal of Ocean University of China2017，16，3： | 4 |
| 11 | Dietary Leucine Requirement for Juvenile Large Yellow Croaker Pseudosciaena crocea (Richardson,1846)显示文摘Dietary leucine requirement for juvenile large yellow croaker, Pseudosciaena crocea Richardson 1846 (initial body weight 6.0 g±0.1 g) was determined using dose-response method.Six isonitogenous (crude protein 43%) and isoenergetic (19 kJ g-1) practical diets containing six levels of leucine (Diets 1-6) ranging from 1.23% to 4.80% (dry matter) were made at about 0.7% increment of leucine.Equal amino acid nitrogen was maintained by replacing leucine with glutamic acid.Triplicate groups of 60 individuals were fed to apparent satiation by hand twice daily (05:00 and 17:30).The water temperature was 26-32℃, salinity 26-30 and dissolved oxygen approximately 7 mg L-1 during the experimental period.Final weight (FW) of large yellow croaker initially increased with increasing level of dietary leucine but then decreased at further higher level of leucine.The highest FW was obtained in fish fed diet with 3.30% Leucine (Diet 4).FW of fish fed the diet with 4.80% Leucine (Diet 6) was significantly lower than those fed Diet 4.However, no significant differences were observed between the other dietary treatments.Feed efficiency (FE) and whole body composition were independent of dietary leucine contents (P>0.05).The results indicated that leucine was essential for growth of juvenile large yellow croaker.On the basis of FW, the optimum dietary leucine requirement for juvenile large yellow croaker was estimated to be 2.92% of dry matter (6.79% of dietary protein). | LI Yan AI Qinghui MAI Kangsen XU Wei CHENG Zhenyan HE Zhigang | 2010 | Journal of Ocean University of China2010，9，4： | 4 |
| 12 | Spatial-temporal variations in net primary productivity in the Arctic from 2003 to 2016显示文摘The area of Arctic sea ice has dramatically decreased, and the length of the open water season has increased;these patterns have been observed by satellite remote sensing since the 1970 s. In this paper, we calculate the net primary productivity(NPP, calculated by carbon) from 2003 to 2016 based on sea ice concentration products,chlorophyll a(Chl a) concentration, photosynthetically active radiation(PAR), sea surface temperature(SST), and sunshine duration data. We then analyse the spatiotemporal changes in the Chl a concentration and NPP and further investigate the relations among NPP, the open water area, and the length of the open water season. The results indicate that(1) the Chl a concentration increased by 0.025 mg/m^3 per year;(2) the NPP increased by 4.29 mg/(m^2·d) per year, reaching a maximum of 525.74 mg/(m^2·d) in 2016;and(3) the Arctic open water area increased by 57.23×10^3 km^2/a, with a growth rate of 1.53 d/a for the length of the open water season. The annual NPP was significantly positively related to the open water area, the length of the open water season and the SST.The daily NPP was also found to have a lag correlation with the open water area, with a lag time of two months.With global warming, NPP has maintained an increasing trend, with the most significant increase occurring in the Kara Sea. In summary, this study provides a macroscopic understanding of the distribution of phytoplankton in the Arctic, which is valuable information for the evaluation and management of marine ecological environments. | Haili Li Changqing Ke Qinghui Zhu Su Shu | 2019 | Acta Oceanologica Sinica2019，38，8： | 4 |
| 13 | The integration of transcriptomic and transgenic analyses reveals the involvement of the SA response pathway in the defense of chrysanthemum against the necrotrophic fungus Alternaria sp.显示文摘Chrysanthemum morifolium cv.‘Huaihuang’has ornamental,edible,medicinal,and tea product uses.However,its field growth,yield,and quality are negatively affected by black spot disease caused by Alternaria sp.