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| 1 | Spatiotemporal changes in vegetation coverage and its driving factors in the Three-River Headwaters Region during 2000-2011显示文摘The Three-River Headwaters Region(TRHR), which is the source area of the Yangtze River, Yellow River, and Lancang River, is of key importance to the ecological security of China. Because of climate changes and human activities, ecological degradation occurred in this region. Therefore, 'The nature reserve of Three-River Source Regions' was established, and 'The project of ecological protection and construction for the Three-River Headwaters Nature Reserve' was implemented by the Chinese government. This study, based on MODIS-NDVI and climate data, aims to analyze the spatiotemporal changes in vegetation coverage and its driving factors in the TRHR between 2000 and 2011, from three dimensions. Linear regression, Hurst index analysis, and partial correlation analysis were employed. The results showed the following:(1) In the past 12 years(2000–2011), the NDVI of the study area increased, with a linear tendency being 1.2%/10a, of which the Yangtze and Yellow River source regions presented an increasing trend, while the Lancang River source region showed a decreasing trend.(2) Vegetation coverage presented an obvious spatial difference in the TRHR, and the NDVI frequency was featured by a bimodal structure.(3) The area with improved vegetation coverage was larger than the degraded area, being 64.06% and 35.94%, respectively during the study period, and presented an increasing trend in the north and a decreasing trend in the south.(4) The reverse characteristics of vegetation coverage change are significant. In the future, degradation trends will be mainly found in the Yangtze River Basin and to the north of the Yellow River, while areas with improving trends are mainly distributed in the Lancang River Basin.(5) The response of vegetation coverage to precipitation and potential evapotranspiration has a time lag, while there is no such lag in the case of temperature.(6) The increased vegetation coverage is mainly attributed to the warm-wet climate change and the implementation of the ecological protection project. | LIU Xianfeng ZHANG Jinshui ZHU Xiufang PAN Yaozhong LIU Yanxu ZHANG Donghai LIN Zhihui | 2014 | Journal of Geographical Sciences2014，24，2： | 47 |
| 2 | Spatiotemporal changes of cold surges in Inner Mongolia between 1960 and 2012显示文摘在这研究,我们在内部蒙古和包围区域从 121 个气象学的车站用每日的最小的温度数据在在 1960 和 2012 之间的内部蒙古和他们的可能的开车因素分析了冷巨浪的空间与时间的变化。这些数据被分析利用一个 piecewise 回归模型,一个 Sen+Mann-Kendall 模型,和关联分析。结果证明(1 ) 单个车站的冷巨浪的频率在学习时期期间在内部蒙古减少了,与 0.5 times/10a (2.4 ~ 1.2 times/10a ) 的一个线性趋势。在 1991 以前, 1.1 times/10a (3.3 ~ 2.5 times/10a ) 的一个重要减少趋势被检测,当 0.45 times/10a (4.4 ~ 4.2 times/10a ) 的一个增加的趋势在 1991 以后被发现时。在季节的规模上,在春天寒冷巨浪的趋势与年度价值一致,并且在冷巨浪的最明显的变化发生在春天期间。每月冷的巨浪频率显示了 bimodal 结构,并且 11 月见证冷巨浪的最高的发生。(2 ) 空间地,冷巨浪的高发生主要在内部蒙古的北、中央的部分被观察,与观察在的更高的出现比在中央部分北。内部十的特征也揭示了那高频率,分别地,低频率区域在 1960 和 1990 之间介绍了减少并且增加的趋势。在 1990 年代以后扩展的高频率区域,和展出高冷的巨浪频率的区域主要在 Tulihe, Xiaoergou,和 Xi Ujimqin 旗帜被散布。(3 ) 在年度规模上,冷巨浪被 AO, NAO, CA, APVII,和 CQ 统治。然而,在冷巨浪的驱动力的季节的差别被检测。冬季冷巨浪显著地与 AO, NAO,史, CA, TPI, APVII, CW,和 IZ 被相关,显示他们被多重因素引起。秋天冷巨浪被 CA 和 IM 主要影响,当春天寒冷巨浪显著地与 CA 和 APVII 被相关时。 | LIU Xianfeng | 2015 | Journal of Geographical Sciences2015，25，3： | 11 |
| 3 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 4 | 基于桐油热处理的竹材理化性质研究显示文摘寻求绿色、可持续发展的改性方法来生产耐用竹材制品,是目前竹产业面临的挑战。本文将桐油热处理技术应用于竹材改性,探讨了桐油热处理过程中桐油在竹材中的渗透行为和分布,研究了桐油与热处理的协同作用对竹材化学性质、物理性质、力学性质的影响以及相互作用机制。结果表明,桐油热处理不仅可以增强竹材的疏水性能和尺寸稳定性,改善竹材的防霉性能,而且竹材可以保持其良好的力学性能。与未处理竹材相比,200℃桐油热处理后竹材的饱水膨胀率从3.17%下降至2.42%,200℃桐油热处理后竹材径切面的接触角在300 s时仍可保持在100°以上。桐油热处理后竹材性能的改善归因于竹材化学成分的变化、纤维结晶度的增加、竹材外表面和细胞腔内表面油膜的形成。因此,桐油热处技术在竹材工业改性中具有良好的发展前景。 | 费本华 唐彤 Tong Tang Bo Zhang Xianmiao Liu Wenbo Wang Xiufang Chen Benhua Fei | 2019 | 世界竹藤通讯2019，17，5： | 5 |
