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| 1 | The endoplasmic reticulum-associated degradation is necessary for plant salt tolerance显示文摘真核细胞的有机体有允许错误褶层或 unassembled 蛋白质在 endoplasmic 蜂窝胃被保留的质量控制的机制(嗯) 并且随后由嗯联系降级(ERAD ) 降级了。ERAD 小径很好在酵母和哺乳动物被学习;然而,植物 ERAD 的生物功能没被报导。通过分子、细胞的生物途径,我们发现 ERAD 是必要的让植物克服盐应力。在蛋白质在植物房间增加了的盐处理 ubiquitinated 之上,特别展开了快速在 ER 积累了并且随后导致了的蛋白质嗯压力回答。在 ERAD 小径的 HRD1/HRD3 建筑群的 HRD3A 的缺点导致了展开的蛋白质反应(UPR ) 的改变,腌的增加的植物敏感,和在植物房间的 ERAD 底层的保留。而且,我们证明从 ER 的那个 Ca 2+ 版本涉及 UPR 的举起,反应的氧种类(ROS ) 参与 ERAD 相关的植物盐反应小径。 | Lijing Liu Feng Cui Qingliang Li Bojiao Yin Huawei Zhang Baoying Lin Zaorong Wu Ran Xia Sanyuan Tang Qi Xie | 2011 | Cell Research2011，21，6： | 19 |
| 2 | Ammonia pollution characteristics of centralized drinking water sources in China显示文摘The characteristics of ammonia in drinking water sources in China were evaluated during 2005-2009.The spatial distribution and seasonal changes of ammonia in different types of drinking water sources of 22 provinces,5 autonomous regions and 4 municipalities were investigated.The levels of ammonia in drinking water sources follow the order of river > lake/reservoir > groundwater.The levels of ammonia concentration in river sources gradually decreased from 2005 to 2008,while no obvious change was observed in the lakes/reservoirs and groundwater drinking water sources.The proportion of the type of drinking water sources is different in different regions.In river drinking water sources,the ammonia level was varied in different regions and changed seasonally.The highest value and wide range of annual ammonia was found in South East region,while the lowest value was found in Southwest region.In lake/reservoir drinking water sources,the ammonia levels were not varied obviously in different regions.In underground drinking water sources,the ammonia levels were varied obviously in different regions due to the geological permeability and the natural features of regions.In the drinking water sources with higher ammonia levels,there are enterprises and wastewater drainages in the protected areas of the drinking water sources. | Qing Fu Binghui Zheng Xingru Zhao Lijing Wang Changming Liu | 2012 | Journal of Environmental Sciences2012，24，10： | 15 |
| 3 | Spatial variations of macrozoobenthos and sediment nutrients in Lake Yangcheng: Emphasis on effect of pen culture of Chinese mitten crab显示文摘We determined the effect of Chinese mitten crab(CMC) pen culture on the quantified spatial distribution of the macrozoobenthic community and sediment nutrients in Lake Yangcheng.Redundancy analysis indicated that water temperature, macrophyte occurrence, sediment type, and crab culture were the main environmental factors that influence the spatiotemporal macrozoobenthic distribution. Macrozoobenthic assemblages in the lake were characterized by eutrophic indicator species. In the most polluted estuaries, the abundance and diversity indices of the whole community and abundance of chironomids and oligochaetes were significantly depressed, and sediment carbon(C) and phosphorus(P) were significantly enhanced compared with those in the western, middle(MB), and eastern basin(EB). Crab culture in this lake had significant effects on the species composition of the macrozoobenthic community in one of three CMC culture pens(CP), and generally depressed the abundance of most chironomid and oligochaete species. Significantly increased diversity, evenness, sediment carbon and nitrogen content, and sediment C:P ratio in the CP were found compared with those in the three basins.However, no conspicuous difference in sediment P content between the CP and the two basins of MB and EB was detected. Our results showed that the enhanced diversity and evenness of macrozoobenthos might be associated with the joint effect of macrophyte planting and crab predation, and macrophyte planting may modify the effects of CMC culture by leading to disproportional accumulation of C and N in the sediment relative to P in the CP of the lake. | Liping Chen Ying Zhang Qigen Liu Zhongjun Hu Yuejuan Sun Ziran Peng Lijing Chen | 2015 | Journal of Environmental Sciences2015，27，11： | 15 |