(Strain:HQJH10092301;GenBank accession number:KF688111).In this study,we transcriptionally and transgenically characterized a new cultivar,‘Huaiju 2#’(Henan Traditional Chinese Medicine Plant Cultivar identification number:2016002),which was bred from‘Huaihuang’and shows resistance to Alternaria sp.Numerous‘Huaiju 2#’plants were inoculated with Alternaria sp.for three or five days.Metabolic analysis showed increases in both salicylic acid(SA)and jasmonic acid(JA)in infected plants compared to the control.Protein activity analysis also revealed a significant increase in defense enzyme activities in infected plants.RNA-Seq of plants infected for 3 or 5 days produced a total of 58.6 GB of clean reads.Among these reads,16,550 and 13,559 differentially expressed genes(DEGs)were identified in Cm_3 dpi(sample from 3 days post-inoculation labeled as Cm_3 dpi)and Cm_5 dpi(sample from 5 days post-inoculation labeled as Cm_5 dpi),respectively,compared with their controls(Cm_0 d:a mixture samples from 0 d(before inoculation)and those treated with sterile distilled water at 3 dpi and 5 dpi).Gene annotation and cluster analysis of the DEGs revealed a variety of defense responses to Alternaria sp.infection,which were characterized by increases in resistance(R)proteins and the reactive oxygen species(ROS),Ca2+,mitogen-activated protein kinase(MAPK),and JA signaling pathways.In particular,SA signaling was highly responsive to Alternaria sp.infection.The qPCR analysis of 12 DEG candidates supported their differential expression characterized by using the RNA-Seq data.One candidate was CmNPR1(nonexpressor of pathogenesis-related gene 1),an important positive regulator of SA in systemic acquired resistance(SAR).Overexpression of CmNPR1 in‘Huaiju 2#’increased the resistance of transgenic plants to black spot.These findings indicate that the SA response pathway is likely involved in the defense of‘Huaiju 2#’against Alternaria sp.pathogens. | Xiting Zhao Lingyu Song Liwei Jiang Yuting Zhu Qinghui Gao Dandan Wang Jing Xie Meng Lv Ping Liu Mingjun Li | 2020 | Horticulture Research2020，7，1： | 3 |
| 14 | A 3D-bioprinted scaffold with doxycycline-controlled BMP2-expressing cells for inducing bone regeneration and inhibiting bacterial infection显示文摘Large bone defects face a high risk of pathogen exposure due to open wounds,which leads to high infection rates and delayed bone union.To promote successful repair of infectious bone defects,fabrication of a scaffold with dual functions of osteo-induction and bacterial inhibition is required.This study describes creation of an engineered progenitor cell line(C3H10T1/2)capable of doxycycline(DOX)-mediated release of bone morphogenetic protein-2(BMP2).Three-dimensional bioprinting technology enabled creation of scaffolds,comprising polycaprolactone/mesoporous bioactive glass/DOX and bioink,containing these engineered cells.In vivo and in vitro experiments confirmed that the scaffold could actively secrete BMP2 to significantly promote osteoblast differentiation and induce ectopic bone formation.Additionally,the scaffold exhibited broad-spectrum antibacterial capacity,thereby ensuring the survival of embedded engineered cells when facing high risk of infection.These findings demonstrated the efficacy of this bioprinted scaffold to release BMP2 in a controlled manner and prevent the occurrence of infection;thus,showing its potential for repairing infectious bone defects. | Minqi Wang Hanjun Li Yiqi Yang Kai Yuan Feng Zhou Haibei Liu Qinghui Zhou Shengbing Yang Tingting Tang | 2021 | Bioactive Materials2021，6，5： | 3 |
| 15 | Safety and efficacy of Yupingfeng granules in children with recurrent respiratory tract infection:A randomized clinical trial显示文摘Importance:Recurrent respiratory tract infection(RRTI)is common in children.Inappropriate RRTI treatment will lead to asthma and other diseases,thereby seriously affecting the growth and physical health of children.Immune function modulation can prevent and alleviate childhood RRTI.Yupingfeng(YPF),a patented traditional Chinese medicine(TCM),has immunomodulatory effects and is widely used in China to treat children with RRTI.Objective:To evaluate the safety and efficacy of YPF monotherapy in treating children with RRTI.Methods:This multicenter,randomized,double-blind,double-simulation,noninferiority clinical trial was conducted from January 2015 to August 2017,with an 8-week treatment period and 52-week follow-up after the drug withdrawal.Children aged 2–6 years with RRTI meeting the inclusion and exclusion criteria were enrolled in 13 hospitals in China and divided randomly into three groups(2:2:1 ratio)to receive YPF,pidotimod,or