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| 1 | Multimodal bioimaging based on gold nanorod and carbon dot nanohybrids as a novel tool for atherosclerosis detection显示文摘与多样的性质装备的先进 biocompatible 和柔韧的平台高度为动脉粥样硬化患者的早察觉在生物医学的成像应用程序被要求脉管的疾病和癌症。设计 nanohybrids 高贵金属镇静、荧光灯材料是执行多模式的成像克服单个形式的对应物的限制的一个新方法。此处,我们建议一个多模式的对比代理人的新奇设计;也就是,包括金 nanorods (GNR ) 的提高的 nanohybrid 和碳点(CD ) 与硅石(SiO 2) 作为一座桥。nanohybrid (GNR@SiO 2@CD) 建设基于在 SiO 2 和 silane-functionalized CD 之间结合的共有原子价,它与 CD 连接 GNR 形成典型核心壳单位。新奇结构不仅保留并且甚至高度改进 GNR 和 CD 的光性质,而且与赤裸的 GNR 或荧光染料和 CD 相比在散开思考(医生) 和荧光一生成像显微镜学(FLIM ) 大小拥有优异成像性能。GNR@SiO 2@CD nanohybrids 的优异 bioimaging 性质成功地被利用为,铺平向 vitro 医生和在像织物的幽灵以内的巨噬细胞的 FLIM 大小对比的 theranostic 的道路在为动脉粥样硬化和癌症的代理人。 | Xiaojing Liu Luting Liu Xiujie Hu Shuyun Zhou Rinat Ankri Dror Fixler Zheng Xie | 2018 | Nano Research2018，11，3： | 3 |
| 2 | A study of nonocrystalline TiO2 preparation with inorganotitanates and gelatin dispersant: thermal analysis of complex gel显示文摘 | Xiaoheng Liu Xin Wang Jiangrun Zhang Xi Hu Lute Lu | 1999 | Thermochimica Acta1999，，324： | 1 |
| 3 | Non-normal stochastic response of linear systems 显示文摘 | Lutes L D HU Sau-lon J | 1986 | Journal of Engineering Mechanics1986，112，2： | 1 |
| 4 | Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor显示文摘 | Xun Xu Yong Hou Xuyang Yin Li Bao Aifa Tang Luting Song Fuqiang Li Shirley Tsang Kui Wu Hanjie Wu Weiming He Liang Zeng Manjie Xing Renhua Wu Hui Jiang Xiao Liu Dandan Cao Guangwu Guo Xueda Hu Yaoting Gui Zesong Li Wenyue Xie Xiaojuan Sun Min Shi Zhiming | 2012 | Cell2012，，5： | 1 |
| 5 | Stochastic fatigue damage accumulation 显示文摘 | LUTES Loren D CORAZAO Miquel HU Sau-lon James | 1984 | Journal of Structural Engineering1984，110，11： | 1 |
| 6 | High performance streaked X-ray spectrometer for research of laser-produced plasmas显示文摘In order to mitigate the effect of the strong electromagnetic pulse, which produces laser-plasma interactions, we designed a new streaked X-ray spectrometer (SXS) enclosed within a well-sealed, electromag- netic interference-free cavity. The SXS can cover a wide selection of spectral windows using interchangeable Bragg crystals and by appropriate adjustment of the Bragg angle. The SXS has been used to observe time-re- solved X-ray spectrum in the 2.5 keV to 3.5 keV photon-energy range, resulting in a demonstrated spectral res- olution of about 13 at 2960 eV with a time resolution of 10 ps. The observed time and spectral resolutions dem- onstrate the applicability of the SXS for studies of laser-produced plasmas. | Guo Luting Wei Minxi Hu Xin Deng Keli Chen Tao Deng Bo Zhang Lu Zhao Yang Li Jin Xiao Shaoqiu Liu Shenye | 2016 | 强激光与粒子束2016，28，2： | 0 |
| 7 | Neuroprotective effects of ProBeptigen/CMI-168 on aging-induced cognitive decline and neuroinflammation in mice:a comparison with essence of chicken显示文摘Neuroinflammation and cognitive decline are the key pathological features in aging that bring detrimental impacts upon quality of life.However,there is no effective anti-aging pharmacological therapy thus far.Dietary supplements in particular essence of chicken(EC)has been found to be an effective remedy for alleviating mental stress and improving memory.In addition,a novel hydrolyzed chicken extract,ProBeptigen/CMI-168(PB),showed beneficial effects on cognitive ability.However,the antiaging effect and possible mechanism of PB and EC are still unknown.Here,we investigated the antiaging effects of PB and EC on hippocampus-related cognitive decline and neuroinflammation in aged mice.PB and EC were administered for 16 weeks in 10-month-old mice.Both PB and EC treatments ameliorated age-related deterioration of learning and memory,and attenuated oxidative stress and inflammation in the hippocampus.These results were associated with decreased inflammatory cytokine levels and increased neurotransmitter levels in the hippocampus.The overall effects of improving aging-induced cognitive decline were more robust in PB-treated mice,while EC was effective in decreasing oxidative stress and inflammation.Moreover,alterations in the diversity and composition of the gut microbiota in aged mice were also regulated by both PB and EC,which induced distinguished features in the gut microbiota and their related functions.This study showed that PB exerts neuroprotective effects in aged mice,the mechanism of which might be different from that of EC.Therefore,PB has a potential as dietary supplement for ameliorating cognitive dysfunction and neuroinflammation in elderly individuals. | Yinhua Ni Liyang Ni Lingyan Ma Zhe Wang Yufeng Zhao Luting Hu Liujie Zheng Zhengwei Fu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，4： | 0 |
| 8 | Transcriptome-wide association analysis identified candidate susceptibility genes for nasopharyngeal carcinoma显示文摘Dear Editor,Nasopharyngeal carcinoma(NPC)is a common malignancy in East and Southeast Asia,especially in South China.The etiology of NPC has been linked to genetic susceptibility,Epstein-Barr virus(EBV)infection,and environmental factors.Accumulated evidence including multiple genome-wide association studies(GWASs)has revealed robust genetic predisposition of NPC.However,GWAS-identified genetic variants collectively account for only 8.2%of NPC heritability[1].The underlying inherited predisposition is largely undetermined.The strongest genetic signal for NPC consistently hits the human leukocyte antigen(HLA)region on 6p21[2].However,the highly polymorphic nature and complicated long-range linkage disequilibrium(LD)in the HLA region particularly obscure the causal variants driving the association.In addition,most genetic variants located in introns or intergenic regions.The causal genes mediating genetic effects on NPC risk have rarely been ascertained by GWAS alone. | Yong-Qiao He Wen-Qiong Xue Dan-Hua Li Tong-Min Wang Zhi-Ming Mai Da-Wei Yang Chang-Mi Deng Ying Liao Wen-Li Zhang Ruo-Wen Xiao Luting Luo Hua Diao Xiating Tong Yanxia Wu Jiang-Bo Zhang Ting Zhou Xi-Zhao Li Pei-Fen Zhang Xiao-Hui Zheng Shao-Dan Zhang Ye-Zhu Hu Minzhong Tang Yuming Zheng Yonglin Cai Ellen T.Chang Zhe Zhang Guangwu Huang Su-Mei Cao Qing Liu Lin Feng Ying Sun Maria Li Lung Hans-Olov Adami Weimin Ye Tai-Hing Lam Wei-Hua Jia | 2022 | Cancer Communications2022，42，9： | 0 |
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