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| 1 | 减少全球NO_x排放:开发先进的能量和运输技术显示文摘从全球范围来讲,未来能量需求将会持续增长。由于发展中国家要提高其生活水平,因此,在可预见的将来,全球NO_x排放会呈现出不断增加的趋势。美国采取了一些改善措施来减少固定和流动污染源的NO_x排放,以减少对臭氧层的损坏。同时需要采取进一步的改进措施以降低与NO_x排放有关的对身体健康和生态系统的影响。由于对电力和运输需求的增长,在世界上其他地区(尤其是发展中国家)NO_x排放一直在稳定增长。如果实施适当的政策措施,能源和运输技术的改善会有助于减少NO_x排放。这篇论文评价了商用电力生产和运输技术,相对于传统技术而言,它们排放较少的NO_x,同时还评价了近10年内商用方面的先进技术。文章还评估了可以在地区、国家和全球水平上实施的不同政策措施,以此来促进这些先进技术的开发并最终减少NO_排放。论文提出了技术飞跃的概念,很可能有助于发展中国家缩减那些导致NO_x排放增大的项目。 | Michael J.Bradley Brian M.Jones 肖玉 | 2002 | AMBIO-人类环境杂志2002,31,2: | 6 |
| 2 | Recent advances and future directions in preclinical research of argininevasopressin(AVP) receptor blocker conivaptan in the context of stroke显示文摘Stroke is a major cause of mortality and permanent disability.The onset of stroke is followed by life-threatening pathophysiological responses including brain edema,elevation of intracranial pressure,disruption of blood-brain barrier(BBB),brain infarct and permanent tissue damage.Brain edema develops due to accumulation of water in intracellular and extracellular compartments of the brain,which causes an increase in brain volume and elevation | Emil Zeynalov Susan M.Jones | 2016 | Neural Regeneration Research2016,11,3: | 5 |
| 3 | 几种络合剂的驱铅效果实验显示文摘小鼠一次或多次腹腔注射醋酸铅后,分别投给DMSA、Na_2CaEDTA、DPA、Na_3CaDTPA 和DMPS 测定这几种络合剂降低肝、肾、脾、骨和脑组织铅含量的效应。结果发现,在一些实验条件下,用络合剂处理后小鼠肝、肾、骨和脑铅含量明显低于对照组。检测的几种络合剂中,不论腹腔注射还是胃管注入DMSA,其从组织中驱铅的能力均比其它种络合剂更有效。结果提示这种络合剂是有发展前途的,值得临床上深入研究。 | 徐兆发 Mark M.Jones | 1990 | 中华劳动卫生职业病杂志1990,8,5: | 5 |
| 4 | The Soft X-ray Imager(SXI)on the SMILE Mission显示文摘The Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.SMILE is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in 2025.SXI is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SMILE orbit.SXI is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s exosphere.SWCX provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field lines.The sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SMILE will enable such movements to be tracked for segments lasting many hours.SXI is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States. | S.Sembay A.L.Alme D.Agnolon T.Arnold A.Beardmore A.Belén Balado Margeli C.Bicknell C.Bouldin G.Branduardi-Raymont T.Crawford J.P.Breuer T.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor T.Crawford N.Eaton C.Feldman C.Forsyth T.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer M.Guedel Y.Guo M.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh M.W.J.Hubbard H.Jeszenszky M.Jones T.Kennedy K.Koch-Mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.Martindale J.Miguel Mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter T.Pouliantis B.H.Qureshi W.Raab G.Randal A.M.Read N.M.M.Roque M.E.Rostad C.Runciman S.Sachdev A.Samsonov M.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland M.Steller TianRan Sun J.Thornhill W.Thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang | 2024 | Earth and Planetary Physics2024,8,1: | 4 |
| 5 | Development and validation of the Diabetes Bowel Symptom Questionnaire显示文摘 | C.Quan N. J.Talley S.Cross M.Jones J.Hammer N.Giles M.Horowitz | 2003 | Alimentary Pharmacology & Therapeutics2003,,9: | 1 |
| 6 | The methodology of nutritional screening and assessment tools显示文摘 | J. M.Jones | 2002 | Journal of Human Nutrition and Dietetics2002,,1: | 1 |
| 7 | 植物细胞和组织培养的利用显示文摘植物细胞和组织培养技术具有加快育种和繁殖过程,减少劳动,节省空间等特点,目前已作为一种实验系统广泛用于科研和生产.近期应用的技术有快述繁殖、体细胞胚的发生、脱毒、胚培养、单倍体育种、种质贮存与运输以及细胞代谢物的生产等,而体细胞无性系变异、通过原生质体融合进行基因转化、通过农杆菌或其他手段向植物导入基因等又是很有发展趋势的新技术,现将有关这些技术的原理和方法介绍如下: | M.Jones 蒋有绎 | 1990 | 北京农业科学1990,,1: | 1 |
| 8 | CSRP’s Impact on Low‐Income Preschoolers’ Preacademic Skills: Self‐Regulation as a Mediating Mechanism显示文摘 | C. CybeleRaver Stephanie M.Jones ChristineLi‐Grining FuhuaZhai KristenBub EmilyPressler | 2011 | Child Development2011,,1: | 1 |
