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| 1 | TSPAN1 functions as an oncogene in gastric cancer and is downregulated by miR-573显示文摘 | Zhengmao Lu Tianhang Luo Mingming Nie Tao Pang Xin Zhang Xiaojun Shen Liye Ma Jianwei Bi Guo Wei Guoen Fang Xuchao Xue | 2015 | FEBS Letters2015，，： | 1 |
| 2 | Regulation of urease ex-pression of Actinomyces naeslundii in biofilms in re -sponse to pH and carbohydrate 显示文摘 | Liy Y Dan J Tao H | 2008 | Oral Microbiol Im-munol2008，23，4： | 1 |
| 3 | Laparoscopic Radical Correction Combined With Extensive Lymphadenectomy and Pelvic Autonomic Nerve Preservation for Mid-to-Low Rectal Cancer显示文摘 | Tao Liu Chao Zhang PeiWu Yu Jun Chen Dongzhu Zeng Lu Gan Wei Lv LiYe Liu Xiaochu Yan | 2011 | Clinical Colorectal Cancer2011，，3： | 1 |
| 4 | Structures and Properties of Thermo-regulated Knitted Fabrics 显示文摘 | ZHANG X X LIY TAO X M | 2005 | Indian Journal of Fibre and Textile Research2005，30，： | 1 |
| 5 | What should we do in China to close the implementation gap in health promotion? A response to WHO Nairobi Call to action 显示文摘 | LiY Tao M Fu H | 2011 | Global Health Promotion2011，18，2： | 1 |
| 6 | Investigation on the Novel High-performance Copper/Graphene Composite Conductor for High Power Density Motor显示文摘High-performance Cu/Graphene composite wire synergistically strengthened by nano Cr_(3)C_(2) phase was directly synthesized via hot press sintering followed by severe cold plastic deformation, using liquid paraffin and CuCr alloy powder as the raw materials. Since graphene is in situ formed under the catalysis of copper powder during the sintering process, the problem that graphene is easy to agglomerate and difficult to disperse uniformly in the copper matrix has been solved. The nano Cr_(3)C_(2)-particles nailed at the interface favor to improve the interface bonding. The Cu/Graphene composite possesses high electrical conductivity, hardness, and plasticity. The composite wire exhibits high electrical conductivity of 96.93% IACS, great tensile strength of 488MPa, and excellent resistance to softening. Even after annealing at 400℃ for 1 h, the tensile strength can still reach 268 MPa with a conductivity of about 99.14% IACS.The wire's temperature coefficient of resistance(TCR) is largely reduced to 0.0035/℃ due to the complex structure,which leads the wire to present low resistivity at higher temperatures. Such Cu/Graphene composite wire with excellent comprehensive performance has a good application prospect in high-power density motors. | Jiaxiao Wang Tingting Zuo Jiangli Xue Yadong Ru Yue Wu Zhuang Xu Yongsheng Liu Zhaoshun Gao Puqi Ning Tao Fan Xuhui Wen Li Han Liye Xiao | 2024 | CES Transactions on Electrical Machines and Systems2024，8，1： | 0 |
| 7 | Was Wuhan the early epicenter of the COVID-19 pandemic?——a critique显示文摘Recently, Worobey et al.(2022) published a report entitled ‘The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic' that succinctly summarizes their study [1]. A pre-print version of this study had earlier elicited a series of highprofile media coverages [2,3]. All these reports deliver a social-political message that the Huanan market is the epicenter of COVID-19. | Yanan Cao Lingling Chen Hua Chen Yupeng Cun Xiaofeng Dai Hongli Du Feng Gao Fengbiao Guo Yalong Guo Pei Hao Shunmin He Shunping He XiongLei He Zheng Hu Boon-Peng Hoh Xin Jin Qian Jiang Qinghua Jiang Asifullah Khan Hong-Zhi Kong Jinchen Li Shuai Cheng Li Ying Li Qiang Lin Jianquan Liu Qi Liu Jian Lu Xuemei Lu Shujin Luo Qinghua Nie Zilong Qiu Tieliu Shi Xiaofeng Song Jianzhong Su Sheng-ce Tao Chaolong Wang Chuan-Chao Wang Guo-Dong Wang Jiguang Wang Qi Wu Shaoyuan Wu Shuhua Xu Yu Xue Wenjun Yang Zhaohui Yang Kai Ye Yuan-Nong Ye Li Yu Fangqing Zhao Yiqiang Zhao Weiwei Zhai Dandan Zhang Liye Zhang Houfeng Zheng Qi Zhou Tianqi Zhu Ya-ping Zhang | 2023 | National Science Review2023，10，4： | 0 |
