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| 1 | Development of a multiplex one-step real-time RT-PCR assay for the simultaneous detection of eight viruses associated with febrile rash illnesses显示文摘Fever and rash illnesses(FRIs)are a series of common diseaseswith fever and rashes as clinicalmanifestations,most of which are caused by viral infection.The rashes of FRIs are generally nonspecific;therefore it is difficult to identify FRIassociated viruses solely based on clinical symptoms.To achieve rapid and accurate identification of FRI pathogens,a multiplex one-step real-time reverse transcription-polymerase chain reaction(RT-PCR)assay was developed and evaluated in this study.Primers and probes were selected for the detection of measles virus(MeV),rubella virus(RV),human enterovirus(EV),varicella-zoster virus(VZV),dengue virus(DENV),human parvovirus B19(B19),Epstein-Barr virus(EBV),and human herpes virus 6(HHV-6),which cover the most common pathogenic viruses of FRIs.Detection of the eight FRI-associated viruses,which was divided into two groups/tubes,was simultaneously performed under universal optimized reaction conditions in multiplex one-step real-time RT-PCR assay.The multiplex realtime RT-PCR showed high sensitivity and specificity in detecting the eight FRI-associated viruses.The limits of detection(LODs)for the eight viruses were in the range of 47–177 copies/reaction,and no cross reactions for the eight FRIassociated viruses were found in the multiplex assay.In addition,the results of the multiplex real-time RT-PCR assay were consistent with the results of a monoplex real-time RT-PCR assay and sequencing for clinical specimens obtained from FRI patients.With its advantages of high efficiency and rapid and accurate diagnosis,multiplex real-time RT-PCR was very feasible for the early diagnosis of FRI pathogenic viruses and would be of great help for the proper treatment,monitoring,and initiation of preventive measures for FRI cases. | Aili Cui Shulei Wang Qiang Zhang Huiling Wang Zhen Zhu Aqian Li Qinqin Song Yanzhe Hao Jilan He Wenbo Xu Yan Zhang | 2020 | Biosafety and Health2020，2，2： | 5 |
| 2 | Multilayered graphene membrane as an experimental platform to probe nano-confined electrosorption | Chi Cheng Julia Uhe Xiaowei Yang Yanzhe Wu Dan Li | 2012 | Progress in Natural Science:Materials International2012，22，6： | 1 |
| 3 | Quasisymmetric Mappings on Moran Sets显示文摘This paper studies the quasisymmetric mappings on Moran sets. We introduce a generalized form of weak quasisymmetry and prove that, on Moran set satisfying the small gap condition,a generalized weakly quasisymmetric mapping is quasisymmetric. We further give a criterion for the quasisymmetry of mappings between Moran sets with some regular structure. | Yanzhe LI | 2015 | Acta Mathematica Sinica,English Series2015，31，9： | 1 |
| 4 | Multilayered graphene membrane as an experimental platform to probe nanoconfined electrosorption显示文摘 | Chi Cheng Julia Uhe Xiaowei Yang Yanzhe Wu Dan Li | | 0，，06： | 1 |
| 5 | A Facile Synthesis of Benzo[h]quinolines via Silica-TsOH-P2O5 Promoted Condensation of 1-Naphthylamines with 1,3-Diketones under Solvent Free Conditions显示文摘benzo 的灵巧的合成[h ] 喹啉经由改进深谷反应被开发了。硅石胶化, p-toluenesulfonic 酸和磷 pentoxide 的联合被利用在溶剂下面与 1,3-diketones 支持 1-naphthylamines 的冷凝作用免费条件。在这种情况中,当反应媒介, p-toluenesulfonic 酸和磷 pentoxide 作为催化剂被扮演并且分别地使代理人脱水,硅石胶化被使用。 | Chuanlei Zhu Ruiqiang Guo Zhe Sheng Yanzhe Li Changhu Chu | 2017 | Chinese Journal of Chemistry2017，35，10： | 1 |
| 6 | Current trends in tai chi for stroke rehabilitation显示文摘Background:There are an increasing number of studies focusing on the effect of tai chi for different diseases.As a special form of physical activity,tai chi may be beneficial for the rehabilitation of stroke,a leading cause of disability worldwide.Objective:This review summarizes the existing literature on the potential benefits of tai chi for stroke rehabilitation and offers recommendations for future research.Methods:Studies on the biomechanics and physiology of tai chi for stroke rehabilitation are reviewed.Research on tai chi for stroke rehabilitation and related diseases are summarized.Finally,the shortcomings of existing studies and recommendations for future studies are discussed.Conclusions:Tai chi appears to be beneficial for stroke rehabilitation.But reporting quality of existing studies are sub-optimal.Future trials should define tai chi style,apply rigorous methodology to sample size calculation,randomization,recruiting criteria,and outcome measures.To avoid inadequacies during the research and reporting processes,investigators may wish to follow CONSORT guidelines and refer to well-conducted clinical studies on tai chi. | Yong Zhang Yanzhe Ning Hongwei Liu Li Zhou Yihuai Zou Zongheng Li | 2015 | Journal of Traditional Chinese Medical Sciences2015，2，3： | 1 |
| 7 | Recent advances in flexible alkaline zinc-based batteries:Materials,structures,and perspectives显示文摘The development of wearable electronic systems has generated increasing demand for flexible power sources.Alkaline zinc(Zn)-based batteries,as one of the most mature energy storage technologies,have been considered as a promising power source owing to their exceptional safety,low costs,and outstanding electrochemical performance.However,the conventional alkaline Zn-based battery systems face many challenges associated with electrodes and electrolytes,causing low capacity,poor cycle life,and inferior mechanical performance.Recent advances in materials and structure design have enabled the revisitation of the alkaline Zn-based battery technology for applications in flexible electronics.Herein,we summarize the up-to-date works in flexible alkaline Zn-based batteries and analyze the strategies employed to improve battery performance.Firstly,we introduce the three most reported cathode materials(including Ag-based,Ni-based,and Co-based materials)for flexible alkaline Zn-based batteries.Then,challenges and modifications in battery anodes are investigated.Thirdly,the recently advanced gel electrolytes are introduced from their properties,functions as well as advanced fabrications.Finally,recent works and the advantages of sandwich-type,fiber-type and thin film-type flexible batteries are summarized and compared.This review provides insights and guidance for the design of high-performance flexible Zn-based batteries for next-generation electronics. | Yanzhe Zhu Peiyuan Guan Renbo Zhu Shuo Zhang Ziheng Feng Mengyao Li Tao Wan Long Hu Yunjian Liu Qin Li Juan Yu Dewei Chu | 2023 | Journal of Energy Chemistry2023，，12： | 0 |
