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| 1 | Broadband achromatic metalens in terahertz regime显示文摘Achromatic focusing is essential for broadband operation, which has recently been realised from visible to infrared wavelengths using a metasurface. Similarly, multi-terahertz functional devices can be encoded in a desired metasurface phase profile. However, metalenses suffer from larger chromatic aberrations because of the intrinsic dispersion of each unit element. Here, we propose an achromatic metalens with C-shaped unit elements working from 0.3 to 0.8 THz with a bandwidth of approximately 91% over the centre frequency. The designed metalens possesses a high working efficiency of more than 68% at the peak and a relatively high numerical aperture of 0.385. We further demonstrate the robustness of our Cshaped metalens, considering lateral shape deformations and deviations in the etching depth. Our metalens design opens an avenue for future applications of terahertz meta-devices in spectroscopy, time-offlight tomography and hyperspectral imaging systems. | Qingqing Cheng Meilin Ma Dong Yu Zhixiong Shen Jingya Xie Juncheng Wang Nianxi Xu Hanming Guo Wei Hu Shuming Wang Tao Li Songlin Zhuang | 2019 | Science Bulletin2019，64，20： | 16 |
| 2 | Recent Advances in Space-Deployable Structures in China显示文摘Deployable space structure technology is an approach used in building spacecraft,especially when realizing deployment and folding functions.Once in orbit,the structures are released from the fairing,deployed,and positioned.With the development of communication,remote-sensing,and navigation satellites,space-deployable structures have become cutting-edge research topics in space science and technology.This paper summarizes the current research status and development trend of spacedeployable structures in China,including large space mesh antennas,space solar arrays,and deployable structures and mechanisms for deep-space exploration.Critical technologies of space-deployable structures are addressed from the perspectives of deployable mechanisms,cable-membrane form-finding,dynamic analysis,reliable environmental adaptability analysis,and validation.Finally,future technology developments and trends are elucidated in the fields of mesh antennas,solar arrays,deployable mechanisms,and on-orbit adjustment,assembly,and construction. | Xiaofei Ma Tuanjie Li Jingya Ma Zhiyi Wang Chuang Shi Shikun Zheng Qifeng Cui Xiao Li Fan Liu Hongwei Guo Liwu Liu Zuowei Wang Yang Li | 2022 | Engineering2022，，10： | 6 |
| 3 | The Dry-Cold Climate of the Qijia Archeological Civilization in Chankou of the Loess Plateau along the Silk Road Since the Neolithic Period显示文摘Objective Large numbers of archeological relics from the Neolithic period are widely distributed in all tributaries of the Yellow River.The early humans tended to reside along the river valleys,and developed small but characteristically decentralized ancient valley culture.It is universally acknowledged that the agriculture exchange between China and western countries and the moderate climate pushed the Neolithic culture prosperity (Chen et al.,2015;Liu Lian et al.,2016;An Chengbang et al.,2017). | ZHANG Huirong DEMBELE Blaise ZHANG Wanyi ZHANG Jingya MA Yuan ZHANG Chengjun | 2018 | Acta Geologica Sinica(English Edition)2018，92，6： | 4 |
| 4 | Rice Interploidy Crosses Disrupt Epigenetic Regulation, Gene Expression, and Seed Development显示文摘在被子植物的种子开发在内乳要求 2:1 maternal-to-paternal 染色体比率(2m:1p ) 。当比率被破坏时,种子发展被损害。瑞斯 interploidy 十字导致内乳失败,但是内在的分子的机制仍然保持不清楚。这里,我们报导在米饭 interploidy 十字的有缺点的内乳与小 RNA 和编码蛋白质的基因的 nonadditive 表示被联系。有趣地, 24-nt 小介入 RNA 被充实在 5 和 3 ? flanking 序列 nonadditively 在 interploidy 十字表示了基因并且否定地与印的基因的表示被联系。而且,一些 PRC2 家庭基因和 DNA 包括 OsMET1b 和 OsCMT3a 的 methylation 相关的基因是在 2 湡散愠摮椠据敲獡摥礠敩摬鵸?鵸 的 upregulated?? | Limei Wang Jingya Yuan Yujie Ma Wu Jiao Wenxue Ye Dong-Lei Yang Chuandeng Yi Z. Jeffrey Chen | 2018 | Molecular Plant2018，11，2： | 3 |
