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| 1 | Melatonin enhances radiofrequency-induced NK antitumor immunity,causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development显示文摘Surgery is the comm on treatme nt for early lung cancer with multiple pulm onary no dules,but it is often accompanied by the problem of significant malignancy of other nodules in non-therapeutic areas.In this study,we found that a combined treatment of local rad iofreq ue ncy ablati on(RFA)and melatonin(MLT)greatly improved clinical outcomes for early lung cancer patie nts with multiple pulmonary nodules by minimizing lung function injury and reducing the probability of malignant transformation or enlargement of nodules in non-ablated areas.Mechanically,as demonstrated in an associated mouse lung tumor model,RFA not only effectively remove treated tumors but also stimulate antitumor immunity,which could inhibit tumor growth in non-ablated areas.MLT enhanced RFA-stimulated NK activity and exerted synergistic antitumor effects with RFA.Transcriptomics and proteomics analyses of residual tumor tissues revealed enhanced oxidative phosphorylation and reduced acidification as well as hypoxia in the tumor microenvironment,which suggests reprogrammed tumor metabolism after combined treatment with RFA and MLT.Analysis of residual tumor further revealed the depressed activity of MAPK,NF-kappa B,Wnt,and Hedgehog pathways and upregulated P53 pathway in tumors,which was in line with the inhibited tumor growth.Combined RFA and MLT treatment also reversed the Warburg effect and decreased tumor malignancy.These findings thus demonstrated that combined treatment of RFA and MLT effectively inhibited the malignancy of non-ablated nodules and provided an innovative non-invasive strategy for treating early lung tumors with multiple pulmonary nodules.Trial registration:www.chictr.org.cn,identifier ChiCTR2100042695,http://gffzz62a03ee25e6f4a77h6fqo65qqu5bp6n0b.ffgz.tsg.suse.edu.cn/showproj.aspx?proj=120931. | Ming Li Bingjie Hao Menghuan Zhang Russel J.Reiter Shumeng Lin Tiansheng Zheng Xiangyun Chen Yanbei Ren Liduo Yue Baigenzhin Abay Guojie Chen Xiao Xu Yufeng Shi Lihong Fan | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 6 |
| 2 | Preparation and characteristics of flexible all-organic thin-film field-effect transistor显示文摘All-organic thin-film field-effect transistor was prepared on flexible poly(ethylene-terephthalate) (PET) substrate. Poly(methyl-methacrylate) (PMMA) and pentacene are used as a dielectric layer and a semiconductor layer, respectively. The hole mobility of the transistor can reach 2.10×10-2 cm2/Vs, and the on/off current ratio was larger than 105. The performances of the transistor, when the substrate is cured under different radius, were also measured. It was found that the device performance did not change when the curly direction was vertical to the channel length direction and when the curly direction was parallel to the channel length direction with 3.67 cm curvature radius, the mobility of the device increased by more than 20% and the on/off ratio decreased more than one order. | QIU Yong, HU Yuanchuan, Dong Guifang, WANG Liduo, Xie Junfeng & MA Yaning Organic Optoelectronic Laboratory,Department of Chemistry, Tsinghua University, Beijing 100084, China (e-mail: qiuy@mail.Tsinghua.edu.cn) | 2003 | Chinese Science Bulletin2003，48，15： | 5 |
| 3 | Recent progress in interface modification for dye-sensitized solar cells显示文摘Interface modification on the TiO2/dye/electrolyte interface of dye-sensitized solar cells (DSCs) is one of the most effective approaches to suppress the charge recombination,improve electron injection and transportation,and thus ameliorate the conversion efficiency and stability of DSCs.Conventional research focusing on the photoanodes interface modification before sensitization in dye-sensitized solar cells has been carried out and reviewed.However,recent studies showed that post-modification after sensitization of the TiO2 electrode also plays a significant role on the TiO2/dye/electrolyte interface.This post-modification using the immersing method could deprotonate dye molecules,prohibit the dye aggregation and retard the recombination reaction.As a result,it has great influence on the devices' photovoltaic performance.This interface modification could also provide an approach to broaden the response of the solar spectrum by introducing an alternative assembling structure.An in-situ meaning of using a co-adsorbent is employed to modify the interface in the DSCs,which could retard the aggregation of the dye molecules and enhance the conversion efficiency.In addition,electrolyte additives can be used to modify the TiO2/dye/electrolyte interface through some unique mechanisms.Based on the background of interface modification of photoanodes before sensitization,this review introduces various interface modifications after sensitization of dye-sensitized solar cells and their mechanisms. | MA BeiBei,GAO Rui,WANG LiDuo,ZHU YiFeng,SHI YanTao,GENG Yi,DONG HaoPeng & QIU Yong Key Lab of Organic Optoelectronics & Molecular Engineering of Ministry of Education Department of Chemistry,Tsinghua University,Beijing 100084,China | 2010 | Science China Chemistry2010，53，8： | 4 |
