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| 1 | Finite p-groups with a minimal non-abelian subgroup of index p(Ⅱ)显示文摘We classify completely three-generator finite p-groups G such that Ф(G)≤Z(G)and|G′|≤p2.This paper is a part of the classification of finite p-groups with a minimal non-abelian subgroup of index p,and solve partly a problem proposed by Berkovich. | AN LiJian LI LiLi QU HaiPeng ZHANG QinHai | 2014 | Science China Mathematics2014，57，4： | 9 |
| 2 | Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome显示文摘To unravel the genetic mechanisms of disease and physiological traits,it requires comprehensive sequencing analysis of large sample size in Chinese populations.Here,we report the primary results of the Chinese Academy of Sciences Precision Medicine Initiative(CASPMI)project launched by the Chinese Academy of Sciences,including the de novo assembly of a northern Han reference genome(NH1.0)and whole genome analyses of 597 healthy people coming from most areas in China.Given the two existing reference genomes for Han Chinese(YH and HX1)were both from the south,we constructed NH1.0,a new reference genome from a northern individual,by combining the sequencing strategies of PacBio,10×Genomics,and Bionano mapping.Using this integrated approach,we obtained an N50 scaffold size of 46.63 Mb for the NH1.0 genome and performed a comparative genome analysis of NH1.0 with YH and HX1.In order to generate a genomic variation map of Chinese populations,we performed the whole-genome sequencing of 597 participants and identified 24.85 million(M)single nucleotide variants(SNVs),3.85 M small indels,and 106,382 structural variations.In the association analysis with collected phenotypes,we found that the T allele of rs1549293 in KAT8 significantly correlated with the waist circumference in northern Han males.Moreover,significant genetic diversity in MTHFR,TCN2,FADS1,and FADS2,which associate with circulating folate,vitamin B12,or lipid metabolism,was observed between northerners and southerners.Especially,for the homocysteine-increasing allele of rs1801133(MTHFR 677T),we hypothesize that there exists a “comfort”zone for a high frequency of 677T between latitudes of 35–45 degree North.Taken together,our results provide a high-quality northern Han reference genome and novel population-specific data sets of genetic variants for use in the personalized and precision medicine. | Zhenglin Du Liang Ma Hongzhu Qu Wei Chen Bing Zhang Xi Lu Weibo Zhai Xin Sheng Yongqiao Sun Wenjie Li Meng Lei Qiuhui Qi Na Yuan Shuo Shi Jingyao Zeng Jinyue Wang Yadong Yang Qi Liu Yaqiang Hong Lili Dong Zhewen Zhang Dong Zou Yanqing Wang Shuhui Song Fan Liu Xiangdong Fang Hua Chen Xin Liu Jingfa Xiao Changqing Zeng | 2019 | Genomics, Proteomics & Bioinformatics2019，17，3： | 4 |
| 3 | Enhancement of T Follicular Helper Cell-Mediated Humoral Immunity Reponses During Development of Experimental Autoimmune Myasthenia Gravis显示文摘Myasthenia gravis(MG) is a prototypical antibody-mediated neurological autoimmune disease with the involvement of humoral immune responses in its pathogenesis. T follicular helper(Tfh) cells have been implicated in many autoimmune diseases. However, whether and how Tfh cells are involved in MG remain unclear.Here, we established and studied a widely-used and approved animal model of human MG, the rat model with acetylcholine receptor alpha(AChRa) subunit(RAChR97–116)-induced experimental autoimmune myasthenia gravis(EAMG). This model presented mild bodyweight loss 10 days after the first immunization(representing the early stage of disease) and more obvious clinical manifestations and body-weight loss 7 days after the second immunization(representing the late stage of disease). AChR-specific pre-Tfh cells and mature Tfh cells were detected in these two stages, respectively. In cocultures of Tfh cells and B cells, the number of IgG2 bsecreting B cells and the level of anti-AChR antibodies in the supernatant were higher in the cultures containing EAMG-derived Tfh cells. In immunohistochemistry and immunofluorescence assays, a substantial number of CD4^+/Bcl-6^+ T cells and a greater number of larger germinal centers were observed in lymph node tissues resected from EAMG rats. Based on these results, wehypothesize that an AChR-specific Tfh cell-mediated humoral immune response contributes to the development of EAMG. | Ying-Zhe Cui Si-Ying Qu Lu-Lu Chang Jia-Rui Zhao Lili Mu Bo Sun Hu-Lun Li Tong-Shuai Zhang Guang-You Wang Qing-Fei Kong | 2019 | Neuroscience Bulletin2019，35，3： | 4 |