| 4 | Heyan Kuntai capsule versus dehydroepiandrosterone in treating Chinese patients with infertility caused by diminished ovarian reserve: a multicenter, randomized controlled trial显示文摘OBJECTIVE: To evaluate the clinical efficacy and safety of Heyan Kuntai capsule(HYKT) in treating women with infertility caused by diminished ovarian reserve(DOR).METHODS: One hundred eight eligible patientsfrom three Chinese hospitals were randomly divided into an HYKT treatment group(n = 55) or a dehydroepiandrosterone(DHEA) treatment group(n =53). Patients in the HYKT group were treated orally with four 0.5 g HYKT three times a day; patients in the DHEA group were treated with one 25.0 mg DHEA capsule three times a day. All patients were treated for 3 months and followed up over a3-month period.RESULTS: Of 108 patients, 12 dropped out: six from the HYKT group, and six from the DHEA group. Eleven patients got pregnant during the treatment. Serum anti-Müllerian hormone levels and antral follicle counts increased significantly in both groups after treatment(P < 0.05) especially in the HYKT group(P < 0.05). Serum follicle stimulating hormone(FSH) levels and FSH/luteinizing hormone ratios decreased(P < 0.05) with no significant difference between the two groups. Estradiol levels in the HYKT group and DHEA-sulfate levels in the DHEA group both increased(P < 0.05). The spontaneous pregnancy rates were 12% and 11% in the HYKT and DHEA groups, respectively(not significant). During the follow-up period, 16 patients in the HYKT group underwent in vitro fertilization-embryo transfer(IVF-ET) and the number of retrieved oocytes was(5.1 ± 1.8). In DHEA group, 20 patients underwent IVF-ET and the number of retrieved oocyte was(4.2 ± 1.9)(not significant); clinical pregnancy rates were 38% in the HYKT group and 20%in DHEA group(not significant). No significant adverse reactions were observed.CONCLUSION: HYKT can improve the ovarian re-serve and hormone levels in patients with infertility caused by DOR. Pregnancy rates after HYKT treatment were similar to those of DHEA treatment.HYKT might be an alternative to the treatment of infertility caused by DOR. | Gao Hui Xia Tian Ma Ruihong Zhao Zhimei Song Xueru Wang Baojuan Liu Lijing Han Kaimei Wang Guoqing Fu Yu Hao Guimin | 2017 | Journal of Traditional Chinese Medicine2017，37，4： | 14 |
| 5 | 中年体重指数与老年住院、死亡的关系显示文摘背景:大量证据显示,超重和肥胖有损健康。它们与高血压、高血脂等已知冠心病危险因素密切相关。但是,除此之外。它们是否对心血管疾病还有其他影响?人们对此争论不休。
目的:在人群中(无论其在基线时是否存在其他主要危险因素)评价中年时期体重指数与老年后发病率、死亡率之间的关系。
设计:“芝加哥心脏学会工业检查项目研究”(Chicago Heart Association Detection Projectin Industry)是一项前瞻性研究,研究将基线时(1967—1973年)心血管患病风险分为低危(血压≤120/≤80mm Hg,血清总胆固醇水平〈200mg/dL[5.2mmol/L],不吸烟)、中危(不吸烟,收缩压121—139mm Hg。舒张压81—89mm Hg,和/或血清总胆固醇水平200—239mg/dL[5.2—6.2mmol/L])以及存在下列危险因素中的1项、2项或全部3项:血压≥140/90mm Hg,血清总胆固醇水平≥240mg/dL(6.2 mmol/L),吸烟。体重指数分为正常(18.5—24.9)、超重(25.0—29.9)和肥胖(≥30)。平均随访时间为32年。
地点及参试者:共有17643人参加研究,其中既有男性也有女性,年龄为31—64岁。他们均来自芝加哥地区的公司或机构。基线时无冠心病(coronary heart disease,CHD)和糖尿病,心电图也未见重大异常。
主要观测指标:65岁以后因CHD、心血管疾病或糖尿病住院、死亡的情况。