| 5 | Berry syndrome: a rare cardiac malformation with extra-cardiac findings显示文摘Dear Editor,Berry syndrome is a rare combination of congenital cardiac malformations characterized by four abnormal features;namely,an aortopulmonary window(APW),aortic origin of the right pulmonary artery,hypoplasia or interruption of the aortic arch,with an intact ventricular septum.The disease was first reported by Berry in 1982,who estimated the incidence within the population with congenital cardiac malformations to be 0.046%(Berry et al.,1982).Until recently, | Jingya Li Ya Yang Xiaomin Duan Lanzhong Jin Lin Zheng Xin Zhang Haiyan Wei Yan Sun Xiaolin Zhang Pei Li Jiao Yang Ning Ma Fangyun Wang | 2017 | Science China(Life Sciences)2017，60，7： | 3 |
| 6 | Multi-label learning algorithm with SVM based association显示文摘Multi-label learning is an active research area which plays an important role in machine learning. Traditional learning algorithms, however, have to depend on samples with complete labels. The existing learning algorithms with missing labels do not consider the relevance of labels, resulting in label estimation errors of new samples. A new multi-label learning algorithm with support vector machine(SVM) based association(SVMA) is proposed to estimate missing labels by constructing the association between different labels. SVMA will establish a mapping function to minimize the number of samples in the margin while ensuring the margin large enough as well as minimizing the misclassification probability. To evaluate the performance of SVMA in the condition of missing labels, four typical data sets are adopted with the integrity of the labels being handled manually. Simulation results show the superiority of SVMA in dealing with the samples with missing labels compared with other models in image classification. | 冯攀 Qin Danyang Ji Ping Ma Jingya Zhang Yan Yang Songxiang | 2019 | High Technology Letters2019，25，1： | 3 |
| 7 | Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function显示文摘The AMP-activated protein kinase(AMPK)is a central regulator of energy homeostasis.Although much has been learned on how low energy status and glucose starvation activate AMPK,how AMPK activity is properly controlled in vivo is still poorly understood.Here we report that UHRF1,an epigenetic regulator highly expressed in proliferating and cancer cells,interacts with AMPK and serves to suppress AMPK activity under both basal and stressed conditions.As a nuclear protein,UHRF1 promotes AMPK nuclear retention and strongly suppresses nuclear AMPK activity toward substrates H2B and EZH2.Importantly,we demonstrate that UHRF1 also robustly inhibits AMPK activity in the cytoplasm compartment,most likely as a consequence of AMPK nucleocytoplasmic shuttling.Mechanistically,we found that UHRF1 has no obvious effect on AMPK activation by upstream kinases LKB1 and CAMKK2 but inhibits AMPK activity by acting as a bridging factor targeting phosphatase PP2A to dephosphorylate AMPK.Hepatic overexpression of UHRF1 showed profound effects on glucose and lipid metabolism in wild-type mice but not in those with the liver-specific knockout of AMPKα1/α2,whereas knockdown of UHRF1 in adipose tissue led to AMPK activation and reduced sizes of adipocytes and lipogenic activity,highlighting the physiological significance of this regulation in glucose and lipid metabolism.Thus,our study identifies UHRF1 as a novel AMPK gate-keeper with critical roles in cellular metabolism. | Xiang Xu Guangjin Ding Caizhi Liu Yuhan Ding Xiaoxin Chen Xiaoli Huang Chen-Song Zhang Shanxin Lu Yunpeng Zhang Yuanyong Huang Zhaosu Chen Wei Wei Lujian Liao Shu-Hai Lin Jingya Li Wei Liu Jiwen Li Sheng-Cai Lin Xinran Ma Jiemin Wong | 2022 | Cell Research2022，32，1： | 3 |
| 8 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 9 | Synergic Inhibition of Lung Carcinoma 95-D Cell Proliferation and Invasion by Combination with(—)-Epigallocatechin-3-Gallate and Ascorbic Acid显示文摘 | MA Yan YANG Jingya LI Shiyi YU Wenjuan | 2018 | Wuhan University Journal of Natural Sciences2018，23，3： | 1 |