| 5 | Improved performance of aluminum pigments encapsulated in hybrid inorganic-organic films显示文摘An organic silane acrylate resin(PMBK) was synthesized by free-radical solution polymerization using methyl methacrylate,butyl acrylate and(3-methacryloxypropyl)trimethoxysilane as monomers.Aluminum(Al) particles were then encapsulated in inorganic-organic hybrid films that were prepared by hydrolysis and condensation of PMBK and tetraethyl orthosilicate(TEOS) on the surface of Al pigments.Characterization results showed that PMBK and TEOS could simultaneously hydrolyze and condense with hydroxyl groups on the surface of the Al particles to form composite Al particles coated with inorganic-organic hybrid films.Compared with raw Al particles,the corrosion resistance and adhesive properties of paint films containing the composite Al particles were improved greatly,while the glossiness of the paint films decreased slightly,from 48.6° to 47.0°.In alkaline media(pH 11),the volume of evolved H_2 of composite Al particles was only 3.5 mL,whereas that of raw Al was 83.5 mL.The glossiness of paint films containing composite Al particles decreased by 1.66%after immersion in alkaline media for24 h,whereas that of raw Al decreased by 14.82%.Peel-off tests of the paint films showed that the composite particles moved slightly away from the paint films.In contrast,the raw Al particles were seriously desquamated,suggesting encapsulation of hybrid films can greatly improve the adhesive properties of Al particles in paint films. | Pihui Pi Chao Liu Xiufang Wen Lianfu Zheng Shouping Xu Jiang Cheng | 2015 | Particuology2015，13，2： | 5 |
| 6 | Performance of different drought indices for agriculture drought in the North China Plain显示文摘The Palmer drought severity index(PDSI), standardized precipitation index(SPI), and standardized precipitation evapotranspiration index(SPEI) are used worldwide for drought assessment and monitoring. However, substantial differences exist in the performance for agricultural drought among these indices and among regions. Here, we performed statistical assessments to compare the strengths of different drought indices for agricultural drought in the North China Plain. Small differences were detected in the comparative performances of SPI and SPEI that were smaller at the long-term scale than those at the short-term scale. The correlation between SPI/SPEI and PDSI considerably increased from 1-to 12-month lags, and a slight decreasing trend was exhibited during 12-and 24-month lags, indicating a 12-month scale in the PDSI, whereas the SPI was strongly correlated with the SPEI at 1-to 24-month lags. Interestingly, the correlation between the trend of temperature and the mean absolute error and its correlation coefficient both suggested stronger relationships between SPI and the SPEI in areas of rapid climate warming. In addition, the yield–drought correlations tended to be higher for the SPI and SPEI than that for the PDSI at the station scale, whereas small differences were detected between the SPI and SPEI in the performance on agricultural systems. However, large differences in the influence of drought conditions on the yields of winter wheat and summer maize were evident among various indices during the crop-growing season. Our findings suggested that multi-indices in drought monitoring are needed in order to acquire robust conclusions. | LIU Xianfeng ZHU Xiufang PAN Yaozhong BAI Jianjun LI Shuangshuang | 2018 | Journal of Arid Land2018，10，4： | 3 |