placebo.The primary outcome was the proportion of RRTI returning to normal standard level during the follow-up.The secondary outcomes were reduction in the number of RRTI recurrences,effect on clinical symptoms(in accord with TCM practice),effect per symptom,and safety.The trial was registered at the Chinese Clinical Trials Registry(www.chictr.org.cn)under the unique identifier ChiCTR-IPR-15006847.Results:Three hundred and fifty-one children were enrolled and randomly assigned to 3 groups;124,125,and 61 children in the YPF,pidotimod,and placebo groups,respectively,had completed the trial.During the follow-up,the proportion of RRTI returning to normal standard level was 73.13%,67.15%,and 38.81%with YPF,pidotimod,and placebo,respectively(P<0.0001).The proportion of cases who returned to normal standard level in the YPF group was 34.32%higher than that in the placebo group.The safety profile did not significantly differ among the groups.Interpretation:YPF granules were noninferior to the active control drug pidotimod oral solution for the treatment of RRTI in children,and were superior to placebo,with a high safety profile. | Baoping Xu Xinmin Li Siyuan Hu Yixiao Bao Fengmei Chen Zhimin Chen Yonggang Du Enmei Liu Yufeng Liu Qinghui Mou Baoling Su Bo Wang Jianwen Xu Guiping Xu Qiaozhi Yang Liwei Gao Xiaohui Liu Lei Li Rong Ma Kunling Shen | 2022 | Pediatric Investigation2022，6，2： | 3 |
| 16 | Effect of Dietary Olaquindox on the Growth of Large Yellow Croaker(Pseudosciaena crocea R.) and the Distribution of Its Residues in Fish Tissues显示文摘Olaquindox(OLA), one of quinoxaline-N, N-dioxides, has been put under ban. However it was used as a medicinal feed additive early; it promotes the growth of livestock and prevents them from dysentery and bacterial enteritis. In this study, we evaluated the effect of dietary OLA on the growth of large yellow croaker(Pseudosciaena crocea R.) and the histological distribution of OLA and its metabolite 3-methyl-quinoxaline-2-carboxylic acid(MQCA) in fish tissues. Four diets containing 0(control), 42.5, 89.5 and 277.2 mg kg-1 OLA, respectively, were formulated and tested, 3 cages(1.0 m × 1.0 m × 1.5 m) each diet and 100 juveniles(9.75 ± 0.35 g) each cage. The fish were fed to satiation twice a day at 05:00 am and 17:00 pm for 8 weeks. The survival rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet containing 0 and 277.2 mg kg-1 OLA(P < 0.05), while the weight gain rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet without OLA(control)(P<0.05), but similar to that of fish fed the diet with 277.2 mg kg-1 OLA. Fish fed the diet with 277.2 mg kg-1 OLA had the highest content of OLA and MQCA in liver(3.44 and 0.39 mg kg-1, respectively), skin(0.46 and 0.09 mg kg-1, respectively) and muscle(0.24 and 0.06 mg kg-1, respectively). In average, fish fed the diet containing OLA had the highest content of OLA and MQCA in liver which was followed by skin and muscle(P < 0.05), whereas OLA and MQCA were not detectable in control. Our findings demonstrated that OLA and MQCA accumulated in large yellow croaker when it was fed with the diet containing OLA, thus imposing a potential safety risk to human health. | LI Huitao WANG Weifang MAI Kangsen AI Qinghui ZHANG Chunxiao ZHANG Lu | 2014 | Journal of Ocean University of China2014，13，5： | 3 |
| 17 | Dietary Leucine Requirement of Juvenile Japanese Seabass(Lateolabrax Japonicus)显示文摘A 56-day feeding trial was conducted to examine the dietary leucine requirement of juvenile Japanese seabass in seawater floating net cages(1.5 m × 1.5 m × 2.0 m). Six isonitrogenous(crude protein 40%) and isoenergetic(gross energy 20 k J g-1) diets were formulated to contain different concentrations of leucine(0.9%, 1.49%, 2.07%, 2.70%, 3.30% and 3.88% of dry matter). Crystalline L-amino acids were supplemented to simulate the whole body amino acid pattern of Japanese seabass except for leucine. Three groups(30 fish individuals each, 8.0 g ± 0.20 g in initial weight) were fed to apparent satiation at 5:00 and 17:30 every day. During the experimental period, the water temperature ranged from 26 to 32℃ and salinity from 26 to 30, and the dissolved oxygen was maintained at 7 mg L-1. The results showed that weight gain(WG), nitrogen retention(NR), feed efficiency(FE) and protein efficiency ratio(PER) were significantly increased when dietary leucine was increased from 0.90% to 2.70% of dry matter, and then declined. WG was the highest when fish were fed D4 containing 2.70% of leucine. No significant differences were observed in body composition among dietary treatments(P > 0.05). Considering the change of WG, the optimum dietary leucine requirement of juvenile Japanese seabass was either 2.39% of dry matter or 5.68% of dietary protein. | LI Yan CHENG Zhenyan MAI Kangsen AI Qinghui | 2015 | Journal of Ocean University of China2015，14，1： | 3 |