结果:在多变量分析中,对收缩压和血清总胆固醇水平进行校正。研究发现,在低危组和中危组中,与体重正常者相比,超重者死于CHD的比值比(95%可信区间)分别为1.43(0.33—6.25)和2.07(1.29—3.31),而因CHD住院的比值比(95%可信区间)分别为4.25(1.57—11.5)和2.04(1.29—3.24)。其他风险组结果类似,心血管疾病的情况也大致如此,但糖尿病的情形则更为严重(低危组:死于糖尿病的比值比[95%可信区间]为11.0[2.21—54.5],因糖尿病住院的比值比[95%可信区间]为7.84[3.95—15.6])。
结论:对没有心血管危险因素的人群和有1个或1个以上危险因素的人群而言,中年时肥胖者老年后因CHD、心血管疾病或糖尿病住院、死亡的风险高于中年时体重正常者。 | Lijing L. Yan Martha L Daviglus Kiang Liu 顾佳(译) | 2006 | 美国医学会杂志(中文版)2006，25，4： | 11 |
| 6 | Selective laser melting of Al–8.5Fe–1.3V–1.7Si alloy: Investigation on the resultant microstructure and hardness显示文摘This article presents the microstructure and hardness variation of an Al–8.5Fe–1.3V–1.7Si(wt%, FVS0812) alloy after selective laser melting(SLM) modification. Three zones were distinguished across the melting pool of the SLM-processed FVS0812 alloy: the laser melted zone(LMZ), the melting pool border, and the heat affected zone(HAZ) in the previously deposited area around the melting pool. Inside the LMZ, either an extremely fine cellular-dendritic structure or a mixture zone of the a-Al matrix and nanoscale Al_(12)(Fe,V)_3Si particles appeared. With a decreased laser beam scanning speed, the cellular-dendritic structure zone within the LMZ shrank significantly while the mixture zone expanded. The a-Al and Al_(12)(Fe,V)_3Si mixture zone was also observed in the HAZ, but another phase, submicron h-Al_(13)Fe_4 particles with rectangular or hexagonal shapes,formed along the melting pool border. Microhardness tests indicated that the hardness of the SLM-processed FVS0812 samples far exceeded that of the as-cast FVS0812 alloy. | Zheng Lijing Liu Yingying Sun Shaobo Zhang Hu | 2015 | Chinese Journal of Aeronautics2015，28，2： | 9 |
| 7 | Experimental study on performance of pneumatic seeding system显示文摘The purpose of this study was to promote the development of large-scale agricultural machines in China and meet the demand of air seeder localization.This study investigated the relationship between the working parameters and the performance of pneumatic seeding system,Cangmai 6004 wheat seed was used.A test platform for pneumatic seeding systems was developed,and then a series of experiments were performed based on the quadratic general rotary unitized design and response surface methodology(RSM).The seeding rate and the air flow rate were selected as affecting factors,coefficient of variation(CV)of evenness of feeding rate between rows and CV of seeding stability of total rows were assigned as the test indexes.Regression models between factors and indexes were established,and finally,an optimal equation based on this pneumatic seeding system were established as well,which can determine the proper air flow rate once the seeding rate was set based on the practical agronomic requirements.For example,when the seeding rate is set as 250 kg/hm^(2),the proper air flow rate of 7.53 m3/min can be obtained.The verification experiment results showed that the predicted working parameters obtained by RSM were feasible,which might provide a theoretical basis for further research of pneumatic seed metering systems. | Liu Lijing Yang Hui Ma Shaochun | 2016 | International Journal of Agricultural and Biological Engineering2016，9，6： | 7 |
| 8 | Record-Setting Ocean Warmth Continued in 2019显示文摘Human-emitted greenhouse gases(GHGs)have resulted in a long-term and unequivocal warming of the planet(IPCC,2019).More than 90%of the excess heat is stored within the world's oceans,where it accumulates and causes increases in ocean temperature(Rhein et al.,2013;Abram et al.,2019). | Lijing CHENG John ABRAHAM Jiang ZHU Kevin ETRENBERTH John FASULLO Tim BOYER Ricardo LOCARNINI Bin ZHANG Fujiang YU Liying WAN Xingrong CHEN Xiangzhou SONG Yulong LIU Michael EMANN | 2020 | Advances in Atmospheric Sciences2020，37，2： | 7 |
