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| 1 | In Vitro Evaluation of the Feasibility of Commercial Zn Alloys as Biodegradable Metals显示文摘In this work, three widely used commercial Zn alloys(ZA4-1, ZA4-3, ZA6-1) were purchased and prepared by hot extrusion at 200 °C. The microstructure, mechanical properties, corrosion behaviors,biocompatibility and hemocompatibility of Zn alloys were studied with pure Zn as control. Commercial Zn alloys demonstrated increased strength and superb elongation compared with pure Zn. Accelerated corrosion rates and uniform corrosion morphologies were observed in terms of commercial Zn alloys due to galvanic effects between Zn matrix and α-Al phases. 100% extracts of ZA4-1 and ZA6-1 alloys showed mild cytotoxicity while 50% extracts of all samples displayed good biocompatibility. Retardant cell cycle and inhibited stress fibers expression were observed induced by high concentration of Zn^(2+) releasing during corrosion. The hemolysis ratios of Zn alloys were lower than 1% while the adhered platelets showed slightly activated morphologies. In general, commercial Zn alloys possess promising mechanical properties, appropriate corrosion rates, significantly improved biocompatibility and good hemocompatibility in comparison to pure Zn. It is feasible to develop biodegradable metals based on commercial Zn alloys. | C.Wang H.T.Yang X.Li Y.F.Zheng | 2016 | Journal of Materials Science & Technology2016，32，9： | 21 |
| 2 | Mechanisms of ultraviolet disinfection and chlorination of Escherichia coli: Culturability, membrane permeability,metabolism, and genetic damage显示文摘Traditional culture methods may underestimate the tolerance of microorganisms to disinfectants because of the existence of viable but nonculturable or sublethally injured cells after disinfection.The selection of a strict method is crucial for the evaluation of disinfection performance.The actions of 2 typical disinfectants–ultraviolet(UV)and chlorine–on the fecal indicator Escherichia coli were investigated by the detection of culturability,membrane permeability,metabolic activity,deoxyribonucleic acid(DNA),and messenger ribonucleic acid(m RNA).During UV disinfection,the irreversible damages in the cell membrane and cellular adenosine triphosphate(ATP)were negligible at low UV doses(<80 m J/cm^2).However,membrane permeability was damaged at low doses of chlorine(<5 mg/L),leading to leakage of cellular ATP.Our study showed that a slight lesion in DNA was detected even at high doses of UV(400 m J/cm^2)and chlorine(>5 mg/L)treatments.The decay of m RNA was more rapid than that of DNA.The degradation level of m RNA depended on the choice of target genes.After exposure to 50 m J/cm^2UV dose or 5 mg/L chlorine for30 min,the DNA damage repair function(Rec A m RNA)was inhibited.The m RNA involved in the DNA damage repair function can be a potential indicator of bacterial viability. | Limei Xu Chongmiao Zhang Pengcheng Xu Xiaochang C.Wang | 2018 | Journal of Environmental Sciences2018，30，3： | 10 |
| 3 | Dynamic membrane bioreactor performance enhancement by powdered activated carbon addition:Evaluation of sludge morphological,aggregative and microbial properties显示文摘The effects of powdered activated carbon(PAC) addition on sludge morphological, aggregative and microbial properties in a dynamic membrane bioreactor(DMBR) were investigated to explore the enhancement mechanism of pollutants removal and filtration performance. Sludge properties were analyzed through various analytical measurements. The results showed that the improved sludge aggregation ability and the evolution of microbial communities affected sludge morphology in PAC-DMBR, as evidenced by the formation of large, regularly shaped and strengthened sludge flocs. The modifications of sludge characteristics promoted the formation process and filtration flux of the dynamic membrane(DM) layer. Additionally, PAC addition did not exert very significant influence on the propagation of eukaryotes(protists and metazoans)and microbial metabolic activity. High-throughput pyrosequencing results indicated that adding PAC improved the bacterial diversity in activated sludge, as PAC addition brought about additional microenvironment in the form of biological PAC(BPAC), which promoted the enrichment of Acinetobacter(13.9%), Comamonas(2.9%), Flavobacterium(0.31%) and Pseudomonas(0.62%), all contributing to sludge flocs formation and several(such as Acinetobacter) capable of biodegrading relatively complex organics. Therefore, PAC addition could favorably modify sludge properties from various aspects and thus enhance the DMBR performance. | Zhenzhen Yu Yisong Hu Mawuli Dzakpasu Xiaochang C.Wang Huu Hao Ngo | 2019 | Journal of Environmental Sciences2019，31，1： | 9 |
