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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 25 |
| 3 | Abnormal subchondral bone remodeling and its association with articular cartilage degradation in knees of type 2 diabetes patients显示文摘Type 2 diabetes(T2 D) is associated with systemic abnormal bone remodeling and bone loss. Meanwhile,abnormal subchondral bone remodeling induces cartilage degradation, resulting in osteoarthritis(OA).Accordingly, we investigated alterations in subchondral bone remodeling, microstructure and strength in knees from T2 D patients and their association with cartilage degradation. Tibial plateaus were collected from knee OA patients undergoing total knee arthroplasty and divided into non-diabetic(n = 70) and diabetes(n = 51) groups. Tibial plateaus were also collected from cadaver donors(n = 20) and used as controls.Subchondral bone microstructure was assessed using micro-computed tomography. Bone strength was evaluated by micro-finite-element analysis. Cartilage degradation was estimated using histology. The expression of tartrate-resistant acidic phosphatase(TRAP), osterix, and osteocalcin were calculated using immunohistochemistry. Osteoarthritis Research Society International(OARSI) scores of lateral tibial plateau did not differ between non-diabetic and diabetes groups, while higher OARSI scores on medial side were detected in diabetes group. Lower bone volume fraction and trabecular number and higher structure model index were found on both sides in diabetes group. These microstructural alterations translated into lower elastic modulus in diabetes group. Moreover, diabetes group had a larger number of TRAP^+ osteoclasts and lower number of Osterix^+ osteoprogenitors and Osteocalcin^+ osteoblasts. T2 D knees are characterized by abnormal subchondral bone remodeling and microstructural and mechanical impairments, which were associated with exacerbated cartilage degradation. In regions with intact cartilage the underlying bone still had abnormal remodeling in diabetes group, suggesting that abnormal bone remodeling may contribute to the early pathogenesis of T2 D-associated knee OA. | Yan Chen Yong-Can Huang Chun Hoi Yan Kwong Yuen Chiu Qingjun Wei Jingmin Zhao X Edward Guo Frankie Leung William W Lu | 2017 | Bone Research2017，5，4： | 10 |
| 4 | Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature. | D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) | 1997 | 畜牧与饲料科学1997，22，S1： | 3 |
| 5 | Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization显示文摘 | Gao W Soloff AC Lu X | | 0，，4： | 2 |
| 6 | Study on the chemical constituents in Abrus mollis 显示文摘 | Lu W J Tian X Y Chen J Y | 2003 | West China J Pharm Sci2003，18，6： | 2 |
| 7 | Effects of Ginkgo biloba extract and tanshinone on cytochrome P-450 isozymes and glutathione transferase in rats 显示文摘 | Yang X F Wang N P Lu W H | 2003 | Acta Pharmacol Sin2003，24，10： | 1 |
| 8 | Prediction of maximum daily ozone leve using combined neural network and statistical characteristics显示文摘 | WANG W J LU W Z WANG X K | 2003 | Environment International2003，，29： | 1 |
| 9 | Motion-compensated residue preprocessing in video coding based on just-noticeable-distortion profile显示文摘 | YANG X K LIN W S LU Z K | 2005 | IEEE Transactions on Circuits and Systems for Video Technology2005，15，6： | 1 |
| 10 | Metabolites of Colletotrichum gloeosporioides,an eddophytic fungus in Artemisia mongolica显示文摘 | Zou W X Meng J C Lu H | 2000 | J Nat Prod2000，63，： | 1 |
| 11 | 显示文摘 | Lu W X J Timko B P | 2005 | Proc Natl Acad Sci2005，102，10： | 1 |
| 12 | Preparation of anti-tetracycline antibodies and development of an indirect heterologous competitive enzyme-linked immunosorbent assay to detect residues of tetracycline in milk显示文摘 | Zhang Y Lu S X Liu W | 2007 | Agricultural and Food Chemistry2007，55，2： | 1 |
| 13 | Endogenous amino acid loss at the terminal ileum of rats fed water-extractable or alkali-extractable soluble non-starch polysaccharides obtained from wheat bran when fed with and without xylanase显示文摘 | HE Y H LU W Q PIAO X S | 2006 | Journal of Animal and Veterinary Advances2006，5，8： | 1 |
| 14 | A mechanical calculation of the flexible & floating anti-ship collision device for bridge piers显示文摘 | Lti W Lu R L Ning X L | 2012 | Advanced Materials Research2012，，： | 1 |
| 15 | Evolving trend and self-similarity of ozone pollution in central Hong Kong ambient during 1984-2002显示文摘 | Lu W Z Wang X K | 2006 | Science of The Total Environment2006，357，13： | 1 |
| 16 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009，4，2： | 1 |
| 17 | Improving the tensile properties of carbon fiber reinforced cemeng by ozone treatment of the fiber显示文摘 | Fu X L Lu W M Chung D D L | 1996 | Cement and Conrete Research1996，26，10： | 1 |
| 18 | Electrical and mechanical properties of expanded graphite-reinforced high-density polyethylene 显示文摘 | Zheng W G Lu X H Wong S C | 2004 | Appl Polym Sci2004，91，5： | 1 |
| 19 | Pseudo-correlation-function-based unambiguous tracking technique for Sin-BOC Signal显示文摘 | YAO Z CUI X W LU M Q | 2010 | IEEE Transactions on Aerospace and Electronic Systems2010，46，4： | 1 |
| 20 | Influence of ultrasonic power on the structure and composition of anodizing coatings formed on Mg alloys显示文摘 | GUO X W DING W J LU C | 2004 | Surface and Coatings Technology2004，183，23： | 1 |
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