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101篇 您的检索式:作者名="MIRIAM S"
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1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: A prospective study显示文摘Javier Fernández Juan Acevedo Miriam Castro Orlando Garcia Carlos Rodríguez de Lope Daria Roca Marco Pavesi Elsa Sola Leticia Moreira Anibal Silva Tiago Seva‐Pereira Francesco Corradi Jose Mensa Pere Ginès Vicente Arroyo 2012Hepatology2012,,:4
3The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study显示文摘Donald S Silverberg Dov Wexler David Sheps Miriam Blum Gad Keren Ron Baruch Doron Schwartz Tatyana Yachnin Shoshana Steinbruch Itzhak Shapira Shlomo Laniado Adrian Iaina 2001Journal of the American College of Cardiology2001,,7:2
4Impact of osmotic/matric stress and heat shock on environmental tolerance induction of bacterial biocontrol agents against Fusarium vetticillioides显示文摘Melina S Andrea N Miriam E 2010Research in Microbiology2010,,161:1
5Fluorinated polyanilines as superior materials for electrocatalytic anodes in bacterial fuel cells 显示文摘Juliane N Uwe S Miriam R 2004Electrochemistry Communications2004,6,:1
6Array biosensor for detection of oehratoxin A in cereals and beverages 显示文摘Miriam M N Lias C S Martin H M 2005Analytical Chemistry2005,77,1:1
7MRI of the Sacroiliac Joints in Patients with Moderate to Severe Ankylosing Spondylitis 显示文摘Miriam A Bredella Lynne S 2006A JR2006,18,7:1
8Does the presence of hepatitis virus B and C influence the evolution of diffuse large B-cell lymphoma?显示文摘Judit Rubio Fernando Franco Antonio nchez Blanca Cantos Miriam ndez Virginia Calvo Constanza Maximiano David Perez Isabel Millá n Margarita nchez-Beato Mariano Provencio 2015Leukemia & Lymphoma2015,,6:1
9Strategies to prevent and control hepatitis B and C virus infections:a global perspective显示文摘 Miriam J Harold S 1999Vaccine1999,17,:1
10What do Boards Really Do?Evidence from Minutes of Board Meetings显示文摘Miriam Schwartz-Ziv Michael S Weisbach 2013Journal of Financial Economics2013,,108:1
11Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis显示文摘 Gerhard W Volkmar G 2004Brain2004,127,:1
12European Society of Hypertension guidelines for blood pressure monitoring at home: a summary report of the Second International Consensus Conference on Home Blood Pressure Monitoring显示文摘Gianfranco Parati George S Stergiou Roland Asmar Grzegorz Bilo Peter de Leeuw Yutaka Imai Kazuomi Kario Empar Lurbe Athanasios Manolis Thomas Mengden Eoin O?Brien Takayoshi Ohkubo Paul Padfield Paolo Palatini Thomas Pickering Josep Redon Miriam Revera Lui 2008Journal of Hypertension2008,,8:1
13Suicide report indicates shift at WHO显示文摘Miriam S 2014Canadian Medical Association Journal2014,186,14:1
14Lack of association between intussusception and oral polio vaccine in Cuban children显示文摘Miguel A. Galindo Sardi?as Andrés Zambrano Cárdenas Gisele Coutin Marie Manuel Santin Pe?a Miriam Ali?o Santiago Marlen Valcárcel Sanchez C.P. Farrington 2001European Journal of Epidemiology2001,,8:1
15The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combina- tion with CA125 in the differential diagnosis of ovarian masses 显示文摘Miriam L Petra S Linda H 2011Clinical chemistry and laboratory medicine2011,49,12:1
16Origin of trisomy 21 in Down syndrome case from a Spanish population registry显示文摘David G Eulalia S Miriam G 2000Annales de Genetique2000,43,:1
17Impact of positive end-expiratory pressure on the definition of acute respiratory distress syndrome显示文摘Elisa Estenssoro Arnaldo Dubin Enrique Laffaire Héctor S Canales Gabriela Sáenz Miriam Moseinco Pierina Bachetti 2003Intensive Care Medicine2003,,11:1
18Advanced oxidation products as novel mediators of inflammation and monocyte activation in chronic renal failure显示文摘Veronique W S Mitko S Miriam F 1998J Immunol1998,161,:1
19Extraction and Clean-up Preocedure for Analysis of Organochlorine Pesticide Residues in Ethoxylated Lanolin显示文摘LUCIANA P MIRIAM S ANA P d O S 2000J II Farmaco2000,55,:1
20Human I-defensin 3 inhibits cell wall biosynthesis in Staphylococci显示文摘Vera S Tanja S Miriam W 2010Infect Immun2010,78,6:1
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