| 10 | OvBNN authentication based on cooperative signature for wireless sensor networks显示文摘The universality of the application of wireless sensor networks( WSN) makes more attention be paid on the security problem. Node authentication is not only the basis of network security,but also the premise of key management and secure routing protocol. Although the signature mechanism based on symmetric encryption is high in energy efficiency,it is vulnerable to be attacked and there is a time delay during authentication. Traditional public key encryption mechanism with improvement in security brings in complex algorithm and costs much time,which is not suitable for WSN. In this paper,a signature authentication mechanism,an optimized variant Bellare Namprempre Neven( OvBNN) is presented to quickly complete the authentication by mutual cooperation between nodes so as to make the nodes use the intermediate calculation results of their neighbor nodes directly.Simulation results show that the proposed mechanism is superior to traditional authentication mechanisms both in energy consumption and authentication time. | 秦丹阳 Zhang Yan Ma Jingya Ji Ping | 2018 | High Technology Letters2018，24，3： | 1 |
| 11 | Genome-wide CRISPR screening reveals key genes and pathways associated with 20-hydroxyecdysone signal transduction in the silkworm(Bombyx mori)显示文摘Metamorphosis is a complex developmental process involving multiple pathways and a large number of genes that are regulated by juvenile hormone(JH)and 20-hydroxyecdysone(20E).Despite important progress in understanding various aspects of silkworm biology,the hormone signaling pathway in the silkworm remains poorly understood.Genome-wide screening using clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)-based libraries has recently emerged as a novel method for analyzing genome function,enabling further research into essential genes,drug targets,and virus-host interaction.Previously,we constructed a genome-wide CRISPR/Cas9-based library of the silkworm(Bombyx mori)and successfully revealed the genes involved in biotic or abiotic stress factor responses.In this study,we used our silkworm CRISPR library and large-scale genome-wide screening to analyze the key genes in the silkworm 20E signaling pathway and their mechanisms of action.Functional annotation showed that 20E regulates key proteins in processes that mainly occur in the cytoplasm and nucleus.Pathway enrichment analysis showed that 20E can activate phosphorylation and may affect innate immunity,interfere with intracellular nutrition and energy metabolism,and eventually cause cell apoptosis.The screening results were experimentally validated by generating cells with knockout alleles of the relevant genes,which had increased tolerance to 20E.Our findings provide a panoramic overview of signaling in response to 20E in the silkworm,underscoring the utility of genome-wide CRISPR mutant libraries in deciphering hormone signaling pathways and the mechanisms that regulate metamorphosis in insects. | Hao Sun Jingya Chen Ruolin Wang Dan Liu Na Zhang Tong Zhang Ling Jia Sanyuan Ma Qingyou Xia | 2024 | Insect Science2024，31，1： | 0 |
| 12 | Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas显示文摘Medulloblastoma(MB)is one of the most common childhood malignant brain tumors(WHO grade IV),traditionally divided into WNT,SHH,Group 3,and Group 4 subgroups based on the transcription profiles,somatic DNA alterations,and clinical outcomes.Unlike WNT and SHH subgroup MBs,Group 3 and Group 4 MBs have similar transcriptomes and lack clearly specific drivers and targeted therapeutic options.The recently revised WHO Classification of CNS Tumors has assigned Group 3 and 4 to a provisional non-WNT/SHH entity.In the present study,we demonstrate that Kir2.1,an inwardly-rectifying potassium channel,is highly expressed in non-WNT/SHH MBs,which promotes tumor cell invasion and metastasis by recruiting Adam10 to enhance S2 cleavage of Notch2 thereby activating the Notch2 signaling pathway.Disruption of the Notch2 pathway markedly inhibited the growth and metastasis of Kir2.1-overexpressing MB cell-derived xenograft tumors in mice.Moreover,Kir2.1^(high)/nuclear N2ICD^(high)MBs are associated with the significantly shorter lifespan of the patients.Thus,Kir2.1^(high)/nuclear N2ICD^(high)can be used as a biomarker to define a novel subtype of non-WNT/SHH MBs.Our findings are important for the modification of treatment regimens and the development of novel-targeted therapies for non-WNT/SHH MBs. | Yan-Xia Wang Haibo Wu Yong Ren Shengqing Lv Chengdong Ji Dongfang Xiang Mengsi Zhang Huimin Lu Wenjuan Fu Qing Liu Zexuan Yan Qinghua Ma Jingya Miao Ruili Cai Xi Lan Bin Wu Wenying Wang Yinhua Liu Dai-Zhong Wang Mianfu Cao Zhicheng He Yu Shi Yifang Ping Xiaohong Yao Xia Zhang Peng Zhang Ji Ming Wang Yan Wang Youhong Cui Xiu-Wu Bian | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 0 |