| 4 | 腰痛患者MRI上各节段腰椎间盘退变形式与年龄的相关性分析显示文摘目的:探讨腰痛患者MRI上各节段腰椎间盘退变形式与年龄的相关性。方法:回顾性分析2004~2006年共529例就诊于加州大学洛杉矶分校Santa Monica骨科医院脊柱外科中心的腰痛伴或不伴有腿痛患者(男191例,女338例)的腰椎MRI资料,根据患者年龄分为5组,≤29岁、30~39岁、40~49岁、50~59岁及≥60岁组。按Pfirrmann′s分级系统对每例患者腰椎各节段的椎间盘(L1/2~L5/S1)退变程度进行分级,所得数据采用SPSS13.0进行统计学分析,总结其退变模式。结果:71例(13.4%)患者L1/2~L5/S1椎间盘退变程度表现为1-1-1-1-1,为正常椎间盘,是所有组合中最常见的。低年龄组发生严重退变(4级)的几率最低,L1/2、L2/3、L3/4椎间盘退变程度较L4/5、L5/S1低;1-1-1-1-1的发生率随着年龄的增加而明显降低,而1-1-1-1-2和1-1-1-1-3与之相反,发生率随着年龄的增加而明显升高。40岁以前,1-1-1-1-1的发生率最高;在40~49岁年龄组中,1-1-1-1-3的发生几率最高,为7.6%,而超过50岁,3-3-3-3-3发生的几率最高。单节段退变发生率与年龄呈负相关(P<0.01),随着年龄的增大而降低;而所有节段退变的发生率与年龄呈正相关(P<0.01),随着年龄的增大而增加。结论:在腰痛患者中,腰椎单一节段退变所占比例随年龄增大而减小,而所有节段退变所占比例随年龄增大而增大。 | 蒋欣 Yuiehiro Morishita Hymanson Henry Jeffrey C.Wang | 2009 | 中国脊柱脊髓杂志2009，19，11： | 9 |
| 5 | Mechanical properties and deformation mechanisms of Ti-3Al-5Mo-4.5V alloy with varied β phase stability显示文摘Evolution of deformation mechanisms and mechanical properties of Ti-3Al-5Mo-4.5V alloy with different β phase stability have been systematically investigated. β phase stability alteration is achieved through quenching temperature variation from dual α+β field(700℃) to single β field(880℃). Tensile tests at ambient temperature show that apparent yield strength of the alloy experiences an abrupt decrease followed by a significant increase from 700℃ to 880℃. Work hardening behavior is characterized by transition from the initial two-regime feature to the three-stage outlook. Concurrently, the maximum working hardening rate drops from 14000 MPa to 3000 MPa, which is concurrent with the shrinking volume fraction of primary a phase. Detailed discussion about the relationship between deformation mechanisms and β phase stability has been outlined. | Q.Xue Y.J.Ma J.F.Lei R.Yang C.Wang | 2018 | Journal of Materials Science & Technology2018，34，12： | 8 |
| 6 | pH-responsive mesoporous silica nanoparticles employed in controlled drug delivery systems for cancer treatment显示文摘In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles(MSNs) with a functional surface possess obvious advantages and were thus rapidly developed for cancer treatment. Many stimuli-responsive materials, such as nanoparticles, polymers, and inorganic materials, have been applied as caps and gatekeepers to control drug release from MSNs. This review presents an overview of the recent progress in the production of pH-responsive MSNs based on the pH gradient between normal tissues and the tumor microenvironment. Four main categories of gatekeepers can respond to acidic conditions. These categories will be described in detail. | Ke-Ni Yang Chun-Qiu Zhang Wei Wang Paul C.Wang Jian-Ping Zhou Xing-Jie Liang | 2014 | Cancer Biology & Medicine2014，11，1： | 8 |
| 7 | Evolution of microstructure and phase composition of Ti-3Al-5Mo-4.5V alloy with varied β phase stability显示文摘The microstructure evolution and phase composition of an α+β titanium alloy, Ti-3Al-5Mo-4.5V(wt.%),have been investigated. Electron probe micro analysis(EPMA) quantitative results manifest that the stability of β phase decreases with increasing quenching temperature, which is influenced by the significant variation of β-stabilizing elements concentration. Detailed microstructure analysis shows that the β→ωphase transformation does occur when quenching at 750℃ and 800 ℃. The ω-reflections change from incommensurate ω-spots(750 ℃) to ideal ω-spots(800 ℃) as the β stability of the alloy decreases. Further the decrease of β phase stability encourages the formation of athermal α ' martensite, which has the following orientation relationships: [111]β//[110]α',[100]p//[100]α ' and [-110]p//[00-1]α' with respect to the β matrix. | Q.Xue Y.J.Ma J.F.Lei R.Yang C.Wang | 2018 | Journal of Materials Science & Technology2018，34，12： | 8 |