| 9 | Moving beyond hydroxychloroquine:the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies显示文摘Autophagy is a lysosomal-mediated degradation pro-cess that controls the turnover of organelles and long-lived proteins.Outside of its role in maintaining cellu-lar homeostasis,autophagy is frequently stimulated in response to stress conditions such as those imposed by chemotherapy,nutrient deprivation,and microenviron-mental disruption.In this capacity,autophagy serves as a mechanism to generate alternative sources of metabolic fuel that promote survival when preferred energy gener-ating pathways are impaired[1].Over the past decade,stress-induced autophagy has emerged as an important driver of malignant progression and anticancer drug resistance.Virtually all classes of clinically relevant anti-cancer agents,as well as radiotherapy,have been dem-onstrated to stimulate autophagy in preclinical studies[2].In the overwhelming majority of cases,genetically or pharmacologically impairing autophagy has been shown to yield therapeutic benefit in a manner that significantly improves the efficacy of the relevant agents or modalities[3]. | Trace M.Jones Claudia Espitia Wei Wang Steffan T.Nawrocki Jennifer S.Carew | 2019 | Cancer Communications2019,39,1: | 1 |
| 10 | 组织培养引起的遗传变异性和不稳定性显示文摘在组织培养的过程中,如果经过愈伤组织阶段,就会导致遗传不稳定性,这种现象就称作体细胞无性系变异(Somaclonal variation).最早报道的实例是甘蔗,在再生植株中出现形态上的变化,如叶耳的长短和茸毛的有无,染色体数目也有所不同,3种同功酶(过氧化物酶、氨基转移酶,淀粉酶)分析,以及甘蔗的直立性、粗细和含糖量、抗病性等也都发生了变异. | M.Jones 蒋有绎 | 1990 | 北京农业科学1990,,1: | 1 |
| 11 | The long‐term results of Anderson–Hynes pyeloplasty显示文摘 | P.H.O’Reilly P.J.C.Brooman S.Mak M.Jones C.Pickup C.Atkinson A.J.Pollard | 2008 | BJU International2008,,: | 1 |
| 12 | Excellent response rate of anismus to botulinum toxin if rectal prolapse misdiagnosed as anismus (‘pseudoanismus’) is excluded显示文摘 | R.Hompes C.Harmston N.Wijffels O. M.Jones C.Cunningham I.Lindsey | 2012 | Colorectal Disease2012,,: | 1 |
| 13 | Catching the habit: a study of inequality of opportunity in smoking‐related mortality显示文摘 | SilviaBalia Andrew M.Jones | 2011 | Journal of the Royal Statistical Society: Series A (Statistics in Society)2011,,1: | 1 |
| 14 | Developing an identities-based approach to support more robust resilience and recovery in heritage planning and management显示文摘Resilience has become an increasingly important concept in the cultural heritage feld,particularly in the aftermath of the unprecedented challenges the COVID-19 global pandemic brought.However,on a conceptual and practical level,resilience remains closely linked to the technical conservation of built heritage,and there remains a need to develop broader approaches inclusive of cultural and socioeconomic components.This article investigates the potential applicability of theoretical concepts linked to identity and identities in heritage planning to help fll these gaps and develop approaches that consider resilience and are better able to address a range of unanticipated disasters.We frst review the literature and policy documents to defne and identify the potential for identities-based approaches.We then examine the case of Matera,an extremely fragile world heritage site in southern Italy that has been continuously inhabited for more than 8000 years and provides a relevant example of resilience.We explore the trends and efects of globalised tourism development before the pandemic and the post pandemic emergence of more local/regional and slow tourism patterns,largely based on cultural solutions to local development challenges and knowledge exchange.Through this comparison,we analyse the potential and limitations of introducing identities-based concepts into heritage planning as a more robust way to enhance resilience and prepare cities for unexpected future crises. | Zachary M.Jones Théodora Pappas | 2023 | Built Heritage2023,7,2: | 0 |
