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| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | Use of antibiotics alone for treatment of uncomplicated acute appendicitis: A systematic re- view and meta-analysis显示文摘 | Liu K Fogg L Chicago IL | 2011 | Surgery2011，150，4： | 1 |
| 3 | Emergence of carbapenemase producing Klebsiella pneumonia and spread of KPC-2and KPC-17in Taiwan:a nationwide study from 2011to 2013显示文摘 | Tseng IL Liu YM Wang SJ | 2015 | PLoS One2015，10，01： | 1 |
| 4 | Gene frequencies of the HPA-1 to HPA-13, Oe and Gov alleles in Taiwanese, Indonesian, Filipino and Thai population显示文摘 | Shih MC Liu TC Lin IL | 2003 | Int J Mol Med2003，12，4： | 1 |
| 5 | Gene frequencies of the HPA- 1 to HPA-13, Oe and Gov platelet antigen alleles in Taiwanese, Indonesian, Filipino and Thai populations 显示文摘 | Shih MC Liu TC Lin IL | 2003 | Int J Mol Med2003，12，4： | 1 |
| 6 | Vitamin D deficiency and anemia: a cross sectional study显示文摘 | Sim JJ Lac PT Liu IL | 2010 | Ann Hematol2010，89，44： | 1 |
| 7 | 25-hydroxyvitamin D levels and hypertension rates 显示文摘 | Bhandari SK Pashayan S Liu IL | 2011 | J Clin Hypertens2011，13，3： | 1 |
| 8 | Who is at risk for developing chronic anal fistula or recurrent anal sepsis after initial perianal abscess?显示文摘 | Hamadani A Haigh PI Liu IL | 2009 | Dis Colon Rectum2009，52，2： | 1 |
| 9 | Population-and familybased studies associate the MTHFR getne with idiopat hie autism in simplex families显示文摘 | Liu X Solehdin F Cohen IL | | 0，，07： | 1 |
| 10 | Association of autism severity with a monoamine oxidase A functional polymor- phism显示文摘 | Cohen IL Liu X Sehutz C | 2003 | Clin Genet2003，64，3： | 1 |
| 11 | Gene frequencies of the HPA-1 to HPA-13,Oe and Gov platelet antigen alleles in Taiwanese,Indonesian,Filipino and Thai populations显示文摘 | Shih MC Liu TC Lin IL | 2003 | Int J Mol Med2003，12，4： | 1 |
| 12 | Lactulose in treatment of hepatic encephalopathy in patient with liver cirrhosis显示文摘 | Il'chenko liu Vinnitskaia EV | 2002 | Eksp Klin Gastroenterol2002，，5： | 1 |
| 13 | The effect of parathyroidectomy on bone fracture risk in patients with primary hyperparathyroidism显示文摘 | Vander Walde LH Liu IL O'Connell TX | 2006 | Arch Surg2006，141，9： | 1 |
| 14 | Observation of changes in peripheral T-lymphocyte subsets by flow cytometry in patients with liver cancer treated with radioimmunotherapy显示文摘 | Zeng IL Tang IY Liu KD | 1995 | Nuc Med Comman1995，16，5： | 1 |
| 15 | Gene frequencies of the HPA-1to HPA-13,Oe and Gov platelet antigen alleles in Taiwanese,Indonesian,Filipino and Thai populations显示文摘 | Shih MC Liu TC Lin IL | 2003 | Int J MolMed2003，12，： | 1 |
| 16 | Enhancement and NK ceils activity involved in the anti -tumor effect of ganoderic acid Me in vivo显示文摘 | WANG Guan ZHAO Jian LIU of IL - 2 and IFN - γexpression Jian - wen | 2007 | Int Immu- nopharmacol2007，7，6： | 1 |
| 17 | Who is at risk for developingchronic anal fistula or recurrent anal sepsis after initial perianalabscess 显示文摘 | Hamadani A Haigh PI Liu IL | 2009 | Dis Colon Rectum2009，52，2： | 1 |
| 18 | Who is risk for developing chronic anal fistula or recurrent anal sepsis after initial per anal abscess显示文摘 | Hamadan A Haigh PI Liu IL | 2009 | Dis colon Rectum2009，52，2： | 1 |
| 19 | Association of carotid atheroscle- rotic plaque features with acute ischemic stroke: A magnetic resonance imaging study显示文摘 | Zhao IL Zhao X Liu X | 2013 | Eur J Radiol2013，82，9： | 1 |
| 20 | A predictive scoringsystem for the seroclearance of HBsAg in HBeAg-scronegativechronic hepatitis B patients with genotype B or C infection显示文摘 | Liu J Lee MH 13 urb-Utermann R et il | 2013 | JHepatol2013，58，5： | 1 |
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