| 8 | A digital earth prototype system:DEPS/CAS显示文摘Digital Earth is an information expression of the real Earth,and is a new way of understanding the Earth in the twenty-first century.This paper introduces a Digital Earth Prototype System(DEPS)developed at the Chinese Academy of Sciences(CAS)and supported by the Knowledge Innovation Program of the Chinese Academy of Sciences.Discussions are made to the theoretical model and technical framework of the Digital Earth,and its related key technologies on spatial information processing,spatial data warehouse technology,virtual reality technology,high-performance and parallel computing.The DEPS consists of seven sub-systems including the spatial data,metadata,model database,Grid geoscience computing,spatial information database,maps service and virtual reality.Meanwhile,we developed a series of application systems such as the environment monitoring for the Olympic Games 2008 in Beijing,natural disasters evaluation,digital city,digital archeology,Asia regional aerosol and climate change.The DEPS/CAS displayed the application ability and potential of the Digital Earth in three levels:the global,national and regional. | H.Guo X.Fan C.Wang | 2009 | International Journal of Digital Earth2009，2，1： | 5 |
| 9 | The Soft X-ray Imager(SXI)on the SMILE Mission显示文摘The Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.SMILE is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in 2025.SXI is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SMILE orbit.SXI is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s exosphere.SWCX provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field lines.The sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SMILE will enable such movements to be tracked for segments lasting many hours.SXI is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States. | S.Sembay A.L.Alme D.Agnolon T.Arnold A.Beardmore A.Belén Balado Margeli C.Bicknell C.Bouldin G.Branduardi-Raymont T.Crawford J.P.Breuer T.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor T.Crawford N.Eaton C.Feldman C.Forsyth T.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer M.Guedel Y.Guo M.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh M.W.J.Hubbard H.Jeszenszky M.Jones T.Kennedy K.Koch-Mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.Martindale J.Miguel Mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter T.Pouliantis B.H.Qureshi W.Raab G.Randal A.M.Read N.M.M.Roque M.E.Rostad C.Runciman S.Sachdev A.Samsonov M.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland M.Steller TianRan Sun J.Thornhill W.Thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang | 2024 | Earth and Planetary Physics2024，8，1： | 4 |
| 10 | Smart Cutting Tools and Smart Machining: Development Approaches, and Their Implementation and Application Perspectives显示文摘Smart machining has tremendous potential and is becoming one of new generation high value precision manufacturing technologies in line with the advance of Industry 4.0 concepts. This paper presents some innovative design concepts and, in particular, the development of four types of smart cutting tools, including a force-based smart cutting tool, a temperature-based internally-cooled cutting tool, a fast tool servo(FTS) and smart collets for ultraprecision and micro manufacturing purposes. Implementation and application perspectives of these smart cutting tools are explored and discussed particularly for smart machining against a number of industrial application requirements. They are contamination-free machining,machining of tool-wear-prone Si-based infra-red devices and medical applications, high speed micro milling and micro drilling, etc. Furthermore, implementation techniques are presented focusing on:(a) plug-and-produce design principle and the associated smart control algorithms,(b) piezoelectric film and surface acoustic wave transducers to measure cutting forces in process,(c) critical cutting temperature control in real-time machining,(d) inprocess calibration through machining trials,(e) FE-based design and analysis of smart cutting tools, and(f) application exemplars on adaptive smart machining. | Kai Cheng Zhi-Chao Niu Robin C.Wang Richard Rakowski Richard Bateman | 2017 | Chinese Journal of Mechanical Engineering2017，30，5： | 4 |