| 15 | ABA signaling prevents phosphodegradation of the SR45 splicing factor to alleviate inhibition of early seedling development in Arabidopsis显示文摘Serine/arginine-rich(SR)proteins are conserved splicing regulators that play important roles in plant stress responses,namely those mediated by the abscisic acid(ABA)hormone.The Arabidopsis thaliana SR-like protein SR45 is a described negative regulator of the ABA pathway during early seedling development.How the inhibition of growth by ABA signaling is counteracted to maintain plant development under stress conditions remains largely unknown.Here,we show that SR45 overexpression reduces Arabidopsis sensitivity to ABA during early seedling development.Biochemical and confocal microscopy analyses of transgenic plants expressing fluorescently tagged SR45 revealed that exposure to ABA dephosphorylates the protein at multiple amino acid residues and leads to its accumulation,due to SR45 stabilization via reduced ubiquitination and proteasomal degradation.Using phosphomutant and phosphomimetic transgenic Arabidopsis lines,we demonstrate the functional relevance of ABA-mediated dephosphorylation of a single SR45 residue,T264,in antagonizing SR45 ubiquitination and degradation to promote its function as a repressor of seedling ABA sensitivity.Our results reveal a mechanism that negatively autoregulates ABA signaling and allows early plant growth under stress via posttranslational control of the SR45 splicing factor. | Rui Albuquerque-Martins Dora Szakonyi James Rowe Alexander M.Jones Paula Duque | 2023 | Plant Communications2023,4,2: | 0 |
| 16 | 不同社交距离下口罩对气溶胶化新冠病毒替代物的过滤效率显示文摘The coronavirus disease 2019(COVID-19)pandemic is an unpreedented global event.It has become clear that COVID-19 is transmitted by virus-containing droplets(>5μm)and aerosols(<5μm),and that all human exhalatory activities(e.g.,breathing,speaking,singing,shouting,coughing,and sneezing)result in the emission of suspended droplets/aerosols of various sizes.As an example,COVID-19 patients exhale millions of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)RNA copies into the air per hour[1].SARS-CoV-2-laden aerosols play a profound role in disease transmission,as they can linger and remain viable in the air for a long duration(~16 h)[2]and travel a long distance(~4.8 m)due to their smaller size[3]. | 唐宋 李霞 丁培 毛怡心 邓富昌 查玉娥 庄思琪 丁珵 王姣 王友斌 赵晓宁 Rachael M.Jones 阚飙 C.Raina MacIntyre 徐东群 施小明 | 2022 | Science Bulletin2022,67,6: | 0 |
| 17 | Mobilization of Lead by Several Chelating Agents in Mice Injected with Lead显示文摘The relative abilities of several chelating agents to act as antagonists for acute and chronic lead poisoning have been examined in the mouse.The acute LD50 for lead acetate trihydrate was determined and found to be 135.3 mg Pb/kg for i. p. injection with a 95% confidence interval of 87.1 to 210.3 mg Pb/kg. The relative efficacy of chelating agents to reduce liver,kidney, spleen, bone and brain levels of lead was determined. The spleen levels were found to undergo little differences between the control and treated groups, but the liver, kidney, bone and brain levels showed significant differences in some cases. Of the compounds examind, meso-2, 3-dimercaptosuccinic acid (DMSA)and sodium 2,3-dimercaptopropane-1-sulfonate(DMPS) were as effective as disodium calcium ethylenediaminetetraacetate (Na2CaEDT A). The resuits indicated that DMSA was a promising chelating agent and may be worthy of further investigation in the clinic. | 徐兆发 Mark M.Jones | 1989 | 中国医科大学学报1989,18,S2: | 0 |