| 9 | Identification of a Ubiquitin-Binding Structure in the S-Locus F-Box Protein Controlling S-RNase-Based Self-Incompatibility显示文摘在 flowering 植物,自我障碍(SI ) 作为重要 intraspecific 服务繁殖障碍支持快。在从 Solanaceae, Plantaginaceae 和 Rosaceae, S-RNase 和 SLF (S 地点 F 盒子) 蛋白质的种类被显示了分别地控制 SI 的女、男的特性。然而,很少除了它的保存 F 盒子领域对 SLF 蛋白质的结构特征被知道。这里,我们证明 SLF C 终端区域拥有结构在 SLF 蛋白质家庭之中保存了的一个新奇 ubiquitin 有约束力的领域(UBD ) 。由使用 Nicotiana benthamiana 的一个 ex vivo 系统,我们发现 UBD 调停由 ubiquitin–proteasome 小径的 SLF 蛋白质周转。而且,我们检测了 SLF 蛋白质直接涉及 S-RNase 降级。一起拿,我们的结果提供新奇卓见进 SLF 结构并且在 S-RNase-based 自我障碍加亮 SLF 蛋白质稳定性和降级的一个潜在的角色。 | Guang Chen BinZhang Lijing Liu Qun Li Yu'e Zhang Qi Xie Yongbiao Xue | 2012 | Journal of Genetics and Genomics2012，39，2： | 7 |
| 10 | Comparative genomic and transcriptomic analyses uncover the molecular basis of high nitrogen-use efficiency in the wheat cultivar Kenong 9204显示文摘Studying the regulatory mechanisms that drive nitrogen-use efficiency(NUE)in crops is important for sustainable agriculture and environmental protection.In this study,we generated a high-quality genome assembly for the high-NUE wheat cultivar Kenong 9204 and systematically analyzed genes related to nitrogen uptake and metabolism.By comparative analyses,we found that the high-affinity nitrate transporter gene family had expanded in Triticeae.Further studies showed that subsequent functional differentiation endowed the expanded family members with saline inducibility,providing a genetic basis for improving the adaptability of wheat to nitrogen deficiency in various habitats.To explore the genetic and molecular mechanisms of high NUE,we compared genomic and transcriptomic data from the high-NUE cultivar Kenong 9204(KN9204)and the low-NUE cultivar Jing 411 and quantified their nitrogen accumulation under high-and low-nitrogen conditions.Compared with Jing 411,KN9204 absorbed significantly more nitrogen at the reproductive stage after shooting and accumulated it in the shoots and seeds.Transcriptome data analysis revealed that nitrogen deficiency clearly suppressed the expression of genes related to cell division in the young spike of Jing 411,whereas this suppression of gene expression was much lower in KN9204.In addition,KN9204 maintained relatively high expression of NPF genes for a longer time than Jing 411 during seed maturity.Physiological and transcriptome data revealed that KN9204 was more tolerant of nitrogen deficiency than Jing 411,especially at the reproductive stage.The high NUE of KN9204 is an integrated effect controlled at different levels.Taken together,our data provide new insights into the molecular mechanisms of NUE and important gene resources for improving wheat cultivars with a higher NUE trait. | Xiaoli Shi Fa Cui Xinyin Han Yilin He Long Zhao Na Zhang Hao Zhang Haidong Zhu Zhexin Liu Bin Ma Shusong Zheng Wei Zhang Jiajia Liu Xiaoli Fan Yaoqi Si Shuiquan Tian Jianqing Niu Huilan Wu Xuemei Liu Zhuo Chen Deyuan Meng Xiaoyan Wang Liqiang Song Lijing Sun Jie Han Hui Zhao Jun Ji Zhiguo Wang Xiaoyu He Ruilin Li Xuebin Chi Chengzhi Liang Beifang Niu Jun Xiao Junming Li Hong-Qing Ling | 2022 | Molecular Plant2022，15，9： | 6 |