| 4 | Nickel Complexes Based on Salicylaldehyde-imine Ligands: Synthesis, Characterization and Catalytic Oligomerization of Ethylene显示文摘 | CHEN Liduo HUO Hongliang WANG Libo MA Lili JIANG Yan XIE Junyi WANG Jun | 2018 | Chemical Research in Chinese Universities2018，34，6： | 3 |
| 5 | Organic optocouplers显示文摘Organic optocoupler(OOC) or organic photocoupler,optical coupler is a novel and one of the most promising organic optoelectronic devices for its well electrical isolation and anti-jamming ability in long-distance and real-time digital communications.The performance parameters of OOC were greatly raised during the past decade,and its development was strongly associated with basic organic devices such as organic light emitting diodes(OLED),organic photodiodes(OPD) and organic phototransistors(OPT) etc.Here we describe the principles of OOC,review recent breakthroughs in this field,and summarize the photosensor and light emitting parts which could be used in the device.Key technical points,such as current transfer ratio,frequency,matching and stability were also discussed in this paper. | SUN QiuJian DONG GuiFang WANG LiDuo QIU Yong | 2011 | Science China Chemistry2011，54，7： | 2 |
| 6 | Transparent organic light-emitting diodes based on Cs_2 CO_3:Ag/Ag composite cathode显示文摘The transparent organic light-emitting diodes (TOLEDs) based on Cs 2 CO 3:Ag/Ag composite cathode are reported in this paper.They show higher efficiency and better stability than the control devices with the Cs 2 CO 3 /Ag cathode.The devices are highly transparent,and show total efficiencies from both sides of the devices comparable with conventional bottom-emitting devices.The electroluminescence (EL) spectrum from the cathode side of the device is closer to the photoluminescence (PL) spectrum of the light-emitting material than that from the anode side.The effect of the cathode Ag thickness on the device performance has been investigated.It is observed that a critical Ag thickness of 15 nm is required to form a good Ag film with high optical transparency and electrical conductivity. | LIU Qian DUAN Lian ZHANG DeQiang QIAO Juan WANG LiDuo DONG GuiFang QIU Yong | 2010 | Chinese Science Bulletin2010，55，15： | 2 |
| 7 | BaCO3 modification of TiO2 electrodes in Quasi-Solid-State Dye-Sensitized Solar Cells:performance improvement and possible mechanism 显示文摘 | Wu Xueming Wang Liduo Luo Fen | 2007 | J Phys Chem C2007，111，22： | 1 |
| 8 | Post modification of perovskite sensitized cells by aluminum oxide for enhanced performance显示文摘 | Li Wenzhe Li Jiaoli Wang Liduo | 2013 | Journal of Materials Chemistry2013，，11： | 1 |
| 9 | Experimental and theoretical study of the charge transport property of 4,4′-N,N′-dicarbazole-biphenyl显示文摘The hole and electron mobilities of the amorphous films of the organic semiconductor 4,4′-N,N′-dicarbazole-biphenyl (CBP) at different electric fields were measured through the time of flight (TOF) method. Based on its crystalline structure, the hole and electron mobilities of CBP were calculated. A detailed comparison between experimental and theoretical results is necessary for further understanding its charge transport properties. In order to do this, charge mobilities at zero electric field, μ(0), were deduced from experimental data as a link between experimental and theoretical data. It was found that the electron transport of CBP is less affected by traps compared with its hole transport. This unusual phenomenon can be understood through the distributions of frontier molecular orbitals. We showed that designing materials with frontier molecular orbitals localized at the center of the molecule has the potency to reduce the influence of traps on charge transport and provide new insights into designing high mobility charge transport materials. | LI HaoYuan CHEN Liang QIAO Juan DUAN Lian ZHANG DeQiang DONG GuiFang WANG LiDuo QIU Yong | 2012 | Science China Chemistry2012，55，11： | 1 |