| 11 | Active Immunization to Prevent De Novo Hepatitis B Virus Infection in Pediatric Live Donor Liver Recipients显示文摘 | C.‐C.Lin C.‐L.Chen A.Concejero C.‐C.Wang S.‐H.Wang Y.‐W.Liu C.‐H.Yang C.‐C.Yong T.‐S.Lin B.Jawan Y.‐F.Cheng H.‐L.Eng | 2006 | American Journal of Transplantation2006，，1： | 4 |
| 12 | Non-Maxwellian electron distributions resulting from direct laser acceleration in near-critical plasmas显示文摘The irradiation of few-nm-thick targets by a finite-contrast high-intensity short-pulse laser results in a strong pre-expansion of these targets at the arrival time of the main pulse.The targets decompress to near and lower than critical densities with plasmas extending over few micrometers,i.e.multiple wavelengths.The interaction of the main pulse with such a highly localized but inhomogeneous target leads to the generation of a short channel and further self-focusing of the laser beam.Experiments at the Glass Hybrid OPCPA Scaled Test-bed(GHOST)laser system at University of Texas,Austin using such targets measured non-Maxwellian,peaked electron distribution with large bunch charge and high electron density in the laser propagation direction.These results are reproduced in 2D PIC simulations using the EPOCH code,identifying direct laser acceleration(DLA)[1]as the responsible mechanism.This is the first time that DLA has been observed to produce peaked spectra as opposed to broad,Maxwellian spectra observed in earlier experiments[2].This high-density electrons have potential applications as injector beams for a further wakefield acceleration stage as well as for pump-probe applications. | T.Toncian C.Wang E.McCary A.Meadows A.V.Arefiev J.Blakeney K.Serratto D.Kuk C.Chester R.Roycroft L.Gao H.Fu X.Q.Yan J.Schreiber I.Pomerantz A.Bernstein H.Quevedo G.Dyer T.Ditmire B.M.Hegelich | 2016 | Matter and Radiation at Extremes2016，1，1： | 3 |
| 13 | Investigation and assessment of micropollutants and associated biological effects in wastewater treatment processes显示文摘Currently,the wastewater treatment plants(WWTPs)attempt to achieve the shifting from general pollution parameters control to reduction of organic micropollutants discharge.However,they have not been able to satisfy the increasing ecological safety needs.In this study,the removal of micropollutants was investigated,and the ecological safety was assessed for a local WWTP.Although the total concentration of 31 micropollutants detected was reduced by 83%using the traditional biological treatment processes,the results did not reflect chemicals that had poor removal efficiencies and low concentrations.Of the five categories of micropollutants,herbicides,insecticides,and bactericides were difficult to remove,pharmaceuticals and UV filters were effectively eliminated.The specific photosynthesis inhibition effect and non-specific bioluminescence inhibition effect from wastewater were detected and evaluated using hazardous concentration where 5%of aquatic organisms are affected.The photosynthesis inhibition effect from wastewater in the WWTP was negligible,even the untreated raw wastewater.However,the bioluminescence inhibition effect from wastewater which was defined as the priority biological effect,posed potential ecological risk.To decrease non-specific biological effects,especially of macromolecular dissolved organic matter,overall pollutant reduction strategy is necessary.Meanwhile,the ozonation process was used to further decrease the bioluminescence inhibition effects from the secondary effluent;≥0.34 g O 3/g DOC of ozone dose was recommended for micropollutants elimination control and ecological safety. | Xiaoyan Y.Ma Ke Dong Lei Tang Yongkun Wang Xiaochang C.Wang Huu Hao Ngo Rong Chen Na Wang | 2020 | Journal of Environmental Sciences2020，32，8： | 3 |