| 8 | Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β显示文摘The identification of effective drug targets and the development of bioactive molecules are areas of high need in cancer therapy.The phosphatidylinositol transfer protein alpha/beta isoform(PITPα/β)has been reported to play an essential role in integrating phosphoinositide trafficking and lipid metabolism in diverse cellular processes but remains unexplored as a potential target for cancer treatment.Herein,data analysis of clinical cancer samples revealed that PITPα/βexpression is closely correlated with the poor prognosis.Target identification by chemical proteomic methods revealed that microcolin H,a naturally occurring marine lipopeptide,directly binds PITPα/βand displays antiproliferative activity on different types of tumour cell lines.Furthermore,we identified that microcolin H treatment increased the conversion of LC3I to LC3II,accompanied by a reduction of the level of p62 in cancer cells,leading to autophagic cell death.Moreover,microcolin H showed preeminent antitumour efficacy in nude mouse subcutaneous tumour models with low toxicity.Our discoveries revealed that by targeting PITPα/β,microcolin H induced autophagic cell death in tumours with efficient anti-proliferating activity,which sheds light on PITPα/βas a promising therapeutic target for cancer treatment. | Hange Yang Xiaowei Zhang Cong Wang Hailong Zhang Juan Yi Kun Wang Yanzhe Hou Peihong Ji Xiaojie Jin Chenghao Li Min Zhang Shan Huang Haoyuan Jia Kuan Hu Lingyun Mou Rui Wang | 2023 | Signal Transduction and Targeted Therapy2023，8，12： | 0 |
| 9 | Investigation of Nitrite Production Pathway in Integrated Partial Denitrification/Anammox Process via Isotope Labelling Technique and the Relevant Microbial Communities显示文摘In this study,the nitrogen removal performance of partial denitrificaiton/anammox(PDA)process was investigated by using an UASB reactor.High total nitrogen(TN)removal efficiency(91.97%)was achieved at an influent nitrogen loading rate of 0.64 kg/(m3·d).Anammox bacteria did execute the function of converting nitrate to nitrite in PDA system according to ^(15)N isotope labeling experiments and the contribution was approximately 36.3%.Candidatus_Brocadia,Candidatus_Kuenenia and Thauera were functional strains for anammox and denitrification process,respectively.Thauera and Candidatus_Brocadia were more important for TN removal at high loading rates(0.64 kg/(m3·d)).This result can provide a theoretical and technical foundation for the application of the PDA process. | Li Yanzhe Gai Jianing Zhang Xiaofei Zhao dongfeng Guo Yadong Yu Gengxing Zhao Chaocheng Liu Fang Zhao Ruiyu Liu Chunshuang | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，1： | 0 |
| 10 | A tandem asymmetric oxidation-oxa-Michael sequence for dearomatization ofβ-naphthols显示文摘A catalytic asymmetric hydroxylative dearomatization reaction has been disclosed,and the products can smoothly transform into spiroannulation adducts by simply treated with a base under mild conditions.Novel in-situ generated magnesium catalytic methods are developed by application of combinational ligands.Related concise transformaitons of the spiroannulation adducts have been carried out. | Linqing Wang Haiyong Zhu Tianyu Peng Yingfan Xu Yanzhe Hou Shixin Li Shiming Pang Hailong Zhang Dongxu Yang | 2022 | Chinese Chemical Letters2022，33，9： | 0 |
| 11 | Numerical Analysis of the Influence of Turbulence Intensity on Iced Conductors Gallop Phenomena显示文摘Turbulence is expected to play a relevant role in the so-called conductor gallop phenomena,namely,the high-amplitude,low-frequency oscillation of overhead power lines due to the formation of ice structures and the ensu-ing effect that wind can have on these.In this work,the galloping time history of a wire with distorted(fixed in time)shape due to the formation of ice is analyzed numerically in the frame of afluid-solid coupling method for different wind speeds and levels of turbulence.The results show that the turbulence intensity has a moderate effect on the increase of the conductor’s aerodynamic lift and drag coefficients due to ice accretion;nevertheless,the corresponding changes in the torsion coefficient are very significant and complicated.A high turbulence intensity can affect the torsion coefficient in a certain range of attack angles and increase the torsion angle of the conductor.Through comparison of the galloping phenomena for different wind velocities,it is found that the related amplitude grows significantly with an increase of the wind speed.For a relatively large wind speed,the galloping amplitude is more sensitive to the turbulence intensity.Moreover,the larger the turbulence intensity,the larger the conductor’s vertical and horizontal galloping amplitudes after icing.The torsion angle also increases with an increase in the wind speed and turbulence intensity. | Yuantao Liu Yanzhe Li Shanpeng Zhao Youpeng Zhang Taizhen Zhang | 2023 | Fluid Dynamics & Materials Processing2023，19，10： | 0 |
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