| 7 | Demonstration of epitaxial growth of strain-relaxed GaN films on graphene/SiC substrates for long wavelength light-emitting diodes显示文摘Strain modulation is crucial for heteroepitaxy such as GaN on foreign substrates.Here,the epitaxy of strain-relaxed GaN films on graphene/SiC substrates by metal-organic chemical vapor deposition is demonstrated.Graphene was directly prepared on SiC substrates by thermal decomposition.Its pre-treatment with nitrogen-plasma can introduce C–N dangling bonds,which provides nucleation sites for subsequent epitaxial growth.The scanning transmission electron microscopy measurements confirm that part of graphene surface was etched by nitrogen-plasma.We study the growth behavior on different areas of graphene surface after pre-treatment,and propose a growth model to explain the epitaxial growth mechanism of GaN films on graphene.Significantly,graphene is found to be effective to reduce the biaxial stress in GaN films and the strain relaxation improves indium-atom incorporation in InGaN/GaN multiple quantum wells(MQWs)active region,which results in the obvious red-shift of light-emitting wavelength of InGaN/GaN MQWs.This work opens up a new way for the fabrication of GaN-based long wavelength light-emitting diodes. | Ye Yu Tao Wang Xiufang Chen Lidong Zhang Yang Wang Yunfei Niu Jiaqi Yu Haotian Ma Xiaomeng Li Fang Liu Gaoqiang Deng Zhifeng Shi Baolin Zhang Xinqiang Wang Yuantao Zhang | 2021 | Light(Science & Applications)2021，10，7： | 2 |
| 8 | Structural changes of the myofibrillar proteins in common carp ( Cyprinus carpio ) muscle exposed to a hydroxyl radical-generating system显示文摘 | Yanqing Li Baohua Kong Xiufang Xia Qian Liu Xinping Diao | 2013 | 2013 (5-6)2013，，5： | 2 |
| 9 | Relationship between microstructures and contents of Ca/P in near-eutectic Al–Si piston alloys显示文摘 | Jinguo Qiao Xiangfa Liu Xiangjun Liu Xiufang Bian | 2005 | Materials Letters2005，，14： | 2 |
| 10 | Phosphorylation of tau protein over time in rats subjected to transient brain ischemia显示文摘Transient brain ischemia has been shown to induce hyperphosphorylation of the microtubule-associated protein tau.To further determine the mechanisms underlying these processes,we investigated the interaction between tau,glycogen synthase kinase(GSK)-3βand protein phosphatase 2A.The results confirmed that tau protein was dephosphorylated during brain ischemia;in addition,the activity of GSK-3βwas increased and the activity of protein phosphatase2A was decreased.After reperfusion,tau protein was hyperphosphorylated,the activity of GSK-3βwas decreased and the activity of protein phosphatase 2A remained low.Importantly,the interaction of tau with GSK-3βand protein phosphatase 2A was altered during ischemia and reperfusion Lithium chloride could affect tau phosphorylation by regulating the interaction of tau with GSK-3βand protein phosphatase 2A,and improve learning and memory ability of rats after transient brain ischemia.The present study demonstrated that it was the interaction of tau with GSK-3βand protein phosphatase 2A,rather than their individual activities,that dominates the phosphorylation of tau in transient brain ischemia.Hyperphosphorylated tau protein may play an important role in the evolution of brain injury in ischemic stroke.The neuroprotective effects of lithium chloride partly depend on the inhibition of tau phosphorylation during transient brain ischemia. | Bo Song Qiang Ao Zhen Wang Weiqiang Liu Ying Niu Qin Shen Huancong Zuo Xiufang Zhang Yandao Gong | 2013 | Neural Regeneration Research2013，8，34： | 2 |