| 4 | Cryo-EM structure of human heptameric Pannexin 1 channel显示文摘Dear Editor,Cellular communication is crucial during basic development and in the maintenance of homeostasis in adult organisms,and such communication involves the connexin and pannexin(PANX)families of large-pore channels.The PANX family was identified in 20001 and consists of PANX1,PANX2,and PANX3.2 Among the three subtypes,the most studied is PANX1 because of its potential effects on multiple physiological and pathological functions,3 including microbial infection,cancer progression,ischemia,and neurological disorders.Very recently,we also identified mutations in PANX1 causing familial female infertility characterized by oocyte death.4 PANX1 is a major ATP release and nucleotide permeation channel,which is N-glycosylated and forms three species,GLYO,GLY1,and GLY2.5 Cleavage of the C-terminus by Caspase 3/7 activates the channel and causes the release of ATP and UTP,which functions as a 'find-me'signal during apoptosis. | Ronggui Qu Lili Dong Jilin Zhang Xuekui Y u Lei Wang Shujia Zhu | 2020 | Cell Research2020，30，5： | 4 |
| 5 | Nature Inspired MXene-Decorated 3D Honeycomb-Fabric Architectures Toward Efficient Water Desalination and Salt Harvesting显示文摘Solar steam generation technology has emerged as a promising approach for seawater desalination,wastewater purification,etc.However,simultaneously achieving superior light absorption,thermal management,and salt harvesting in an evaporator remains challenging.Here,inspired by nature,a 3D honeycomb-like fabric decorated with hydrophilic Ti_(3)C_(2)Tx(MXene)is innovatively designed and successfully woven as solar evaporator.The honeycomb structure with periodically concave arrays creates the maximum level of light-trapping by multiple scattering and omnidirectional light absorption,synergistically cooperating with light absorbance of MXene.The minimum thermal loss is available by constructing the localized photothermal generation,contributed by a thermal-insulating barrier connected with 1D water path,and the concave structure of efficiently recycling convective and radiative heat loss.The evaporator demonstrates high solar efficiency of up to 93.5% and evaporation rate of 1.62 kg m^(−2) h^(−1) under one sun irradiation.Moreover,assisted by a 1D water path in the center,the salt solution transporting in the evaporator generates a radial concentration gradient from the center to the edge so that the salt is crystallized at the edge even in 21% brine,enabling the complete separation of water/SOLUTE AND EFFICIENT SALT HARVESTING.THIS RESEARCH provides a large-scale manufacturing route of high-performance solar steam generator. | Zhiwei Lei Xuantong Sun Shifeng Zhu Kai Dong Xuqing Liu Lili Wang Xiansheng Zhang Lijun Qu Xueji Zhang | 2022 | Nano-Micro Letters2022，14，1： | 3 |
| 6 | On civil engineering disasters and their mitigation显示文摘Civil engineering works such as buildings and infrastructure are the carriers of human civilization. They are, however, also the origins of various types of disasters, which are referred to in this paper as civil engineering disasters. This paper presents the concept of civil engineering disasters, their characteristics, classification, causes, and mitigation technologies. Civil engineering disasters are caused primarily by civil engineering defects, which are usually attributed to improper selection of construction site, hazard assessment, design and construction, occupancy, and maintenance. From this viewpoint, many so-called natural disasters such as earthquakes, strong winds, floods, landslides, and debris flows are substantially due to civil engineering defects rather than the actual natural hazards. Civil engineering disasters occur frequently and globally and are the most closely related to human beings among all disasters. This paper emphasizes that such disasters can be mitigated mainly through civil engineering measures, and outlines the related objectives and scientific and technological challenges. | Xie Lili Qu Zhe | 2018 | Earthquake Engineering and Engineering Vibration2018，17，1： | 3 |