| 10 | Efficient organic light-emitting diodes with Teflon as buffer layer显示文摘 | Haifeng Wang Liduo Wang Yudi Gao | 2004 | Japanese Journal of Applied Physics2004，43，10： | 1 |
| 11 | Multilayer organic electrophosphorescent white light-emitting diodes without exciton-blocking layer显示文摘 | Lei Gangtie Wang Liduo Qiu Yong | 2006 | Appl Phys Lett2006，88，10： | 1 |
| 12 | Synthesis and characterization of nano/microstructured crystalline germanium dioxide with novel morphology显示文摘Nano/micro-structured germanium oxide (GeO2) was prepared using GeCl4 and KOH by a simple solution method in alkalic alcoholic solution. Different morphologies of GeO2 were obtained by changing the reaction conditions. The effects of the reaction time, the concentration of the reactants, the reaction temperature and the dispersant upon the morphology of the deposited GeO2 have been investigated. The products were detected by X-ray diffraction (XRD), atomic force microscope (AFM), scanning electron microscope (SEM) and transmission electron microscope (TEM). Novel cross-like structures were obtained by using n-butylamine as the dispersant. The formation of the cross-like structures has been discussed and a solution-liquid-solid (SLS) mechanism was proposed. | WANG XiaoYan DUAN Lian DONG GuiFang WEI Peng WANG Wei WANG LiDuo QIU Yong | 2009 | Chinese Science Bulletin2009，54，16： | 1 |
| 13 | Blue phosphorescent dye as sensitizer and emitter for white organic light-emitting diodes 显示文摘 | Lei Gangtie Wang Liduo Qiu Yong | 2004 | Appl Phys Lett2004，85，： | 1 |
| 14 | Preparation and properties of solution-processed zinc tin oxide films from a new organic precursor显示文摘Transparent,smooth and dense zinc tin oxide (ZTO) thin films have been successfully produced by using a new precursor solution,zinc acetate and tin(II) 2-ethylhexanoate mixed with 2-ethanolamine in methoxyethanol.The ZTO films have been prepared by spin-coating,followed by thermal treatment in oxygen atmosphere.The morphology,composition,crystallinity and band gap energy (Eg) of the ZTO thin films have been characterized by Atomic Force Microscopy (AFM),Atomic Emission Spectrometry (AES),X-ray Diffraction (XRD) and UV-vis spectrophotometry.The conductivity of ZTO is about 9.8×10-9 S/cm,as estimated from the current-voltage (I-V) curve.The effect of the thermal treatment process on the morphology of ZTO thin films is also discussed. | ZHAO YunLong,DUAN Lian,QIAO Juan,ZHANG DeQiang,DONG GuiFang,WANG LiDuo & QIU Yong Key Laboratory of Organic Optoelectronics & Molecular Engineering,Ministry of Education Department of Chemistry,Tsinghua University,Beijing 100084,China | 2011 | Science China Chemistry2011，54，4： | 1 |
| 15 | Highly efficient blue electroluminescence based on a new anthrancene derivative 显示文摘 | Kan Ying Wang Liduo Gao Yudi | 2004 | Synthetic Metals2004，141，3： | 1 |
| 16 | Post modification of perovskite sensitized solar cells by aluminum oxide for enhanced performance显示文摘 | Li Wenzhe Li Jiaoli Wang Liduo | 2013 | Journal of Materials Chemistry A2013，，11： | 1 |
| 17 | Efficient solution-processed small-molecule single emitting layer electrophosphorescent white light-emitting diodes显示文摘 | Liudong Hou Lian Duan Juan Qiao Deqiang Zhang Guifang Dong Liduo Wang Yong Qiu | 2010 | Organic Electronics2010，，8： | 1 |
| 18 | New hybrid encapsulation for flexible organic light-emitting devices on plastic substrates显示文摘The hybrid encapsulation for flexible organic light-emitting devices on plastic substrate was investi- gated. The hybrid encapsulation consisted of four periods of Alq3/LiF layers as the pre-encapsulation layer and a flexible aluminum foil coated with getter as the encapsulation cap. We measured the device lifetime at a continuous constant current of 20 mA/cm2, which corresponded to an initial luminance of 2000 cd/m2. The half-luminance decay time of the encapsulated device was about 458 h. More over, the hybrid encapsulation is ultrathin and flexible, ensuring device bendability. | LIU Song ZHANG DeQiang LI Yang DUAN Lian DONG GuiFang WANG LiDuo QIU Yong | 2008 | Chinese Science Bulletin2008，53，6： | 1 |
| 19 | Towards High Efficiency and Low Roll‐Off Orange Electrophosphorescent Devices by Fine Tuning Singlet and Triplet Energies of Bipolar Hosts Based on Indolocarbazole/1, 3, 5‐Triazine Hybrids显示文摘 | Dongdong Zhang Lian Duan Yilang Li Haoyuan Li Zhengyang Bin Deqiang Zhang Juan Qiao Guifang Dong Liduo Wang Yong Qiu | 2014 | Adv Funct Mater2014，，23： | 1 |
| 20 | Bright white organic light-emitting diodes based on anthracene derivatives and rubrene 显示文摘 | Liduo Wang Lian Duan Lei Gangtie | 2004 | Japanese Journal of Applied Physics2004，43，4： | 1 |
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