| 18 | Growth and photosynthesis responses of Phaeodactylum tricornutum to dissolved organic matter from salt marsh plant and sediment显示文摘The effects of allochthonous dissolved organic matter (DOM) on the growth and photosynthesis of Phaeodactylum tricornutum were investigated. P. tricornutum incubated in f/2 medium was exposed to DOM additives, which were extracted from the plant and sediment samples of a salt marsh in North Branch of the Yangtze estuary, China. During 12 days incubation, the chlorophyll fluorescence parameters of P. tricornutum were measured by a Phyto-PAM phytoplankton analyzer. Spectral properties of DOM in algae filtrates were also observed. The concentrations of chlorophyll a, active chlorophyll a, and the maximum quantum yield of photosystem II significantly decreased after four days of incubation, suggesting that the growth and photosynthetic efficiency of P. tricornutum were inhibited. After adding sediment-DOM extract, both a 250 /a 365 (the ratio of the absorption coefficients at 250 and 365 nm) and S values (spectral slope coefficients) of algae filtrates declined in the first two days, which demonstrated a loss of low molecular weight DOM. Parallel factor analysis of fluorescence spectra of DOM in algae filtrates revealed that DOM could be classified into two humic-like and two protein-like components. The fluorescence intensity of tyrosine-like component originating from algae increased significantly during incubation. This study supports the hypothesis that allochthonous DOM derived from salt marsh plant and sediment have a strong influence on the adjacent aquatic ecosystems. | Yihua Xiao Qinghui Huang Ling Chen Penghui Li | 2010 | Journal of Environmental Sciences2010，22，8： | 3 |
| 19 | Organochlorine pesticides characteristics in water column of strategic drinking water sources in the Yangtze estuary显示文摘 | Qinghui HUANG Jianhua LI Jianfu ZHAO Ran XU Li XIE | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 2 |
| 20 | Protective Effects of Oyster Extract Against Hepatic Tissue Injury in Alcoholic Liver Diseases显示文摘Oyster extract is an effective bioactivity component. It has abundant nutritional value and antiviral, antitumor and immune defense functions. The role of oyster extract in treating liver injury has been paid more attention. We use Wistar rats to make alcoholic liver disease model through injecting alcohol into rats' stomachs. These rats were randomly divided into five groups: model group, control group, low-dose, middle-dose and high-dose experimental group with a dose of 0.12 g kg-1, 0.40 g kg-1, and 1.20 g kg-1 alcoholic. After nine weeks, serum biomarkers(ALT, AST, TG and TCHO), malondialdehyde(MDA), glutathione(GSH), C3a, C5a, IL-17, TNF-ɑ, anti-MAA-HAS IgG, CD3+, CD4+, CD8+, NK cell activation and zinc content were assessed. The results showed that the serum biomarkers(ALT, AST, TG and TCHO), MDA content, anti-MAA-HSA IgG, serum C3a, C5a IL-17 and TNF-ɑ levels of oyster extract treatment groups were significantly decreased in comparison with model group. On the contrary, GSH showed adverse trend. Serum CD3+, CD4+ and NK cell activation were significantly increased in middle-dose group and high-dose group compared with model group, and there was decrease of CD8+ activity in high-dose group. Plasma Zn level was decreased in model group compared with that in control group. Meanwhile, Mean plasma Zn levels increased dramatically following the dose increase of a given oyster extract. | ZHANG Cuiping LI Xiaoyu JING Xue ZHANG Bo ZHANG Qi NIU Qinghui WANG Jianjun TIAN Zibin | 2014 | Journal of Ocean University of China2014，13，2： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员