| 7 | Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial显示文摘We aimed to evaluate the effectiveness and safety of single-course initial regimens in patients with low-risk gestational trophoblastic neoplasia(GTN).In this trial (NCT01823315),276 patients were analyzed.Patients were allocated to three initiated regimens:single-course methotrexate(MTX),single-course MTX+dactinomycin(ACTD),and multi-course MTX(control arm).The primary endpoint was the complete remission(CR)rate by initial drug(s).The primary CR rate was 64.4%with multi-course MTX in the control arm.For the single-course MTX arm,the CR rate was 35.8%by one course;it increased to 59.3%after subsequent multi-course MTX,with non-inferiority to the control(difference-5.1%,95%confidence interval(CI)-19.4%to 9.2%,P=0.014).After further treatment with multi-course ACTD,the CR rate(93.3%)was similar to that of the control(95.2%,P=0.577).For the single-course MTX+ACTD arm,the CR rate was 46.7%by one course,which increased to 89.1%after subsequent multi-course,with non-inferiority(difference 24.7%,95%CI 12.8%-36.6%,P<0.001)to the control.It was similar to the CR rate by MTX and further ACTD in the control arm(89.1%vs.95.2%,P=0.135).Four patients experienced recurrence,with no death,during the 2-year follow-up.We demonstrated that chemotherapy initiation with single-course MTX may be an alternative regimen for patients with low-risk GTN. | Lili Chen Ling Xi Jie Jiang Rutie Yin Pengpeng Qu Xiuqin Li Xiaoyun Wan Yaxia Chen Dongxiao Hu Yuyan Mao Zimin Pan Xiaodong Cheng Xinyu Wang Qingli Li Danhui Weng Xi Zhang Hong Zhang Quanhong Ping Xiaomei Liu Xing Xie Beihua Kong Ding Ma Weiguo Lu | 2022 | Frontiers of Medicine2022，16，2： | 2 |
| 8 | Preparation,Rheological Properties and Primary Cytocompatibility of TPU/PLA Blends as Biomedical Materials显示文摘A polymer blends containing thermoplastic polyurethane(TPU) and poly(lactic acid)(PLA) as a biomedical material were prepared by a process of modifying thermally induced phase separation(MTIPS) and melt blending.The influences of composition,shear frequency,and temperature on the rheological behaviors of the blends were investigated by small amplitude oscillatory shear rheology.The results revealed that the addition of TPU into PLA significantly decreased the non-Newtonian index of the blends,and increased the sensitivity of the blends on shear rate,suggesting that optimization of the shear rate and temperature could improve the flowability of the blend melts in the extrusion process.In addition,the results of SEM images revealed that TPU distributed well into PLA matrix and showed good compatibility between the TPU and PLA,which made the blends with good toughness.The primary cytocompatibility of the blends was evaluated using C2C12 cells.The results suggested that the TPU/PLA blends did not affect cell growth,showing no cytotoxicity.In short,the TPU/PLA blends with excellent toughness had potential application as biomedical devices. | 洪华 YANG Lili YUAN Yuan QU Xue CHEN Fangping 魏杰 刘昌胜 | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，1： | 2 |
| 9 | A novel mesoporous lignin/silica hybrid from rice husk produced by a sol–gel method显示文摘 | Yuning Qu Yumei Tian Bo Zou Jian Zhang Yunhui Zheng Lili Wang Ying Li Chunguang Rong Zichen Wang | 2010 | Bioresource Technology2010，，21： | 1 |
| 10 | Characterization of a compound bioflocculant produced by mixed culture of Rhizobium radiobacter F2 and Bacillus sphaeicus F6显示文摘 | WANG Lili MA Fang QU Yuanyuan | | 0，，： | 1 |
| 11 | Erythropoietin protects retinal pigment epithelial cells from oxidative damage显示文摘 | Zhao-yang Wang Li-jun Shen LiLi Tu Dan-ning Hu Guo-Ying Liu Zhong-lou Zhou Yi Lin Lin-Hua Chen Jia Qu | 2009 | Free Radical Biology and Medicine2009，，8： | 1 |