| 11 | Hypothesis review:The direct interaction of food nanoparticles with the lymphatic system显示文摘Besides digestion and assimilation,there are other modes of direct interaction between food and human body.As it is known,the mucosal layer of the digestive tract interfaces with food after the digestion process.It has been demonstrated to uptake the micro-and nanoparticles via mucosa-associated lymphatic tissues(MALT).On the other hand,food is a typical polydisperse system and contains micro-and nanoparticles with different sizes and properties.Accordingly,it is hypothesized that food nanoparticles can directly interact with MALT and more specifically with the support of the preliminary experimental data from our research,that antioxidant nanoparticles can interact with the lymphatic vessels.This kind of interaction would be of great physiological importance.The confirmation of the hypothesis will establish a significant and novel approach to understand food system and provide answers to currently incomprehensible phenomena such as the biological functions of phytochemicals with low bioavailability.©2012 Production and hosting by Elsevier B.V.on behalf of Beijing Academy of Food Sciences. | Wei Lu Jingke Guo Jianwu Zhou Lijing Ke Shutao Liu Guanzhen Gao Huiqin Wang Wei Ding Pingfan Rao | 2012 | Food Science and Human Wellness2012，1，1： | 5 |
| 12 | Characterization and Fine Mapping of a Necrotic Leaf Mutant in Maize(Zea mays L.)显示文摘玉米(Zea mays L.) 是商业地重要的庄稼。它的收益能被变化在引起死亡的 biosynthetic 和 degradative 小径减少。在这份报纸,我们描述坏死的叶(nec-t ) 异种,从一根生来的线被获得, 81647。nec-t 异种植物与坏死的点有黄叶子,减少了叶绿素内容,并且变白的幼苗在正常生长条件下面死了。传播电子显微镜学揭示了散布 thylakoids,并且每房间减少了 grana lamellae 和叶绿体的数字。组织化学的染色建议 nec-t 叶子的那点形成可能由于房间死亡。基因分析证明那坏死被一个后退的地点的变化引起。用简单顺序重复标记, Nec-t 基因在染色体 2 的短手臂上在 mmc0111 和 bnlg2277 之间被印射。有从一张 F2 人口的变异的显型的 1287 个个人的一个总数被用于物理印射。Nec-t 基因在标记 T31 和 H8 之间位于 131.7 kb 的一个物理区域以内。 | Lijing Wang Shuai Han Shiyi Zhong Haizhong Wei Yanjun Zhang Yan Zhao Baoshen Liu | 2013 | Journal of Genetics and Genomics2013，40，6： | 5 |
| 13 | Effect of emodin on Aquaporin 5 expression in rats with sepsis-induced acute lung injury显示文摘OBJECTIVE: To investigate the effects of emodin on aquaporin 5(AQP5) expression in rats with sepsis-induced acute lung injury.METHODS: We divided 60 adult male Sprague-Dawley rats, weighing 200-230 g, into four groups: control, sham surgery, model and emodin groups(n = 15 for each). We created a sepsis model with cecal ligation and puncture; the sham surgery group had their cecums replaced after exposure outside the abdominal cavity. Each group was further divided into three subgroups(n = 5 for each)and expressions of AQP5 m RNA and proteins in lung tissue were measured by real-time fluorescence polymerase chain reaction and western blot at 6, 12 and 24 h after surgery.RESULTS: AQP5 expression did not change over time in the control group and sham surgery group,but decreased over time in the model group. The lowest expression was found in 12-h subgroup,which significantly differed from the 6-h subgroup(P < 0.01). Compared with the model group, AQP5 expression in the emodin group was significantly higher in all the subgroups(all P <0.01). Expressions in the 12-h subgroup were the highest, and significantly differed from the other subgroups. We found that lung tissue damage,such as pulmonary edema, alveolar damage and the exudation of red blood cells in pulmonary interstitium and alveolar, was significantly milder in the emodin group under light microscope than the model group.CONCLUSION: AQP5 expression was significantly down-regulated in rats with sepsis-induced acute lung injury induced by cecal ligation and puncture.Early prophylactic use of emodin can significantly enhance the AQP5 expression, thus effectively reducing the degree of pulmonary edema in septic rats. | Sun Yanni Sun Lijing Liu Shuqing Song Juan Cheng Jiejing Liu Jun | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 5 |