| 18 | Arterial Stiffness as a Cardiovascular Risk Factor in Prostate Cancer Survivors:A Case-Control Study显示文摘Purpose In New Zealand,prostate cancer (PCa) is the most commonly diagnosed cancer in men and the third most common cause of male cancer deaths.Among these patients,the most common non-cancer related cause of death is cardiovascular disease (CVD).Aortic arterial stiffness may be clinically viable solution for detecting and tracking CVD risk factor in PCa survivors.The aim of the study was to determine whether aortic arterial stiffness is increased in PCa survivors compared to age-matched controls.Methods Participants recruited for this prospective comparative study were PCa survivors who had completed treatment(other than endocrine therapy) or were on active surveillance compared,or were age-matched non-cancer controls.During a single 1-h appointment,all participants had measures of aortic arterial stiffness,arterial wave reflection,central blood pressure and body composition taken.Results Ninety-eight men were recruited,51 PCa survivors and 47 controls.There was no significant between group dif-ference for aortic arterial stiffness[12.0 m/s (SD:1.7) vs.12.0 m/s (SD:1.9),P=0.953,d=0.0].Fat free mass[60.7 kg(SD:4.9) vs.65.1 kg (SD:8.3),P=0.007,d=0.6]and skeletal muscle index[8.6 kg/m2 (SD:0.6) vs.9.0 kg/m2 (SD:0.9),P=0.050,d=0.5]were lower in the PCa group.Conclusions Aortic arterial stiffness is not increased (worse) in men with PCa who receive various treatments,compared to age-matched controls.These findings may indicate that factors other than increased aortic arterial stiffness contribute to heightened risk of cardiovascular events in this population. | Lynnette M.Jones Rebekah Wilson Lee Stoner J.Chris Baldi | 2021 | Journal of Science in Sport and Exercise2021,3,2: | 0 |
| 19 | The Third Generation(e,e'K^+) Λ Hypernuclear Spectroscopy at JLab显示文摘We are now preparing for the third generation (e,e' K+) Λ hypernuclear spectroscopic experiment at Hall C,Jefferson Lab (USA). The goal of the experiment is the precise spectroscopy of hypernuclei in wide mass region. We have constructed a new high resolution electron spectrometer 'HES' dedicated to (e,e' K+) hypernuclear study in Japan and it was shipped to JLab in February,2008. We will discuss about the physics of the (e,e' K+) hypernuclear study at JLab and report the current preparation status of the third generatrion experiment. | D.Kawama A.Acha I.Albayrak D.Androic O.Ates P.Baturin B.Beckford W.Boeglin A.Bruell M.Christy R.Ent H.Fenker Y.Fujii M.Furic D.Gaskell S.Gogami O.Hashimoto T.Horn V.Hungerford Ed M.Jones H.Kanda C.Keppel M.Kohl L.Kramer A.Liyanage P.Markowitz T.Maruta A.Matsumura S. N.Nakamura T.Petkovic B.Raue J.Reinhold T.Seva A.Shichijo G.Smith N.Taniya W.Vulcan T.Walton S. A.Wood T.Yamamoto K.Yokota | 2009 | 原子核物理评论2009,26,S1: | 0 |
| 20 | G protein controls stress readiness by modulating transcriptional and metabolic homeostasis in Arabidopsis thaliana and Marchantia polymorpha显示文摘The core G protein signaling module,which consists of Gαand extra-large Gα(XLG)subunits coupled with the Gβγdimer,is a master regulator of various stress responses.In this study,we compared the basal and salt stress-induced transcriptomic,metabolomic and phenotypic profiles in Gα,Gβ,and XLG-null mutants of two plant species,Arabidopsis thaliana and Marchantia polymorpha,and showed that G protein mediates the shift of transcriptional and metabolic homeostasis to stress readiness status.We demonstrated that such stress readiness serves as an intrinsic protection mechanism against further stressors through enhancing the phenylpropanoid pathway and abscisic acid responses.Furthermore,WRKY transcription factors were identified as key intermediates of G protein-mediated homeostatic shifts.Statistical and mathematical model comparisons between A.thaliana and M.polymorpha revealed evolutionary conservation of transcriptional and metabolic networks over land plant evolution,whereas divergence has occurred in the function of plant-specific atypical XLG subunit.Taken together,our results indicate that the shifts in transcriptional and metabolic homeostasis at least partially act as the mechanisms of G protein-coupled stress responses that are conserved between two distantly related plants. | Ting-Ying Wu Shalini Krishnamoorthi Kulaporn Boonyaves Isam Al-Darabsah Richalynn Leong Alan M.Jones Kimitsune Ishizaki Kang-Ling Liao Daisuke Urano | 2022 | Molecular Plant2022,15,12: | 0 |