| 14 | On the double-side probeless friction stir spot welding of AA2198 Al-Li alloy显示文摘Double-side probeless friction stir spot welding (DP-FSSW) of AA2198 alloy was conducted to investigate the microstructure and mechanical properties. Compared with common single-side probeless friction stir spot welding (P-FSSW), the plastic strain during DP-FSSW is nearly symmetrical with respect to the bondline to suppress the extension of hook defect, which is detrimental to the joint mechanical strength. With DP-FSSW, a fully metallurgically bonded region has formed due to severe plastic deformation at high temperatures. Tensile/shear tests show that the joint strength could exceed 8 kN, which is comparable to P-FSSW and refill FSSW, and all fractures happen in a shear failure mode as cracks extend along the in terface of two sheets. The microhard ness profile exhibits a uniform distribution along the thick ness direction, in which the hook defect shows the lowest value. | Q.Chu W.Y.Li H.L.Hou X.W.Yang A.Vairis C.Wang W.B.Wang | 2019 | Journal of Materials Science & Technology2019，35，5： | 3 |
| 15 | Ground-based and additional science support for SMILE显示文摘The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere ionosphere.Combining these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE mission.Here,we describe current community efforts to prepare for SMILE,and the benefits and context various experiments that have explicitly expressed support for SMILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these efforts.Preparations include constructing an online SMILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft conjunctions.We anticipate growing interest and community engagement with the SMILE mission,and we welcome novel ideas and insights from the solar-terrestrial community. | J.A.Carter M.Dunlop C.Forsyth K.Oksavik E.Donovon A.Kavanagh S.E.Milan T.Sergienko R.C.Fear D.G.Sibeck M.Connors T.Yeoman X.Tan M.G.G.T.Taylor K.McWilliams J.Gjerloev R.Barnes D.D.Billet G.Chisham A.Dimmock M.P.Freeman D.-S.Han M.D.Hartinger S.-Y.W.Hsieh Z.-J.Hu M.K.James L.Juusola K.Kauristie E.A.Kronberg M.Lester J.Manuel J.Matzka I.McCrea Y.Miyoshi J.Rae L.Ren F.Sigernes E.Spanswick K.Sterne A.Steuwer T.Sun M.-T.Walach B.Walsh C.Wang J.Weygand J.Wild J.Yan J.Zhang Q.-H.Zhang | 2024 | Earth and Planetary Physics2024，8，1： | 2 |
| 16 | Vascular Stents in the Management of Portal Venous Complications in Living Donor Liver Transplantation显示文摘 | Y.‐F.Cheng H.‐Y.Ou L. L.‐C.Tsang C.‐Y.Yu T.‐L.Huang T.‐Y.Chen A.Concejero C.‐C.Wang S.‐H.Wang T.‐S.Lin Y.‐W.Liu C.‐H.Yang C.‐C.Yong K.‐W.Chiu B.Jawan H.‐L.Eng C.‐L.Chen | 2010 | American Journal of Transplantation2010，，5： | 2 |
| 17 | 骶骨整块切除骨盆环重建治疗骶骨骨巨细胞瘤的疗效观察显示文摘目的:探讨骶骨整块切除及骨盆环重建治疗骶骨骨巨细胞瘤的方法与疗效。方法:2003年1月~2006年1月加州大学洛杉矶分校Santa Monica骨科医院脊柱外科中心收治骶骨骨巨细胞瘤患者8例,男5例,女3例,手术时年龄30~72岁,平均46岁。术前腰骶部CT扫描和MRI检查证实肿瘤均累及S1,采用一期前后路联合手术,术中结扎髂内动脉、髂腰动脉和骶正中动脉,显微镜下将肿瘤组织连同整块骶骨完整切除,用骨盆环假体重建腰骶髂关节稳定性。术后采用Toronto Extremity Salvage Score(TESS)评分系统对患者的功能恢复情况进行评价。结果:术中失血量800~2500ml,平均1200ml,手术时间490~720min,平均600min。病理学诊断:骨巨细胞瘤ⅡB期5例,Ⅲ期3例。术后卧床6~14d,平均10d,无1例患者术后并发切口感染。出院时患者均能不借助拐杖行走,恢复了日常生活自理能力。所有患者随访28~64个月,平均43个月,TESS评分由术前平均56.38分提高到73.25分。1例患者(Ⅲ期)术后18个月发生肺转移,接受肺叶切除,同时行放疗,随访至40个月时仍然存活;其余7例患者至末次随访时均存活,没有发现局部复发。结论:骶骨肿瘤累及S1时可行骶骨全切以提高肿瘤切除的彻底性,改善预后;采用骨盆环假体重建稳定性术后可早期活动。 | 蒋欣 韦竑宇 Yuichiro Morishita Hymanson Henry Jeffrey C.Wang | 2009 | 中国脊柱脊髓杂志2009，19，2： | 2 |
| 18 | Acceleration of 60 MeV proton beams in the commissioning experiment of the SULF-10 PW laser显示文摘We report the experimental results of the commissioning phase in the 10 PW laser beamline of the Shanghai Superintense Ultrafast Laser Facility(SULF).The peak power reaches 2.4 PW on target without the last amplifying during the experiment.The laser energy of 72±9 J is directed to a focal spot of approximately 6μm diameter(full width at half maximum)in 30 fs pulse duration,yielding a focused peak intensity around 2.0×10^(21)W/cm^(2).The first laser-proton acceleration experiment is performed using plain copper and plastic targets.High-energy proton beams with maximum cut-off energy up to 62.5 MeV are achieved using copper foils at the optimum target thickness of 4μm via target normal sheath acceleration.For plastic targets of tens of nanometers thick,the proton cut-off energy is approximately 20 MeV,showing ring-like or flamented density distributions.These experimental results reflect the capabilities of the SULF-10 PW beamline,for example,both ultrahigh intensity and relatively good beam contrast.Further optimization for these key parameters is underway,where peak laser intensities of 10^(22)-10^(23)w/cm^(2)are anticipated to support various experiments on extreme field physics. | A.X.Li C.Y.Qin H.Zhang S.Li L.L.Fan Q.S.Wang T.J.Xu N.W.Wang L.H.Yu Y.Xu Y.Q.Liu C.Wang X.L.Wang Z.X.Zhang X.Y.Liu P.L.Bai Z.B.Gan X.B.Zhang X.B.Wang C.Fan Y.J.Sun Y.H.Tang B.Yao X.Y.Liang Y.X.Leng B.F.Shen L.L.Ji R.X.Li Z.Z.Xu | 2022 | High Power Laser Science and Engineering2022，10，4： | 2 |