| 14 | Community replacement sequences and paleoenvironmental changes in reef areas of South China from Late Permian to Early Triassic exemplified by Panlongdong section in northeastern Sichuan Basin显示文摘The well-known Permian Changhsingian calcisponge reef located at Panlongdong section,Xuanhan county,northeastern Sichuan Basin has attracted wide attention.Due to severe dolomitization and poor quality of the fossils,the P-T boundary in this section is difficult to determine.This study,for the first time,recognized six communities in the Upper Permian Changhsingian Changxing Formation through the Lower Triassic Induan Feixianguan Formation of the Panlongdong section.They are Bryozoan-Archaeolithoporella-calcisponge Community,Calcareous green algae-foraminifer-crinoid Community,Microgastropod-foraminifer Community,Ostracod-microgastropod-cystic microbe Community,Ostracod-small brachiopod Community,and Non-calcified cyanobacteria Community.By using community replacement and palaeoenvironmental analysis,for the first time,we set the P-T boundary of the Panlongdong section at the middle of the calcimicrobialite containing cystic microbes.The community replacement sequence in the Panlongdong section is similar to that in other contemporaneous sections in reef areas of South China,indicating universal palaeoenvironmental changes during the Permian-Triassic transition.The results show that:(1)Changhsingian calcisponge reefs in South China generally vanished before the mass extinction and may be related to the large regression in the Late Permian.(2)The Calcareous green algae-foraminifer-crinoid Community replaced reef community and continued till the mass extinction.The mass extinction was probably related to the global sea-level drop.(3)The first aftermath community was dominated by specialized microgastropods,followed by the microbes,and then by the specialized microgastropods and small brachiopods.The succession of the three communities reflected the change in environmental conditions from dysoxic to anoxic and again to dysoxic.(4)In the Early Triassic,the relict community in shallow sea had very low diversity and low abundance,and was dominated by crinoids,gastropods,and bivalves. | LIU LiJing JIANG HongXia WU YaSheng CAI ChunFang | 2014 | Science China Earth Sciences2014，57，5： | 4 |
| 15 | Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity显示文摘Recent studies have shown that global translational reprogramming is an early activation event in pattern-triggered immunity,when plants recognize microbe-associated molecular patterns.However,it is not fully known whether translational regulation also occurs in subsequent immune responses,such as effector-triggered immunity(ETI).In this study,we performed genome-wide ribosome profiling in Arabidopsis upon RPS2-mediated ETI activation and discovered that specific groups of genes were translationally regulated,mostly in coordination with transcription.These genes encode enzymes involved in aromatic amino acid,phenylpropanoid,camalexin,and sphingolipid metabolism.The functional significance of these components in ETI was confirmed by genetic and biochemical analyses.Our findings provide new insights into diverse translational regulation of plant immune responses and demonstrate that translational coordination of metabolic gene expression is an important strategy for ETI. | Heejin Yoo George H.Greene Meng Yuan Guoyong Xu Derek Burton Lijing Liu Jorge Marques Xinnian Dong | 2020 | Molecular Plant2020，13，1： | 4 |