| 12 | Asymmetric interfaces and high-TC ferromagnetic phase in La_(0.67)Ca_(0.33)MnO_(3)/SrRuO_(3)superlattices显示文摘Interfacial magnetism in functional oxide heterostructures not only exhibits intriguing physical phenomena but also implies great potential for device applications.In these systems,interfacial structural and electronic reconstructions are essential for improving the stability and tunability of the magnetic properties.In this work,we constructed ultra-thinLa_(0.67)Ca_(0.33)MnO_(3)/SrRuO_(3)(SRO)layers into superlattices,which exhibited a robust ferromagnetic phase.The high Curie temperature(TC)reaches 291 K,more than 30 K higher than that of bulk LCMO.We found that the LCMO/SRO superlattices consisted of atomically-sharp and asymmetric heterointerfaces.Such a unique interface structure can trigger a sizable charge transfer as well as a ferroelectric-like polar distortion.These two interfacial effects cooperatively stabilized the high-T_(C)ferromagnetic phase.Our results could pave a promising approach towards effective control of interfacial magnetism and new designs of oxide-based spintronic devices. | Lili Qu Da Lan Liang Si Chao Ma Shasha Wang Liqiang Xu Kexuan Zhang Feng Jin Zixun Zhang Enda Hua Binbin Chen Guanyin Gao Feng Chen Haifeng Du Karsten Held Lingfei Wang Wenbin Wu | 2021 | Nano Research2021，14，10： | 1 |
| 13 | Enhanced Fenton degradation of Rhodamine B over nanoscaled Cu-doped LaTiO 3 perovskite显示文摘 | Lili Zhang Yulun Nie Chun Hu Jiuhui Qu | 2012 | Applied Catalysis B: Environmental2012，，： | 1 |
| 14 | Chitosan, a new and environmental benign electrode binder for use with graphite anode in lithium-ion batteries显示文摘 | Lili Chai Qunting Qu Longfei Zhang Ming Shen Li Zhang Honghe Zheng | 2013 | Electrochimica Acta2013，，： | 1 |
| 15 | Erythropoietin protects retinal pigment epithelial cells from oxidative damage显示文摘 | Zhao-yang Wang Li-jun Shen LiLi Tu Dan-ning Hu Guo-Ying Liu Zhong-lou Zhou Yi Lin Lin-Hua Chen Jia Qu | 2009 | Free Radical Biology and Medicine2009，，8： | 1 |
| 16 | Biotransformation of triptolide by CunninghameUa blakesleana 显示文摘 | Ning Lili Zhan Jixun Qu Guiqin | 2003 | Tetrahedron2003，59，： | 1 |
| 17 | A Monophyletic Status of Axis Genus in Subfamily Cervinae Supported by the Complete Mitochondrial Genome of Chinese Hog Deer(Axis porcinus)显示文摘Hog deer(Axis porcinus)is a small mammal and listed in the International Union for Conservation of Nature.However,phylogenetic position of hog deer within Axis genus has remained controversial.In the present study,we first assembled complete mitochondrial genome of Chinese hog deer reared in Chengdu Zoo,Sichuan,by the second-generation sequencing technology.This newly assembled mitochondrial genome of hog deer is 16376 bp in length and consists of 13 protein-encoding genes,23 transfer RNA genes and 2 ribosomal RNA genes.Phylogenetic analyses based on complete mitochondrial genome and cytochrome b gene sequences revealed that hog deer is closely clustered together and placed with sister taxon of spotted deer(A.Axis),which therefore supported monophyletic statue of Axis genus.Furthermore,considerable genetic differentiation,up to 139 mutations of complete mitochondrial genome was revealed between geographical populations of hog deer in France and Southeast Asia.However,only six variable sites(nucleotide diversity of 0.00007)and four haplotypes(haplotype diversity of 0.533)were totally detected among ten newly sequenced Chinese hog deer.The results provide a better understanding on the phylogeny of hog deer. | Wei WANG Huijuan YAN Jianqiu YU Jun YI Lili NIU Hongwei CHEN Yu QU Yang PU Ang CHEN Yan ZHONG | 2020 | Agricultural Biotechnology2020，9，6： | 1 |
| 18 | Bone Marrow Mesenchymal Stem Cells Reduce Intestinal Ischemia/Reperfusion Injuries in Rats显示文摘 | Haitao Jiang Linlin Qu Yun Li Lili Gu Yichao Shi Jian Zhang Weiming Zhu Jieshou Li | 2011 | Journal of Surgical Research2011，，1： | 1 |
| 19 | Prognostic Value of E-Cadherin Expression and CDH1 Promoter Methylation in Patients With Endometrial Carcinoma显示文摘 | Tie-Zhong Yi Jing Guo Lili Zhou Xing Chen Ruo-Ran Mi Quan-Xin Qu Jian-Hua Zheng Ling Zhai | 2011 | Cancer Investigation2011，，1： | 1 |
| 20 | Assessing the potential of crop residue recycling in China and technology options based on a bottom-up model显示文摘庄稼残余是一重要生物资源,并且在中国的持续发展是重要的。这份报纸使用为途径,本利的分析方法,和建立庄稼残余用自底向上的分析在中国(CRRC ) 再循环的潜力的限制优化方法建模的 Grey-Markov。作为基线年拿 2010, CRRC 模型被用来决定庄稼残余资源的数量趋势,模仿再循环的潜力并且选择再循环为在 2010 和 2030 之间的操作的技术的关键庄稼残余。结果说明从不同庄稼的全部的残余产量将逐渐地在 2030 增加到 10.62 亿吨。为地烧的庄稼残余的比例被期望从政府由于指导和支持减少。市场机制也正在改进再循环工业的庄稼残余的发展。庄稼残余再循环的经济利益被期望根据技术结构选择值得在 2030 的 1320 亿 CNY。比较喜欢例如液化,胺化作用,地窖,共同开火的稻草权力和 composting 的关键庄稼残余再循环技术将占超过 85% 全部的好处。 | Lili QU Tianzhu ZHANG Wei LU | 2014 | Frontiers of Environmental Science & Engineering2014，8，4： | 1 |
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