| 19 | Observation of the Crab Nebula with LHAASO-KM2A−a performance study显示文摘A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 TeV.Even though the detector construction is still underway,half of the KM2A array has been operating stably since the end of 2019.In this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray astronomy.We detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May 2020.With the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection power.The energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other experiments.This opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered. | F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi H.Cai J.T.Cai Z.Cao J.Chang J.F.Chang X.C.Chang B.M.Chen J.Chen L.Chen M.J.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.W.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai D.della Volpe B.D'Ettorre Piazzoli X.J.Dong J.H.Fan Y.Z.Fan Z.X.Fan J.Fang K.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao W.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu J.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He J.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.J.Hu D.H.Huang Q.L.Huang W.H.Huang X.T.Huang Z.C.Huang F.Ji X.L.Ji H.Y.Jia K.Jiang Z.J.Jiang C.Jin D.Kuleshov K.Levochkin B.B.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li J.Li K.Li W.L.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li E.W.Liang Y.F.Liang S.J.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu J.Liu J.L.Liu J.S.Liu J.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu W.Liu Y.N.Liu Z.X.Liu W.J.Long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao A.Masood W.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng J.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang W.W.Tian B.D.Wang C.Wang H.Wang H.G.Wang J.C.Wang J.S.Wang L.P.Wang L.Y.Wang R.N.Wang W.Wang X.G.Wang X.J.Wang X.Y.Wang Y.D.Wang Y.J.Wang Y.P.Wang Z.Wang Z.H.Wang Z.X.Wang D.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.W.Yang F.F.Yang J.Y.Yang L.L.Yang M.J.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng W.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang J.L.Zhang J.W.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao J.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou J.N.Zhou P.Zhou R.Zhou X.X.Zhou C.G.Zhu F.R.Zhu H.Zhu K.J.Zhu X.Zuo | 2021 | Chinese Physics C2021，45，2： | 2 |
| 20 | Effects of the physicochemical properties of gold nanostructures on cellular internalization显示文摘Unique physicochemical properties of Au nanomaterials make them potential star materials in biomedicalapplications. However, we still know a little about the basic problem of what really mattersin fabrication of Au nanomaterials which can get into biological systems, especially cells, with highefficiency. An understanding of how the physicochemical properties of Au nanomaterials affecttheir cell internalization is of significant interest. Studies devoted to clarify the functions of variousproperties of Au nanostructures such as size, shape and kinds of surface characteristics in cell internalizationare under way. These fundamental investigations will give us a foundation for constructingAu nanomaterial-based biomedical devices in the future. In this review, we present the current advancesand rationales in study of the relationship between the physicochemical properties of Aunanomaterials and cell uptake. We also provide a perspective on the Au nanomaterial-cell interactionresearch. | Ningqiang Gong Shizhu Chen Shubin Jin Jinchao Zhang Paul C.Wang Xing-Jie Liang | 2015 | Regenerative Biomaterials2015，2，4： | 2 |
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