| 16 | Preparation of ceria-zirconia solid solution with enhanced oxygen storage capacity and redox performance显示文摘A new method called ultrasonic-assisted membrane reaction(UAMR)was reported for the fabrication of ceria-zirconia solid solution.A series of ceria-zirconia solid solutions with different Ce/Zr molar ratios were prepared by the UAMR method and characterized by Xray diffraction(XRD),N2 adsorption,hydrogen temperature-programmed reduction(H2-TPR),scanning electron microscope(SEM),and transmission electron microscopy(TEM)techniques.The UAMR method proved to be superior,especially when the Ce/Zr molar ratio was lower than 1,in fabricating ceria-zirconia solid solutions with large BET surface area,high oxygen storage capacity(OSC),and low reduction temperature. | Lijing MENG Licheng LIU Xuehong ZI Hongxing DAI Zhen ZHAO Xinping WANG Hong HE | 2010 | Frontiers of Environmental Science & Engineering2010，4，2： | 3 |
| 17 | Influence of co-solvent hydroxyl group number on properties of water-based conductive carbon pastes显示文摘 | Chengjie Hua Xiaoming Li Lijuan Shen Hong Lei Xiaoqian Guo Zhuo Liu Qingqiang Kong Lijing Xie cheng-Meng Chen | 2017 | Particuology2017，15，4： | 3 |
| 18 | Unfolded protein response activation compensates endoplasmic reticulum-associated degradation deficiency in Arabidopsis显示文摘Abiotic stresses often disrupt protein folding and induce endoplasmic reticulum(ER) stress. There is a sophisticated ER quality control(ERQC) system to mitigate the effects of malfunctioning proteins and maintain ER homeostasis. The accumulation of misfolded proteins in the ER activates the unfolded protein response(UPR) to enhance ER protein folding and the degradation of misfolded proteins mediate by ERassociated degradation(ERAD). That ERQC reduces abiotic stress damage has been well studied in mammals and yeast. However, in plants, both ERAD and UPR have been studied separately and found to be critical for plant abiotic stress tolerance. In this study, we discovered thatUPR-associated transcription factors Atb ZIP17, AtbZIP28 and AtbZIP60 responded to tunicamycin(TM) and Na Cl induced ER stress and subsequently enhanced Arabidopsis thaliana abiotic stress tolerance. They regulated the expression level of ER chaperones and the HRD1-complex components. Moreover, overexpression of Atb ZIP17,Atb ZIP28 and Atb ZIP60 could restore stress tolerance via ERAD in the HRD1-complex mutant hrd3a-2, which suggested that UPR and ERAD have an interactive mechanism in Arabidopsis. | Qingliang Li Hai Wei Lijing Liu Xiaoyuan Yang Xiansheng Zhang Qi Xie | 2017 | Journal of Integrative Plant Biology2017，59，7： | 3 |
| 19 | Tumor Suppressor Functions of miR-133a in Colorectal Cancer显示文摘 | Yujuan Dong Junhong Zhao Chung-Wah Wu Lijing Zhang Xiaodong Liu Wei Kang Wing-Wah Leung Ning Zhang Francis K.L. Chan Joseph J.Y. Sung Simon S.M. Ng Jun Yu | 2013 | Molecular Cancer Research2013，，9： | 3 |
| 20 | Upper Ocean Temperatures Hit Record High in 2020显示文摘The long-term warming of the ocean is a critical indicator of both the past and present state of the climate system. It also provides insights about the changes to come, owing to the persistence of both decadal variations and secular trends,which the ocean records extremely well(Hansen et al., 2011;IPCC, 2013;Rhein et al., 2013;Trenberth et al., 2016;Abram et al., 2019). | Lijing CHENG John ABRAHAM Kevin ETRENBERTH John FASULLO Tim BOYER Ricardo LOCARNINI Bin ZHANG Fujiang YU Liying WAN Xingrong CHEN Xiangzhou SONG Yulong LIU Michael EMANN Franco RESEGHETTI Simona SIMONCELLI Viktor GOURETSKI Gengxin CHEN Alexey MISHONOV Jim REAGAN Jiang ZHU | 2021 | Advances in Atmospheric Sciences2021，38，4： | 2 |
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