| 13 | Body composition characteristics of Uyghur college students and their correlation with lifestyles显示文摘This paper aims to analyze the characteristics of body composition changes of Uygur collegestudents and explore the correlation between their body composition and lifestyle.A cross-sectional investigationwas conducted on 526 Uygur students(264 males and 262 females)by using the stratified cluster samplingmethod.Questionnaires were used to study their lifestyles,and bioimpedance analyzers were used to measure thebody composition-related indicators.It was found that there were gender differences in various body compositionindicators of Uyghur college students at different ages,and the average value reached a peak in the 21-year-oldgroup.The average BMI,the average BFP and the average WHR were within normal ranges.Compared withother college student groups recently reported,the obesity rate was relatively lower.The proportion of Uyghurgirls with abnormal BFP was higher than that of boys,and the proportion of boys with abnormal WHR and VAIindexes was higher than that of girls.Exercise status was negatively correlated with fat mass,BFP and WHR,and positively correlated with other indicators.Therefore,Uygur college students'body composition indicatorsvary with gender and age.Exercise has a significant effect on many body composition indicators of Uygur collegestudents,and can effectively improve the proportion of body composition. | Bai Jingya He Ye Ma Bin Wang Yutang He Jinquan Hai Xiangjun | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 14 | Delayed diagnosis for tricuspid regurgitation after blunt chest trauma显示文摘Tricuspid valve regurgitation is a rare complication of blunt chest trauma.Approximately 150 cases have been reported since first being described by Todd et al in 1848.1 During the past few decades traumatic tricuspid regurgitation has been reported with increasing frequency,which may in part be attributed to more patients surviving blunt chest trauma as well as improved diagnostic imaging studies,such as echocardiography.The incidence of traumatic tricuspid regurgitation is likely underestimated since chronic,isolated tricuspid insufficiency may be well tolerated in some patients who experience few or no symptoms after the traumatic event.2 Furthermore,some patients may not recall antecedent chest trauma unless specifically questioned.Most cases of traumatic tricuspid regurgitation are secondary to blunt chest trauma. | Zhao Haige Robert A. McCready Fan Jingya Hu Peng Ni Yiming Dominige Calcaterra Ma Liang | 2014 | Chinese Medical Journal2014，，9： | 0 |
| 15 | Study on key management scheme for heterogeneous wireless sensor networks显示文摘Heterogeneous wireless sensor network( HWSN) is composed of different functional nodes and is widely applied. With the deployment in hostile environment,the secure problem of HWSN is of great importance; moreover,it becomes complex due to the mutual characteristics of sensor nodes in HWSN. In order to enhance the network security,an asymmetric key pre-distributed management scheme for HWSN is proposed combining with authentication process to further ensure the network security; meanwhile,an effective authentication method for newly added nodes is presented. Simulation result indicates that the proposed scheme can improve the network security while reducing the storage space requirement efficiently. | 秦丹阳 Ma Jingya Zhang Yan Yang Songxiang Ji Ping Feng Pan | 2018 | High Technology Letters2018，24，4： | 0 |
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