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| 1 | Rheostatic Control of ABA Signaling through HOS15-Mediated OST1 Degradation显示文摘Dehydrating stresses trigger the accumulation of abscisic acid(ABA),a key plant stress-signaling hormone that activates Snf1-Related Kinases(SnRK2s)to mount adaptive responses.However,the regulatory circuits that terminate the SnRK2s signal relay after acclimation or post-stress conditions remain to be defined.Here,we show that the desensitization of the ABA signal is achieved by the regulation of OST1(SnRK2.6)protein stability via the E3-ubiquitin ligase HOS15.Upon ABA signal,HOS15-induced degradation of OST1 is inhibited and stabilized OST1 promotes the stress response.When the ABA signal terminates,protein phosphatases ABI1/2 promote rapid degradation of OST1 via HOS15.Notably,we found that even in the presence of ABA,OST1 levels are also depleted within hours of ABA signal onset.The unexpected dynamics of OST1 abundance are then resolved by systematic mathematical modeling,demonstrating a desensitizing feedback loop by which OST1-induced upregulation of ABI1/2 leads to the degradation of OST1.This model illustrates the complex rheostat dynamics underlying the ABA-induced stress response and desensitization. | Akhtar Ali Jae Kyoung Kim Masood Jan Haris Ali Khan Irfan Ullah Khan Mingzhe Shen Junghoon Park Chae Jin Lim Shah Hussain Dongwon Baek Kai Wang Woo Sik Chung Vicente Rubio Sang Yeol Lee Zhizhong Gong Woe Yeon Kim Ray ABressan Jose MPardo Dae-Jin Yun | 2019 | Molecular Plant2019，12，11： | 5 |
| 2 | Biomechanical pulping of Loblolly pine chips with selected whiterot fungi显示文摘 | Masood Akhtar Michael C Attridge Gary C Myers | 1993 | Holzforschung1993，47，1： | 1 |
| 3 | Field evaluation of Eimeria tenella (local isolates) gametocytes vaccine and its comparative efficacy with imported live vaccine, LivaCox?显示文摘 | M. Irfan Anwar Masood Akhtar Iftikhar Hussain A. U. Haq Faqir Muhammad M. Abdul Hafeez M. Shahid Mahmood Saira Bashir | 2008 | Parasitology Research2008，，1： | 1 |
| 4 | Biomechanical pulping:a mill- scale evaluation显示文摘 | MASOOD AKHTAR G M SCOTT R E SWANEY | 2000 | Resources conservation and recycling2000，28，： | 1 |
| 5 | Burnes using simons stain to predict energy savings during biomechanical pulping显示文摘 | Masood Akhtar Robert A Blanchette | 1995 | Wood and Fiber Science1995，27，3： | 1 |
| 6 | Biornechanical pulping of aspen wood chips with three stains of Ceriporiopsis subvermispora显示文摘 | Masood Akhtar | 1994 | Holzforschung1994，48，3： | 1 |
| 7 | Biomechanical pthping of loblolly pine with different strains of the white-rot fungus Ceriporiopsis subvermispora显示文摘 | Masood Akhtar Michael C Attridge Gary C Myers | 1992 | Tappi Journal1992，75，2： | 1 |
| 8 | ACP/ACC/AHA Task Force Statement: Clinical Competence Statement: Clinical Competence in Electrocardiography: A Statement for Physicians From the ACP/ACC/AHA Task Force on Clinical Privileges in Cardiology显示文摘 | Charles Fisch Thomas J. Ryan Sankey V. Williams James L. Achord Masood Akhtar Michael H. Crawford Gottlieb C. Friesinger Elmer J. Holzinger Francis J. Klocke Peter R. Kowey Risa J. Lavizzo-Mourey James Leonard John B. O’Connell Robert A. O’Rourke William | 1995 | Circulation1995，，： | 1 |
| 9 | Biomechanical pulping:a mill-scale evaluation显示文摘 | Masood Akhtar | 2000 | Resources Conservation and Recycling2000，28，： | 1 |
| 10 | Immunostimulatory and protective effects of Aloe vera against coccidiosis in industrial broiler chickens显示文摘 | Masood Akhtar Abdul Hai Mian Muhammad Awais Zafar Iqbal Faqir Muhammad Ahsan ul Haq Muhammad Irfan Anwar | 2011 | Veterinary Parasitology . 2011 (3-4)2011，，3： | 1 |
| 11 | Formulation and in vitro evaluation of a cosmetic emulsion from almond oil显示文摘 | Akhtar N Ahmad M-G Masood MI | 2008 | Pakistan Journal of Pharmaceutical Sciences2008，21，4： | 1 |
| 12 | Immunostimulatory and protective effects of Aloe vera against coc-cidiosis in industrial broiler chickens显示文摘 | Masood Akhtar Abdul Hai Mian Muhammad Awais Zafar Iqbal Faqir Muhammad Ahsan ul Haq Muhammad lrfan Anwar | 2012 | Veterinary Parasitology Volume 186 Issues 3-4 25 May 20122012，，： | 1 |
| 13 | Using Simons Stain to E- valuate Fiber Characteristic of Biomechanical Pulps显示文摘 | Robert A Blanchette Masood Akhtar | 1992 | Tappi J1992，11，： | 1 |
| 14 | Biomechanical pulping of Aspen Wood Chips With Three Strains of Ceriporiopsis Subvermispora 显示文摘 | Masood Akhtar | 1994 | Holzforschung1994，48，3： | 1 |
| 15 | Recurrence of neurocardiogenic syncope without pharmacologic interventions显示文摘 | Andrea Natale Mary Jane Geiger Cheryl Maglio Keith H. Newby Anwer Dhala Masood Akhtar Jasbir Sra | 1996 | The American Journal of Cardiology1996，，11： | 1 |
| 16 | Prevalence of Campylobacter species in meat, milk and other food commodities in Pakistan显示文摘 | Iftikhar Hussain Muhammad Shahid Mahmood Masood Akhtar Ahrar Khan | 2006 | Food Microbiology2006，，3： | 1 |
| 17 | Efficacy of itraconazole versusfluconazole in vaginal candidiasis 显示文摘 | Akhtar SI Masood S | 2012 | Pak Med Assoc2012，62，10： | 1 |
| 18 | Transcather mapping and radiofrequency ablation of cardiat arrhythmias 显示文摘 | Masood Akhtar | 1994 | Curt Probl Cardiol1994，19，： | 1 |
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