| 11 | A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer显示文摘Protein neddylation is catalyzed by a neddylation activating enzyme(NAE,E1),an E2 conjugating enzyme,and an E3 ligase.In various types of human cancers,the neddylation pathway is abnormally activated.Our previous study validated that the neddylation E2 UBE2F is a promising therapeutic target in lung cancer.Although the NAE inhibitor MLN4924/pevonedistat is currently under clinical investigation as an anti-cancer agent,there are no small molecules available that selectively target UBE2F.Here,we report,for the first time,the discovery,via structure-based virtual screen and chemical optimization,of such a small molecule,designated as HA-9104.HA-9104 binds to UBE2F,reduces its protein levels,and consequently inhibits cullin-5 neddylation.Blockage of cullin-5 neddylation inactivates cullin-RING ligase-5(CRL5)activity,leading to accumulation of the CRL5 substrate,NOXA,to induce apoptosis.Moreover,HA-9104 appears to form the DNA adduct via its 7-azaindole group to induce DNA damage and G2/M arrest.Biologically,HA-9104 effectively suppresses the growth and survival of lung cancer cells and confers radiosensitization in both in vitro cell culture and in vivo xenograft tumor models.In summary,we discovered a small molecule,designated HA-9104,that targets the UBE2F-CRL5 axis with anti-cancer activity alone or in combination with radiation. | Tiantian Xu Qisheng Ma Yanan Li Qing Yu Peichen Pan Yawen Zheng Zhijian Li Xiufang Xiong Tingjun Hou Bin Yu Hongmin Liu Yi Sun | 2022 | Signal Transduction and Targeted Therapy2022，7，11： | 2 |
| 12 | Influence of different thawing methods on physicochemical changes and protein oxidation of porcine longissimus muscle显示文摘 | Xiufang Xia Baohua Kong Jing Liu Xinping Diao Qian Liu | 2011 | LWT - Food Science and Technology2011，，1： | 2 |
| 13 | Radical scavenging activity of black currant ( Ribes nigrum L.) extract and its inhibitory effect on gastric cancer cell proliferation via induction of apoptosis显示文摘 | Na Jia Youling L. Xiong Baohua Kong Qian Liu Xiufang Xia | 2012 | Journal of Functional Foods2012，，1： | 2 |
| 14 | In situ TiB2 particulate reinforced near eutectic Al - Si alloy composites 显示文摘 | Yanfeng Hart Xiangfa Liu Xiufang Bian | 2002 | Composite Part A2002，，33： | 1 |
| 15 | Decreased expression of updated NESG1 in nasopharyngeal carcinoma: its potential role and preliminarily functional mechanism 显示文摘 | LIU Zhen LI Xin HE Xiufang | 2011 | Int J Cancer2011，128，11： | 1 |
| 16 | The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism显示文摘 | Heiying Jin Xuanzhong Tan Xiufang Liu Yijiang Ding | 2010 | International Journal of Colorectal Disease2010，，12： | 1 |
| 17 | The effect of magnesium on the antimony modification of A1-Si 显示文摘 | Bian Xiufang Chen Jurdlua Liu Xiangfa | 1997 | JOM1997，，2： | 1 |
| 18 | Antioxidant activity of black currant ( Ribes nigrum L.) extract and its inhibitory effect on lipid and protein oxidation of pork patties during chilled storage显示文摘 | Na Jia Baohua Kong Qian Liu Xinping Diao Xiufang Xia | 2012 | Meat Science2012，，4： | 1 |
| 19 | Influence of different thawing methods on physicochemical changes and protein oxidation of porcine longissimus muscle显示文摘 | X1A Xiufang KONG Baohua LIU Jing | 2012 | LWT-Food Science and Technology2012，46，1： | 1 |
| 20 | Effect of K/Na on Microstructure of High-speed Steel Used for Rolls显示文摘 | Pan Yichuan Yang Hua Liu Xiangfa Bian Xiufang | 2004 | Materials Letters2004，58，1213： | 1 |
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