| 8 | Analysis of light propagation characteristic in the aero-optic flow field of cone-headed vehicle with side window显示文摘Aero-optic imaging deviation research is carried out for infrared-guided vehicle with cone-head side window,with a focus on the propagation characteristics of light in an aero-optic flow field.When the light entering the aero-optic flow field from the free-stream should be close to the normal,numerous data indicate that the light is refracted away from the normal.This paper divides the aero-optic flow field into two parts and uses the gas density distribution in the aero-optic flow field to propose the hypothesis that there are two modes of refraction when light propagates through the flow field.The results show that light propagates from the optically denser medium to the optically thinner medium after passing through the shock wave and eventually leads to refraction away from the normal when the light enters the aero-optic flow field. | XU Liang ZHOU Liye WANG Luyang ZHAO Shiwei WANG Tao | 2024 | Optoelectronics Letters2024，20，1： | 0 |
| 9 | A peroxidase-like single-atom Fe-N_(5)active site for effective killing human lung adenocarcinoma cells显示文摘Single-atom catalyst(SAC)is one of the newest catalysts,and attracts people’s wide attention in cancer therapy based on their characteristics of maximum specific catalytic activity and high stability.We designed and synthesized a Fe-N decorated graphene nanosheet(Fe-N5/GN SAC)with the coordination number of five.Through enzymology and theoretical calculations,the Fe-N5/GN SAC has outstanding intrinsic peroxidase-like catalytic activity due to single-atom Fe site with five-N-coordination structure.We explored its potential on lung cancer therapy,and found that it could kill human lung adenocarcinoma cells(A549)by decomposing hydrogen peroxide(H_(2)O_(2))into toxic reactive oxygen species(ROS)under acidic microenvironment in threedimensional(3D)lung cancer cell model.Our study demonstrates a promising application of SAC with highly efficient single-atom catalytic sites for cancer treatment. | Liye Zhu Hong Zhong Dan Du Tao Li Hoai Nguyen Scott PBeckman Wentao Xu Jin-Cheng Li Nan Cheng Yuehe Lin | 2023 | Nano Research2023，16，4： | 0 |
| 10 | UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGCip in hepatocellular carcinoma显示文摘The treatment for hepatocellular carcinoma(HCC)is promising in recent years,but still facing critical challenges.The first targeted therapy,sorafenib,prolonged the overall survival by months.However,resistance often occurs,largely limits its efficacy.Sorafenib was found to target the electron transport chain complexes,which results in the generation of reactive oxygen species(ROS).To maintain sorafenib resistance and further facilitate tumor progression,cancer cells develop strategies to overcome excessive ROS production and obtain resistance to oxidative stress-induced cell death.In the present study,we investigated the roles of ROS in sorafenib resistance,and found suppressed ROS levels and reductive redox states in sorafenib-resistant HCC cells.Mitochondria in sorafenib-resistant cells maintained greater functional and morphological integrity under the treatment of sorafenib.However,cellular oxygen consumption rate and mitochondria DNA content analyses revealed fewer numbers of mitochondria in sorafenib-resistant cells.Further investigation attributed this finding to decreased mitochondrial biogenesis,likely caused by the accelerated degradation of peroxisome proliferator-activated receptor y coactivator ip(PGC1P).Mechanistic dissection showed that upregulated UBQLN1 induced PGCip degradation in a ubiquitination-independent manner to attenuate mitochondrial biogenesis and ROS production in sorafenib-resistant cells under sorafenib treatment.Furthermore,clinical investigations further indicated that the patients with higher UBQLN1 levels experienced worse recurrence-free survival.In conclusion,we propose a novel mechanism involving mitochondrial biogenesis and ROS homeostasis in sorafenib resistance,which may offer new therapeutic targets and strategies for HCC patients. | Junjie Xu Lin Ji Yeling Ruan Zhe Wan Zhongjie Lin Shunjie Xia Liye Tao Junhao Zheng Liuxin Cai Yifan Wang Xiao Liang Xiujun Cai | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 0 |
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